Version: 8.0.0Date: Tue Jan 28 2025
Gene
cblb
- Species
- Xenopus tropicalis
- Symbol
- cblb
- Name
- Cbl proto-oncogene B, E3 ubiquitin protein ligase
- Synonyms
- Cbl proto-oncogene B, E3 ubiquitin protein ligase
- cblb
- Biotype
- gene
- Automated Description
- Predicted to enable calcium ion binding activity; phosphotyrosine residue binding activity; and ubiquitin-protein transferase activity. Predicted to act upstream of or within regulation of platelet-derived growth factor receptor-alpha signaling pathway. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; stomach carcinoma; and type 1 diabetes mellitus. Orthologous to human CBLB (Cbl proto-oncogene B).
- XBXT Description
- Tyrosine kinase negative regulator CBLhttps://www.xenbase.org/gene/showgene.do?method=display&geneId=1018101
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- Not Available
Stringency:
Additional filters to further constrain the results:
| Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
|---|---|---|---|---|---|
| Homo sapiens | CBLB | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Mus musculus | Cblb | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Rattus norvegicus | Cblb | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
| Xenopus laevis | cblb.L | 1 of 1 | Yes | Yes | ☑ |
| Xenopus laevis | cblb.S | 1 of 1 | Yes | Yes | ☑ |
| Danio rerio | cblb | 8 of 9 | Yes | Yes | ☐ ☑☑☑☑☑☑☑☑ |
| Drosophila melanogaster | Cbl | 7 of 9 | Yes | Yes | ☐ ☑☑☐☑☑☑☑☑ |
| Caenorhabditis elegans | sli-1 | 5 of 9 | Yes | Yes | ☐ ☑☐☐☐☑☑☑☑ |
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species | Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
|---|---|---|---|---|---|---|---|---|
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Sequence Feature Viewer
- Genome location
- Chr02:99485068...99588194 - (103.13 kb)
- Assembly version
- XT9.1
- Viewer Help
Data currently unavailable; sequence viewer under construction