Version: 8.0.0
Date: Tue Jan 28 2025
Tmtc1
Rattus norvegicusRGD:1564868
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Tmtc1

Species
Rattus norvegicus
Symbol
Tmtc1
Name
transmembrane O-mannosyltransferase targeting cadherins 1
Synonyms
  • LOC362465
  • RGD1564868
Biotype
protein coding gene
Automated Description
Predicted to enable dolichyl-phosphate-mannose-protein mannosyltransferase activity. Predicted to be involved in protein O-linked mannosylation. Predicted to be located in endoplasmic reticulum and membrane. Orthologous to human TMTC1 (transmembrane O-mannosyltransferase targeting cadherins 1).
RGD Description
Predicted to enable dolichyl-phosphate-mannose-protein mannosyltransferase activity. Predicted to be involved in protein O-linked mannosylation. Predicted to be located in endoplasmic reticulum and membrane. Orthologous to human TMTC1 (transmembrane O-mannosyltransferase targeting cadherins 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR44809
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensTMTC110 of 10YesYes☑☑☑☑☑☑☑☑☑☑  
Mus musculusTmtc19 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Xenopus tropicalistmtc19 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Danio reriotmtc19 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Tmtc3193748312 of 9☑☐☐☐☐☐☐☑☐ 
Tmtc2297344312 of 9☑☐☐☐☐☐☐☑☐ 
Tmtc4389647332 of 9☑☐☐☐☐☐☐☑☐ 
Ogt450641252 of 9☑☐☐☐☐☐☐☑☐ 
Ttc13547939222 of 9☑☐☐☐☐☐☐☑☐ 
Ttc16653332192 of 9☑☐☐☐☐☐☐☑☐ 
Bbs4743839222 of 9☑☐☐☐☐☐☐☑☐ 
Ift88842440232 of 9☑☐☐☐☐☐☐☑☐ 
Ttc8941040192 of 9☑☐☐☐☐☐☐☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    NC_051339.1:g.181152341G>Avariant
    SNP
    • intron variant
    NC_051339.1:g.181153714G>Cvariant
    SNP
    • intron variant
    NC_051339.1:g.181222447A>Gvariant
    NC_051339.1:g.181250271G>Avariant
    NC_051339.1:g.181322025G>Avariant
    SNP
    • intron variant
    NC_051339.1:g.181175178C>Gvariant
    SNP
    • intron variant
    NC_051339.1:g.181175183C>Tvariant
    SNP
    • intron variant
    NC_051339.1:g.181175299G>Cvariant
    SNP
    • intron variant
    NC_051339.1:g.181175758C>Tvariant
    SNP
    • intron variant
    NC_051339.1:g.181175798A>Gvariant
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available