Gene

Mctp1

Species
Rattus norvegicus
Symbol
Mctp1
Name
multiple C2 and transmembrane domain containing 1
Synonyms
  • LOC309928
  • Mctp1-ps1
Biotype
protein coding gene
Automated Description
Predicted to enable calcium ion binding activity. Involved in negative regulation of cell migration; negative regulation of endocytosis; and negative regulation of response to oxidative stress. Located in recycling endosome and synaptic vesicle membrane. Orthologous to human MCTP1 (multiple C2 and transmembrane domain containing 1).
RGD Description
Predicted to enable calcium ion binding activity. Involved in negative regulation of cell migration; negative regulation of endocytosis; and negative regulation of response to oxidative stress. Located in recycling endosome and synaptic vesicle membrane. Orthologous to human MCTP1 (multiple C2 and transmembrane domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; diclofenac; gentamycin.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45911
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensMCTP110 of 10YesYes  
Mus musculusMctp19 of 9YesYes   
Xenopus tropicalismctp14 of 9YesYes   
Danio reriomctp1a9 of 9YesYes   
Danio reriomctp1b3 of 9NoYes   
Drosophila melanogasterMctp8 of 9YesYes   
Caenorhabditis elegansmctp-19 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Mctp2190163467 of 9 
Syt7272936252 of 9 
Rasal1379434202 of 9 
Esyt2473136222 of 9 
Esyt3561936222 of 9 
Rph3a658436252 of 9 
Rasa4762035222 of 9 
Esyt182 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

No mapped variant information available
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051337.1:g.6291906A>Tvariant
SNP
  • intron variant
NC_051337.1:g.6294425A>Gvariant
SNP
  • intron variant
NC_051337.1:g.6294637T>Gvariant
SNP
  • intron variant
NC_051337.1:g.6304203A>Gvariant
SNP
  • intron variant
NC_051337.1:g.6409208G>Avariant
SNP
  • intron variant
NC_051337.1:g.6414572A>Cvariant
SNP
  • intron variant
NC_051337.1:g.6427003T>Avariant
SNP
  • intron variant
NC_051337.1:g.6434369T>Cvariant
SNP
  • intron variant
NC_051337.1:g.6314716T>Avariant
SNP
  • intron variant
NC_051337.1:g.6316182T>Gvariant
SNP
  • intron variant
Showing 1 - 10 of 1,685 rows
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Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
6.1M6.2M6.3M6.4M6.5M6.6M6.7MENSRNOT00000017828.9 (Mctp1)ENSRNOT00000064743.4 (Mctp1)ENSRNOT00000093593.2 (Mctp1)NM_001376934.1 (Mctp1)XM_039102152.2 (Mctp1)XM_039102153.2 (Mctp1)XM_039102154.2 (Mctp1)XM_039102155.2 (Mctp1)XM_039102156.2 (Mctp1)XM_039102158.2 (Mctp1)Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

1 interactor gene based on 1 annotation
Mctp1 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Mib1Rattus norvegicus
protein
  • affinity chromatography technology
PMID:25931508
Showing 1 - 1 of 1 rows
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Genetic Interactions

No data available