[object Object]

Category

1,294 results for hadhb

Page 1 of 26

hadhb

(Danio rerio)

Gene

Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Synonyms: fb14g10, zgc:56274, wu:fb14g10

Source: ZFIN:ZDB-GENE-030131-8550

Biotype: protein coding gene

Symbol: hadhb (Dre)

Symbol: hadhb

Automated Gene Synopsis: Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Strict Orthology Symbols: hadhb

Disease (6)

Hadhb

(Mus musculus)

Gene

Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Synonyms: TP-beta, 4930479F15Rik, Mtpb, RIKEN cDNA 4930479F15 gene

Source: MGI:2136381

Biotype: protein coding gene

Symbol: Hadhb (Mmu)

Symbol: Hadhb

Automated Gene Synopsis: Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Strict Orthology Symbols: hadhb

Alleles: Hadhb (Mmu)...Hadhb (Mmu)...Hadhb (Mmu)...Hadhb (Mmu)...Hadhb (Mmu)

Hadhb

(Rattus norvegicus)

Gene

Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Synonyms: hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit, trifunctional enzyme subunit beta, mitochondrial, TP-beta, hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit, mitochondrial trifunctional protein, beta subunit

Source: RGD:620513

Biotype: protein coding gene

Symbol: Hadhb (Rno)

Symbol: Hadhb

Gene Synopsis: Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Automated Gene Synopsis: Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Strict Orthology Symbols: hadhb

HADHB

(Homo sapiens)

Gene

Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Synonyms: mitochondrial trifunctional enzyme, beta subunit, hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit, TP-BETA, hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit, acetyl-CoA acyltransferase, trifunctional enzyme subunit beta, mitochondrial, MSTP029, MTPD2, hydroxyacyl-Coenzyme A (CoA) dehydrogenase, beta subunit, beta-ketothiolase, ECHB, 3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein, beta subunit, MGC87480, 2-enoyl-Coenzyme A (CoA) hydratase, beta subunit, MTPB, mitochondrial trifunctional protein, beta subunit, MTPD

Source: HGNC:4803

Biotype: protein coding gene

Symbol: HADHB (Hsa)

Symbol: HADHB

Strict Orthology Symbols: hadhb

hadhb

(Xenopus tropicalis)

Gene

Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Synonyms: hadhb, hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta, echb, tp-beta, mtpb, mstp029

Source: Xenbase:XB-GENE-1009673

Biotype: gene

Symbol: hadhb

Symbol: hadhb (Xtr)

Automated Gene Synopsis: Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Synonyms: hadhb...hadhb...hadhb

Strict Orthology Symbols: hadhb

Disease (6)

hadhb.S

(Xenopus laevis)

Gene

Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Synonyms: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta, echb, tp-beta, hadhb.S, mtpb, mstp029

Source: Xenbase:XB-GENE-1009676

Biotype: gene

Symbol: hadhb.S (Xla)

Automated Gene Synopsis: Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Strict Orthology Symbols: hadhb

Symbol: hadhb.S

Disease (3)

hadhb.L

(Xenopus laevis)

Gene

Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Synonyms: hadhb.L, hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta, echb, tp-beta, mtpb, mstp029

Source: Xenbase:XB-GENE-17344980

Biotype: gene

Symbol: hadhb.L (Xla)

Automated Gene Synopsis: Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Strict Orthology Symbols: hadhb

Symbol: hadhb.L

Disease (3)

Hadhb^em1(IMPC)Bay

(Mus musculus)

Allele/Variant

Source: MGI:6285597

Genes: Hadhb (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hadhb (Mmu)

Genes: Hadhb (Mmu)

Symbol: Hadhb^em1(IMPC)Bay

Hadhb^em1Smoc

(Mus musculus)

Allele/Variant

Source: MGI:7766168

Genes: Hadhb (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hadhb (Mmu)

Genes: Hadhb (Mmu)

Symbol: Hadhb^em1Smoc

Gene (1)

Hadhb^em1Gpt

(Mus musculus)

Allele/Variant

Source: MGI:7300115

Genes: Hadhb (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hadhb (Mmu)

Genes: Hadhb (Mmu)

Symbol: Hadhb^em1Gpt

Gene (1)

Hadhb^m1Ytc

(Mus musculus)

Allele/Variant

Source: MGI:3698125

Genes: Hadhb (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hadhb (Mmu)

Genes: Hadhb (Mmu)

Symbol: Hadhb^m1Ytc

Hadhb^{tm1a(KOMP)Wtsi}

(Mus musculus)

Allele/Variant

Source: MGI:4880972

Genes: Hadhb (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hadhb (Mmu)

Genes: Hadhb (Mmu)

Symbol: Hadhb^{tm1a(KOMP)Wtsi}

Gene (1)

Hadhb^em2Cya

(Mus musculus)

Allele/Variant

Source: MGI:7584228

Genes: Hadhb (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hadhb (Mmu)

Genes: Hadhb (Mmu)

Symbol: Hadhb^em2Cya

Gene (1)

HADHBP1

(Homo sapiens)

Gene

Name: HADHB pseudogene 1

Synonyms: hydroxyacyl-Coenzyme A dehydrogenase\/3-ketoacyl-Coenzyme A thiolase\/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (HADHB)(HADH) pseudogene, AC112656.1

Source: HGNC:54887

Biotype: pseudogene

Symbol: HADHBP1 (Hsa)

Symbol: HADHBP1

Hadhb-ps

(Mus musculus)

Gene

Name: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta, pseudogene

Synonyms: OTTMUSG00000015054, Gm13910, predicted gene 13910, predicted gene, OTTMUSG00000015054

Source: MGI:3651143

Biotype: pseudogene

Symbol: Hadhb-ps (Mmu)

Symbol: Hadhb-ps

Hadhb^em1(IMPC)Bay/Hadhb⁺ [background:] C57BL/6N-Hadhb^em1(IMPC)Bay/BayMmucd

(Mus musculus)

Model

Id: MGI:6696769

Synonyms: Not Available

Symbol: Hadhb/Hadhb<+> [background:] C57BL/6N-Hadhb/BayMmucd (Mmu)

Genes: Hadhb (Mmu)

Alleles: Hadhb (Mmu)

Name: Hadhb/Hadhb<+> [background:] C57BL/6N-Hadhb/BayMmucd

Gene (1)

Hadhb^m1Ytc/Hadhb^m1Ytc [background:] C57BL/6J-Hadhb^m1Yuan

(Mus musculus)

Model

Id: MGI:3698531

Synonyms: Not Available

Symbol: Hadhb/Hadhb [background:] C57BL/6J-Hadhb (Mmu)

Genes: Hadhb (Mmu)

Alleles: Hadhb (Mmu)

Name: Hadhb/Hadhb [background:] C57BL/6J-Hadhb

Gene (1)

Hadhb^em1(IMPC)Bay/Hadhb^em1(IMPC)Bay [background:] C57BL/6N-Hadhb^em1(IMPC)Bay/BayMmucd

(Mus musculus)

Model

Id: MGI:6731345

Synonyms: Not Available

Symbol: Hadhb/Hadhb [background:] C57BL/6N-Hadhb/BayMmucd (Mmu)

Genes: Hadhb (Mmu)

Alleles: Hadhb (Mmu)

Name: Hadhb/Hadhb [background:] C57BL/6N-Hadhb/BayMmucd

Gene (1)

Mtpβ

(Drosophila melanogaster)

Gene

Name: Mitochondrial trifunctional protein beta subunit

Synonyms: l(2)k09828, Mtpbeta, Thiolase, MTP, dHADHB, ACoT, CG4581, thiolase

Source: FB:FBgn0025352

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Strict Orthology Symbols: hadhb

hadb-1

(Caenorhabditis elegans)

Gene

Name: Hydroxyacyl-CoA Dehydrogenase trifunctional multienzyme complex subunit Beta 1

Synonyms: CELE_B0303.3, B0303.3

Source: WB:WBGene00015125

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

Strict Orthology Symbols: hadhb

mitochondrial trifunctional protein deficiency

Disease

Source: DOID:0111277

Definition: A lipid metabolism disorder characterized by abnormal fatty acid oxidation resulting a wide range of clinical manifestations from servere neonatal symptoms including cardiomyopathy, hypoglycemia, metabolic acidosis, skeletal myopathy and neuropathy, liver disease and death to a more mild phenotype including peripheral polyneuropathy, episodic rhabdomyolysis and pigmentary retinopathy.

Genes: Hadhb (Mmu)...HADHB (Hsa)...Hadhb (Rno)...hadhb (Dre)...hadhb (Xtr)

acetyl-CoA C-myristoyltransferase activity

Gene Ontology

Source: GO:0050633

Synonyms:

3-oxopalmitoyl-CoA hydrolase activity
3-oxopalmitoyl-CoA-CoA acetyltransferase activity

Branch: molecular function

Genes: HADHB (Hsa)...Hadhb (Mmu)...Hadhb (Rno)...hadhb (Dre)

Genes Annotated with this GO Term (14)

mitochondrial trifunctional protein deficiency 2

Disease

Source: DOID:0060999

Definition: A mitochondrial trifunctional protein deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the HADHB gene the beta subunit of the mitochondrial trifunctional protein, on chromosome 2p23.3.

Genes: Hadhb (Mmu)...hadhb.S (Xla)...HADHB (Hsa)...Hadhb (Rno)...hadhb (Dre)

Gene (9)

mitochondrial fatty acid beta-oxidation multienzyme complex

Gene Ontology

Source: GO:0016507

Synonyms:

fatty acid beta-oxidation multienzyme complex
trifunctional enzyme

Branch: cellular component

Genes: HADHB (Hsa)...Hadhb (Mmu)...Hadhb (Rno)...hadhb (Dre)

Genes Annotated with this GO Term (17)

acetyl-CoA C-acyltransferase activity

Gene Ontology

Source: GO:0003988

Synonyms:

2-keto-acyl thiolase activity
3-ketoacyl coenzyme A thiolase activity

Branch: molecular function

Genes: HADHB (Hsa)...Hadhb (Rno)...hadhb (Dre)...Hadhb (Mmu)

Genes Annotated with this GO Term (45)

acetyl-CoA C-acetyltransferase activity

Gene Ontology

Source: GO:0003985

Synonyms:

acetoacetyl-CoA thiolase activity
acetyl coenzyme A thiolase activity

Branch: molecular function

Genes: HADHB (Hsa)...Hadhb (Rno)...hadhb (Dre)...Hadhb (Mmu)

Genes Annotated with this GO Term (34)

lipid metabolism disorder

Disease

Source: DOID:3146

Definition: An inherited metabolic disorder that involves the creation and degradation of lipids.

Genes: hadhb (Xtr)...Hadhb (Mmu)...HADHB (Hsa)...Hadhb (Rno)...hadhb (Dre)

mitochondrial metabolism disease

Disease

Source: DOID:700

Definition: An inherited metabolic disorder that involves mitochondrial metabolism dysfunction.

Genes: Hadhb (Mmu)...Hadhb (Rno)...hadhb (Dre)...hadhb (Xtr)...HADHB (Hsa)

lncRNA binding

Gene Ontology

Source: GO:0106222

Synonyms:

long noncoding RNA binding

Branch: molecular function

Genes: Hadhb (Mmu)...HADHB (Hsa)...Hadhb (Rno)

Genes Annotated with this GO Term (124)

enoyl-CoA hydratase activity

Gene Ontology

Source: GO:0004300

Synonyms:

(3S)-3-hydroxyacyl-CoA hydro-lyase activity
2-enoyl-CoA hydratase activity

Branch: molecular function

Genes: HADHB (Hsa)

Genes Annotated with this GO Term (57)

mitochondrial nucleoid

Gene Ontology

Source: GO:0042645

Synonyms: Not Available

Branch: cellular component

Genes: Hadhb (Mmu)...Hadhb (Rno)...HADHB (Hsa)

Genes Annotated with this GO Term (200)

3-hydroxyacyl-CoA dehydrogenase activity

Gene Ontology

Source: GO:0003857

Synonyms:

3-oxoacyl-thioester reductase activity
L-3-hydroxyacyl CoA dehydrogenase activity

Branch: molecular function

Genes: HADHB (Hsa)

Genes Annotated with this GO Term (33)

fatty acid beta-oxidation

Gene Ontology

Source: GO:0006635

Synonyms: Not Available

Branch: biological process

Genes: Hadhb (Mmu)...Hadhb (Rno)...hadhb (Dre)...HADHB (Hsa)

Genes Annotated with this GO Term (302)

mitochondrial envelope

Gene Ontology

Source: GO:0005740

Synonyms: Not Available

Branch: cellular component

Genes: HADHB (Hsa)

Genes Annotated with this GO Term (4183)

steatotic liver disease

Disease

Source: DOID:9452

Definition: A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.

Genes: Hadhb (Mmu)...Hadhb (Rno)...hadhb (Dre)...hadhb (Xtr)...HADHB (Hsa)

acyltransferase activity, transferring groups other than amino-acyl groups

Gene Ontology

Source: GO:0016747

Synonyms:

transferase activity, transferring acyl groups other than amino-acyl groups
transferase activity, transferring groups other than amino-acyl groups

Branch: molecular function

Genes: hadhb (Dre)...HADHB (Hsa)

Genes Annotated with this GO Term (1431)

acyltransferase activity

Gene Ontology

Source: GO:0016746

Synonyms:

transferase activity, transferring acyl groups

Branch: molecular function

Genes: hadhb (Dre)...HADHB (Hsa)

Genes Annotated with this GO Term (3870)

gene expression

Gene Ontology

Source: GO:0010467

Synonyms: Not Available

Branch: biological process

Genes: HADHB (Hsa)...Hadhb (Mmu)...Hadhb (Rno)

Genes Annotated with this GO Term (10000)

cellular response to lipopolysaccharide

Gene Ontology

Source: GO:0071222

Synonyms:

cellular response to LPS
cellular response to endotoxin

Branch: biological process

Genes: HADHB (Hsa)...Hadhb (Mmu)...Hadhb (Rno)

Genes Annotated with this GO Term (977)

mitochondrial outer membrane

Gene Ontology

Source: GO:0005741

Synonyms:

mitochondrion outer membrane
outer mitochondrial membrane

Branch: cellular component

Genes: HADHB (Hsa)...Hadhb (Mmu)...Hadhb (Rno)

Genes Annotated with this GO Term (1007)

Alzheimer's disease

Disease

Source: DOID:10652

Definition: A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.

Genes: hadhb (Dre)...hadhb (Xtr)...HADHB (Hsa)...Hadhb (Mmu)...Hadhb (Rno)