Gene

Nudt21

Species
Rattus norvegicus
Symbol
Nudt21
Name
nudix hydrolase 21
Synonyms
  • cleavage and polyadenylation specific factor 5
  • cleavage and polyadenylation specificity factor subunit 5
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including histone deacetylase binding activity; mRNA 3'-UTR AU-rich region binding activity; and protein homodimerization activity. Predicted to contribute to RNA binding activity. Predicted to be involved in several processes, including mRNA 3'-end processing; positive regulation of cell differentiation; and protein heterotetramerization. Predicted to be located in centriolar satellite; cytoplasm; and paraspeckles. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human NUDT21 (nudix hydrolase 21).
RGD Description
Predicted to enable several functions, including histone deacetylase binding activity; mRNA 3'-UTR AU-rich region binding activity; and protein homodimerization activity. Predicted to contribute to RNA binding activity. Predicted to be involved in several processes, including mRNA 3'-end processing; positive regulation of cell differentiation; and protein heterotetramerization. Predicted to be located in centriolar satellite; cytoplasm; and paraspeckles. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human NUDT21 (nudix hydrolase 21); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; mRNA decay pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; Brodifacoum.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13047
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensNUDT2110 of 10YesYes  
Mus musculusNudt219 of 9YesYes   
Danio rerionudt219 of 9YesYes   
Caenorhabditis eleganscfim-19 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
10.976M10.978M10.980M10.982M10.984M10.986M10.988M10.990M10.992M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051354.1:g.10975428A>Gvariant
SNP
  • intron variant
NC_051354.1:g.10981239A>Gvariant
SNP
  • intron variant
NC_051354.1:g.10986244G>Avariant
SNP
  • intron variant
NC_051354.1:g.10989139A>Gvariant
SNP
  • intron variant
NC_051354.1:g.10991029A>Gvariant
SNP
  • 3 prime UTR variant
NC_051354.1:g.10981076A>Gvariant
SNP
  • intron variant
NC_051354.1:g.10981130A>Gvariant
SNP
  • intron variant
NC_051354.1:g.10988275G>Avariant
SNP
  • intron variant
NC_051354.1:g.10974763C>Tvariant
SNP
  • 5 prime UTR variant
NC_051354.1:g.10976374A>Gvariant
SNP
  • intron variant
Showing 1 - 10 of 77 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
10.976M10.978M10.980M10.982M10.984M10.986M10.988M10.990M10.992MENSRNOT00000026297.7 (Nudt21)ENSRNOT00000096044.1 (Nudt21)ENSRNOT00000111115.1 (Nudt21)NM_001039004.1 (Nudt21)ENSRNOT00000026118.8 (Ogfod1)ENSRNOT00000112630.1 (Ogfod1)ENSRNOT00000115629.1 (Ogfod1)NM_001107411.3 (Ogfod1)

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

4 interactor genes based on 4 annotations
Nudt21 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Mapk14Mus musculus
protein
  • proximity labelling technology
PMID:31505169
protein
MaptRattus norvegicus
protein
  • affinity chromatography technology
PMID:32357304
protein
Park7Rattus norvegicus
protein
  • affinity chromatography technology
PMID:16854843
protein
SncaRattus norvegicus
protein
  • affinity chromatography technology
PMID:16854843
Showing 1 - 4 of 4 rows
per page

Genetic Interactions

No data available