Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: negative regulation of secretion by cell Molecular Function: signaling receptor binding
BRAF
(Homo sapiens)Gene
Name: B-Raf proto-oncogene, serine/threonine kinase
Synonyms: serine/threonine-protein kinase B-raf, RAFB1, B-Raf serine/threonine-protein, B-RAF1, v-raf murine sarcoma viral oncogene homolog B1, v-raf murine sarcoma viral oncogene homolog B, p94, B-Raf proto-oncogene serine/threonine-protein kinase (p94), proto-oncogene B-Raf, MGC138284, MGC126806, NS7, B-raf, BRAF1, FLJ95109, 94 kDa B-raf protein, BRAF-1, murine sarcoma viral (v-raf) oncogene homolog B1
Source: HGNC:1097
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
Braf
(Mus musculus)Gene
Name: Braf transforming gene
Synonyms: expressed sequence C87398, expressed sequence AA120551, expressed sequence AA387315, Braf-2, Braf2, AA387315, DNA segment, Chr 6, ERATO Doi 631, expressed, RIKEN cDNA 9930012E13 gene, C87398, AA120551, Braf transforming gene 2, D6Ertd631e, expressed sequence AA473386, AA473386, 9930012E13Rik
Source: MGI:88190
Biotype: protein coding gene
C9orf72
(Homo sapiens)Gene
Name: C9orf72-SMCR8 complex subunit
Synonyms: chromosome 9 open reading frame 72, FTDALS, DENNL72, MGC23980, hypothetical protein LOC203228, FTDALS1, uncharacterized protein C9orf72, guanine nucleotide exchange C9orf72, DENND9, RP11-27J8.2, ALSFTD, guanine nucleotide exchange factor C9orf72
Source: HGNC:28337
Biotype: protein coding gene
Pou5f1
(Mus musculus)Gene
Name: POU domain, class 5, transcription factor 1
Synonyms: Oct-4, Oct-3, Otf-4, Otf-3, octamer binding transcription factor 4, octamer binding transcription factor 3, Oct3/4, Oct4, Otf4, Otf3, Oct-3/4, Otf3-rs7, Otf3g, octamer binding transcription factor 3 related sequence 7
Source: MGI:101893
Biotype: protein coding gene
ACSL4
(Homo sapiens)Gene
Name: acyl-CoA synthetase long chain family member 4
Synonyms: LACS4, lignoceroyl-CoA synthase, FACL4, mental retardation, X-linked 63, long-chain fatty-acid-Coenzyme A ligase 4, acyl-CoA synthetase long-chain family member 4, MRX63, mental retardation, X-linked 68, long-chain acyl-CoA synthetase 4, MRX68, XLID63, arachidonate--CoA ligase, LACS 4, fatty-acid-Coenzyme A ligase, long-chain 4, ACS4, long-chain-fatty-acid--CoA ligase 4, acyl-CoA synthetase 4
Source: HGNC:3571
Biotype: protein coding gene
NF1
(Homo sapiens)Gene
Name: neurofibromin 1
Synonyms: truncated neurofibromin 1, neurofibromin, WSS, DKFZp686J1293, FLJ21220, neurofibromatosis-related protein NF-1, neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease), NFNS, VRNF, neurofibromatosis 1
Source: HGNC:7765
Biotype: protein coding gene
FMR1
(Homo sapiens)Gene
Name: fragile X messenger ribonucleoprotein 1
Synonyms: fragile x mental retardation syndrome 1 homolog, fragile X mental retardation protein 1, fragile X mental retardation 1, FMRP, POF, fragile site, folic acid type, rare, fra(X)(q27.3), (macroorchidism, mental retardation), premature ovarian failure 1, truncated FMRP, POF1, FMR-1, FMRP translational regulator 1, MGC87458, fragile X mental retardation 1 protein, synaptic functional regulator FMR1, FRAXA
Source: HGNC:3775
Biotype: protein coding gene
PPARG
(Homo sapiens)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: peroxisome proliferator-activated receptor-gamma splicing, peroxisome proliferator activated receptor, gamma, GLM1, PPARgamma, NR1C3, PPAR gamma, PPAR-gamma, PPARG1, peroxisome proliferator-activated receptor gamma 1, PPARG2, peroxisome proliferator-activated receptor-gamma 5, CIMT1, PPARG5, peroxisome proliferator-activated nuclear receptor gamma variant 1, peroxisome proliferator-activated receptor gamma, nuclear receptor subfamily 1 group C member 3
Source: HGNC:9236
Biotype: protein coding gene
Pparg
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: Nr1c3, PPARgamma2, Ppar-gamma2, PPARgamma, PPAR-gamma
Source: MGI:97747
Biotype: protein coding gene
Sirt1
(Mus musculus)Gene
Name: sirtuin 1
Synonyms: Sir2, expressed sequence AA673258, AA673258, Sir2alpha
Source: MGI:2135607
Biotype: protein coding gene
Snca
(Mus musculus)Gene
Name: synuclein, alpha
Synonyms: alpha-Syn, alphaSYN, alpha-synuclein
Source: MGI:1277151
Biotype: protein coding gene
Bcr
(Mus musculus)Gene
Name: BCR activator of RhoGEF and GTPase
Synonyms: 5133400C09Rik, RIKEN cDNA 5133400C09 gene, AI853148, expressed sequence AI853148, mKIAA3017, expressed sequence AI561783, breakpoint cluster region, AI561783
Source: MGI:88141
Biotype: protein coding gene
InR
(Drosophila melanogaster)Gene
Name: Insulin-like receptor
Synonyms: insulin-like receptor tyrosine kinase, Insulin-like Receptor, l(3)93Dj, dINSR, dIR, dInsR, dir, Igf-1 receptor, lnR, Insulin Receptor, er10, Inr-beta, dinr, DInr, IR, Insulin, insulin receptor homologue, DIRbeta, insulin receptor homolog, lethal(3)93Dj, Inr-alpha, dinR, dINR, dInr, RTK, DInR, INR, Inr, inR, insulin-like receptor, Drosophila Insulin Receptor, INS, Igfr1, insulin/IGF receptor, Insulin-receptor, DIRH, Insulin receptor, insulin/insulin-like growth factor receptor, l(3)05545, Drosophila insulin receptor, 18402, sprout, InsR, dInR, DILR, DIR, inr, Dir-b, l(3)er10, Dir-a, DIHR, dIRH, insulin receptor, insulin-receptor, CG18402
Source: FB:FBgn0283499
Biotype: protein coding gene
Ppp3ca
(Mus musculus)Gene
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Synonyms: AW413465, RIKEN cDNA 2900074D19 gene, AI841391, CN, calcineurin, Calna1, expressed sequence AW413465, 2900074D19Rik, CnA, expressed sequence AI841391, calcineurin, alpha subunit, Calna, PP2BA alpha, PP2B alpha 1, Caln
Source: MGI:107164
Biotype: protein coding gene
Fmr1
(Mus musculus)Gene
Name: fragile X messenger ribonucleoprotein 1
Synonyms: Fmr-1, fragile X mental retardation 1, FMRP, fragile X mental retardation syndrome 1
Source: MGI:95564
Biotype: protein coding gene
FOXO1
(Homo sapiens)Gene
Name: forkhead box O1
Synonyms: forkhead box protein O1, forkhead, Drosophila, homolog of, in rhabdomyosarcoma, FOXO1A, forkhead homolog in rhabdomyosarcoma, forkhead in rhabdomyosarcoma, FKH1, forkhead box protein O1A, FKHR
Source: HGNC:3819
Biotype: protein coding gene
BCR
(Homo sapiens)Gene
Name: BCR activator of RhoGEF and GTPase
Synonyms: ALL, D22S662, CML, PHL, renal carcinoma antigen NY-REN-26, FGFR1/BCR chimera protein, FLJ16453, BCR/FGFR1 chimera protein, D22S11, breakpoint cluster region, BCR1
Source: HGNC:1014
Biotype: protein coding gene
Ppp1r9a
(Mus musculus)Gene
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: Neb1, 4930518N04Rik, RIKEN cDNA 2810430P21 gene, expressed sequence BB181831, p180, neurabin-I, Neurabin I, mKIAA1222, A230094E16Rik, PP1bp175, RIKEN cDNA A230094E16 gene, RIKEN cDNA 4930518N04 gene, 2810430P21Rik, BB181831, NRB
Source: MGI:2442401
Biotype: protein coding gene
Kcnj11
(Mus musculus)Gene
Name: potassium inwardly rectifying channel, subfamily J, member 11
Synonyms: Kir6.2, expressed sequence AI842722, expressed sequence AW491124, AW491124, AI842722
Source: MGI:107501
Biotype: protein coding gene
Prkg1
(Mus musculus)Gene
Name: protein kinase, cGMP-dependent, type I
Synonyms: protein kinase, cGMP-dependent, type I beta, Prkg1b, expressed sequence AW125416, Prkgr1b, AW125416, protein kinase, cGMP dependent, regulatory type I beta
Source: MGI:108174
Biotype: protein coding gene
Ffar3
(Mus musculus)Gene
Name: free fatty acid receptor 3
Synonyms: Gm478, gene model 478, (NCBI), Gpr41, LOC233080, G protein-coupled receptor 41
Source: MGI:2685324
Biotype: protein coding gene
Kcnj6
(Mus musculus)Gene
Name: potassium inwardly-rectifying channel, subfamily J, member 6
Synonyms: KCNJ7, Kir3.2, weaver, GIRK2, wv
Source: MGI:104781
Biotype: protein coding gene
Nos1
(Mus musculus)Gene
Name: nitric oxide synthase 1, neuronal
Synonyms: NO, nitric oxide synthase 1 (macrophage), nNOS, RIKEN cDNA 2310005C01 gene, Nos-1, 2310005C01Rik, bNOS
Source: MGI:97360
Biotype: protein coding gene
Cnr1
(Mus musculus)Gene
Name: cannabinoid receptor 1
Synonyms: SKR6R, CB1, CB-R, CB1R
Source: MGI:104615
Biotype: protein coding gene
Hadh
(Mus musculus)Gene
Name: hydroxyacyl-Coenzyme A dehydrogenase
Synonyms: AW742602, expressed sequence AW742602, expressed sequence AA409008, hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase, hydroxylacyl-Coenzyme A dehydrogenase, AA409008, Schad, L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain, expressed sequence AU019341, Hadhsc, AU019341
Source: MGI:96009
Biotype: protein coding gene
NR1H3
(Homo sapiens)Gene
Name: nuclear receptor subfamily 1 group H member 3
Synonyms: LXR-a, nuclear receptor subfamily 1, group H, member 3, oxysterols receptor LXR-alpha, LXRA, RLD-1, CHOP, liver X nuclear receptor alpha variant 1, liver X receptor alpha, TLS/CHOP, liver X receptor, alpha, liver X receptor-alpha
Source: HGNC:7966
Biotype: protein coding gene
RAB7A
(Homo sapiens)Gene
Name: RAB7A, member RAS oncogene family
Synonyms: ras-related protein Rab-7a, RAB7, RAB7, member RAS oncogene family, FLJ20819, PRO2706, Ras-associated protein RAB7, Charcot-Marie-Tooth neuropathy 2B, CMT2B
Source: HGNC:9788
Biotype: protein coding gene
Myo5a
(Mus musculus)Gene
Name: myosin VA
Synonyms: dilute, Dop, d, flailer, Myh12, myosin V, 9630007J19Rik, flr, nmf244, AI661011, flail, expressed sequence AI661011, RIKEN cDNA 9630007J19 gene, Myo5, AI413174, expressed sequence AI413174, Dbv, MVa, MyoVA
Source: MGI:105976
Biotype: protein coding gene
Syt4
(Mus musculus)Gene
Name: synaptotagmin IV
Synonyms: Not Available
Source: MGI:101759
Biotype: protein coding gene
Igfbp3
(Mus musculus)Gene
Name: insulin-like growth factor binding protein 3
Synonyms: AI649005, IGFBP-3, IGF-BP3, expressed sequence AI649005
Source: MGI:96438
Biotype: protein coding gene
Stxbp5l
(Mus musculus)Gene
Name: syntaxin binding protein 5-like
Synonyms: RIKEN cDNA A830015P08 gene, type 2 diabetes mellitus 1, tomosyn-2, t2md1, insulin level locus 1, LLGL4, T2dm1, A830015P08Rik
Source: MGI:2443815
Biotype: protein coding gene
CYP51A1
(Homo sapiens)Gene
Name: cytochrome P450 family 51 subfamily A member 1
Synonyms: cytochrome P450 51A1, CYPL1, lanosterol 14-alpha-demethylase, cytochrome P450-14DM, cytochrome P450LI, lanosterol 14-alpha demethylase, sterol 14-alpha demethylase, CYPLI, CYP51, LDM, CP51, cytochrome P450, family 51, subfamily A, polypeptide 1, cytochrome P45014DM, cytochrome P450, 51 (lanosterol 14-alpha-demethylase), P450-14DM, P450L1
Source: HGNC:2649
Biotype: protein coding gene
rap-1
(Caenorhabditis elegans)Gene
Name: RAP homolog (vertebrate Rap GTPase family) 1
Synonyms: CELE_C27B7.8, C27B7.8, rrp-1
Source: WB:WBGene00004307
Biotype: protein coding gene
Maob
(Rattus norvegicus)Gene
Name: monoamine oxidase B
Synonyms: monoamine oxidase-B, monoamine oxidase type B, MAO-B, amine oxidase [flavin-containing] B
Source: RGD:3041
Biotype: protein coding gene
Tspo
(Mus musculus)Gene
Name: translocator protein
Synonyms: PBR, Tspo1, Bzrp, Ptbzr, MBR, benzodiazepine receptor, peripheral, PTBZR02, RATPTBZR02
Source: MGI:88222
Biotype: protein coding gene
Tnfrsf1a
(Mus musculus)Gene
Name: tumor necrosis factor receptor superfamily, member 1a
Synonyms: TNF-alpha-R1, TNF-R1, TNFalpha-R1, TNFR60, TNF-R55, TNF-alphaR1, TNFRI, TNF receptor alpha chain, TNFR-1, TNFRp55, p55, p55-R, TNF-R-I, Tnfr1, tumor necrosis factor receptor 2, TNFAR, CD120a, tumor necrosis factor receptor 1, Tnfr-2
Source: MGI:1314884
Biotype: protein coding gene
Rap1b
(Mus musculus)Gene
Name: RAS related protein 1b
Synonyms: RIKEN cDNA 2810443E11 gene, 2810443E11Rik
Source: MGI:894315
Biotype: protein coding gene
Map4k4
(Mus musculus)Gene
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: 9430080K19Rik, expressed sequence AU045934, NCK interacting kinase, Nik, AU045934, AU043147, expressed sequence AW046177, AW046177, RIKEN cDNA 9430080K19 gene, expressed sequence AU043147
Source: MGI:1349394
Biotype: protein coding gene
Gck
(Mus musculus)Gene
Name: glucokinase
Synonyms: HK4, Hlb62, Gls006, GLK, hexokinase 4, MODY2, glucose mutant 006, GLUKA, RNGK2, heart, lung and blood, 62
Source: MGI:1270854
Biotype: protein coding gene
Ptgs1
(Mus musculus)Gene
Name: prostaglandin-endoperoxide synthase 1
Synonyms: Cox-1, Cox1, Pghs-1, Cox-3, Cox3, Pghs1, COX1, cyclooxygenase 1
Source: MGI:97797
Biotype: protein coding gene
Hmox1
(Mus musculus)Gene
Name: heme oxygenase 1
Synonyms: DNA segment, Chr 8, Wayne State University 38, expressed, Heox, D8Wsu38e, HEOXG, Hsp32, hemoxygenase, Ho-1, HO-1, HO1, hsp32, Ho1, Hmox
Source: MGI:96163
Biotype: protein coding gene
POU5F1
(Homo sapiens)Gene
Name: POU class 5 homeobox 1
Synonyms: Oct-4, Oct-3, OTF-3, POU domain, class 5, transcription factor 1, MGC22487, Oct3/4, OCT4, octamer-binding protein 3, octamer-binding transcription factor 3, OTF4, OCT3, POU domain class 5 transcription factor 1, OTF3, POU class 5 homeobox 1 transcript variant OCT4B1, octamer-binding transcription factor-3, POU class 5 homeobox 1 transcript variant OCT4B3, POU class 5 homeobox 1 transcript variant OCT4B2, POU class 5 homeobox 1 transcript variant OCT4B5, POU class 5 homeobox 1 transcript variant OCT4B4, POU domain transcription factor OCT4, octamer-binding protein 4, POU-type homeodomain-containing DNA-binding protein, POU classV homeobox 1 variant 2, POU class 5 homeobox 1 transcript variant OCT4B6
Source: HGNC:9221
Biotype: protein coding gene
HMGCR
(Homo sapiens)Gene
Name: 3-hydroxy-3-methylglutaryl-CoA reductase
Synonyms: hydroxymethylglutaryl-CoA reductase, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase, LDLCQ3, HMG-CoA reductase, 3-hydroxy-3-methylglutaryl CoA reductase (NADPH), LGMDR28, MYPLG
Source: HGNC:5006
Biotype: protein coding gene
KCNB1
(Homo sapiens)Gene
Name: potassium voltage-gated channel subfamily B member 1
Synonyms: delayed rectifier potassium channel Kv2.1, h-DRK1 K(+) channel, KV2.1, DRK1, DEE26, delayed rectifier potassium channel 1, potassium channel, voltage gated Shab related subfamily B, member 1, voltage-gated potassium channel subunit Kv2.1, potassium voltage-gated channel, Shab-related subfamily, member 1, h-DRK1, EIEE26, potassium channel protein DRK1
Source: HGNC:6231
Biotype: protein coding gene
Spi1
(Mus musculus)Gene
Name: Spi-1 proto-oncogene
Synonyms: spleen focus forming virus (SFFV) proviral integration oncogene, Tfpu.1, Sfpi-1, Sfpi1, Spi-1, SFFV proviral integration 1, transcription factor PU.1, Dis-1, PU.1, Pu.1, Tcfpu1
Source: MGI:98282
Biotype: protein coding gene
Hmgcr
(Rattus norvegicus)Gene
Name: 3-hydroxy-3-methylglutaryl-CoA reductase
Synonyms: HMG-CoA reductase, 3H3M, 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Source: RGD:2803
Biotype: protein coding gene
ASIC1
(Homo sapiens)Gene
Name: acid sensing ion channel subunit 1
Synonyms: acid-sensing ion channel 1a protein, acid-sensing (proton-gated) ion channel 1, hBNaC2, BNaC2, ASIC1A, Cation channel, amiloride-sensitive, neuronal, 2, acid sensing ion channel 1, brain sodium channel 2, acid sensing (proton gated) ion channel 1, ASIC, ACCN2, amiloride-sensitive cation channel 2, neuronal, acid-sensing ion channel 1, ACCN2 variant 3
Source: HGNC:100
Biotype: protein coding gene
RAP1A
(Homo sapiens)Gene
Name: RAP1A, member of RAS oncogene family
Synonyms: ras-related protein Rap-1A, Ras-related protein Krev-1, SMGP21, KREV-1, RAP1, G-22K, C21KG, GTP-binding protein smg p21A, RAS-related protein RAP1A, KREV1
Source: HGNC:9855
Biotype: protein coding gene
Oprm1
(Rattus norvegicus)Gene
Name: opioid receptor, mu 1
Synonyms: opioid receptor B, mu opioid receptor splice variant rMOR-1Z, MUOR1, mu-type opioid receptor, M-OR-1, MORA, MOR-1, mu opioid receptor splice variant rMOR-1S, mu opioid receptor, Oprm, Oprrm1
Source: RGD:3234
Biotype: protein coding gene