Version: 8.1.0Date: Fri Apr 18 2025
Gene Cellular Component: nucleus Molecular Function: metal ion binding
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, TRP53, FLJ92943, mutant p53 protein, tumor suppressor TP53, tumor protein 53, tumor suppressor p53, LFS1, BMFS5, p53 tumor suppressor, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
BRCA1
(Homo sapiens)Gene
Name: BRCA1 DNA repair associated
Synonyms: RNF53, early onset breast cancer 1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast cancer 1, BRCC1, BRCA1, DNA repair associated, RING finger protein 53, breast and ovarian cancer susceptibility protein 1, BRCA1/BRCA2-containing complex, subunit 1, breast cancer 1, early onset, Fanconi anemia, complementation group S, IRIS, breast cancer type 1 susceptibility protein, BRCAI, PNCA4, PSCP, protein phosphatase 1, regulatory subunit 53, BROVCA1, truncated BRCA1, breast cancer 1, FANCS, PPP1R53
Source: HGNC:1100
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
BRAF
(Homo sapiens)Gene
Name: B-Raf proto-oncogene, serine/threonine kinase
Synonyms: serine/threonine-protein kinase B-raf, RAFB1, B-RAF1, B-Raf serine/threonine-protein, v-raf murine sarcoma viral oncogene homolog B1, v-raf murine sarcoma viral oncogene homolog B, p94, B-Raf proto-oncogene serine/threonine-protein kinase (p94), proto-oncogene B-Raf, MGC138284, MGC126806, NS7, FLJ95109, B-raf, BRAF1, 94 kDa B-raf protein, BRAF-1, murine sarcoma viral (v-raf) oncogene homolog B1
Source: HGNC:1097
Biotype: protein coding gene
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide, beta-amyloid peptide(1-42), preA4, beta-amyloid peptide(1-40), cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, AD1, alpha-sAPP, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), alzheimer disease amyloid protein, protease nexin-II, amyloid beta A4 protein, CTFgamma, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, Alzheimer disease 2 (APOE*E4-associated, late onset), MGC1571, AD2
Source: HGNC:613
Biotype: protein coding gene
Hamp
(Rattus norvegicus)Gene
Name: hepcidin antimicrobial peptide
Synonyms: Hepc, hepcidin
Source: RGD:70971
Biotype: protein coding gene
Kit
(Mus musculus)Gene
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: Dominant white spotting, gsf spotted coat 1, c-KIT, Fdc, Gsfsco1, dominant spotting, Ssm, gsf spotted coat 5, SCO5, Bs, Tr-kit, SCO1, W, spotted sterile male, Gsfsow3, Steel Factor Receptor, CD117, Gsfsco5, phenotype like Sl or W 3, belly-spot, SOW3
Source: MGI:96677
Biotype: protein coding gene
GTS1
(Saccharomyces cerevisiae)Gene
Name: Glycine Threonine Serine repeat protein
Synonyms: YGL181W, LSR1, FHT1
Source: SGD:S000003149
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, Parkinson disease (autosomal dominant, Lewy body) 4, MGC110988, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, synuclein, alpha, alpha-synuclein, isoform NACP140, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
RAD27
(Saccharomyces cerevisiae)Gene
Name: RADiation sensitive
Synonyms: FEN1, ERC11, YKL113C, RTH1
Source: SGD:S000001596
Biotype: protein coding gene
Mpo
(Mus musculus)Gene
Name: myeloperoxidase
Synonyms: Not Available
Source: MGI:97137
Biotype: protein coding gene
ERCC5
(Homo sapiens)Gene
Name: ERCC excision repair 5, endonuclease
Synonyms: xeroderma pigmentosum, complementation group G, ERCC5-201, UVDR, ERCM2, xeroderma pigmentosum group G-complementing protein, XPG, COFS3, excision repair protein, excision repair cross-complementing rodent repair deficiency, complementation group 5, DNA repair protein complementing XP-G cells, excision repair cross-complementation group 5, XPG-complementing protein, DNA excision repair protein ERCC-5, xeroderma pigmentosum complementation group G protein, XPGC
Source: HGNC:3437
Biotype: protein coding gene
DMD
(Homo sapiens)Gene
Name: dystrophin
Synonyms: truncated dystrophin, DXS270, mutant dystrophin, dystrophin (muscular dystrophy, Duchenne and Becker types), DXS272, mental retardation, X-linked 85, DXS239, DXS206, MRX85, BMD, DXS230, DXS142, DXS164, DXS268, CMD3B, DXS269
Source: HGNC:2928
Biotype: protein coding gene
SIRT1
(Homo sapiens)Gene
Name: sirtuin 1
Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, regulatory protein SIR2 homolog 1, NAD-dependent protein deacetylase sirtuin-1, hSIRT1, hSIR2, sirtuin type 1, NAD-dependent deacetylase sirtuin-1
Source: HGNC:14929
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, cerebrovascular amyloid peptide, Alzheimer disease amyloid beta protein, protease nexin II, AL024401, RIKEN cDNA E030013M08 gene, expressed sequence AL024401, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
crb
(Drosophila melanogaster)Gene
Name: crumbs
Synonyms: l(3)07207, Crbs, CT19912, 0509/20, Crumbs, CG6383, 1384/04, Crb, CRB, crumb, crumbs, far, fat rhabdomere, l(3)S058104, DmCrb, lethal (3) 07207, l(3)S050920, l(3)j1B5, fat rhabdomeres
Source: FB:FBgn0259685
Biotype: protein coding gene
Adh1
(Mus musculus)Gene
Name: alcohol dehydrogenase 1 (class I)
Synonyms: Adh-1e, ADH-AA, Adh, alcohol dehydrogenase 1 temporal, liver, Adh-1, expressed sequence AI194826, alcohol dehydrogenase 1, electrophoretic, Adh1-t, alcohol dehydrogenase 1 complex, AI194826, class I alcohol dehydrogenase, Adh1a, Adh-1t, Adh1tl, Adh-1-t, Adh1-e, alcohol dehydrogenase 1 temporal
Source: MGI:87921
Biotype: protein coding gene
Dmd
(Mus musculus)Gene
Name: dystrophin, muscular dystrophy
Synonyms: mdx, X-linked muscular dystrophy, Duchenne muscular dystrophy, Dp71, DNADMD1, pke, pyruvate kinase expression, Dp427, dys
Source: MGI:94909
Biotype: protein coding gene
SOD1
(Homo sapiens)Gene
Name: superoxide dismutase 1
Synonyms: Cu/Zn superoxide dismutase, ALS, SOD, superoxide dismutase [Cu-Zn], indophenoloxidase A, HEL-S-44, superoxide dismutase 1, soluble, epididymis secretory protein Li 44, SOD, soluble, STAHP, hSod1, superoxide dismutase, cystolic, superoxide dismutase, ALS1, IPOA, homodimer
Source: HGNC:11179
Biotype: protein coding gene
Braf
(Mus musculus)Gene
Name: Braf transforming gene
Synonyms: expressed sequence C87398, expressed sequence AA120551, expressed sequence AA387315, Braf-2, Braf2, AA387315, DNA segment, Chr 6, ERATO Doi 631, expressed, RIKEN cDNA 9930012E13 gene, C87398, Braf transforming gene 2, AA120551, expressed sequence AA473386, D6Ertd631e, AA473386, 9930012E13Rik
Source: MGI:88190
Biotype: protein coding gene
Apex2
(Mus musculus)Gene
Name: apurinic/apyrimidinic endonuclease 2
Synonyms: C430040P13Rik, RIKEN cDNA C430040P13 gene, Ape2
Source: MGI:1924872
Biotype: protein coding gene
RECQL
(Homo sapiens)Gene
Name: RecQ like helicase
Synonyms: RecQ protein-like (DNA helicase Q1-like), RecQ1, recQ protein-like 1, DNA helicase, RecQ-like type 1, ATP-dependent DNA helicase Q1, DNA helicase Q1-like, RECON, DNA 3'-5' helicase Q1, DNA-dependent ATPase Q1, RecQ helicase-like, RECQL1
Source: HGNC:9948
Biotype: protein coding gene
Acly
(Rattus norvegicus)Gene
Name: ATP citrate lyase
Synonyms: ATP-citrate synthase, MGC124629, citrate cleavage enzyme, Clatp, ACL, ATP-citrate (pro-S-)-lyase
Source: RGD:2018
Biotype: protein coding gene
SGS1
(Saccharomyces cerevisiae)Gene
Name: Slow Growth Suppressor
Synonyms: YMR190C
Source: SGD:S000004802
Biotype: protein coding gene
CHEK2
(Homo sapiens)Gene
Name: checkpoint kinase 2
Synonyms: CDS1, HuCds1, PP1425, serine/threonine-protein kinase Chk2, TPDS4, checkpoint-like protein CHK2, CHK2 checkpoint homolog, RAD53, cds1 homolog, truncated checkpoint kinase 2, CHK2, LFS2, hCds1
Source: HGNC:16627
Biotype: protein coding gene
Cdkn1a
(Mus musculus)Gene
Name: cyclin dependent kinase inhibitor 1A
Synonyms: CDKI, Cip1, p21Cip1, P21, Cdkn1, p21, cyclin dependent kinase inhibitor, CIP1, UV96, p21WAF, Waf1, CAP20, SDI1, mda6
Source: MGI:104556
Biotype: protein coding gene
Ptgs2
(Mus musculus)Gene
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX-2, Cox-2, PHS II, Cox2, Pghs2, cyclooxygenase-2, prostaglandin G/H synthase, COX2, PHS-2, PGHS-2, cyclooxygenase 2, Tis10
Source: MGI:97798
Biotype: protein coding gene
TSSK2
(Homo sapiens)Gene
Name: testis specific serine kinase 2
Synonyms: TSK2, SPOGA2, serine/threonine kinase 22B (spermiogenesis associated), testis-specific serine/threonine-protein kinase 2, testicular secretory protein Li 61, testis-specific kinase 2, serine/threonine-protein kinase 22B, spermiogenesis associated 2, testis-specific serine kinase 2, testis specific serine threonine kinase 2, TSSK-2, FLJ38613, DGS-G, diGeorge syndrome protein G, TSK-2, STK22B
Source: HGNC:11401
Biotype: protein coding gene
Mmp2
(Mus musculus)Gene
Name: matrix metallopeptidase 2
Synonyms: GelA, MMP-2, collagenase IVA, basement membrane, 72 kDa, gelatinase A, Clg4a, 72kDa type IV collagenase, 72kDa gelatinase
Source: MGI:97009
Biotype: protein coding gene
GAL4
(Saccharomyces cerevisiae)Gene
Name: GALactose metabolism
Synonyms: YPL248C, GAL81
Source: SGD:S000006169
Biotype: protein coding gene
ACE2
(Saccharomyces cerevisiae)Gene
Name: Activator of CUP1 Expression
Synonyms: YLR131C
Source: SGD:S000004121
Biotype: protein coding gene
SOD1
(Saccharomyces cerevisiae)Gene
Name: SuperOxide Dismutase
Synonyms: YJR104C, CRS4
Source: SGD:S000003865
Biotype: protein coding gene
Prkn
(Mus musculus)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkinson disease (autosomal recessive, juvenile) 2, parkin, Park2, Parkin, Park
Source: MGI:1355296
Biotype: protein coding gene
Brca1
(Mus musculus)Gene
Name: breast cancer 1, early onset
Synonyms: BRCA-1
Source: MGI:104537
Biotype: protein coding gene
N
(Drosophila melanogaster)Gene
Name: Notch
Synonyms: 16-178, 16-55, RICN, Abruptex, Chp, Co, EG:163A10.2, Confluens, split, anon-EST:Liang-1.12, dNotch, Ax, Nicd, Chopped, Notch, strawberry, NOTCH, clone 1.12, co, shd, spl, 1.1, l(1)3Cb, nd, CG3936, NICD, notchoid, n[fah], notch, fa, CT13012, EG:140G11.1, NECD, facet, l(1)Ax, l(1)N, swb
Source: FB:FBgn0004647
Biotype: protein coding gene
Rag2
(Mus musculus)Gene
Name: recombination activating gene 2
Synonyms: Rag-2
Source: MGI:97849
Biotype: protein coding gene
Foxp2
(Mus musculus)Gene
Name: forkhead box P2
Synonyms: 2810043D05Rik, RGD1559697, RIKEN cDNA 2810043D05 gene, AI449000, expressed sequence AI449000, D0Kist7, DNA segment, KIST 7
Source: MGI:2148705
Biotype: protein coding gene
CCR4
(Saccharomyces cerevisiae)Gene
Name: Carbon Catabolite Repression
Synonyms: YAL021C, FUN27, NUT21
Source: SGD:S000000019
Biotype: protein coding gene
notch1b
(Danio rerio)Gene
Name: notch receptor 1b
Synonyms: wu:fc55e11, etID309871.5
Source: ZFIN:ZDB-GENE-990415-183
Biotype: protein coding gene
MRE11
(Homo sapiens)Gene
Name: MRE11 homolog, double strand break repair nuclease
Synonyms: HNGS1, double-strand break repair protein MRE11A, MRE11A, MRE11 homolog A, DNA recombination and repair protein, MRE11B, endo/exonuclease Mre11, meiotic recombination 11 homolog A, double-strand break repair protein MRE11, MRE11 homolog A, double strand break repair nuclease, MRE11 meiotic recombination 11-like protein A, MRE11 meiotic recombination 11 homolog A, ATLD, AT-like disease, MRE11 homolog 1, MRE11 double strand break repair nuclease A, MRE11 homolog, double strand break repair nuclease A, meiotic recombination 11 homolog 1
Source: HGNC:7230
Biotype: protein coding gene
Foxp3
(Mus musculus)Gene
Name: forkhead box P3
Synonyms: RGD1562112, sf, scurfy, scurfin, JM2
Source: MGI:1891436
Biotype: protein coding gene
Calb1
(Mus musculus)Gene
Name: calbindin 1
Synonyms: calbindin, calbindin-D (28k), Calb-1, Brain-2, CaBP28K, Calb, calbindin-D28K, CalbindinD28K, CB
Source: MGI:88248
Biotype: protein coding gene
NT5E
(Homo sapiens)Gene
Name: 5'-nucleotidase ecto
Synonyms: IMP-specific 5'-nucleotidase, thymidylate 5'-phosphatase, 5'-nucleotidase, ecto (CD73), CD73, NT, Purine 5-Prime-Nucleotidase, eN, eNT, CALJA, 5'-nucleotidase, NT5, 5'-deoxynucleotidase, ecto-5'-nucleotidase, 5 nucleotidase, E5NT, 5' nucleotidase (CD73), 5'-NT, NTE
Source: HGNC:8021
Biotype: protein coding gene
Pparg
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: PPARgamma2, Nr1c3, Ppar-gamma2, PPARgamma, PPAR-gamma
Source: MGI:97747
Biotype: protein coding gene
SP2
(Homo sapiens)Gene
Name: Sp2 transcription factor
Synonyms: transcription factor Sp2
Source: HGNC:11207
Biotype: protein coding gene
Nrxn1
(Mus musculus)Gene
Name: neurexin I
Synonyms: RIKEN cDNA 9330127H16 gene, neurexin I beta, Nrxn1b, RIKEN cDNA A230068P09 gene, RIKEN cDNA 1700062G21 gene, 1700062G21Rik, neurexin I alpha, mKIAA0578, alpha-latrotoxin receptor (calcium-dependent), A230068P09Rik, 9330127H16Rik
Source: MGI:1096391
Biotype: protein coding gene
KLF10
(Homo sapiens)Gene
Name: KLF transcription factor 10
Synonyms: transforming growth factor-beta-inducible early growth response protein 1, TGFB inducible early growth response, Kruppel like factor 10, TIEG-1, Kruppel-like factor 10, zinc finger transcription factor TIEG, TGFB-inducible early growth response protein 1, TIEG, EGRA, early growth response-alpha, EGR-alpha, Krueppel-like factor 10, TIEG1
Source: HGNC:11810
Biotype: protein coding gene