Version: 8.0.0
Date: Tue Jan 28 2025
1,493 results for aifm1

Aifm1

(Mus musculus)
Gene
Name: apoptosis-inducing factor, mitochondrion-associated 1
Synonyms: Pdcd8, Hq, programmed cell death 8, apoptosis-inducing factor, AIFsh2, harlequin, AIF, Aif
Source: MGI:1349419
Biotype: protein coding gene
Symbol: Aifm1 (Mmu)
Symbol: Aifm1
Automated Gene Synopsis: Orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1).
Strict Orthology Symbols: aifm1
Alleles: Aifm1 (Mmu)...Aifm1 (Mmu)...Aifm1 (Mmu)...Aifm1 (Mmu)...Aifm1 (Mmu)

Aifm1

(Rattus norvegicus)
Gene
Name: apoptosis inducing factor, mitochondria associated 1
Synonyms: programmed cell death 8 (apoptosis-inducing factor), Pdcd8, apoptosis-inducing factor, mitochondrion-associated 1, apoptosis-inducing factor 1, mitochondrial-like, programmed cell death protein 8, programmed cell death 8, apoptosis-inducing factor 1, mitochondrial, LOC103694586, Aif
Source: RGD:620817
Biotype: protein coding gene
Symbol: Aifm1 (Rno)
Symbol: Aifm1
Gene Synopsis: Orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1); PARTICIPATES IN ceramide
Automated Gene Synopsis: Orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1).
Strict Orthology Symbols: aifm1

aifm1

(Danio rerio)
Gene
Name: apoptosis inducing factor mitochondrion associated 1
Synonyms: pdcd8, zgc:91994, AIF
Source: ZFIN:ZDB-GENE-030826-11
Biotype: protein coding gene
Symbol: aifm1 (Dre)
Symbol: aifm1
Automated Gene Synopsis: Orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1).
Strict Orthology Symbols: aifm1

AIFM1

(Homo sapiens)
Gene
Name: apoptosis inducing factor mitochondria associated 1
Synonyms: COXPD6, NAMSD, neuropathy, axonal, motor-sensory with deafness and mental retardation (Cowchock syndrome), PDCD8, apoptosis inducing factor, mitochondria associated 1, COWCK, striatal apoptosis-inducing factor, CMT2D, Neuropathy, axonal motor-sensory, with deafness and mental retardation, AUNX1, apoptosis-inducing factor 1, mitochondrial, testicular secretory protein Li 4, apoptosis-inducing factor, mitochondrion-associated, 1, CMTX4, auditory neuropathy, X-linked recessive 1, programmed cell death 8 (apoptosis-inducing factor), DFNX5, MGC111425, AIF, NADMR, SEMDHL
Source: HGNC:8768
Biotype: protein coding gene
Symbol: AIFM1 (Hsa)
Symbol: AIFM1
Strict Orthology Symbols: aifm1

aifm1

(Xenopus tropicalis)
Gene
Name: apoptosis inducing factor, mitochondria associated 1
Synonyms: apoptosis inducing factor, mitochondria associated 1, pdcd8, aifm1, programmed cell death 8
Source: Xenbase:XB-GENE-1016872
Biotype: gene
Symbol: aifm1 (Xtr)
Symbol: aifm1
Synonyms: aifm1...aifm1...aifm1
Strict Orthology Symbols: aifm1

aifm1.L

(Xenopus laevis)
Gene
Name: apoptosis inducing factor, mitochondria associated 1
Synonyms: apoptosis inducing factor, mitochondria associated 1, aifm1.L, programmed cell death 8, pdcd8
Source: Xenbase:XB-GENE-6486001
Biotype: gene
Symbol: aifm1.L (Xla)
Automated Gene Synopsis: Orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1).
Strict Orthology Symbols: aifm1
Symbol: aifm1.L

Aifm1tm1.2Geno

(Mus musculus)
Allele/Variant
Source: MGI:6728504
Genes: Aifm1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Aifm1 (Mmu)
Genes: Aifm1 (Mmu)
Symbol: Aifm1tm1.2Geno

Aifm1em1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7376192
Genes: Aifm1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Aifm1 (Mmu)
Genes: Aifm1 (Mmu)
Symbol: Aifm1em1Gpt

Aifm1tm2Pngr

(Mus musculus)
Allele/Variant
Source: MGI:3686777
Genes: Aifm1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Aifm1 (Mmu)
Genes: Aifm1 (Mmu)
Symbol: Aifm1tm2Pngr

Aifm1em1Smoc

(Mus musculus)
Allele/Variant
Source: MGI:7626368
Genes: Aifm1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Aifm1 (Mmu)
Genes: Aifm1 (Mmu)
Symbol: Aifm1em1Smoc

Aifm1tm2.1Pngr

(Mus musculus)
Allele/Variant
Source: MGI:3851178
Genes: Aifm1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Aifm1 (Mmu)
Genes: Aifm1 (Mmu)
Symbol: Aifm1tm2.1Pngr

Aifm1Hq

(Mus musculus)
Allele/Variant
Source: MGI:1861097
Genes: Aifm1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: mitochondrial complex I deficiency
Variant Name: Not Available
Symbol: Aifm1 (Mmu)
Genes: Aifm1 (Mmu)
Symbol: Aifm1Hq

Aifm1tm1.1Geno

(Mus musculus)
Allele/Variant
Source: MGI:6728503
Genes: Aifm1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Aifm1 (Mmu)
Genes: Aifm1 (Mmu)
Symbol: Aifm1tm1.1Geno

Aifm1em1Kazk

(Mus musculus)
Allele/Variant
Source: MGI:7716593
Genes: Aifm1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Aifm1 (Mmu)
Genes: Aifm1 (Mmu)
Symbol: Aifm1em1Kazk

AIFM1P1

(Homo sapiens)
Gene
Name: AIFM1 pseudogene 1
Synonyms: apoptosis inducing factor, mitochondria associated 1 pseudogene 1
Source: HGNC:44884
Biotype: pseudogene
Symbol: AIFM1P1 (Hsa)
Symbol: AIFM1P1

Aifm1Hq/Aifm1Hq [background:] B6CBACa Aw-J/A-Aifm1Hq/J

(Mus musculus)
Model
Id: MGI:2387325
Synonyms: Not Available
Symbol: Aifm1/Aifm1 [background:] B6CBACa A/A-Aifm1/J (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Aifm1 [background:] B6CBACa A/A-Aifm1/J

Aifm1Hq/Aifm1Hq Apaf1Gt(IRESBetageo)XIX18Pgr/Apaf1Gt(IRESBetageo)XIX18Pgr [background:] involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

(Mus musculus)
Model
Id: MGI:3699821
Synonyms: Not Available
Symbol: Aifm1/Aifm1 Apaf1/Apaf1 [background:] involves
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Aifm1 Apaf1/Apaf1 [background:] involves

Aifm1Hq/Aifm1+ [background:] B6CBACa Aw-J/A-Aifm1Hq/J

(Mus musculus)
Model
Id: MGI:3707536
Synonyms: Not Available
Symbol: Aifm1/Aifm1<+> [background:] B6CBACa A/A-Aifm1/J (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Aifm1<+> [background:] B6CBACa A/A-Aifm1/J

Aifm1tm2Pngr/Aifm1+ Tmem163Tg(ACTB-cre)2Mrt/0 [background:] involves: 129P2/OlaHsd * FVB/N

(Mus musculus)
Model
Id: MGI:3687266
Synonyms: Not Available
Symbol: Aifm1/Aifm1<+> Tmem163/0 [background:] involves: 129P2/OlaHsd * FVB/N (Mmu
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Aifm1<+> Tmem163/0 [background:] involves: 129P2/OlaHsd * FVB/N

Aifm1tm2.1Pngr/Aifm1tm2.1Pngr [background:] involves: 129P2/OlaHsd * FVB/N

(Mus musculus)
Model
Id: MGI:3851181
Synonyms: Not Available
Symbol: Aifm1/Aifm1 [background:] involves: 129P2/OlaHsd * FVB/N (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Aifm1 [background:] involves: 129P2/OlaHsd * FVB/N

Aifm1tm2Pngr/Y Foxg1tm1(cre)Skm/Foxg1+ [background:] involves: 129P2/OlaHsd

(Mus musculus)
Model
Id: MGI:3687280
Synonyms: Not Available
Symbol: Aifm1/Y Foxg1/Foxg1<+> [background:] involves: 129P2/OlaHsd (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Y Foxg1/Foxg1<+> [background:] involves: 129P2/OlaHsd

Aifm1tm2Pngr/Y Tmem163Tg(ACTB-cre)2Mrt/0 [background:] involves: 129P2/OlaHsd * FVB/N

(Mus musculus)
Model
Id: MGI:3687265
Synonyms: Not Available
Symbol: Aifm1/Y Tmem163/0 [background:] involves: 129P2/OlaHsd * FVB/N (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Y Tmem163/0 [background:] involves: 129P2/OlaHsd * FVB/N

Aifm1tm1Pngr/Y [background:] 129P2/OlaHsd-Aifm1tm1Pngr

(Mus musculus)
Model
Id: MGI:3851184
Synonyms: Not Available
Symbol: Aifm1/Y [background:] 129P2/OlaHsd-Aifm1 (Mmu)
Name: Aifm1/Y [background:] 129P2/OlaHsd-Aifm1

Aifm1Hq/Y [background:] involves: CF-1

(Mus musculus)
Model
Id: MGI:3699816
Synonyms: Not Available
Symbol: Aifm1/Y [background:] involves: CF-1 (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Y [background:] involves: CF-1

Aifm1Hq/Aifm1Hq [background:] involves: CF-1

(Mus musculus)
Model
Id: MGI:3699815
Synonyms: Not Available
Symbol: Aifm1/Aifm1 [background:] involves: CF-1 (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Aifm1 [background:] involves: CF-1

Aifm1tm2.1Pngr/Y [background:] involves: 129P2/OlaHsd * FVB/N

(Mus musculus)
Model
Id: MGI:3851180
Synonyms: Not Available
Symbol: Aifm1/Y [background:] involves: 129P2/OlaHsd * FVB/N (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Y [background:] involves: 129P2/OlaHsd * FVB/N

Aifm1tm2.1Pngr/Aifm1+ [background:] involves: 129P2/OlaHsd * FVB/N

(Mus musculus)
Model
Id: MGI:3851179
Synonyms: Not Available
Symbol: Aifm1/Aifm1<+> [background:] involves: 129P2/OlaHsd * FVB/N (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Aifm1<+> [background:] involves: 129P2/OlaHsd * FVB/N

Aifm1Hq/Y [background:] B6CBACa Aw-J/A-Aifm1Hq/J

(Mus musculus)
Model
Id: MGI:2387326
Synonyms: Not Available
Symbol: Aifm1/Y [background:] B6CBACa A/A-Aifm1/J (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Y [background:] B6CBACa A/A-Aifm1/J

Aifm1tm2Pngr/Y Tg(Ckmm-cre)5Khn/0 [background:] involves: 129P2/OlaHsd * FVB

(Mus musculus)
Model
Id: MGI:3687267
Synonyms: Not Available
Symbol: Aifm1/Y Tg(Ckmm-cre)5Khn/0 [background:] involves: 129P2/OlaHsd * FVB (Mmu)
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Aifm1/Y Tg(Ckmm-cre)5Khn/0 [background:] involves: 129P2/OlaHsd * FVB

AIF

(Drosophila melanogaster)
Gene
Name: Apoptosis inducing factor
Synonyms: SD03428p, dAIF, DmAIF, Apoptosis Inducing Factor, CG7263, AIF, aif
Source: FB:FBgn0031392
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1).
Strict Orthology Symbols: aifm1

wah-1

(Caenorhabditis elegans)
Gene
Name: Worm AIF (apoptosis inducing factor) Homolog 1
Synonyms: CELE_Y56A3A.32, Y56A3A.32
Source: WB:WBGene00006937
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human AIFM1 (apoptosis inducing factor mitochondria associated 1).
Strict Orthology Symbols: aifm1

TXNDC12

(Homo sapiens)
Gene
Name: thioredoxin domain containing 12
Synonyms: hTLP19, TLP19, endoplasmic reticulum resident protein 18, endoplasmic reticulum resident protein 19, ER protein 18, endoplasmic reticulum thioredoxin superfamily member, 18 kDa, ER protein 19, thioredoxin-like protein p19, hAG-1, AG1, thioredoxin domain-containing protein 12, PDIA16, ERP18, ERP19, ERP16, anterior gradient homolog 1, protein disulfide isomerase family A, member 16, thioredoxin domain containing 12 (endoplasmic reticulum), endoplasmic reticulum protein ERp19, AGR1
Source: HGNC:24626
Biotype: protein coding gene
Strict Orthology Symbols: aifm1

TRR2

(Saccharomyces cerevisiae)
Gene
Name: ThioRedoxin Reductase
Synonyms: YHR106W
Source: SGD:S000001148
Biotype: protein coding gene
Strict Orthology Symbols: aifm1

TRR1

(Saccharomyces cerevisiae)
Gene
Name: ThioRedoxin Reductase
Synonyms: YDR353W
Source: SGD:S000002761
Biotype: protein coding gene
Strict Orthology Symbols: aifm1

X-linked deafness 5

Disease
Source: DOID:0111741
Definition: A neuropathy characterized by childhood onset of auditory neuropathy and later onset of distal sensory impairment due to diffuse peripheral neuropathy that has_material_basis_in hemizygous or homozygous mutation in the AIFM1 gene on chromosome Xq26.1.
Genes: aifm1 (Dre)...aifm1.L (Xla)...Aifm1 (Mmu)...aifm1 (Xtr)...AIFM1 (Hsa)

combined oxidative phosphorylation deficiency 6

Disease
Source: DOID:0111502
Definition: A combined oxidative phosphorylation deficiency that has_material_basis_in hemizygous mutation in the AIFM1 gene on chromosome Xq26.1.
Genes: aifm1 (Dre)...aifm1.L (Xla)...Aifm1 (Mmu)...aifm1 (Xtr)...AIFM1 (Hsa)

Charcot-Marie-Tooth disease X-linked recessive 4

Disease
Source: DOID:0110212
Definition: A Charcot-Marie-Tooth disease X-linked that has_material_basis_in mutation in the AIFM1 gene on chromosome Xq26.
Genes: aifm1 (Dre)...aifm1.L (Xla)...Aifm1 (Mmu)...aifm1 (Xtr)...AIFM1 (Hsa)

regulation of apoptotic DNA fragmentation

Gene Ontology
Source: GO:1902510
Synonyms:
  • regulation of DNA catabolic process during apoptosis
  • regulation of DNA catabolism during apoptosis
Branch: biological process
Genes: Aifm1 (Mmu)...AIFM1 (Hsa)...Aifm1 (Rno)

mitochondrial respiratory chain complex assembly

Gene Ontology
Source: GO:0033108
Synonyms: Not Available
Branch: biological process
Genes: Aifm1 (Mmu)...AIFM1 (Hsa)...aifm1 (Dre)...Aifm1 (Rno)

cellular response to aldosterone

Gene Ontology
Source: GO:1904045
Synonyms: Not Available
Branch: biological process
Genes: Aifm1 (Mmu)...AIFM1 (Hsa)...Aifm1 (Rno)

positive regulation of necroptotic process

Gene Ontology
Source: GO:0060545
Synonyms:
  • positive regulation of necroptosis
Branch: biological process
Genes: Aifm1 (Mmu)...AIFM1 (Hsa)...Aifm1 (Rno)

mitochondrial complex I deficiency

Disease
Source: DOID:0060536
Definition: A mitochondrial metabolism disease characterized by a wide range of manifestations including marked and often fatal lactic acidosis, cardiomyopathy, leukoencephalopathy, pure myopathy and hepatopathy with tubulopathy. Among the numerous clinical phenotypes observed are Leigh syndrome, Leber hereditary optic neuropathy and MELAS syndrome. It can have material basis in mutations in multiple different genes, both nuclear-encoded and mitochondrial-encoded.
Genes: aifm1 (Xtr)...AIFM1 (Hsa)...Aifm1 (Mmu)...aifm1 (Dre)...Aifm1 (Rno)
Alleles: Aifm1 (Mmu)

poly-ADP-D-ribose binding

Gene Ontology
Source: GO:0072572
Synonyms:
  • pADPr binding
  • poly-ADP-ribose binding
Branch: molecular function
Genes: Aifm1 (Mmu)...AIFM1 (Hsa)...Aifm1 (Rno)

NAD(P)H oxidase H2O2-forming activity

Gene Ontology
Source: GO:0016174
Synonyms:
  • NAD(P)H oxidase activity
  • NAD(P)H:oxygen oxidoreductase activity
Branch: molecular function
Genes: Aifm1 (Mmu)...AIFM1 (Hsa)...aifm1 (Dre)...Aifm1 (Rno)

dilated cardiomyopathy 1H

Disease
Source: DOID:0110429
Definition: A dilated cardiomyopathy that has_material_basis_in variation in the chromosome region 2q14-q22.
Genes: AIFM1 (Hsa)...Aifm1 (Mmu)...aifm1 (Xtr)...aifm1 (Dre)...Aifm1 (Rno)

protein import into mitochondrial intermembrane space

Gene Ontology
Source: GO:0045041
Synonyms:
  • mitochondrial intermembrane space protein import
  • protein import into mitochondrial IMS
Branch: biological process
Genes: Aifm1 (Mmu)...AIFM1 (Hsa)...Aifm1 (Rno)

spint1ahi2217Tg/hi2217Tg; nz50Tg/nz50Tg + CRISPR1-aifm1

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-230926-15
Synonyms: Not Available
Genes: aifm1 (Dre)
Name: spint1a; nz50Tg/nz50Tg + CRISPR1-aifm1

response to L-glutamate

Gene Ontology
Source: GO:1902065
Synonyms: Not Available
Branch: biological process
Genes: Aifm1 (Mmu)...AIFM1 (Hsa)...Aifm1 (Rno)

oxidoreductase activity, acting on NAD(P)H

Gene Ontology
Source: GO:0016651
Synonyms:
  • NAD(P)H dehydrogenase
  • oxidoreductase activity, acting on NADH or NADPH
Branch: molecular function
Genes: AIFM1 (Hsa)...Aifm1 (Mmu)...Aifm1 (Rno)

Apaf1Gt(IRESBetageo)XIX18Pgr/Apaf1Gt(IRESBetageo)XIX18Pgr Aifm1tm2Pngr/Y Foxg1tm1(cre)Skm/Foxg1+ [background:] involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

(Mus musculus)
Model
Id: MGI:3687281
Synonyms: Not Available
Genes: Aifm1 (Mmu)
Alleles: Aifm1 (Mmu)
Name: Apaf1/Apaf1 Aifm1/Y Foxg1/Foxg1
Symbol: Apaf1/Apaf1 Aifm1/Y Foxg1/Foxg1