Version: 8.1.0Date: Fri Apr 18 2025
Gene
Srr
- Species
- Rattus norvegicus
- Symbol
- Srr
- Name
- serine racemase
- Synonyms
- D-serine ammonia-lyase
- D-serine dehydratase
- Biotype
- protein coding gene
- Automated Description
- Enables several functions, including heterocyclic compound binding activity; magnesium ion binding activity; and protein homodimerization activity. Involved in alpha-amino acid metabolic process; response to ketamine; and response to xenobiotic stimulus. Located in apical part of cell. Orthologous to human SRR (serine racemase).
- RGD Description
- Enables several functions, including heterocyclic compound binding activity; magnesium ion binding activity; and protein homodimerization activity. Involved in alpha-amino acid metabolic process; response to ketamine; and response to xenobiotic stimulus. Located in apical part of cell. Orthologous to human SRR (serine racemase); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; nonketotic hyperglycinemia pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR43050
Stringency:
Additional filters to further constrain the results:
| Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
|---|---|---|---|---|---|
| Homo sapiens | SRR | 10 of 10 | Yes | Yes | ☑☑☑☑☑☑☑☑☑☑ |
| Mus musculus | Srr | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Xenopus tropicalis | srr | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Danio rerio | srr | 2 of 9 | Yes | Yes | ☐ ☐☑☐☐☐☐☐☑ |
| Drosophila melanogaster | Srr | 3 of 9 | Yes | Yes | ☐ ☐☑☐☐☑☐☐☑ |
| Caenorhabditis elegans | serr-1 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Saccharomyces cerevisiae S288C | SRY1 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available
Alleles and Variants
- Genome location
- Chr10:59769563...59787011 - (17.45 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
| NC_051345.1:g.59783231G>A | variant | SNP
| |||||
| NC_051345.1:g.59783941G>A | variant | SNP
| |||||
| NC_051345.1:g.59772839G>A | variant | SNP
| |||||
| NC_051345.1:g.59782622G>A | variant | SNP
| |||||
| NC_051345.1:g.59785501A>C | variant | SNP
| |||||
| NC_051345.1:g.59770593C>T | variant | SNP
| |||||
| NC_051345.1:g.59780692G>A | variant | SNP
| |||||
| NC_051345.1:g.59775154C>A | variant | SNP
| |||||
| NC_051345.1:g.59783315T>C | variant | SNP
| |||||
| NC_051345.1:g.59775247T>C | variant | SNP
| |||||
Sequence Feature Viewer
- Genome location
- Chr10:59769563...59787011 - (17.45 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- None
- Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.
Molecular Interactions
Srr molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection method | Source | Reference |
|---|---|---|---|---|---|---|
protein | Fbxo22 | Rattus norvegicus | protein | affinity chromatography technology | PMID:25336657 | |
protein | Mapk1 | Rattus norvegicus | protein | affinity chromatography technology | PMID:30053369 |
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