Version: 8.1.0Date: Fri Apr 18 2025
Gene Biological Process: regulation of protein localization Molecular Function: metal ion binding
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
daf-2
(Caenorhabditis elegans)Gene
Name: abnormal DAuer Formation 2
Synonyms: Y55D5A.5, CELE_Y55D5A.5
Source: WB:WBGene00000898
Biotype: protein coding gene
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide, beta-amyloid peptide(1-42), preA4, beta-amyloid peptide(1-40), cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, AD1, alpha-sAPP, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), alzheimer disease amyloid protein, protease nexin-II, amyloid beta A4 protein, CTFgamma, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, Alzheimer disease 2 (APOE*E4-associated, late onset), MGC1571, AD2
Source: HGNC:613
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, Parkinson disease (autosomal dominant, Lewy body) 4, MGC110988, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, synuclein, alpha, alpha-synuclein, isoform NACP140, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, cerebrovascular amyloid peptide, Alzheimer disease amyloid beta protein, protease nexin II, AL024401, RIKEN cDNA E030013M08 gene, expressed sequence AL024401, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
crb
(Drosophila melanogaster)Gene
Name: crumbs
Synonyms: l(3)07207, Crbs, CT19912, 0509/20, Crumbs, CG6383, 1384/04, Crb, CRB, crumb, crumbs, far, fat rhabdomere, l(3)S058104, DmCrb, lethal (3) 07207, l(3)S050920, l(3)j1B5, fat rhabdomeres
Source: FB:FBgn0259685
Biotype: protein coding gene
Ptgs2
(Mus musculus)Gene
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX-2, Cox-2, PHS II, Cox2, Pghs2, cyclooxygenase-2, prostaglandin G/H synthase, COX2, PHS-2, PGHS-2, cyclooxygenase 2, Tis10
Source: MGI:97798
Biotype: protein coding gene
CDH1
(Homo sapiens)Gene
Name: cadherin 1
Synonyms: BCDS1, LCAM, ECAD, calcium-dependent adhesion protein, epithelial, cell-CAM 120/80, CDHE, cadherin 1, E-cadherin (epithelial), CAM 120/80, UVO, uvomorulin, cadherin 1, type 1, E-cadherin (epithelial), E-cadherin 1, cadherin 1, type 1, E-Cadherin, cadherin-1, CD324, epithelial cadherin, Arc-1, truncated cadherin 1 type 1
Source: HGNC:1748
Biotype: protein coding gene
INS
(Homo sapiens)Gene
Name: insulin
Synonyms: proinsulin, IRDN, preproinsulin, IDDM, PNDM4, insulin-dependent diabetes mellitus 2, ILPR, MODY10, insulin isoform U3B, IDDM1, IDDM2
Source: HGNC:6081
Biotype: protein coding gene
Prkn
(Mus musculus)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkinson disease (autosomal recessive, juvenile) 2, parkin, Park2, Parkin, Park
Source: MGI:1355296
Biotype: protein coding gene
Brca1
(Mus musculus)Gene
Name: breast cancer 1, early onset
Synonyms: BRCA-1
Source: MGI:104537
Biotype: protein coding gene
PRKCA
(Homo sapiens)Gene
Name: protein kinase C alpha
Synonyms: AAG6, PKC-A, PKCI+/-, MGC129901, PKC-alpha, PKCalpha, MGC129900, PRKACA, PKCA, protein kinase C alpha type, aging-associated gene 6
Source: HGNC:9393
Biotype: protein coding gene
PPARG
(Homo sapiens)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: peroxisome proliferator-activated receptor-gamma splicing, peroxisome proliferator activated receptor, gamma, GLM1, PPARgamma, NR1C3, PPAR gamma, FPLD3, PPAR-gamma, PPARG1, peroxisome proliferator-activated receptor gamma 1, peroxisome proliferator-activated receptor-gamma 5, PPARG2, PPARG5, CIMT1, peroxisome proliferator-activated nuclear receptor gamma variant 1, peroxisome proliferator-activated receptor gamma, nuclear receptor subfamily 1 group C member 3
Source: HGNC:9236
Biotype: protein coding gene
FBN1
(Homo sapiens)Gene
Name: fibrillin 1
Synonyms: ACMICD, OCTD, fibrillin-1 preproprotein, MFLS, fibrillin 15, asprosin, Weill-Marchesani syndrome, fibrillin-1, ECTOL1, SSKS, MFS1, FBN, MASS, GPHYSD2, WMS, WMS2, SGS
Source: HGNC:3603
Biotype: protein coding gene
Fbn1
(Mus musculus)Gene
Name: fibrillin 1
Synonyms: expressed sequence AI536462, Fib-1, tight skin, AI536462, Tsk
Source: MGI:95489
Biotype: protein coding gene
Pparg
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: PPARgamma2, Nr1c3, Ppar-gamma2, PPARgamma, PPAR-gamma
Source: MGI:97747
Biotype: protein coding gene
F2
(Homo sapiens)Gene
Name: coagulation factor II, thrombin
Synonyms: thrombin factor II, RPRGL2, prothrombin B-chain, PT, THPH1, coagulation factor II, prepro-coagulation factor II, coagulation factor II (thrombin), serine protease, prothrombin
Source: HGNC:3535
Biotype: protein coding gene
Nrxn1
(Mus musculus)Gene
Name: neurexin I
Synonyms: RIKEN cDNA 9330127H16 gene, neurexin I beta, Nrxn1b, RIKEN cDNA A230068P09 gene, RIKEN cDNA 1700062G21 gene, 1700062G21Rik, neurexin I alpha, mKIAA0578, alpha-latrotoxin receptor (calcium-dependent), A230068P09Rik, 9330127H16Rik
Source: MGI:1096391
Biotype: protein coding gene
STK11
(Homo sapiens)Gene
Name: serine/threonine kinase 11
Synonyms: serine/threonine-protein kinase STK11, polarization-related protein LKB1, renal carcinoma antigen NY-REN-19, serine/threonine kinase 11 (peutz-jeghers syndrome), liver kinase B1, serine/threonine-protein kinase 11, PJS, serine/threonine-protein kinase LKB1, hLKB1, LKB1
Source: HGNC:11389
Biotype: protein coding gene
SHH
(Homo sapiens)Gene
Name: sonic hedgehog signaling molecule
Synonyms: HLP3, HPE3, sonic hedgehog, TPT, ShhNC, sonic hedgehog homolog, HHG1, SMMCI, MCOPCB5, sonic hedgehog protein, shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, TPTPS
Source: HGNC:10848
Biotype: protein coding gene
YOD1
(Homo sapiens)Gene
Name: YOD1 deubiquitinase
Synonyms: OTU domain-containing protein 2, OTU domain containing 2, ubiquitin thioesterase OTU1, DUBA8, DUBA-8, YOD1 OTU deubiquinating enzyme 1 homolog ( yeast), DKFZp451J1719, HIN-7, PRO0907, HIV-1-induced protease 7, hsHIN7, RP11-164O23.1, OTUD2
Source: HGNC:25035
Biotype: protein coding gene
PLK1
(Homo sapiens)Gene
Name: polo like kinase 1
Synonyms: polo like kinase, polo-like kinase 1, cell cycle regulated protein kinase, serine/threonine-protein kinase 13, serine/threonine-protein kinase PLK1, PLK-1, STPK13, PLK, polo (Drosophia)-like kinase
Source: HGNC:9077
Biotype: protein coding gene
Sirt1
(Mus musculus)Gene
Name: sirtuin 1
Synonyms: Sir2, Sir2alpha, expressed sequence AA673258, AA673258
Source: MGI:2135607
Biotype: protein coding gene
Itgam
(Mus musculus)Gene
Name: integrin alpha M
Synonyms: complement receptor type 3, macrophage antigen alpha chain (integrin), F730045J24Rik, CR3, lymphocyte antigen 40, Mac-1a, CD11B (p170), Mac-1 alpha, complement component receptor 3 alpha, CD11b/CD18, Mac-1, Ly-40, RIKEN cDNA F730045J24 gene, Cd11b
Source: MGI:96607
Biotype: protein coding gene
Brca1
(Rattus norvegicus)Gene
Name: BRCA1, DNA repair associated
Synonyms: BRCA-1, breast cancer 1, early onset, breast cancer type 1 susceptibility protein homolog, breast cancer 1, RING-type E3 ubiquitin transferase BRCA1
Source: RGD:2218
Biotype: protein coding gene
Itgb1
(Mus musculus)Gene
Name: integrin beta 1 (fibronectin receptor beta)
Synonyms: Gm9863, fibronectin receptor beta (integrin), expressed sequence AA960159, AA409975, 4633401G24Rik, expressed sequence AA409975, beta1 integrin, ENSMUSG00000051907, RIKEN cDNA 4633401G24 gene, CD29, AA960159, Fnrb, predicted gene 9863, predicted gene, ENSMUSG00000051907
Source: MGI:96610
Biotype: protein coding gene
Cacna1d
(Mus musculus)Gene
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: calcium channel, L type, 1A subunit, 8430418G19Rik, Cchl1a2, Cacnl1a2, C79217, calcium channel, L type, 1A sununit, Cav1.3alpha1, Cchl1a, calcium channel, L type, alpha 1 polypeptide, isoform 2 (neuroendocrine), expressed sequence C79217, calcium channel, L type, 1A2 subunit, D-LTCC, RIKEN cDNA 8430418G19 gene
Source: MGI:88293
Biotype: protein coding gene
Snca
(Mus musculus)Gene
Name: synuclein, alpha
Synonyms: alpha-Syn, alphaSYN, alpha-synuclein
Source: MGI:1277151
Biotype: protein coding gene
Dag1
(Mus musculus)Gene
Name: dystroglycan 1
Synonyms: DNA segment, Chr 9, Wayne State University 13, expressed, DG, alpha-dystroglycan, beta-dystroglycan, D9Wsu13e, dystrophin associated glycoprotein 1
Source: MGI:101864
Biotype: protein coding gene
Gli3
(Mus musculus)Gene
Name: GLI-Kruppel family member GLI3
Synonyms: add, anterior digit pattern deformity, expressed sequence AI854843, extra toes, brachyphalangy, polydactyly Nagoya, AU023367, expressed sequence AU023367, Bph, Pdn, Xt, AI854843
Source: MGI:95729
Biotype: protein coding gene
hh
(Drosophila melanogaster)Gene
Name: hedgehog
Synonyms: Hh, HH, l(3)hh, anon-WO0134654.19, l(3)neo56, l(3)neo57, Dmhh, PKC, anon-WO0182946.19, Hedghog, bar-3, Mrt, bar3, Hedgehog, bar, atypical, Mir, bar-on-3, Moonrat, Mirabile, Hg, hg, CG4637
Source: FB:FBgn0004644
Biotype: protein coding gene
Fgg
(Mus musculus)Gene
Name: fibrinogen gamma chain
Synonyms: 3010002H13Rik, AI256424, gamma-fibrinogen, RIKEN cDNA 3010002H13 gene, expressed sequence AI256424
Source: MGI:95526
Biotype: protein coding gene
Glul
(Mus musculus)Gene
Name: glutamate-ammonia ligase
Synonyms: glutamine synthetase, Glns, GS
Source: MGI:95739
Biotype: protein coding gene
Traf6
(Mus musculus)Gene
Name: TNF receptor-associated factor 6
Synonyms: C630032O20Rik, RIKEN cDNA 2310003F17 gene, AI851288, RIKEN cDNA C630032O20 gene, expressed sequence AI851288, 2310003F17Rik
Source: MGI:108072
Biotype: protein coding gene
Trim30a
(Mus musculus)Gene
Name: tripartite motif-containing 30A
Synonyms: Trim30, Rpt-1, tripartite motif-containing 30, regulatory protein, T lymphocyte 1, RGD1566132, Rpt1
Source: MGI:98178
Biotype: protein coding gene
Ppp3ca
(Mus musculus)Gene
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Synonyms: AW413465, RIKEN cDNA 2900074D19 gene, AI841391, CN, calcineurin, Calna1, expressed sequence AW413465, 2900074D19Rik, CnA, expressed sequence AI841391, calcineurin, alpha subunit, Calna, PP2BA alpha, Caln, PP2B alpha 1
Source: MGI:107164
Biotype: protein coding gene
Lrrk2
(Mus musculus)Gene
Name: leucine-rich repeat kinase 2
Synonyms: cDNA sequence, clone 3-75, Gm927, RIKEN cDNA 4921513O20 gene, AW561911, RIKEN cDNA D630001M17 gene, RIKEN cDNA 9330188B09 gene, 4921513O20Rik, D630001M17Rik, LOC381026, gene model 927, (NCBI), cI-46, 9330188B09Rik
Source: MGI:1913975
Biotype: protein coding gene
Fyn
(Mus musculus)Gene
Name: Fyn proto-oncogene
Synonyms: expressed sequence AW552119, AW552119, AI448320, Src Kinase p59, expressed sequence AI448320
Source: MGI:95602
Biotype: protein coding gene
Mtor
(Mus musculus)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: expressed sequence AI327068, 2610315D21Rik, flat, AI327068, RAFT1, flat-top, FKBP-rapamycin-associated protein FRAP, Frap1, mechanistic target of rapamycin (serine/threonine kinase), RAPT1, RIKEN cDNA 2610315D21 gene, FK506 binding protein 12-rapamycin associated protein 1
Source: MGI:1928394
Biotype: protein coding gene
GNAS
(Homo sapiens)Gene
Name: GNAS complex locus
Synonyms: ALEX, PHP1B, SgVI, PHP1A, PHP1C, G protein subunit alpha S, adenylate cyclase-stimulating G alpha protein, PITA3, guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas, neuroendocrine secretory protein, AHO, dJ806M20.3.3, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1, GSA, GPSA, guanine nucleotide regulatory protein, extra large alphas protein, MGC33735, alternative gene product encoded by XL-exon, C20orf45, GSP, secretogranin VI, POH, dJ309F20.1.1, NESP, GNAS1, AIMAH1, SCG6, NESP55
Source: HGNC:4392
Biotype: protein coding gene
Cabp1
(Mus musculus)Gene
Name: calcium binding protein 1
Synonyms: caldendrin
Source: MGI:1352750
Biotype: protein coding gene
Trpa1
(Mus musculus)Gene
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: Anktm1, ANKTM1
Source: MGI:3522699
Biotype: protein coding gene
MDM2
(Homo sapiens)Gene
Name: MDM2 proto-oncogene
Synonyms: oncoprotein Mdm2, HDMX, MDM2 proto-oncogene, E3 ubiquitin protein ligase, MGC71221, Mdm2, p53 E3 ubiquitin protein ligase homolog, ACTFS, Mdm2, transformed 3T3 cell double minute 2, p53 binding protein, HDM2 transcript variant MYO-18, MGC5370, hdm2, HDM2 transcript variant MYO-32, HDM2 transcript variant MYO-24, HDM2 transcript variant MYO-4, HDM2 transcript variant MYO-25, ubiquitin-protein ligase E3 Mdm2, MDM2 oncogene, E3 ubiquitin protein ligase, MDM2 variant FB28, double minute 2, human homolog of, p53-binding protein, HDM2 transcript variant MYO-1, HDM2 transcript variant MYO-26, Mdm2 p53 binding protein homolog, HDM2 transcript variant MYO-20, MDM2 variant FB30, E3 ubiquitin-protein ligase Mdm2, double minute 2, human homolog of, LSKB
Source: HGNC:6973
Biotype: protein coding gene
GNAO1
(Homo sapiens)Gene
Name: G protein subunit alpha o1
Synonyms: heterotrimeric guanine nucleotide-binding protein 1G, DKFZp686O0962, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, G-ALPHA-o, EIEE17, guanine nucleotide-binding protein G(o) subunit alpha, guanine nucleotide binding protein, alpha activating polypeptide O, GNAO, DEE17, HG1G, NEDIM, GO2-q chimeric G-protein, guanine nucleotide-binding regulatory protein 2, HLA-DQB1
Source: HGNC:4389
Biotype: protein coding gene
LRRK2
(Homo sapiens)Gene
Name: leucine rich repeat kinase 2
Synonyms: leucine-rich repeat serine/threonine-protein kinase 2, RIPK7, leucine-rich repeat kinase 2, ROCO2, augmented in rheumatoid arthritis 17, AURA17, PARK8, DARDARIN, Parkinson disease (autosomal dominant) 8
Source: HGNC:18618
Biotype: protein coding gene
CACNA1E
(Homo sapiens)Gene
Name: calcium voltage-gated channel subunit alpha1 E
Synonyms: BII, EIEE69, voltage-gated calcium channel alpha subunit Cav2.3, CACNL1A6, calcium channel, R type, alpha-1 polypeptide, isoform 6, voltage-dependent calcium channel alpha 1E subunit, gm139, voltage-dependent R-type calcium channel subunit alpha-1E, calcium channel, voltage-dependent, R type, alpha 1E subunit, brain calcium channel II, voltage-gated calcium channel alpha 1E subunit, calcium voltage-gated channel subunit alpha1 subunit E, calcium channel, voltage-dependent, l type, alpha 1e subunit, voltage-gated calcium channel subunit alpha Cav2.3, calcium channel, L type, alpha-1 polypeptide, DEE69, CACH6, Cav2.3, calcium channel, voltage-dependent, alpha 1E subunit, calcium channel, R type, alpha-1 polypeptide, calcium channel, L type, alpha-1 polypeptide, isoform 6
Source: HGNC:1392
Biotype: protein coding gene
egl-30
(Caenorhabditis elegans)Gene
Name: EGg Laying defective 30
Synonyms: M01D7.7, CELE_M01D7.7, gqa-1
Source: WB:WBGene00001196
Biotype: protein coding gene
Parp1
(Mus musculus)Gene
Name: poly (ADP-ribose) polymerase family, member 1
Synonyms: poly (ADP-ribose) polymerase, Adprt1, Parp-1, expressed sequence AI893648, Adprp, ARTD1, PARP, Adprt, sPARP-1, AI893648, RIKEN cDNA 5830444G22 gene, 5830444G22Rik, parp-1, C80510, expressed sequence C80510, ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1
Source: MGI:1340806
Biotype: protein coding gene