Version: 8.0.0
Date: Tue Jan 28 2025
Mei1
Rattus norvegicusRGD:1307210
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Mei1

Species
Rattus norvegicus
Symbol
Mei1
Name
meiotic double-stranded break formation protein 1
Synonyms
  • LOC315162
  • meiosis defective 1
Biotype
protein coding gene
Automated Description
Predicted to be involved in meiosis I. Predicted to act upstream of or within germ cell development; meiotic nuclear division; and meiotic spindle organization. Human ortholog(s) of this gene implicated in gestational trophoblastic neoplasm. Orthologous to human MEI1 (meiotic double-stranded break formation protein 1).
RGD Description
Predicted to be involved in meiosis I. Predicted to act upstream of or within germ cell development; meiotic nuclear division; and meiotic spindle organization. Human ortholog(s) of this gene implicated in gestational trophoblastic neoplasm. Orthologous to human MEI1 (meiotic double-stranded break formation protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12044
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensMEI110 of 10YesYes☑☑☑☑☑☑☑☑☑☑  
Mus musculusMei19 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Xenopus tropicalismei15 of 9YesYes☑ ☐☐☑☑☐☑☑☐  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Bcl2l11110439282 of 9☑☐☐☐☐☐☑☐☐ 
Scimp22167522 of 9☑☐☐☐☐☐☑☐☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    NC_051342.1:g.113612749C>Tvariant
    SNP
    • intron variant
    NC_051342.1:g.113624253T>Cvariant
    SNP
    • intron variant
    NC_051342.1:g.113608101G>Avariant
    SNP
    • intron variant
    NC_051342.1:g.113628940C>Tvariant
    SNP
    • splice region variant
    NC_051342.1:g.113630300A>Gvariant
    SNP
    • intron variant
    NC_051342.1:g.113632973C>Tvariant
    SNP
    • intron variant
    NC_051342.1:g.113637970C>Avariant
    SNP
    • intron variant
    NC_051342.1:g.113605940C>Avariant
    SNP
    • intron variant
    NC_051342.1:g.113603443C>Tvariant
    SNP
    • intron variant
    NC_051342.1:g.113604297C>Tvariant
    SNP
    • intron variant
    Showing 1 - 10 of 213 rows
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    View detailed Alleles/Variants information
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available