Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: signaling Biological Process: negative regulation of protein secretion
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, MGC1571, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2
Source: HGNC:613
Biotype: protein coding gene
INS
(Homo sapiens)Gene
Name: insulin
Synonyms: IRDN, proinsulin, preproinsulin, insulin-dependent diabetes mellitus 2, PNDM4, IDDM, ILPR, insulin isoform U3B, MODY10, IDDM1, IDDM2
Source: HGNC:6081
Biotype: protein coding gene
Prkn
(Mus musculus)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkinson disease (autosomal recessive, juvenile) 2, parkin, Park2, Parkin, Park
Source: MGI:1355296
Biotype: protein coding gene
FBN1
(Homo sapiens)Gene
Name: fibrillin 1
Synonyms: ACMICD, OCTD, fibrillin-1 preproprotein, MFLS, fibrillin 15, asprosin, Weill-Marchesani syndrome, ECTOL1, fibrillin-1, SSKS, MFS1, FBN, MASS, GPHYSD2, WMS, WMS2, SGS
Source: HGNC:3603
Biotype: protein coding gene
Fbn1
(Mus musculus)Gene
Name: fibrillin 1
Synonyms: expressed sequence AI536462, Fib-1, tight skin, AI536462, Tsk
Source: MGI:95489
Biotype: protein coding gene
Il1b
(Mus musculus)Gene
Name: interleukin 1 beta
Synonyms: IL-1F2, IL-1B, IL-1beta, Il-1b
Source: MGI:96543
Biotype: protein coding gene
IL1B
(Homo sapiens)Gene
Name: interleukin 1 beta
Synonyms: preinterleukin 1 beta, IL1F2, interleukin-1 beta, catabolin, IL-1, IL1-BETA, IL1beta, IL-1 beta, interleukin 1beta, interleukin 1, beta, pro-interleukin-1-beta
Source: HGNC:5992
Biotype: protein coding gene
GNAO1
(Homo sapiens)Gene
Name: G protein subunit alpha o1
Synonyms: heterotrimeric guanine nucleotide-binding protein 1G, DKFZp686O0962, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, G-ALPHA-o, EIEE17, guanine nucleotide-binding protein G(o) subunit alpha, guanine nucleotide binding protein, alpha activating polypeptide O, HG1G, GNAO, DEE17, NEDIM, GO2-q chimeric G-protein, HLA-DQB1, guanine nucleotide-binding regulatory protein 2
Source: HGNC:4389
Biotype: protein coding gene
Drd2
(Mus musculus)Gene
Name: dopamine receptor D2
Synonyms: D2R, Drd-2, D2 receptor
Source: MGI:94924
Biotype: protein coding gene
Ppp3ca
(Mus musculus)Gene
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Synonyms: AW413465, RIKEN cDNA 2900074D19 gene, AI841391, CN, calcineurin, Calna1, expressed sequence AW413465, 2900074D19Rik, CnA, expressed sequence AI841391, calcineurin, alpha subunit, Calna, PP2BA alpha, PP2B alpha 1, Caln
Source: MGI:107164
Biotype: protein coding gene
PRKN
(Homo sapiens)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: Parkinson disease (autosomal recessive, juvenile) 2, parkin, PDJ, parkinson disease protein 2, LPRS2, parkinson protein 2, E3 ubiquitin protein ligase (parkin), E3 ubiquitin ligase, AR-JP, parkin 2, PARK2, E3 ubiquitin-protein ligase parkin, parkinson juvenile disease protein 2, parkinson protein 2 E3 ubiquitin protein ligase
Source: HGNC:8607
Biotype: protein coding gene
FOXO1
(Homo sapiens)Gene
Name: forkhead box O1
Synonyms: forkhead box protein O1, forkhead, Drosophila, homolog of, in rhabdomyosarcoma, FOXO1A, forkhead homolog in rhabdomyosarcoma, forkhead in rhabdomyosarcoma, FKH1, forkhead box protein O1A, FKHR
Source: HGNC:3819
Biotype: protein coding gene
Kcnj11
(Mus musculus)Gene
Name: potassium inwardly rectifying channel, subfamily J, member 11
Synonyms: Kir6.2, expressed sequence AI842722, expressed sequence AW491124, AW491124, AI842722
Source: MGI:107501
Biotype: protein coding gene
DRD2
(Homo sapiens)Gene
Name: dopamine receptor D2
Synonyms: D2DR, dopamine D2 receptor, D2R, dopamine receptor D2 isoform, D(2) dopamine receptor, dopamine receptor 2, seven transmembrane helix receptor
Source: HGNC:3023
Biotype: protein coding gene
Ffar3
(Mus musculus)Gene
Name: free fatty acid receptor 3
Synonyms: Gm478, gene model 478, (NCBI), Gpr41, LOC233080, G protein-coupled receptor 41
Source: MGI:2685324
Biotype: protein coding gene
Nos1
(Mus musculus)Gene
Name: nitric oxide synthase 1, neuronal
Synonyms: NO, nitric oxide synthase 1 (macrophage), nNOS, RIKEN cDNA 2310005C01 gene, Nos-1, 2310005C01Rik, bNOS
Source: MGI:97360
Biotype: protein coding gene
NR1H3
(Homo sapiens)Gene
Name: nuclear receptor subfamily 1 group H member 3
Synonyms: LXR-a, nuclear receptor subfamily 1, group H, member 3, oxysterols receptor LXR-alpha, LXRA, RLD-1, CHOP, liver X nuclear receptor alpha variant 1, liver X receptor alpha, TLS/CHOP, liver X receptor, alpha, liver X receptor-alpha
Source: HGNC:7966
Biotype: protein coding gene
Syt4
(Mus musculus)Gene
Name: synaptotagmin IV
Synonyms: Not Available
Source: MGI:101759
Biotype: protein coding gene
KCNB1
(Homo sapiens)Gene
Name: potassium voltage-gated channel subfamily B member 1
Synonyms: delayed rectifier potassium channel Kv2.1, h-DRK1 K(+) channel, KV2.1, DRK1, DEE26, delayed rectifier potassium channel 1, potassium channel, voltage gated Shab related subfamily B, member 1, voltage-gated potassium channel subunit Kv2.1, potassium voltage-gated channel, Shab-related subfamily, member 1, h-DRK1, EIEE26, potassium channel protein DRK1
Source: HGNC:6231
Biotype: protein coding gene
Ins2
(Mus musculus)Gene
Name: insulin II
Synonyms: maturity onset diabetes of the young, maturity onset diabetes of the young 4, Mody, CP-II, InsII, expressed sequence AA986540, Ins-2, Mody4, AA986540
Source: MGI:96573
Biotype: protein coding gene
Drd3
(Rattus norvegicus)Gene
Name: dopamine receptor D3
Synonyms: D3 receptor, dopaminergic receptor D3, D(3) dopamine receptor, dopamine D3 receptor isoform, dopamine D3 receptor
Source: RGD:2521
Biotype: protein coding gene
ACVR1C
(Homo sapiens)Gene
Name: activin A receptor type 1C
Synonyms: activin A receptor type IC, ACVRLK7, ACTR-IC, ALK7, activin A receptor, type IC, activin receptor-like kinase 7, activin receptor type IC, ALK-7, activin receptor type-1C
Source: HGNC:18123
Biotype: protein coding gene
Apoe
(Rattus norvegicus)Gene
Name: apolipoprotein E
Synonyms: apo-E, APOEA
Source: RGD:2138
Biotype: protein coding gene
Ccn3
(Mus musculus)Gene
Name: cellular communication network factor 3
Synonyms: nephroblastoma overexpressed gene, Nov, CCN3, C130088N23Rik, RIKEN cDNA C130088N23 gene
Source: MGI:109185
Biotype: protein coding gene
Adra2a
(Mus musculus)Gene
Name: adrenergic receptor, alpha 2a
Synonyms: alpha2A-AR, expressed sequence AW122659, RG20, alpha2A-adrenergic receptor, Adra-2, Adra-2a, RATRG20, alpha(2A)AR, adrenergic receptor, alpha 2, CA2-47, AW122659, alpha2A
Source: MGI:87934
Biotype: protein coding gene
OPRM1
(Homo sapiens)Gene
Name: opioid receptor mu 1
Synonyms: M-OR-1, mu-type opioid receptor, MOR1, mu opioid receptor splice variant hMOR-1Z, LMOR, micro opioid receptor isoform hMOR-1A2, mu opioid receptor splice variant hMOR-1Y2, mu opioid receptor splice variant hMOR-1S, mu opioid receptor splice variant hMOR-1Y3, MOP, MOR, mu opiate receptor, KIAA0403, opioid receptor, mu 1, hMOP, OPRM, mu opioid receptor hMOR-1a, mu opioid receptor splice variant hMOR-1b
Source: HGNC:8156
Biotype: protein coding gene
PTPN11
(Homo sapiens)Gene
Name: protein tyrosine phosphatase non-receptor type 11
Synonyms: JMML, protein-tyrosine phosphatase 1D, CFC, protein-tyrosine phosphatase 2C, SH2 domain-containing protein tyrosine phosphatase 2, protein tyrosine phosphatase-2, NS1, METCDS, BPTP3, SHP2, PTP2C, protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), PTP-2C, tyrosine-protein phosphatase non-receptor type 11, MGC14433, PTP-1D, SH-PTP3, SH-PTP2
Source: HGNC:9644
Biotype: protein coding gene
ADRA2C
(Homo sapiens)Gene
Name: adrenoceptor alpha 2C
Synonyms: alpha-2C adrenoreceptor, adrenergic receptor, alpha 2c, adrenergic, alpha-2C-, receptor, ADRARL2, ADRA2L2, alpha-2CAR, alpha-2 adrenergic receptor subtype C4, alpha-2C adrenergic receptor, alpha2-AR-C4, alpha-2C adrenoceptor, ALPHA2CAR, ADRA2RL2, alpha-2C-adrenergic receptor
Source: HGNC:283
Biotype: protein coding gene
Ptpn11
(Mus musculus)Gene
Name: protein tyrosine phosphatase, non-receptor type 11
Synonyms: Shp2, PTP1D, PTP2C, SHP-2, SH2 domain-containing protein tyrosine phosphatase-2, expressed sequence AW536184, AW536184, Syp, RIKEN cDNA 2700084A17 gene, 2700084A17Rik, SH-PTP2
Source: MGI:99511
Biotype: protein coding gene
Oprm1
(Rattus norvegicus)Gene
Name: opioid receptor, mu 1
Synonyms: opioid receptor B, mu opioid receptor splice variant rMOR-1Z, MUOR1, mu-type opioid receptor, M-OR-1, MORA, MOR-1, mu opioid receptor splice variant rMOR-1S, mu opioid receptor, Oprm, Oprrm1
Source: RGD:3234
Biotype: protein coding gene
FFAR2
(Homo sapiens)Gene
Name: free fatty acid receptor 2
Synonyms: fatty acid receptor 2, free fatty acid activated receptor 2, GPR43, G-protein coupled receptor 43, G protein-coupled receptor 43, FFA2R
Source: HGNC:4501
Biotype: protein coding gene
MTNR1B
(Homo sapiens)Gene
Name: melatonin receptor 1B
Synonyms: MEL-1B-R, mel1b receptor, melatonin receptor type 1B, melatonin receptor 1B variant b, melatonin receptor MEL1B, MT2, FGQTL2
Source: HGNC:7464
Biotype: protein coding gene
Pde4c
(Mus musculus)Gene
Name: phosphodiesterase 4C, cAMP specific
Synonyms: E130301F19Rik, Dpde1, dunce, MGC:31320, RIKEN cDNA E130301F19 gene
Source: MGI:99556
Biotype: protein coding gene
Acvr1c
(Mus musculus)Gene
Name: activin A receptor, type IC
Synonyms: habrec1, Alk7, ALK7, Alk-7
Source: MGI:2661081
Biotype: protein coding gene
Il1b
(Rattus norvegicus)Gene
Name: interleukin 1 beta
Synonyms: interleukin-1 beta, IL-1F2, IL-1 beta
Source: RGD:2891
Biotype: protein coding gene
Foxo1
(Mus musculus)Gene
Name: forkhead box O1
Synonyms: Foxo1a, expressed sequence AI876417, AI876417, Afxh, Fkhr, Fkhr1, FKHR
Source: MGI:1890077
Biotype: protein coding gene
Ins1
(Mus musculus)Gene
Name: insulin I
Synonyms: Ins2-rs1, insulin I or insulin pseudogene, insulin 2, related sequence 1, Ins-1
Source: MGI:96572
Biotype: protein coding gene
F2r
(Mus musculus)Gene
Name: coagulation factor II thrombin receptor
Synonyms: coagulation factor II, receptor, expressed sequence AI482343, ThrR, protease-activated receptor 1, Par1, AI482343, TRGPC, Cf2r, thrombin receptor
Source: MGI:101802
Biotype: protein coding gene
Neo1
(Mus musculus)Gene
Name: neogenin
Synonyms: Igdcc2, RIKEN cDNA D930014N22 gene, RIKEN cDNA 2610028H22 gene, 2610028H22Rik, D930014N22Rik, expressed sequence AI327052, AI327052
Source: MGI:1097159
Biotype: protein coding gene
Gnao1
(Mus musculus)Gene
Name: guanine nucleotide binding protein, alpha O
Synonyms: Gnao, Hg1g, GO, AW050213, alphaO, Go alpha, Galphao, RATBPGTPC, expressed sequence AW050213
Source: MGI:95775
Biotype: protein coding gene
Map4k4
(Mus musculus)Gene
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: 9430080K19Rik, expressed sequence AU045934, NCK interacting kinase, Nik, AU045934, AU043147, expressed sequence AW046177, AW046177, RIKEN cDNA 9430080K19 gene, expressed sequence AU043147
Source: MGI:1349394
Biotype: protein coding gene
aak-2
(Caenorhabditis elegans)Gene
Name: AMP-Activated Kinase 2
Synonyms: T01C8.1, AMPK, CELE_T01C8.1
Source: WB:WBGene00020142
Biotype: protein coding gene
MAP4K4
(Homo sapiens)Gene
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: FLJ20373, MEKKK 4, HEL-S-31, nck-interacting kinase, FLJ10410, MEK kinase kinase 4, epididymis secretory protein Li 31, HGK, Ste20 group protein kinase HGK, NIK, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, MEKKK4, KIAA0687, FLH21957, FLJ90111, MAPK/ERK kinase kinase kinase 4, HPK/GCK-like kinase HGK
Source: HGNC:6866
Biotype: protein coding gene
Rptor
(Mus musculus)Gene
Name: regulatory associated protein of MTOR, complex 1
Synonyms: Rap, RGD1311784, raptor, 4932417H02Rik, mKIAA1303, RIKEN cDNA 4932417H02 gene
Source: MGI:1921620
Biotype: protein coding gene
npr-1
(Caenorhabditis elegans)Gene
Name: NeuroPeptide Receptor family 1
Synonyms: bor-1, CELE_C39E6.6, C39E6.6
Source: WB:WBGene00003807
Biotype: protein coding gene
Chga
(Mus musculus)Gene
Name: chromogranin A
Synonyms: ChrA
Source: MGI:88394
Biotype: protein coding gene
Mup3
(Mus musculus)Gene
Name: major urinary protein 3
Synonyms: Mup, RGD1566134, AABR07048463.1, Mup4l2, Mup-3, PGCL6
Source: MGI:97235
Biotype: protein coding gene
SERGEF
(Homo sapiens)Gene
Name: secretion regulating guanine nucleotide exchange factor
Synonyms: deafness locus associated putative guanine nucleotide exchange factor, guanine nucleotide exchange factor-related protein, DELGEF, Gnefr, secretion-regulating guanine nucleotide exchange factor, deafness locus-associated putative guanine nucleotide exchange factor
Source: HGNC:17499
Biotype: protein coding gene
Pde3b
(Mus musculus)Gene
Name: phosphodiesterase 3B, cGMP-inhibited
Synonyms: 9830102A01Rik, AI847709, RIKEN cDNA 9830102A01 gene, CGI PDE, expressed sequence AI847709, RcGIPl
Source: MGI:1333863
Biotype: protein coding gene