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Synonyms: RNF53, early onset breast cancer 1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast cancer 1, BRCC1, BRCA1, DNA repair associated, RING finger protein 53, breast and ovarian cancer susceptibility protein 1, BRCA1/BRCA2-containing complex, subunit 1, breast cancer 1, early onset, IRIS, Fanconi anemia, complementation group S, breast cancer type 1 susceptibility protein, BRCAI, PNCA4, PSCP, truncated BRCA1, BROVCA1, protein phosphatase 1, regulatory subunit 53, breast cancer 1, PPP1R53, FANCS

Source: HGNC:1100

Biotype: protein coding gene

pax2a

(Danio rerio)

Gene

Name: paired box 2a

Synonyms: no isthmus, pax2.1, pax-b, cb378, pax[zf-b], pax2a1, Pax-2, noi, Pax2.1, paxb

Source: ZFIN:ZDB-GENE-990415-8

Biotype: protein coding gene

ss

(Drosophila melanogaster)

Gene

Name: spineless

Synonyms: Ss, SS, ssa, Spineless, CG6993, aristapedia, dAHR, AhR, AHR, spineless-aristapedia

Source: FB:FBgn0003513

Biotype: protein coding gene

sox9a

(Danio rerio)

Gene

Name: SRY-box transcription factor 9a

Synonyms: jellyfish, wu:fj17b12, zgc:111921, jef

Source: ZFIN:ZDB-GENE-001103-1

Biotype: protein coding gene

BRCA2

(Homo sapiens)

Gene

Name: BRCA2 DNA repair associated

Synonyms: truncated breast and ovarian cancer susceptibility protein 2, DNA repair-associated BRCA2, FAD1, truncated DNA repair-associated BRCA2, BRCC2, GLM3, BRCA2, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 2, breast cancer type 2 susceptibility protein, breast cancer 2, early onset, breast cancer 2 tumor suppressor, breast and ovarian cancer susceptibility gene, early onset, PNCA2, truncated BRCA2 DNA repair associated, fanconi anemia group D1 protein, truncated breast cancer 2, FAD, mutant BRCA2, breast cancer susceptibility protein BRCA2, FANCB, FANCD, breast and ovarian cancer susceptibility protein 2, mutant DNA repair-associated protein 2, FANCD1, BROVCA2, XRCC11, breast cancer 2, FACD

Source: HGNC:1101

Biotype: protein coding gene

EGFR

(Homo sapiens)

Gene

Name: epidermal growth factor receptor

Synonyms: PIG61, NNCIS, receptor tyrosine-protein kinase erbB-1, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), erythroblastic leukemia viral (v-erb-b) oncogene homolog, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, NISBD2, HER1

Source: HGNC:3236

Biotype: protein coding gene

TNF

(Homo sapiens)

Gene

Name: tumor necrosis factor

Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin

Source: HGNC:11892

Biotype: protein coding gene

SSN8

(Saccharomyces cerevisiae)

Gene

Name: Suppressor of SNf1

Synonyms: UME3, RYE2, SRB11, CNC1, CycC, NUT9, YNL025C, GIG3

Source: SGD:S000004970

Biotype: protein coding gene

Allele/Variant (16)

Sox7

(Mus musculus)

Gene

Name: SRY (sex determining region Y)-box 7

Synonyms: Not Available

Source: MGI:98369

Biotype: protein coding gene

SNCA

(Homo sapiens)

Gene

Name: synuclein alpha

Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1

Source: HGNC:11138

Biotype: protein coding gene

ERCC5

(Homo sapiens)

Gene

Name: ERCC excision repair 5, endonuclease

Synonyms: xeroderma pigmentosum, complementation group G, ERCC5-201, UVDR, ERCM2, xeroderma pigmentosum group G-complementing protein, XPG, COFS3, excision repair protein, excision repair cross-complementing rodent repair deficiency, complementation group 5, DNA repair protein complementing XP-G cells, excision repair cross-complementation group 5, XPG-complementing protein, DNA excision repair protein ERCC-5, XPGC, xeroderma pigmentosum complementation group G protein

Source: HGNC:3437

Biotype: protein coding gene

Tnf

(Mus musculus)

Gene

Name: tumor necrosis factor

Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF

Source: MGI:104798

Biotype: protein coding gene

BCL2

(Homo sapiens)

Gene

Name: BCL2 apoptosis regulator

Synonyms: Bcl-2, protein phosphatase 1, regulatory subunit 50, Bcl-2a, B-cell CLL/lymphoma 2, PPP1R50, Bcl-2ß, apoptosis regulator Bcl-2, b-cell leukemia/lymphoma 2, BCL2, apoptosis regulator

Source: HGNC:990

Biotype: protein coding gene

SIRT1

(Homo sapiens)

Gene

Name: sirtuin 1

Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, regulatory protein SIR2 homolog 1, hSIRT1, hSIR2, sirtuin type 1, NAD-dependent deacetylase sirtuin-1

Source: HGNC:14929

Biotype: protein coding gene

HSF1

(Saccharomyces cerevisiae)

Gene

Name: Heat Shock transcription Factor

Synonyms: YGL073W, EXA3, MAS3

Source: SGD:S000003041

Biotype: protein coding gene

MTOR

(Homo sapiens)

Gene

Name: mechanistic target of rapamycin kinase

Synonyms: mechanistic target of rapamycin, rapamycin target protein 1, rapamycin and FKBP12 target 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FKBP12-rapamycin complex-associated protein 1, FRAP2, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, SKS, FRAP, serine/threonine-protein kinase mTOR, RAPT1, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2

Source: HGNC:3942

Biotype: protein coding gene

Evx1

(Mus musculus)

Gene

Name: even-skipped homeobox 1

Synonyms: Evx-1, even skipped homeotic gene 1 homolog

Source: MGI:95461

Biotype: protein coding gene

pax6a

(Danio rerio)

Gene

Name: paired box 6a

Synonyms: paxzfa, fc20e07, Pax6.1, pax-a, wu:fc20e07, pax[zf-a], zfpax-6b, zfpax-6a, etID309716.25, pax6, cb280

Source: ZFIN:ZDB-GENE-990415-200

Biotype: protein coding gene

Apex2

(Mus musculus)

Gene

Name: apurinic/apyrimidinic endonuclease 2

Synonyms: C430040P13Rik, RIKEN cDNA C430040P13 gene, Ape2

Source: MGI:1924872

Biotype: protein coding gene

RECQL

(Homo sapiens)

Gene

Name: RecQ like helicase

Synonyms: RecQ protein-like (DNA helicase Q1-like), RecQ1, recQ protein-like 1, DNA helicase, RecQ-like type 1, ATP-dependent DNA helicase Q1, DNA helicase Q1-like, RECON, DNA 3'-5' helicase Q1, DNA-dependent ATPase Q1, RecQ helicase-like, RECQL1

Source: HGNC:9948

Biotype: protein coding gene

MIP1

(Saccharomyces cerevisiae)

Gene

Name: MItochondrial DNA Polymerase

Synonyms: YOR330C

Source: SGD:S000005857

Biotype: protein coding gene

MRE11

(Homo sapiens)

Gene

Name: MRE11 homolog, double strand break repair nuclease

Synonyms: HNGS1, double-strand break repair protein MRE11A, MRE11 homolog A, DNA recombination and repair protein, MRE11A, MRE11B, endo/exonuclease Mre11, meiotic recombination 11 homolog A, double-strand break repair protein MRE11, MRE11 meiotic recombination 11-like protein A, MRE11 homolog A, double strand break repair nuclease, MRE11 meiotic recombination 11 homolog A, ATLD, AT-like disease, MRE11 homolog 1, MRE11 double strand break repair nuclease A, MRE11 homolog, double strand break repair nuclease A, meiotic recombination 11 homolog 1

Source: HGNC:7230

Biotype: protein coding gene

SGS1

(Saccharomyces cerevisiae)

Gene

Name: Slow Growth Suppressor

Synonyms: YMR190C

Source: SGD:S000004802

Biotype: protein coding gene

daf-16

(Caenorhabditis elegans)

Gene

Name: abnormal DAuer Formation 16

Synonyms: daf-17, R13H8.1, CELE_R13H8.1

Source: WB:WBGene00000912

Biotype: protein coding gene

SARNP

(Homo sapiens)

Gene

Name: SAP domain containing ribonucleoprotein

Synonyms: THO1, CIP29, HSPC316, hepatocellular carcinoma 1, HCC1, proliferation associated cytokine-inducible protein CIP29, SAP domain-containing ribonucleoprotein, proliferation-associated cytokine-inducible protein CIP29, nuclear protein Hcc-1, cytokine induced protein 29 kDa, MGC14726, cytokine-induced protein of 29 kDa

Source: HGNC:24432

Biotype: protein coding gene

Allele/Variant (10)

Emx1

(Mus musculus)

Gene

Name: empty spiracles homeobox 1

Synonyms: RGD1564002

Source: MGI:95387

Biotype: protein coding gene

ALX3

(Homo sapiens)

Gene

Name: ALX homeobox 3

Synonyms: homeobox protein aristaless-like 3, FND1, MGC138212, aristaless-like homeobox 3, frontonasal dysplasia, proline-rich transcription factor ALX3, FND, MGC141988

Source: HGNC:449

Biotype: protein coding gene

ACE2

(Saccharomyces cerevisiae)

Gene

Name: Activator of CUP1 Expression

Synonyms: YLR131C

Source: SGD:S000004121

Biotype: protein coding gene

Allele/Variant (32)

MCM1

(Saccharomyces cerevisiae)

Gene

Name: MiniChromosome Maintenance

Synonyms: FUN80, YMR043W

Source: SGD:S000004646

Biotype: protein coding gene

MECP2

(Homo sapiens)

Gene

Name: methyl-CpG binding protein 2

Synonyms: meCp-2 protein, RS, DKFZp686A24160, mutant methyl CpG binding protein 2 variant 1, PPMX, AUTSX3, MRXSL, mental retardation, X-linked 16, RTS, mental retardation, X-linked 79, RTT, MRXS13, testis tissue sperm-binding protein Li 41a, MRX79, mutant methyl CpG binding protein 2 transcript 1, methyl-CpG-binding protein 2, MRX16, methyl CpG binding protein 2, mutant methyl CpG binding protein 2

Source: HGNC:6990

Biotype: protein coding gene

THAP12

(Homo sapiens)

Gene

Name: THAP domain containing 12

Synonyms: inhibitor of protein kinase PKR, THAP domain-containing protein 0, P52rIPK, p58IPK-interacting protein, 52 kDa repressor of the inhibitor of the protein kinase, MGC102750, THAP0, 58 kDa interferon-induced protein kinase-interacting protein, THAP domain-containing protein 12, testicular tissue protein Li 133, PRKRIR, death-associated protein 4, protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor), DAP4

Source: HGNC:9440

Biotype: protein coding gene

Allele/Variant (5)

Brca1

(Mus musculus)

Gene

Name: breast cancer 1, early onset

Synonyms: BRCA-1

Source: MGI:104537

Biotype: protein coding gene

fkh-2

(Caenorhabditis elegans)

Gene

Name: ForKHead transcription factor family 2

Synonyms: T14G12.4, CELE_T14G12.4

Source: WB:WBGene00001434

Biotype: protein coding gene

Brca2

(Mus musculus)

Gene

Name: breast cancer 2, early onset

Synonyms: expressed sequence AW045498, AW045498, Fancd1, expressed sequence AI256696, AI256696, RAB163

Source: MGI:109337

Biotype: protein coding gene

Rag2

(Mus musculus)

Gene

Name: recombination activating gene 2

Synonyms: Rag-2

Source: MGI:97849

Biotype: protein coding gene

Ezh2

(Mus musculus)

Gene

Name: enhancer of zeste 2 polycomb repressive complex 2 subunit

Synonyms: enhancer of zeste homolog (Drosophila), Enx-1, Enx1h, KMT6

Source: MGI:107940

Biotype: protein coding gene

Sry

(Mus musculus)

Gene

Name: sex determining region of Chr Y

Synonyms: testis determining factor, SRYGENE, Tdf, Tdy, testis determining-Y, Sry3B

Source: MGI:98660

Biotype: protein coding gene

Antp

(Drosophila melanogaster)

Gene

Name: Antennapedia

Synonyms: ANTC, antp, ANT-C, Nasobemia, Ant, Scx, Antp1, Antenapedia, DMANTPE1, Antp P1, Antp P2, DmAntp, Sex combs extra, CG1028, Aus, BG:DS07700.1, Ns, Sex comb extra, Hu, antennapedia, AntP1, Humeral, ANT-P, DRO15DC96Z, Antennapaedia, Antennapedia P2, AntP, Antennapedia P1, l(3)84Ba, ANTP, 3.4, Dm-Antennapedia, Atennapedia

Source: FB:FBgn0260642

Biotype: protein coding gene

Sox14

(Drosophila melanogaster)

Gene

Name: Sox box protein 14

Synonyms: Dsox-14, CG17263, SOXC, Sox-14, DSox14, DSox-14, sox14, SOX60B, SOX14, sox box protein 14, DSox60B, CG3090

Source: FB:FBgn0005612

Biotype: protein coding gene

Brca1

(Rattus norvegicus)

Gene

Name: BRCA1, DNA repair associated

Synonyms: BRCA-1, breast cancer 1, early onset, breast cancer type 1 susceptibility protein homolog, breast cancer 1, RING-type E3 ubiquitin transferase BRCA1

Source: RGD:2218

Biotype: protein coding gene

ACTB

(Homo sapiens)

Gene

Name: actin beta

Synonyms: actin, cytoplasmic 1, DDS1, beta cytoskeletal actin, actin, beta, CSMH, PS1TP5BP1, BNS, PS1TP5-binding protein 1, BKRNS, I(2)-actin, BRWS1, THC8

Source: HGNC:132

Biotype: protein coding gene

Foxp2

(Mus musculus)

Gene

Name: forkhead box P2

Synonyms: 2810043D05Rik, RGD1559697, RIKEN cDNA 2810043D05 gene, expressed sequence AI449000, AI449000, D0Kist7, DNA segment, KIST 7

Source: MGI:2148705

Biotype: protein coding gene

HAC1

(Saccharomyces cerevisiae)

Gene

Name: Homologous to Atf/Creb1

Synonyms: ERN4, YFL031W, IRE15

Source: SGD:S000001863

Biotype: protein coding gene

Allele/Variant (38)

NLRP3

(Homo sapiens)

Gene

Name: NLR family pyrin domain containing 3

Synonyms: caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, cryopyrin, NACHT, LRR and PYD domains - containing protein 3, CIAS1, deafness, autosomal dominant 34, NACHT, LRR and PYD domains-containing protein 3, cold autoinflammatory syndrome 1, FCAS, cryopyrin, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, AII/AVP receptor-like, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3, FCAS1, AGTAVPRL, DFNA34, AII, CLR1.1, MWS, PYPAF1, AII/AVP, NACHT, LRR and PYD containing protein 3, NLR family, pyrin domain containing 3, FLJ95925, NALP3, C1orf7, angiotensin/vasopressin receptor AII/AVP-like, FCU, AVP, KEFH

Source: HGNC:16400

Biotype: protein coding gene

TP53BP1

(Homo sapiens)

Gene

Name: tumor protein p53 binding protein 1

Synonyms: p53-binding protein 1, FLJ41424, tumor protein p53-binding protein, 1, TDRD30, p53BP1, MGC138366, 53BP1, p202, tumor protein 53-binding protein, 1, TP53-binding protein 1, TP53, tumor suppressor p53-binding protein 1

Source: HGNC:11999

Biotype: protein coding gene