Gene

CAP

Species
Drosophila melanogaster
Symbol
CAP
Name
CAP
Synonyms
  • Cap
  • cap
Biotype
protein coding gene
Automated Description
Involved in sensory perception of sound and somatic muscle attachment to chitin-based cuticle. Is expressed in several structures, including adult head; larval muscle cell; sense organ; sensory nervous system primordium; and sensory organ cell.
FB Description
CAP (CAP) encodes a protein that localizes to focal adhesions and associates with proteins that regulate cytoskeletal organization, including the product of Vinc. It regulates the assembly and function of two actin-rich structures: the larval muscle attachment site, and the fly chordotonal organs in the larval body wall and in the adult Johnston's organ.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14167
Stringency:
Additional filters to further constrain the results:
No ortholog matching your filter. Please try a less stringent filter.
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
POSH134839273 of 8  
cindr231939232 of 8  
EndoA326243262 of 8  
drk42 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
abnormal auditory perception | adult stage
abnormal behavior | third instar larval stage
abnormal cell number | embryonic stage
abnormal cell polarity | embryonic stage
abnormal cell shape | embryonic stage
abnormal neuroanatomy | adult stage
adult heart
embryonic cardioblast
embryonic cardioblast | increased number
embryonic/larval heart | embryonic stage
Showing 1 - 10 of 18 rows
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

No mapped variant information available
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
CAP49a
  • CAP[49a]
allele
CAPCA07185
  • CAP[CA07185]
allele
Yes
CAPNP7370
  • CAP[NP7370]
allele
CAPKG00083
  • CAP[KG00083]
  • rexin[KG00083]
allele with one associated variant
insertion
  • intron variant
CAPMI03930
  • CAP[MI03930]
allele with one associated variant
insertion
  • intron variant
CAPe02572
  • CAP[e02572]
allele with one associated variant
insertion
  • intron variant
CAP49e
  • CAP[49e]
  • dCAP[49e]
allele with one associated variant
deletion
  • splice acceptor variant
Yes
CAPMI08454
  • CAP[MI08454]
allele with one associated variant
insertion
  • intron variant
CAPEY21786
  • CAP[EY21786]
allele with one associated variant
insertion
  • intron variant
CAPMI03547
  • CAP[MI03547]
allele with one associated variant
insertion
  • intron variant
Showing 1 - 10 of 1,589 rows
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Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterCAPC.UAS.Tag:MYC
  • UAS
Drosophila melanogasterCAPE.UAS.Tag:MYC
  • UAS
Drosophila melanogasterCAPGD8545
  • UASt
Drosophila melanogasterCAPGL00573
  • UAS
Drosophila melanogasterCAPHM05250
  • UAS
Drosophila melanogasterCAPHMS01551
  • UAS
Drosophila melanogasterCAPKK107936
  • UASt
Drosophila melanogasterCAPNIG.18408R
  • UASt
Drosophila melanogasterCAPNIG.3451R
  • UASt
Drosophila melanogasterCAPRNAi.UAS
  • UAS
Showing 1 - 10 of 15 rows
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Models

No data available

Sequence Details

Transcript: Mode:

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

42 interactor genes based on 81 annotations
CAP molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
arrDrosophila melanogaster
protein
  • pull down
PMID:12711303
protein
ArtsDrosophila melanogaster
protein
  • two hybrid array
PMID:19079254
protein
AxnDrosophila melanogaster
protein
  • pull down
PMID:12385759
protein
AxnDrosophila melanogaster
protein
  • two hybrid
PMID:12385759
protein
AxnDrosophila melanogaster
protein
  • two hybrid
PMID:12711303
protein
bowlDrosophila melanogaster
protein
  • two hybrid
FB:FBrf0235788
protein
bowlDrosophila melanogaster
protein
  • two hybrid
FB:FBrf0235788
protein
byDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CAPDrosophila melanogaster
protein
  • pull down
PMID:12385759
protein
CG1368Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
Showing 1 - 10 of 81 rows
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Genetic Interactions

No data available