Species

Rattus norvegicus

Symbol

Slmap

Name

sarcolemma associated protein

Synonyms

LOC290533
sarcolemmal membrane-associated protein

Biotype

protein coding gene

Automated Description

Predicted to enable protein-macromolecule adaptor activity and small GTPase binding activity. Predicted to be involved in several processes, including negative regulation of hippo signaling; regulation of membrane depolarization during cardiac muscle cell action potential; and regulation of voltage-gated sodium channel activity. Predicted to be located in membrane. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in cytoplasm. Orthologous to human SLMAP (sarcolemma associated protein).

RGD Description

Predicted to enable protein-macromolecule adaptor activity and small GTPase binding activity. Predicted to be involved in several processes, including negative regulation of hippo signaling; regulation of membrane depolarization during cardiac muscle cell action potential; and regulation of voltage-gated sodium channel activity. Predicted to be located in membrane. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in cytoplasm. Orthologous to human SLMAP (sarcolemma associated protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Cross References

Additional Information

Literature

Orthology

Gene tree: PANTHER:PTHR15715

Stringency:StringentModerateNo filter

Additional filters to further constrain the results:

Best Score OnlyBest Reverse Score Only

Count:Species:Methods:

Species	Gene symbol	Count	Best	Best reverse	Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiens	SLMAP	9 of 10	Yes	Yes	☐☑☑☑☑☑☑☑☑☑
Mus musculus	Slmap	8 of 9	Yes	Yes	☐ ☑☑☑☑☑☑☑☑
Xenopus tropicalis	slmap	8 of 9	Yes	Yes	☐ ☑☑☑☑☑☑☑☑
Drosophila melanogaster	Slmap	5 of 9	Yes	Yes	☐ ☐☐☐☑☑☑☑☑
Caenorhabditis elegans	slmp-1	5 of 9	Yes	Yes	☐ ☐☐☐☑☑☑☑☑
Saccharomyces cerevisiae S288C	FAR10	3 of 9	Yes	Yes	☐ ☐☐☐☑☑☑☐☐
Saccharomyces cerevisiae S288C	VPS64	3 of 9	Yes	Yes	☐ ☐☐☐☑☑☑☐☐

Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse

Paralogy

Gene symbol	Rank	Alignment Length (aa)	Similarity %	Identity %	Method Count	Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Ccdc136	1	416	47	28	3 of 9	☑☐☐☐☐☐☑☑☐
Traf3ip3	2	325	51	28	3 of 9	☑☐☐☐☐☐☑☑☐

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources: None
Other Sources: None

No data available

Disease Associations

Must provide at least one subject

Cell color indicative of annotation volume

Species	Gene	Association	Disease Qualifier	Disease	Evidence	Source	Based On	References
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Alleles and Variants

Genome location

Chr16:1667205...1785200 - (118.00 kb)

Assembly version

mRatBN7.2

Viewer Help

Data currently unavailable; sequence viewer under construction

Allele/Variant Symbol	Category	Variant
NC_051351.1:g.1744558G>C	variant	rs3322850404 SNP intron variant
NC_051351.1:g.1694472C>A	variant	NC_051351.1:g.1694472C>A SNP intron variant
NC_051351.1:g.1726859G>T	variant	rs3322909232 SNP intron variant
NC_051351.1:g.1728380G>C	variant	rs3322850447 SNP intron variant
NC_051351.1:g.1769031A>C	variant	rs3322923904 SNP intron variant
NC_051351.1:g.1780052C>T	variant	rs3322850481 SNP intron variant
NC_051351.1:g.1712110T>C	variant	rs3322854219 SNP intron variant
NC_051351.1:g.1780116G>A	variant	rs3322902136 SNP intron variant
NC_051351.1:g.1780594G>A	variant	rs3322850483 SNP intron variant
NC_051351.1:g.1762871G>A	variant	rs3322850460 SNP intron variant