Version: 8.1.0
Date: Fri Apr 18 2025
Tnfsf13
Rattus norvegicusRGD:1305871
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Tnfsf13

Species
Rattus norvegicus
Symbol
Tnfsf13
Name
TNF superfamily member 13
Synonyms
  • April
  • LOC287437
Biotype
protein coding gene
Automated Description
Predicted to enable receptor ligand activity. Predicted to be involved in positive regulation of B cell proliferation and positive regulation of isotype switching to IgA isotypes. Predicted to act upstream of or within immunoglobulin mediated immune response; positive regulation of cell population proliferation; and positive regulation of germinal center formation. Predicted to be located in cytoplasm and external side of plasma membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Orthologous to human TNFSF13 (TNF superfamily member 13).
RGD Description
Predicted to enable receptor ligand activity. Predicted to be involved in positive regulation of B cell proliferation and positive regulation of isotype switching to IgA isotypes. Predicted to act upstream of or within immunoglobulin mediated immune response; positive regulation of cell population proliferation; and positive regulation of germinal center formation. Predicted to be located in cytoplasm and external side of plasma membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Orthologous to human TNFSF13 (TNF superfamily member 13); PARTICIPATES IN adaptive immune response pathway; cytokine mediated signaling pathway; rheumatoid arthritis pathway; INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15151
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensTNFSF1310 of 10YesYes☑☑☑☑☑☑☑☑☑☑  
Mus musculusTnfsf139 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Danio reriotnfsf137 of 9YesYes☐ ☑☑☐☑☑☑☑☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Tnfsf13b126446313 of 9☑☐☐☐☐☐☑☑☐ 
Tnfsf12225838252 of 9☑☐☐☐☐☐☑☐☐ 
Eda318240252 of 9☐☐☐☐☐☐☑☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    NC_051345.1:g.54403559T>Cvariant
    SNP
    • intron variant
    NC_051345.1:g.54401000T>Cvariant
    SNP
    • intron variant
    NC_051345.1:g.54403704C>Tvariant
    SNP
    • 5 prime UTR variant
    NC_051345.1:g.54401683G>Avariant
    SNP
    • intron variant
    NC_051345.1:g.54400060C>Tvariant
    SNP
    • 3 prime UTR variant
    Showing 1 - 5 of 5 rows
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    View detailed Alleles/Variants information
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available