Species

Saccharomyces cerevisiae

Symbol

YLF2

Name

Not Available

Synonyms

YHL014C
YLF1

Biotype

protein coding gene

Automated Description

Predicted to enable ATP hydrolysis activity and GTP binding activity. Located in mitochondrion. Orthologous to human OLA1 (Obg like ATPase 1).

SGD Description

Protein of unknown function; has weak similarity to E. coli GTP-binding protein gtp1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies

Cross References

Additional Information

Literature

Orthology

Gene tree: PANTHER:PTHR23305:SF9

Stringency:StringentModerateNo filter

Additional filters to further constrain the results:

Best Score OnlyBest Reverse Score Only

Count:Species:Methods:

Species	Gene symbol	Count	Best	Best reverse	Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiens	OLA1	3 of 9	Yes	No	☑ ☐☐☐☐☐☑☑☐
Mus musculus	Ola1	3 of 9	Yes	No	☑ ☐☐☐☐☐☑☑☐
Rattus norvegicus	Ola1	3 of 9	Yes	No	☑ ☐☐☐☐☐☑☑☐
Xenopus tropicalis	ola1	3 of 9	Yes	No	☑ ☐☐☐☐☐☑☑☐
Danio rerio	ola1	3 of 9	Yes	No	☑ ☐☐☐☐☐☑☑☐
Caenorhabditis elegans	ola-1	3 of 9	Yes	No	☑ ☐☐☐☐☐☑☑☐

Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources

SGD

Other Sources

None

Phenotype Term

Annotation details

References

decreased acid pH resistance

View

PMID:15334557

decreased competitive fitness

View

PMID:18622397

decreased resistance to chemicals

View

Name	Type	Experimental condition	References
ylf2-Δ	allele	has condition: chemical: chondramide derivative	PMID:24360837
ylf2-Δ	allele	has condition: chemical: myriocin	PMID:24360837
ylf2-Δ	allele	has condition: chemical: alborixin	PMID:24360837

PMID:24360837

decreased stress resistance

View

PMID:33198745

decreased toxin resistance

View

PMID:23104007

haploinsufficient

View

PMID:22244311

haploproficient

View

Name	Type	Experimental condition	Modifier	References
ylf2-Δ	allele	has condition: treatment: conditions that mimic Phase II of a batch fermentation, equivalent to ~22 hours after inoculation of a batch fermentation		PMID:24040173

PMID:24040173

increased competitive fitness

View

Name	Type	Experimental condition	References
ylf2-Δ	allele	has condition: media: glycerol medium, YPG	PMID:23103169
ylf2-Δ	allele	has condition: media: rich medium (YPD) w/6% ethanol, ETH	PMID:23103169
ylf2-Δ	allele	has condition: chemical: ethanol	PMID:23103169

PMID:23103169

increased sporulation efficiency

View

PMID:12432101

viable

View

PMID:12140549

Showing 1 - 10 of 10 rows

per page

1

Disease Associations

Must provide at least one subject

Cell color indicative of annotation volume

Species	Gene	Association	Disease Qualifier	Disease	Evidence	Source	Based On	References
No records match query. Try removing filters.

Showing 0 - 0 of 0 rows

per page

Alleles and Variants

Genome location

ChrVIII:76097...77314 - (1.22 kb)

Assembly version

R64-5-1

Viewer Help

Data currently unavailable; sequence viewer under construction

Allele/Variant Symbol	Allele Synonyms	Category	Variant
ylf2-Δ	ylf2-delta	allele		Yes
NC_001140.6:g.77106A>G		variant	NC_001140.6:g.77106A>G SNP missense variant
NC_001140.6:g.76481C>T		variant	NC_001140.6:g.76481C>T SNP synonymous variant
NC_001140.6:g.76095A>G		variant	NC_001140.6:g.76095A>G SNP intergenic variant
NC_001140.6:g.76534G>A		variant	NC_001140.6:g.76534G>A SNP synonymous variant
NC_001140.6:g.76691C>T		variant	NC_001140.6:g.76691C>T SNP synonymous variant
NC_001140.6:g.76976C>A		variant	NC_001140.6:g.76976C>A SNP missense variant
NC_001140.6:g.77306A>G		variant	NC_001140.6:g.77306A>G SNP intergenic variant
NC_001140.6:g.76673C>T		variant	NC_001140.6:g.76673C>T SNP synonymous variant
NC_001140.6:g.77201G>A		variant	NC_001140.6:g.77201G>A SNP intergenic variant

Showing 1 - 10 of 15 rows

per page

1
2
>

View detailed Alleles/Variants information

Download all Alleles/Variants for all genes of the species

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location

ChrVIII:76097...77314 - (1.22 kb)

Assembly version

R64-5-1

Viewer Help

Data currently unavailable; sequence viewer under construction

Sequence Details

Loading...

Expression

Primary Sources

Other Sources

Must provide at least one subject

Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

71 interactor genes based on 80 annotations

YLF2 molecule type	Interactor gene	Interactor species	Interactor molecule type	Detection methods	Source	Reference
RNA	CAF20	Saccharomyces cerevisiae	protein	affinity chromatography technology	biogrid:2874121	PMID:25973932
protein	CBP3	Saccharomyces cerevisiae	protein	proximity labelling technology	biogrid:2881750	PMID:32877643
protein	CBR1	Saccharomyces cerevisiae	protein	affinity chromatography technology	biogrid:186874	PMID:16554755
RNA	CCR4	Saccharomyces cerevisiae	protein	affinity chromatography technology	biogrid:2354386	PMID:29158339
RNA	DHH1	Saccharomyces cerevisiae	protein	affinity chromatography technology	biogrid:2351131	PMID:29158339
protein	EFT1	Saccharomyces cerevisiae	protein	affinity chromatography technology	biogrid:186872	PMID:16554755
protein	EFT1	Saccharomyces cerevisiae	protein	affinity chromatography technology	biogrid:186877	PMID:16554755
protein	EFT2	Saccharomyces cerevisiae	protein	affinity chromatography technology	biogrid:186872	PMID:16554755
protein	EFT2	Saccharomyces cerevisiae	protein	affinity chromatography technology	biogrid:186877	PMID:16554755
protein	ESA1	Saccharomyces cerevisiae	protein	enzymatic study	biogrid:336190	PMID:19303850

Showing 1 - 10 of 30 rows

per page

1
2
3
>

Genetic Interactions

YLF2 role	Interactor gene	Interactor species	Interactor role	Interaction type	Phenotype or trait	Source	Reference
unspecified role	ALA1	Saccharomyces cerevisiae	unspecified role	negative genetic interaction (sensu BioGRID)	colony size	biogrid:2046606	PMID:27708008
unspecified role	APC2	Saccharomyces cerevisiae	unspecified role	positive genetic interaction (sensu BioGRID)	colony size	biogrid:1896337	PMID:27708008
unspecified role	ARP3	Saccharomyces cerevisiae	unspecified role	positive genetic interaction (sensu BioGRID)	colony size	biogrid:1885637	PMID:27708008
unspecified role	CDC3	Saccharomyces cerevisiae	unspecified role	negative genetic interaction (sensu BioGRID)	colony size	biogrid:2046597	PMID:27708008
unspecified role	CDC7	Saccharomyces cerevisiae	unspecified role	negative genetic interaction (sensu BioGRID)	colony size	biogrid:2046583	PMID:27708008
unspecified role	CDC11	Saccharomyces cerevisiae	unspecified role	negative genetic interaction (sensu BioGRID)	colony size	biogrid:2046595	PMID:27708008
unspecified role	CDC24	Saccharomyces cerevisiae	unspecified role	negative genetic interaction (sensu BioGRID)	colony size	biogrid:2046577	PMID:27708008
unspecified role	CDC27	Saccharomyces cerevisiae	unspecified role	negative genetic interaction (sensu BioGRID)	colony size	biogrid:2046578	PMID:27708008
unspecified role	CDC28	Saccharomyces cerevisiae	unspecified role	negative genetic interaction (sensu BioGRID)	colony size	biogrid:2046580	PMID:27708008
unspecified role	CDC48	Saccharomyces cerevisiae	unspecified role	negative genetic interaction (sensu BioGRID)	colony size	biogrid:2046584	PMID:27708008

Showing 1 - 10 of 50 rows

per page

1
2
3
4
5
>