Gene

acs-13

Species
Caenorhabditis elegans
Symbol
acs-13
Name
fatty Acid CoA Synthetase family 13
Synonyms
  • CELE_Y65B4BL.5
  • Y65B4BL.5
Biotype
protein coding gene
Automated Description
Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty acid metabolic process. Predicted to be active in endoplasmic reticulum and membrane. Is expressed in body wall musculature; head; hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in acute myeloid leukemia; congenital diarrhea; and leukemia. Orthologous to human ACSL1 (acyl-CoA synthetase long chain family member 1); ACSL5 (acyl-CoA synthetase long chain family member 5); and ACSL6 (acyl-CoA synthetase long chain family member 6).
WB Description
Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Expressed in head. Human ortholog(s) of this gene implicated in acute myeloid leukemia; congenital diarrhea; and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1); ACSL5 (acyl-CoA synthetase long chain family member 5); and ACSL6 (acyl-CoA synthetase long chain family member 6).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43272
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensACSL67 of 9YesYes   
Homo sapiensACSL57 of 9YesYes   
Homo sapiensACSL17 of 9YesYes   
Mus musculusAcsl17 of 9YesYes   
Mus musculusAcsl67 of 9YesYes   
Mus musculusAcsl57 of 9YesYes   
Rattus norvegicusAcsl17 of 9YesYes   
Rattus norvegicusAcsl67 of 9YesYes   
Rattus norvegicusAcsl57 of 9YesYes   
Xenopus tropicalisacsl67 of 9YesYes   
Xenopus tropicalisacsl17 of 9YesYes   
Xenopus tropicalisacsl53 of 9NoYes   
Danio rerioacsl27 of 9YesYes   
Danio rerioacsl1b7 of 9YesYes   
Danio rerioacsl1a7 of 9YesYes   
Danio rerioacsl57 of 9YesYes   
Drosophila melanogasterCG39619 of 9YesYes   
Saccharomyces cerevisiaeFAA25 of 9YesNo   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
acs-5169662437 of 8  
acs-18269656397 of 8  
acs-15367857407 of 8  
acs-3463457366 of 8  
acs-17569447303 of 8  
acs-4666047312 of 8  
acs-14745141242 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
WBcel235
Viewer Help
512k513k514k515k516k517k518k519k
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_003279.8:g.514176G>Tvariant
SNP
  • missense variant
NC_003279.8:g.511532C>Tvariant
SNP
  • synonymous variant
NC_003279.8:g.512431A>Tvariant
SNP
  • intron variant
NC_003279.8:g.515685C>Tvariant
SNP
  • intron variant
NC_003279.8:g.517673C>Tvariant
SNP
  • intron variant
NC_003279.8:g.517999G>Avariant
SNP
  • intron variant
NC_003279.8:g.516006T>Avariant
SNP
  • intron variant
NC_003279.8:g.519050C>Tvariant
SNP
  • intron variant
NC_003279.8:g.519349C>Tvariant
SNP
  • intron variant
NC_003279.8:g.518651G>Avariant
SNP
  • intron variant
Showing 1 - 10 of 127 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
512k513k514k515k516k517k518k519kY65B4BL.5a.1 (acs-13)Y65B4BL.5b.1 (acs-13)Y65B4BL.5c.1 (acs-13)Y65B4BL.7a.1 (Y65B4BL.7)Y65B4BL.7a.2 (Y65B4BL.7)Y65B4BL.7b.1 (Y65B4BL.7)Y65B4BL.7c.1 (Y65B4BL.7)Y65B4BL.10Y65B4BL.9

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

16 interactor genes based on 16 annotations
acs-13 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
act-5Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:36261024
protein
akir-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:30036395
DNA
atfs-1Caenorhabditis elegans
protein
  • chromatin immunoprecipitation assay
PMID:25773600
protein
ccar-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:38126797
protein
ced-3Caenorhabditis elegans
protein
  • enzymatic study
PMID:15122042
protein
endu-2Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:37443152
protein
gras-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:36809245
protein
hda-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:34003109
protein
igdb-2Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:28803967
protein
pgl-3Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:26912668
Showing 1 - 10 of 16 rows
per page

Genetic Interactions

No data available