Version: 8.0.0Date: Tue Jan 28 2025
Gene
Tdrd3
- Species
- Rattus norvegicus
- Symbol
- Tdrd3
- Name
- tudor domain containing 3
- Synonyms
- LOC306066
- tudor domain-containing protein 3
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable chromatin binding activity; methylated histone binding activity; and transcription coactivator activity. Predicted to be involved in chromatin organization and positive regulation of DNA-templated transcription. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be part of DNA topoisomerase III-beta-TDRD3 complex and exon-exon junction complex. Predicted to be active in nucleus. Orthologous to human TDRD3 (tudor domain containing 3).
- RGD Description
- Predicted to enable chromatin binding activity; methylated histone binding activity; and transcription coactivator activity. Predicted to be involved in chromatin organization and positive regulation of DNA-templated transcription. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be part of DNA topoisomerase III-beta-TDRD3 complex and exon-exon junction complex. Predicted to be active in nucleus. Orthologous to human TDRD3 (tudor domain containing 3); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR13681
Stringency:
Additional filters to further constrain the results:
| Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
|---|---|---|---|---|---|
| Homo sapiens | TDRD3 | 10 of 10 | Yes | Yes | ☑☑☑☑☑☑☑☑☑☑ |
| Mus musculus | Tdrd3 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Xenopus tropicalis | tdrd3 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Danio rerio | tdrd3 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Drosophila melanogaster | Tdrd3 | 8 of 9 | Yes | Yes | ☑ ☑☑☑☐☑☑☑☑ |
| Caenorhabditis elegans | Y50D4C.3 | 7 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☐☐ |
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Paralogy
| Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
|---|---|---|---|---|---|---|
| Smndc1 | 1 | 84 | 54 | 36 | 2 of 9 | ☐☐☐☐☐☐☑☑☐ |
Disease Associations
Cases where the expected disease association was NOT found
| all annotations | all disease by infectious agent | bacterial infectious disease | fungal infectious disease | parasitic infectious disease | viral infectious disease | all disease of anatomical entity | cardiovascular system disease | central nervous system disease | endocrine system disease | gastrointestinal system disease | hematopoietic system disease | immune system disease | integumentary system disease | musculoskeletal system disease | peripheral nervous system disease | reproductive system disease | respiratory system disease | sensory system disease | thoracic disease | urinary system disease | all disease of cellular proliferation | benign neoplasm | cancer | pre-malignant neoplasm | all genetic disease | chromosomal disease | monogenic disease | polygenic disease | all other disease | disease of mental health | disease of metabolism | physical disorder | syndrome | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tdrd3 (Rno) |
Cell color indicative of annotation volume
No data available
Alleles and Variants
- Genome location
- Chr15:63340531...63497208 + (156.68 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
| NC_051350.1:g.63423689G>A | variant | SNP
| |||||
| NC_051350.1:g.63386562C>T | variant | SNP
| |||||
| NC_051350.1:g.63387992G>A | variant | SNP
| |||||
| NC_051350.1:g.63409798G>T | variant | SNP
| |||||
| NC_051350.1:g.63412007C>T | variant | SNP
| |||||
| NC_051350.1:g.63412611C>G | variant | SNP
| |||||
| NC_051350.1:g.63373632C>A | variant | SNP
| |||||
| NC_051350.1:g.63373702G>C | variant | SNP
| |||||
| NC_051350.1:g.63388546C>A | variant | SNP
| |||||
| NC_051350.1:g.63427460A>T | variant | SNP
| |||||
Sequence Feature Viewer
- Genome location
- Chr15:63340531...63497208 + (156.68 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- None
- Other Sources
| all annotations | all anatomical structures | alimentary part of gastrointestinal system | chemosensory system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | mechanosensory system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | sensory system | vestibulo-auditory system | visual system | endoderm | ectoderm | mesoderm | mesenchyme | adipose tissue | appendage | entire extraembryonic component | imaginal precursor | pharyngeal arch | other | all stages | embryo stage | post embryonic, pre-adult | post-juvenile adult stage | all cellular components | extracellular region | plasma membrane | synapse | cell junction | cell projection | cytoplasmic vesicle | endosome | vacuole | golgi apparatus | endoplasmic reticulum | cytosol | mitochondrion | nucleus | chromosome | cytoskeleton | protein-containing complex | other locations | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tdrd3 (Rno) |
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.
Molecular Interactions
1 interactor gene based on 1 annotation
Tdrd3 molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
|---|---|---|---|---|---|---|
protein | Mib1 | Rattus norvegicus | protein |
| PMID:25931508 |
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