Gene

Asap3

Species
Mus musculus
Symbol
Asap3
Name
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
Synonyms
  • 9430088F20Rik
  • Ddefl1
Biotype
protein coding gene
Automated Description
Predicted to enable GTPase activator activity. Predicted to be involved in cell migration; positive regulation of GTPase activity; and regulation of stress fiber assembly. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in focal adhesion; intracellular membrane-bounded organelle; and ruffle. Orthologous to human ASAP3 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 3).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45854
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensASAP310 of 10YesYes  
Rattus norvegicusAsap39 of 9YesYes   
Danio rerioasap38 of 10YesYes  
Drosophila melanogasterAsap6 of 9YesNo   
Saccharomyces cerevisiaeAGE12 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Asap21101360434 of 9 
Asap1286962454 of 9 
Acap3389236233 of 9 
Agap24100232212 of 9 
Arap3590634222 of 9 
Acap2678739243 of 9 
Acap1772939253 of 9 
Appl1884235192 of 9 
Agap3974433222 of 9 
Arap21057935232 of 9 
Git21158633212 of 9 
Git11252835222 of 9 
Arfgap21350035222 of 9 
Arfgap31451132222 of 9 
Smap21540137242 of 9 
Agap11630049332 of 9 
Appl21740339212 of 9 
Arap11834138252 of 9 
Adap11915347332 of 9 
Adap22010451372 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
abnormal coat/hair pigmentation
abnormal vocalization
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

No mapped variant information available
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
Asap3em4Gpt
  • Asap3em4Cd6060
allele
Asap3em1(IMPC)Jallele
Yes
Asap3em1Gpt
  • Asap3em1Cflox
allele
Asap3tm1Smoc
  • ASAP3loxP
allele
Asap3em1Cya
  • Asap3em1
allele
NC_000070.7:g.135935005A>Gvariant
SNP
  • intron variant
NC_000070.7:g.135935101T>Gvariant
SNP
  • intron variant
NC_000070.7:g.135935166T>Cvariant
SNP
  • intron variant
NC_000070.7:g.135936004C>Tvariant
SNP
  • intron variant
NC_000070.7:g.135936509G>Cvariant
SNP
  • intron variant
Showing 1 - 10 of 1,329 rows
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Transgenic Alleles

No data available

Models

Model name
Experimental condition
Associated Human Diseases
Associated Phenotypes
Modifier
Source
Asap3em1(IMPC)J/Asap3em1(IMPC)J [background:] C57BL/6NJ-Asap3em1(IMPC)J/Mmjax
  • abnormal coat/hair pigmentation
  • abnormal vocalization
MGI
Showing 1 - 1 of 1 rows
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Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
135.935M135.940M135.945M135.950M135.955M135.960M135.965M135.970MENSMUST00000047526 (Asap3)NM_001008232.2 (Asap3)NM_001355698.1 (Asap3)XM_006538761.3 (Asap3)XM_011250233.4 (Asap3)XR_390738.5 (Asap3)

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available