Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: limb morphogenesis
Sox9
(Rattus norvegicus)Gene
Name: SRY-box transcription factor 9
Synonyms: SRY-box containing gene 9, LOC363699, SRY (sex determining region Y)-box 9, SRY box 9, transcription factor SOX-9, LOC100361122, SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal), SRY
Source: RGD:620474
Biotype: protein coding gene
Msx1
(Mus musculus)Gene
Name: msh homeobox 1
Synonyms: Hox-7, msh, AA675338, expressed sequence AI324650, homeo box-7 cluster, msh-like, Hox7, AI324650, expressed sequence AA675338, muscle-segment homeobox, Hox7.1
Source: MGI:97168
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Bmp4
(Mus musculus)Gene
Name: bone morphogenetic protein 4
Synonyms: Bmp2b, bone morphogenetic protein 2b, BOMPR4A, Bmp2b-1, Bmp-4, bone morphogenetic protein 2b 1, Bmp2b1
Source: MGI:88180
Biotype: protein coding gene
Sema3c
(Mus musculus)Gene
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Synonyms: semaphorin E, 1110036B02Rik, RIKEN cDNA 1110036B02 gene, Semae
Source: MGI:107557
Biotype: protein coding gene
BMP4
(Homo sapiens)Gene
Name: bone morphogenetic protein 4
Synonyms: MCOPS6, bone morphogenetic protein 2B, bone morphogenetic protein 4 preproprotein, BMP2B, OFC11, BMP-2B, BMP-4, ZYME, BMP2B1
Source: HGNC:1071
Biotype: protein coding gene
ALX3
(Homo sapiens)Gene
Name: ALX homeobox 3
Synonyms: homeobox protein aristaless-like 3, FND1, MGC138212, aristaless-like homeobox 3, frontonasal dysplasia, proline-rich transcription factor ALX3, FND, MGC141988
Source: HGNC:449
Biotype: protein coding gene
PSEN1
(Homo sapiens)Gene
Name: presenilin 1
Synonyms: AD3, presenilin-1 isoform I-467, PS-1, FAD, ACNINV3, familial Alzheimer Disease, CMD1U, presenilin 1 (Alzheimer disease 3), presenilin-1, PSNL1, S182, PS1
Source: HGNC:9508
Biotype: protein coding gene
Fgf8
(Mus musculus)Gene
Name: fibroblast growth factor 8
Synonyms: androgen induced growth factor, Fgf6c, Aigf, Fgf-8
Source: MGI:99604
Biotype: protein coding gene
Ctnnb1
(Mus musculus)Gene
Name: catenin beta 1
Synonyms: beta-catenin, beta catenin, Catnb, batface, catenin beta, catenin (cadherin associated protein), beta 1, Bfc
Source: MGI:88276
Biotype: protein coding gene
HOTAIR
(Homo sapiens)Gene
Name: HOX transcript antisense RNA
Synonyms: HOXC11-AS1, HOXC-AS4, HOXAS, NCRNA00072, FLJ41747
Source: HGNC:33510
Biotype: ncRNA gene
Bax
(Mus musculus)Gene
Name: BCL2-associated X protein
Synonyms: Not Available
Source: MGI:99702
Biotype: protein coding gene
FGFR2
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 2
Synonyms: FLJ98662, fibroblast growth factor receptor 2 Ksam IV secreted isoform, K-SAM, KGFR, FGFR-2, CFD1, keratinocyte growth factor receptor, BBDS, BEK fibroblast growth factor receptor, ECT1, bacteria-expressed kinase, TK25, CD332, FGF receptor, fibroblast growth factor receptor 2 isoform IgIIIc isoform, JWS, fibroblast growth factor receptor 2 isoform IgIIIb isoform, BEK, hydroxyaryl-protein kinase, BFR-1, protein tyrosine kinase, receptor like 14, CEK3, soluble FGFR4 variant 4, TK14, FGFR2-AHCYL1 fusion kinase protein, fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome)
Source: HGNC:3689
Biotype: protein coding gene
SHH
(Homo sapiens)Gene
Name: sonic hedgehog signaling molecule
Synonyms: HLP3, HPE3, sonic hedgehog, TPT, ShhNC, sonic hedgehog homolog, HHG1, MCOPCB5, SMMCI, sonic hedgehog protein, shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, TPTPS
Source: HGNC:10848
Biotype: protein coding gene
ATP7A
(Homo sapiens)Gene
Name: ATPase copper transporting alpha
Synonyms: ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome), DSMAX, copper pump 1, Cu++-transporting P-type ATPase, Menkes disease-associated protein, SMAX3, FLJ17790, copper-transporting ATPase 1, MNK, ATPase, Cu++ transporting, alpha polypeptide, MK, HMNX
Source: HGNC:869
Biotype: protein coding gene
SMAD4
(Homo sapiens)Gene
Name: SMAD family member 4
Synonyms: hSMAD4, deleted in pancreatic carcinoma locus 4, MADH4, MAD homolog 4, mothers against decapentaplegic homolog 4, SMAD 4, mothers against DPP homolog 4, deletion target in pancreatic carcinoma 4, JIP, MAD, mothers against decapentaplegic homolog 4, mothers against decapentaplegic, Drosophila, homolog of, 4, smad, mothers against dpp homolog 4 (drosophila), MYHRS, DPC4, SMAD, mothers against DPP homolog 4
Source: HGNC:6770
Biotype: protein coding gene
NOTCH1
(Homo sapiens)Gene
Name: notch receptor 1
Synonyms: notch 1, translocation-associated notch protein TAN-1, TAN1, neurogenic locus notch homolog protein 1, notch gene homolog 1, (drosophila), hN1, Notch homolog 1, translocation-associated, AOVD1, AOS5
Source: HGNC:7881
Biotype: protein coding gene
GNAS
(Homo sapiens)Gene
Name: GNAS complex locus
Synonyms: PHP1B, ALEX, SgVI, PHP1A, PHP1C, G protein subunit alpha S, adenylate cyclase-stimulating G alpha protein, PITA3, neuroendocrine secretory protein, guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, AHO, dJ806M20.3.3, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1, GSA, GPSA, guanine nucleotide regulatory protein, extra large alphas protein, MGC33735, alternative gene product encoded by XL-exon, C20orf45, GSP, secretogranin VI, POH, dJ309F20.1.1, NESP, GNAS1, AIMAH1, SCG6, NESP55
Source: HGNC:4392
Biotype: protein coding gene
SOX9
(Homo sapiens)Gene
Name: SRY-box transcription factor 9
Synonyms: SRXY10, SRY box 9, transcription factor SOX-9, CMPD1, CMD1, SRA1, SRXX2, SRY (sex determining region Y)-box9, SRY-related HMG-box, gene 9, SRY (sex-determining region Y)-box 9 protein, SRY-box 9
Source: HGNC:11204
Biotype: protein coding gene
FGF8
(Homo sapiens)Gene
Name: fibroblast growth factor 8
Synonyms: KAL6, androgen-induced growth factor, fibroblast growth factor 8 (androgen-induced), HBGF-8, HH6, heparin-binding growth factor 8, AIGF, MGC149376, FGF-8
Source: HGNC:3686
Biotype: protein coding gene
CTNNB1
(Homo sapiens)Gene
Name: catenin beta 1
Synonyms: beta-catenin, catenin (cadherin-associated protein), beta 1, MRD19, EVR7, catenin (cadherin-associated protein), beta 1, 88kDa, DKFZp686D02253, CTNNB, armadillo, FLJ37923, catenin beta-1, NEDSDV, FLJ25606
Source: HGNC:2514
Biotype: protein coding gene
Tbx3
(Mus musculus)Gene
Name: T-box 3
Synonyms: DNA segment, Chr 5, ERATO Doi 189, expressed, D5Ertd189e
Source: MGI:98495
Biotype: protein coding gene
Hoxd11
(Mus musculus)Gene
Name: homeobox D11
Synonyms: E230017H14Rik, homeo box-4 cluster, gene 6, Hox-5.4, homeo box-5 cluster, gene 4, Hox-5.5, Hox-4.6, RIKEN cDNA E230017H14 gene
Source: MGI:96203
Biotype: protein coding gene
Gli3
(Mus musculus)Gene
Name: GLI-Kruppel family member GLI3
Synonyms: add, anterior digit pattern deformity, expressed sequence AI854843, extra toes, brachyphalangy, polydactyly Nagoya, AU023367, expressed sequence AU023367, Pdn, Bph, Xt, AI854843
Source: MGI:95729
Biotype: protein coding gene
IDUA
(Homo sapiens)Gene
Name: alpha-L-iduronidase
Synonyms: MPS1, iduronidase, alpha-L-, iduronidase alpha-L-, IDA, MPSI, mucopolysaccharidosis type I
Source: HGNC:5391
Biotype: protein coding gene
Fgfr2
(Mus musculus)Gene
Name: fibroblast growth factor receptor 2
Synonyms: Fgfr7, AU043015, KGFRTr, seminal vesicle shape, fibroblast growth factor receptor 7, Bek, KGFR, AW556123, svs, Fgfr2b, bacterially expressed kinase, Fgfr-7, Fgfr-2, expressed sequence AW556123, expressed sequence AU043015
Source: MGI:95523
Biotype: protein coding gene
Pitx2
(Mus musculus)Gene
Name: paired-like homeodomain transcription factor 2
Synonyms: RIKEN cDNA 9430085M16 gene, Pitx-2, solurshin, Pitx2b, Pitx2a, Brx1b, Otlx2, Pitx2c, Brx1a, Munc30, Brx1, Rieger syndrome protein, Ptx2, 9430085M16Rik, Rieg
Source: MGI:109340
Biotype: protein coding gene
Tbx4
(Mus musculus)Gene
Name: T-box 4
Synonyms: Not Available
Source: MGI:102556
Biotype: protein coding gene
Aff3
(Mus musculus)Gene
Name: AF4/FMR2 family, member 3
Synonyms: lymphoid nuclear protein related to AF4, LAF-4, Laf4, 3222402O04Rik, RIKEN cDNA 3222402O04 gene
Source: MGI:106927
Biotype: protein coding gene
Tbx5
(Mus musculus)Gene
Name: T-box 5
Synonyms: Not Available
Source: MGI:102541
Biotype: protein coding gene
Lef1
(Mus musculus)Gene
Name: lymphoid enhancer binding factor 1
Synonyms: expressed sequence AI451430, AI451430, lymphoid enhancer factor 1, Lef-1
Source: MGI:96770
Biotype: protein coding gene
Sall3
(Mus musculus)Gene
Name: spalt like transcription factor 3
Synonyms: spalt homolog (Drosophila), Salt, Msal-1, B130022O04Rik, Msal, Spalt, RIKEN cDNA B130022O04 gene, spart homolog (Drosophila)
Source: MGI:109295
Biotype: protein coding gene
MECOM
(Homo sapiens)Gene
Name: MDS1 and EVI1 complex locus
Synonyms: zinc finger protein Evi1, AML1-EVI-1, PRDM3, ecotropic virus integration site 1 protein homolog, AML1-EVI-1 fusion protein, PR domain 3, MGC97004, myelodysplasia syndrome-associated protein 1, RUSAT2, oncogene EVI1, histone-lysine N-methyltransferase MECOM, MDS1, MDS1-EVI1, ecotropic viral integration site 1, EVI1, KMT8E, myelodysplasia syndrome 1, myelodysplasia syndrome 1 protein, MDS1 and EVI1 complex locus protein EVI1, MDS1 and EVI1 complex locus protein MDS1, MGC163392
Source: HGNC:3498
Biotype: protein coding gene
Grem1
(Mus musculus)Gene
Name: gremlin 1, DAN family BMP antagonist
Synonyms: cysteine knot superfamily 1, BMP antagonist 1, Grem, gremlin, down-regulated in v-mos-transformed cells, limb deformity, ld, drm, Drm, Cktsf1b1
Source: MGI:1344337
Biotype: protein coding gene
Sall1
(Mus musculus)Gene
Name: spalt like transcription factor 1
Synonyms: Msal-3
Source: MGI:1889585
Biotype: protein coding gene
MAP3K20
(Homo sapiens)Gene
Name: mitogen-activated protein kinase kinase kinase 20
Synonyms: leucine zipper- and sterile alpha motif-containing kinase, mitogen-activated protein kinase kinase kinase MLT, ZAK, MRK, protein kinase, mlklak, SFMMP, MLK7, human cervical cancer suppressor gene 4 protein, MLT, MLK-related kinase, mixed lineage kinase 7, sterile alpha motif and leucine zipper containing kinase AZK, ZAK1 homolog, leucine zipper and sterile-alpha motif kinase, mixed lineage kinase with a leucine zipper and a sterile alpha motif, mixed lineage kinase-related kinase MRK-beta, MLK-like mitogen-activated protein triple kinase, CNM6, AZK, MLTK, MLTKalpha, pk, MLTKbeta, HCCS-4, sterile alpha motif- and leucine zipper-containing kinase AZK, cervical cancer suppressor gene 4 protein
Source: HGNC:17797
Biotype: protein coding gene
Psen1
(Mus musculus)Gene
Name: presenilin 1
Synonyms: alzheimer disease 3 homolog, PS-1, Ad3h, S182, presenilin-1, PS1
Source: MGI:1202717
Biotype: protein coding gene
Smarca4
(Mus musculus)Gene
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms: brahma related gene 1, brg-1, Brg1, b2b508.1Clo, b2b692Clo, SW1/SNF, Mutant line 692, Mutant line 508, subline 1, SNF2beta
Source: MGI:88192
Biotype: protein coding gene
Zbtb16
(Mus musculus)Gene
Name: zinc finger and BTB domain containing 16
Synonyms: Znf145, zinc finger protein 145, Green's luxoid, AI467657, expressed sequence AI467657, lu, Zfp145, Lx, PLZF, Plzf, luxoid
Source: MGI:103222
Biotype: protein coding gene
Psen1
(Rattus norvegicus)Gene
Name: presenilin 1
Synonyms: PS-1, presenilin-1
Source: RGD:3425
Biotype: protein coding gene
CACNA1C
(Homo sapiens)Gene
Name: calcium voltage-gated channel subunit alpha1 C
Synonyms: calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit, CACH2, voltage-dependent L-type Ca2+ channel alpha 1 subunit, voltage-dependent L-type calcium channel subunit alpha-1C, voltage-gated calcium channel alpha subunit Cav1.2, CACN2, CACNA1C intronic transcript 2, calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, LQT8, voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*, CCHL1A1, CaV1.2, MGC120730, calcium channel, L type, alpha 1 polypeptide, isoform 1, cardic muscle, DHPR, alpha-1 subunit, calcium channel, voltage-dependent, alpha 1c subunit, NEDHLSS, voltage-gated calcium channel subunit alpha Cav1.2, TS. LQT8, CACNL1A1, CACNA1C-IT2, CACNA1C intronic transcript 2 (non-protein coding), calcium channel, voltage-dependent, L type, alpha 1C subunit, TS
Source: HGNC:1390
Biotype: protein coding gene
Med1
(Mus musculus)Gene
Name: mediator complex subunit 1
Synonyms: CRSP210, peroxisome proliferator activated receptor binding protein, TRAP220, RGD1559552, Pparbp, l11Jus15, DRIP205, AI480703, expressed sequence AI480703, TRAP 220, PBP
Source: MGI:1100846
Biotype: protein coding gene
Fgf4
(Mus musculus)Gene
Name: fibroblast growth factor 4
Synonyms: heparin secretory transforming protein 1, Fgf7a, Hstf-1, Fgf-4, Fgfk, Hst, Hst1, kFGF
Source: MGI:95518
Biotype: protein coding gene
Pitx1
(Mus musculus)Gene
Name: paired-like homeodomain transcription factor 1
Synonyms: Bft, pituitary OTX-related factor, Potx, Ptx1, P-OTX
Source: MGI:107374
Biotype: protein coding gene
Hoxd10
(Mus musculus)Gene
Name: homeobox D10
Synonyms: homeo box-4 cluster, gene 5, Hox-5.3, Hox-4.5, expressed sequence AI385591, expressed sequence AI874987, AI874987, homeo box-5 cluster, gene 3, AI385591
Source: MGI:96202
Biotype: protein coding gene
GDF5
(Homo sapiens)Gene
Name: growth differentiation factor 5
Synonyms: SYM1B, cartilage-derived morphogenetic protein 1, lipopolysaccharide-associated protein 4, radotermin, growth/differentiation factor 5, BMP-14, BMP14, LAP-4, BDA1C, OS5, cartilage-derived morphogenetic protein-1, GDF-5, LAP4, DUPANS, bone morphogenetic protein 14, LPS-associated protein 4, SYNS2, CDMP1, CDMP-1
Source: HGNC:4220
Biotype: protein coding gene
Lrp6
(Mus musculus)Gene
Name: low density lipoprotein receptor-related protein 6
Synonyms: Gw, Cd, skeletal/axial 26, gwazi, crooked, ska26, skax26, ska
Source: MGI:1298218
Biotype: protein coding gene
Ptch1
(Mus musculus)Gene
Name: patched 1
Synonyms: Ptch2, wig, Ptc1, Patched 1, RIKEN cDNA A230106A15 gene, mes, wiggable, mesenchymal dysplasia, A230106A15Rik, Ptc, Ptch
Source: MGI:105373
Biotype: protein coding gene
Hoxd12
(Mus musculus)Gene
Name: homeobox D12
Synonyms: homeo box-4 cluster, gene 7, Hox-5.6, Hox-4.7, homeo box-5 cluster, gene 6
Source: MGI:96204
Biotype: protein coding gene
Gdf5
(Mus musculus)Gene
Name: growth differentiation factor 5
Synonyms: brp, cartilage-derived morphogenetic protein-1, Cdmp1, brachypodism, bp, brachypod Japan, CDMP-1
Source: MGI:95688
Biotype: protein coding gene