Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: DNA duplex unwinding
RECQL
(Homo sapiens)Gene
Name: RecQ like helicase
Synonyms: RecQ protein-like (DNA helicase Q1-like), RecQ1, recQ protein-like 1, DNA helicase, RecQ-like type 1, ATP-dependent DNA helicase Q1, DNA helicase Q1-like, RECON, DNA 3'-5' helicase Q1, DNA-dependent ATPase Q1, RecQ helicase-like, RECQL1
Source: HGNC:9948
Biotype: protein coding gene
MRE11
(Homo sapiens)Gene
Name: MRE11 homolog, double strand break repair nuclease
Synonyms: HNGS1, double-strand break repair protein MRE11A, MRE11 homolog A, DNA recombination and repair protein, MRE11A, MRE11B, endo/exonuclease Mre11, meiotic recombination 11 homolog A, double-strand break repair protein MRE11, MRE11 meiotic recombination 11-like protein A, MRE11 homolog A, double strand break repair nuclease, MRE11 meiotic recombination 11 homolog A, ATLD, AT-like disease, MRE11 homolog 1, MRE11 double strand break repair nuclease A, MRE11 homolog, double strand break repair nuclease A, meiotic recombination 11 homolog 1
Source: HGNC:7230
Biotype: protein coding gene
SGS1
(Saccharomyces cerevisiae)Gene
Name: Slow Growth Suppressor
Synonyms: YMR190C
Source: SGD:S000004802
Biotype: protein coding gene
ERCC2
(Homo sapiens)Gene
Name: ERCC excision repair 2, TFIIH core complex helicase subunit
Synonyms: general transcription and DNA repair factor IIH helicase subunit XPD, TTD, TFIIH basal transcription factor complex 80 kDa subunit, TTD1, TFIIH basal transcription factor complex helicase subunit, COFS2, DNA 5'-3' helicase XPD, XPD, EM9, excision repair cross-complementing rodent repair deficiency, complementation group 2, xeroderma pigmentosum complementary group D, xeroderma pigmentosum group D-complementing protein, BTF2 p80, basic transcription factor 2 80 kDa subunit, trichothiodystrophy, MGC102762, MGC126218, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex helicase XPB subunit, MGC126219, excision repair cross-complementation group 2, TFIIH basal transcription factor complex helicase XPD subunit, TFIIH subunit XPD, TFIIH, CXPD, TFIIH p80, TFIIH 80 kDa subunit, DNA excision repair protein ERCC-2
Source: HGNC:3434
Biotype: protein coding gene
DNA2
(Homo sapiens)Gene
Name: DNA replication helicase/nuclease 2
Synonyms: RTS4, MGC133297, DNA replication helicase 2 homolog, PEOA6, DNA2 (DNA replication helicase, yeast, homolog)-like, DNA2 DNA replication helicase 2-like, KIAA0083, FLJ10063, DNA replication ATP-dependent helicase/nuclease DNA2, DNA2L, DNA2-like helicase, SCKL8, hDNA2, DNA replication ATP-dependent helicase-like homolog
Source: HGNC:2939
Biotype: protein coding gene
WRNIP1
(Homo sapiens)Gene
Name: WRN helicase interacting protein 1
Synonyms: WHIP, CFAP93, RP11-420G6.2, putative helicase RUVBL, ATPase WRNIP1, Werner helicase interacting protein 1, FAP93, Werner helicase-interacting protein 1, bA420G6.2, FLJ22526
Source: HGNC:20876
Biotype: protein coding gene
PIF1
(Homo sapiens)Gene
Name: PIF1 5'-to-3' DNA helicase
Synonyms: ATP-dependent DNA helicase PIF1, DNA helicase PIF1, PIF1/RRM3 DNA helicase-like protein, petite integration frequency 1, C15orf20, PIF1 5'-to-3' DNA helicase homolog, chromosome 15 open reading frame 20, DNA helicase homolog PIF1, PIF1 DNA helicase, DNA repair and recombination helicase PIF1, PIF
Source: HGNC:26220
Biotype: protein coding gene
RAD54L
(Homo sapiens)Gene
Name: RAD54 like
Synonyms: RAD54-like (S. cerevisiae), RAD54 homolog, hRAD54, HR54, DNA repair and recombination protein RAD54-like, hHR54, RAD54 like (S. cerevisiae), RAD54A
Source: HGNC:9826
Biotype: protein coding gene
DDX3X
(Homo sapiens)Gene
Name: DEAD-box helicase 3 X-linked
Synonyms: DEAD box, X isoform, CAP-Rf, DEAD box protein 3, X-chromosomal, DDX3, DDX14, HLP2, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked, ATP-dependent RNA helicase DDX3X, MRX102, helicase-like protein 2, DEAD-box helicase 3, X-linked, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked, helicase like protein 2, DBX, DEAD/H box-3, MRXSSB
Source: HGNC:2745
Biotype: protein coding gene
IGHMBP2
(Homo sapiens)Gene
Name: immunoglobulin mu DNA binding protein 2
Synonyms: zinc finger, AN1-type domain 7, ZFAND7, GF-1, ATP-dependent helicase IGHMBP2, DNA-binding protein SMUBP-2, SMARD1, HCSA, cardiac transcription factor 1, FLJ41171, HMN6, CATF1, SMUBP2, HMNR1, FLJ34220, immunoglobulin mu-binding protein 2, immunoglobulin mu binding protein 2, glial factor 1, CMT2S
Source: HGNC:5542
Biotype: protein coding gene
SETX
(Homo sapiens)Gene
Name: senataxin
Synonyms: AOA2, SCAR1, SCAN2, DKFZp781B151, FLJ43459, ALS4, STEX, Sen1, SEN1 homolog, FLJ12840, KIAA0625, bA479K20.2, amyotrophic lateral sclerosis 4, spinocerebellar ataxia, recessive, non-Friedreich type 1, probable helicase senataxin
Source: HGNC:445
Biotype: protein coding gene
RAD50
(Homo sapiens)Gene
Name: RAD50 double strand break repair protein
Synonyms: hRad50, DNA repair protein RAD50, RAD502, RAD50-2, RAD50 homolog, NBSLD
Source: HGNC:9816
Biotype: protein coding gene
Ddx1
(Mus musculus)Gene
Name: DEAD box helicase 1
Synonyms: expressed sequence AA409185, AA409185, DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
Source: MGI:2144727
Biotype: protein coding gene
G3BP1
(Homo sapiens)Gene
Name: G3BP stress granule assembly factor 1
Synonyms: MGC111040, DNA helicase VIII, Ras-GTPase-activating protein SH3-domain-binding protein, GAP SH3 domain-binding protein 1, ATP-dependent DNA helicase VIII, G3BP, ras GTPase-activating protein-binding protein 1, G3BP-1, GTPase activating protein (SH3 domain) binding protein 1, GAP binding protein, RasGAP-associated endoribonuclease G3BP, HDH-VIII
Source: HGNC:30292
Biotype: protein coding gene
Pura
(Mus musculus)Gene
Name: purine rich element binding protein A
Synonyms: Pur-alpha, ssCRE-BP, Pur alpha, CAGER-1
Source: MGI:103079
Biotype: protein coding gene
RAD5
(Saccharomyces cerevisiae)Gene
Name: RADiation sensitive
Synonyms: YLR032W, SNM2, REV2
Source: SGD:S000004022
Biotype: protein coding gene
WRN
(Homo sapiens)Gene
Name: WRN RecQ like helicase
Synonyms: RECQ3, RECQL3, Werner syndrome RecQ like helicase, bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, Werner syndrome, RecQ helicase-like, recQ protein-like 2, exonuclease WRN, DNA helicase, RecQ-like type 3, DKFZp686C2056, RECQL2, Werner syndrome ATP-dependent helicase
Source: HGNC:12791
Biotype: protein coding gene
BLM
(Homo sapiens)Gene
Name: BLM RecQ like helicase
Synonyms: MGRISCE1, Bloom syndrome RecQ like helicase, MGC131620, recQ-like DNA helicase BLM, Bloom syndrome, RecQ helicase-like, MGC126616, RECQL3, BS, RECQ2, Bloom syndrome protein, recQ protein-like 3, DNA helicase, RecQ-like type 2, MGC131618, DNA 3'-5' helicase BLM, RECQL2
Source: HGNC:1058
Biotype: protein coding gene
RAD3
(Saccharomyces cerevisiae)Gene
Name: RADiation sensitive
Synonyms: REM1, YER171W
Source: SGD:S000000973
Biotype: protein coding gene
SWR1
(Saccharomyces cerevisiae)Gene
Name: SWi2/snf2-Related
Synonyms: YDR334W
Source: SGD:S000002742
Biotype: protein coding gene
INO80
(Saccharomyces cerevisiae)Gene
Name: INOsitol requiring
Synonyms: YGL150C
Source: SGD:S000003118
Biotype: protein coding gene
HRQ1
(Saccharomyces cerevisiae)Gene
Name: Homologous to RecQ protein
Synonyms: YDR291W
Source: SGD:S000002699
Biotype: protein coding gene
Hfm1
(Mus musculus)Gene
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: gene model 1046, (NCBI), Sec63d1, SEC63 domain containing 1, LOC381663, A330009G12Rik, Gm1046, RIKEN cDNA A330009G12 gene, Mer3
Source: MGI:3036246
Biotype: protein coding gene
MCM2
(Homo sapiens)Gene
Name: minichromosome maintenance complex component 2
Synonyms: D3S3194, MGC10606, DFNA70, cdc19, BM28, cyclin-like 1, KIAA0030, mcm2 minichromosome maintenance deficient 2, mitotin (s. cerevisiae), DNA replication licensing factor MCM2, MITOTIN, MCM2 minichromosome maintenance deficient 2, mitotin, CDCL1, CCNL1, minichromosome maintenance protein 2 homolog, cell devision cycle-like 1, minichromosome maintenance deficient 2 (mitotin), nuclear protein BM28
Source: HGNC:6944
Biotype: protein coding gene
CHD7
(Homo sapiens)Gene
Name: chromodomain helicase DNA binding protein 7
Synonyms: chromodomain-helicase-DNA-binding protein 7, CHARGE association, KIAA1416, HH5, FLJ20361, chromodomain helicase DNA binding protein 7 isoform CRA_e, CHD-7, IS3, CRG, FLJ20357, KAL5, ATP-dependent helicase CHD7
Source: HGNC:20626
Biotype: protein coding gene
Recql4
(Mus musculus)Gene
Name: RecQ protein-like 4
Synonyms: Not Available
Source: MGI:1931028
Biotype: protein coding gene
SMARCAD1
(Homo sapiens)Gene
Name: SNF2 related chromatin remodeling ATPase with DExD box 1
Synonyms: SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1, HEL1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, ATP-dependent helicase 1, KIAA1122, ADERM, TYS, DKFZp762K2015, hHEL1, HRZ, ETL1, BASNS, sclerotylosis
Source: HGNC:18398
Biotype: protein coding gene
RAD51
(Homo sapiens)Gene
Name: RAD51 recombinase
Synonyms: recombination protein A, RAD51 homolog A, RecA-like protein, RAD51 homolog (RecA homolog, E. coli), MRMV2, RecA, E. coli, homolog of, HsRad51, HsT16930, BRCC5, BRCA1/BRCA2-containing complex, subunit 5, RAD51A, DNA repair protein RAD51 homolog 1, HRAD51, RECA, FANCR, truncated RAD51
Source: HGNC:9817
Biotype: protein coding gene
ERCC3
(Homo sapiens)Gene
Name: ERCC excision repair 3, TFIIH core complex helicase subunit
Synonyms: GTF2H, TFIIH p89, excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing), xeroderma pigmentosum, complementation group B, TTD2, XPB, xeroderma pigmentosum group B-complementing protein, general transcription and DNA repair factor IIH helicase subunit XPB, BTF2 p89, DNA repair protein complementing XP-B cells, excision repair cross-complementing rodent repair deficiency, complementation group 3, TFIIH 89 kDa subunit, RAD25, BTF2, Ssl2, general transcription and DNA repair factor IIH helicase/translocase subunit XPB, TFIIH basal transcription factor complex helicase XPB subunit, DNA 3'-5' helicase/translocase XPB, excision repair cross-complementation group 3, basic transcription factor 2 89 kDa subunit, TFIIH basal transcription factor complex 89 kDa subunit, xeroderma pigmentosum group B complementing, TFIIH, TFIIH subunit XPB, DNA excision repair protein ERCC-3, DNA repair helicase
Source: HGNC:3435
Biotype: protein coding gene
DNA2
(Saccharomyces cerevisiae)Gene
Name: DNA synthesis defective
Synonyms: YHR164C, WEB2
Source: SGD:S000001207
Biotype: protein coding gene
RAD50
(Saccharomyces cerevisiae)Gene
Name: RADiation sensitive
Synonyms: YNL250W
Source: SGD:S000005194
Biotype: protein coding gene
HELB
(Homo sapiens)Gene
Name: DNA helicase B
Synonyms: helicase B, hDHB, helicase (DNA) B, DHB
Source: HGNC:17196
Biotype: protein coding gene
chd-3
(Caenorhabditis elegans)Gene
Name: Chromodomain and Helicase Domain protein 3
Synonyms: T14G8.1, CELE_T14G8.1
Source: WB:WBGene00000482
Biotype: protein coding gene
Upf1
(Drosophila melanogaster)Gene
Name: Upf1 RNA helicase
Synonyms: Dm-Upf1, upf1, up-frameshift suppressor 1, UPF1, dUPF1, smg-2, Upf1p, CG1559, Upf1, DmUpf1
Source: FB:FBgn0030354
Biotype: protein coding gene
MCM6
(Saccharomyces cerevisiae)Gene
Name: MiniChromosome Maintenance
Synonyms: YGL201C
Source: SGD:S000003169
Biotype: protein coding gene
Smarcad1
(Mus musculus)Gene
Name: SNF2 related chromatin remodeling ATPase with DExD box 1
Synonyms: AW226546, expressed sequence AW226546, mKIAA1122, Etl1, AV081750, DNA segment, Chr 6, Pasteur Institute 1, D6Pas1, enhancer trap locus 1, expressed sequence AV081750
Source: MGI:95453
Biotype: protein coding gene
ruvb-1
(Caenorhabditis elegans)Gene
Name: RUVB (recombination protein) homolog 1
Synonyms: C27H6.2, CELE_C27H6.2
Source: WB:WBGene00007784
Biotype: protein coding gene
Mcm2
(Mus musculus)Gene
Name: minichromosome maintenance complex component 2
Synonyms: AW476101, CDCL1, expressed sequence AW476101, mini chromosome maintenance deficient 2 (S. cerevisiae), AA959861, expressed sequence AA959861, BM28, Mcmd2, mKIAA0030
Source: MGI:105380
Biotype: protein coding gene
FUN30
(Saccharomyces cerevisiae)Gene
Name: Function Unknown Now
Synonyms: YAL019W
Source: SGD:S000000017
Biotype: protein coding gene
RFA1
(Saccharomyces cerevisiae)Gene
Name: Replication Factor A
Synonyms: BUF2, RPA70, FUN3, RPA1, YAR007C
Source: SGD:S000000065
Biotype: protein coding gene
SEN1
(Saccharomyces cerevisiae)Gene
Name: Splicing ENdonuclease
Synonyms: CIK3, YLR430W, NRD2
Source: SGD:S000004422
Biotype: protein coding gene
Ascc3
(Mus musculus)Gene
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: BC023451, helicase, ATP binding 1, RIKEN cDNA B630009I04 gene, Helic1, B630009I04Rik, cDNA sequence BC023451, ASC1p200
Source: MGI:1925237
Biotype: protein coding gene
NBN
(Homo sapiens)Gene
Name: nibrin
Synonyms: ATV, hNbs1, p95 protein of the MRE11/RAD50 complex, AT-V2, Nijmegen breakage syndrome 1 (nibrin), P95, AT-V1, FLJ10155, NBS1, nijmegen breakage syndrome protein 1, cell cycle regulatory protein p95, NBS, MGC87362
Source: HGNC:7652
Biotype: protein coding gene
Dsp1
(Drosophila melanogaster)Gene
Name: Dorsal switch protein 1
Synonyms: hmg, HMGB1, DSP1, Hmg14B, Structure specific recognition protein 2, Hmg14D, Ssrp2, Dorsal switch protein-1, HMGD1, Dorsal Switch Protein 1, CG12223, ssrp2, dsp1
Source: FB:FBgn0278608
Biotype: protein coding gene
STH1
(Saccharomyces cerevisiae)Gene
Name: SNF Two Homolog
Synonyms: NPS1, YIL126W
Source: SGD:S000001388
Biotype: protein coding gene
Rad51
(Mus musculus)Gene
Name: RAD51 recombinase
Synonyms: AV304093, expressed sequence AV304093, Rad51a, RAD51A homolog (S. cerevisiae), Reca, RGD1563603, recombination and repair of radiation damage, RAD51 homolog
Source: MGI:97890
Biotype: protein coding gene
CHD3
(Homo sapiens)Gene
Name: chromodomain helicase DNA binding protein 3
Synonyms: SNIBCPS, zinc finger helicase, zinc-finger helicase (Snf2-like), mi-2 autoantigen 240 kDa protein, hZFH, CHD-3, ATP-dependent helicase CHD3, Mi2-ALPHA, chromodomain-helicase-DNA-binding protein 3, Mi-2a, ZFH
Source: HGNC:1918
Biotype: protein coding gene
RECQL4
(Homo sapiens)Gene
Name: RecQ like helicase 4
Synonyms: RECQ4, ATP-dependent DNA helicase Q4, DNA helicase, RecQ-like, type 4, DNA 3'-5' helicase RecQ4, DNA helicase, RecQ-like type 4, RecQ helicase-like 4, RecQ protein-like 4
Source: HGNC:9949
Biotype: protein coding gene
SRS2
(Saccharomyces cerevisiae)Gene
Name: Suppressor of Rad Six
Synonyms: RADH, HPR5, RADH1, YJL092W
Source: SGD:S000003628
Biotype: protein coding gene
MCM10
(Saccharomyces cerevisiae)Gene
Name: MiniChromosome Maintenance
Synonyms: YIL150C, DNA43
Source: SGD:S000001412
Biotype: protein coding gene