Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: negative regulation of T cell proliferation
Pten
(Mus musculus)Gene
Name: phosphatase and tensin homolog
Synonyms: B430203M17Rik, RIKEN cDNA B430203M17 gene, expressed sequence AI463227, RIKEN cDNA 2310035O07 gene, TEP1, Mmac, A130070J02Rik, MMAC1, AI463227, 2310035O07Rik, RIKEN cDNA A130070J02 gene
Source: MGI:109583
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Bmp4
(Mus musculus)Gene
Name: bone morphogenetic protein 4
Synonyms: Bmp2b, bone morphogenetic protein 2b, BOMPR4A, Bmp2b-1, Bmp-4, bone morphogenetic protein 2b 1, Bmp2b1
Source: MGI:88180
Biotype: protein coding gene
PTEN
(Homo sapiens)Gene
Name: phosphatase and tensin homolog
Synonyms: MHAM, DEC, PTENepsilon, 10q23del, phosphatase and tensin-like protein, PTEN1, mitochondrial PTENalpha, GLM2, PTEN variant PTEN-K267Rfs*9, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, CWS1, mutated in multiple advanced cancers 1, MMAC1, PTEN variant PTEN-L247*, PTEN variant PTEN-R234Afs*11, mitochondrial phosphatase and tensin protein alpha, TEP1, PTENgama, inositol polyphosphate 3-phosphatase, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, BZS, PTENbeta, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MGC11227
Source: HGNC:9588
Biotype: protein coding gene
Tgfb1
(Mus musculus)Gene
Name: transforming growth factor, beta 1
Synonyms: Tgfb-1, TGF-beta 1, Tgfb, TGFbeta1, TGF-beta1
Source: MGI:98725
Biotype: protein coding gene
HLA-DRB1
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 1
Synonyms: MHC class II HLA-DRw10-beta, HLA-DRB1*, leucocyte antigen DRB1, DW2.2/DR2.2, FLJ76359, HLA-DR-beta 1, leucocyte antigen DR beta 1 chain, MHC class II antigen, major histocompatibility complex, class II, DR beta 1 precursor, DRw8, SS1, DR16, DR-8, MHC class II HLA-DR beta 1 chain, lymphocyte antigen DRB1, DRB1, DR-16, HLA class II histocompatibility antigen, DR-1 beta chain, DR1, MHC class II antigen HLA-DR13, DR5, FLJ75017, HLA class II antigen beta chain, DR8, DRw11, DRw10, MHC class II HLA-DR-beta cell surface glycoprotein, human leucocyte antigen DRB1, HLA-DR1B, HLA-DRB
Source: HGNC:4948
Biotype: protein coding gene
IL10
(Homo sapiens)Gene
Name: interleukin 10
Synonyms: CSIF, MGC126450, MGC126451, TGIF, GVHDS, IL10A, T-cell growth inhibitory factor, cytokine synthesis inhibitory factor, interleukin-10, IL-10
Source: HGNC:5962
Biotype: protein coding gene
BMP4
(Homo sapiens)Gene
Name: bone morphogenetic protein 4
Synonyms: MCOPS6, bone morphogenetic protein 2B, bone morphogenetic protein 4 preproprotein, BMP2B, OFC11, BMP-2B, BMP-4, ZYME, BMP2B1
Source: HGNC:1071
Biotype: protein coding gene
H2-Aa
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen A, alpha
Synonyms: BA1, I-Aalpha, histocompatibility 2, class II antigen A alpha, H-2Aa, A alpha, Ia1, Aalpha, I region-associated antigen 1, Ia-1
Source: MGI:95895
Biotype: protein coding gene
Casp3
(Mus musculus)Gene
Name: caspase 3
Synonyms: RIKEN cDNA A830040C14 gene, Apopain, melody, CC3, A830040C14Rik, Yama, AC-3, CPP32, mldy, CPP32-beta, Lice, Caspase-3
Source: MGI:107739
Biotype: protein coding gene
ERBB2
(Homo sapiens)Gene
Name: erb-b2 receptor tyrosine kinase 2
Synonyms: tyrosine kinase-type cell surface receptor HER2, proto-oncogene c-ErbB-2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2, c-ERB2, HER-2, receptor tyrosine-protein kinase erbB-2, metastatic lymph node gene 19 protein, neuro/glioblastoma derived oncogene homolog, v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2, p185(erbB2), neuroblastoma/glioblastoma derived oncogene homolog, c-erb B2/neu protein, p185erbB2, MLN-19, MLN 19, CD340, VSCN2, human epidermal growth factor receptor 2, TKR1, NGL, proto-oncogene Neu, c-ERB-2, HER-2/neu, herstatin, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog), HER2, NEU
Source: HGNC:3430
Biotype: protein coding gene
Foxp3
(Mus musculus)Gene
Name: forkhead box P3
Synonyms: RGD1562112, sf, scurfy, scurfin, JM2
Source: MGI:1891436
Biotype: protein coding gene
Cd24a
(Mus musculus)Gene
Name: CD24a antigen
Synonyms: nectadrin, heat stable antigen, lymphocyte antigen 52, HSA, cluster of differentiation 24, Ly-52
Source: MGI:88323
Biotype: protein coding gene
SHH
(Homo sapiens)Gene
Name: sonic hedgehog signaling molecule
Synonyms: HLP3, HPE3, sonic hedgehog, TPT, ShhNC, sonic hedgehog homolog, HHG1, MCOPCB5, SMMCI, sonic hedgehog protein, shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, TPTPS
Source: HGNC:10848
Biotype: protein coding gene
CDKN2A
(Homo sapiens)Gene
Name: cyclin dependent kinase inhibitor 2A
Synonyms: MTS1, cyclin-dependent kinase inhibitor 2A, isoform 4, cyclin-dependent kinase inhibitor 2A, CDK4 inhibitor p16-INK4, TP16, INK4, CDKN2A/ARF Intron 2 lncRNA, MLM, CDK4I, multiple tumor suppressor 1, MTS-1, INK4a, p16INK4a, multiple tumour suppressor 1, cyclin-dependent kinase 4 inhibitor A, cyclin-dependent kinase inhibitor p16, cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3, inhibitor of cdk4 A, p14ARF, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), CMM2, p16INK4, p19Arf, p16-INK4, P14, P16, ARF, CAI2, alternative reading frame, P19, cell cycle negative regulator beta, P16-INK4A, CDKN2
Source: HGNC:1787
Biotype: protein coding gene
H2-M3
(Mus musculus)Gene
Name: histocompatibility 2, M region locus 3
Synonyms: RT1-M3, RanoM3, R4B2, RanoM301, H-2M3, RanoM302, 4B2/3.7, Hmt
Source: MGI:95915
Biotype: protein coding gene
IDO1
(Homo sapiens)Gene
Name: indoleamine 2,3-dioxygenase 1
Synonyms: INDO, indoleamine-pyrrole 2,3-dioxygenase, CD107B, IDO, indolamine 2,3 dioxygenase, indole 2,3-dioxygenase, indoleamine-pyrrole 2,3 dioxygenase, IDO-1
Source: HGNC:6059
Biotype: protein coding gene
Cd44
(Mus musculus)Gene
Name: CD44 antigen
Synonyms: lymphocyte antigen 24, AW121933, METAA, AW146109, Ly-24, AU023126, HERMES, Pgp-1, RHAMM, CD44A, expressed sequence AW121933, expressed sequence AW146109, expressed sequence AU023126, phagocyte glycoprotein 1
Source: MGI:88338
Biotype: protein coding gene
Ceacam1
(Mus musculus)Gene
Name: CEA cell adhesion molecule 1
Synonyms: C-CAM, mCEA1, MHVR1, carcinoembryonic antigen 1, Hv2, Cea7, biliary glycoprotein, hepatitis virus (MHV-4) susceptibility, Bgp, Cea1, CD66a, Cc1, Hv-2, biliary glycoprotein 1, Mhv-1, resistance to MHV (A59) replication in macrophages, mmCGM2, Cea-7, mmCGM1, BGPR, Bgp1, Ccam1, Cea-1, carcinoembryonic antigen 7
Source: MGI:1347245
Biotype: protein coding gene
Tsc2
(Mus musculus)Gene
Name: TSC complex subunit 2
Synonyms: Rc, Nafld, tuberous sclerosis 2, tuberin
Source: MGI:102548
Biotype: protein coding gene
Ctla4
(Mus musculus)Gene
Name: cytotoxic T-lymphocyte-associated protein 4
Synonyms: Cd152, Ctla-4, CD152 antigen, Ly-56, CTLA-4, cytotoxic T lymphocyte-associated protein 4, sCTLA4
Source: MGI:88556
Biotype: protein coding gene
Arg2
(Mus musculus)Gene
Name: arginase type II
Synonyms: AII, AU022422, expressed sequence AU022422
Source: MGI:1330806
Biotype: protein coding gene
HLA-E
(Homo sapiens)Gene
Name: major histocompatibility complex, class I, E
Synonyms: QA1, MHC HLA-E alpha-2.1, MHC class I antigen E, HLA class I histocompatibility antigen, E alpha chain, MHC, nonclassical MHC class I antigen, HLA-6.2, MHC HLA-E alpha-1, MHC class Ib antigen, EA1.2, EA2.1, non-classical MHC class I antigen, HLA class I histocompatibility antigen, alpha chain E, lymphocyte antigen, DKFZp686P19218
Source: HGNC:4962
Biotype: protein coding gene
Scrib
(Mus musculus)Gene
Name: scribbled planar cell polarity
Synonyms: Scrb1, Crc, circletail, mKIAA0147, expressed sequence AI118201, RGD1565055, AI118201
Source: MGI:2145950
Biotype: protein coding gene
Ihh
(Mus musculus)Gene
Name: Indian hedgehog
Synonyms: Not Available
Source: MGI:96533
Biotype: protein coding gene
Scrib
(Rattus norvegicus)Gene
Name: scribble planar cell polarity protein
Synonyms: protein scribble homolog, scribbled homolog, LOC362939, LOC362938, similar to PDZ-domain protein scribble, RGD1565055, scribbled planar cell polarity protein, scribbled homolog (Drosophila)
Source: RGD:1565055
Biotype: protein coding gene
CEBPB
(Homo sapiens)Gene
Name: CCAAT enhancer binding protein beta
Synonyms: TCF-5, nuclear factor NF-IL6, CCAAT/enhancer binding protein beta, IL6DBP, liver-enriched transcriptional activator protein, CRP2, MGC32080, interleukin 6-dependent DNA-binding protein, liver-enriched inhibitory protein, c/EBP beta, nuclear factor of interleukin 6, LIP, liver activator protein, NF-IL6, C/EBP-beta, TCF5, CCAAT/enhancer-binding protein beta, LAP, transcription factor C/EBP beta, CCAAT/enhancer binding protein (C/EBP), beta, transcription factor 5
Source: HGNC:1834
Biotype: protein coding gene
Cdkn2a
(Mus musculus)Gene
Name: cyclin dependent kinase inhibitor 2A
Synonyms: INK4a-ARF, MTS1, plasmacytoma resistance 1, p19, p16Cdkn2a, Ink4a/Arf, p19ARF, ARF-INK4a, Arf, p16, Pctr1, INK4A, p16INK4a
Source: MGI:104738
Biotype: protein coding gene
Arg1
(Mus musculus)Gene
Name: arginase, liver
Synonyms: PGIF, Arg-1, expressed sequence AI256583, AI, AI256583
Source: MGI:88070
Biotype: protein coding gene
TGFB1
(Homo sapiens)Gene
Name: transforming growth factor beta 1
Synonyms: prepro-transforming growth factor beta-1, CED, TGFB, TGF-beta 1 protein, TGF-beta-1, latency-associated peptide, IBDIMDE, DPD1, transforming growth factor beta1, LAP, transforming growth factor beta-1, transforming growth factor beta-1 proprotein, TGF-beta1, TGFbeta
Source: HGNC:11766
Biotype: protein coding gene
CD24
(Homo sapiens)Gene
Name: CD24 molecule
Synonyms: CD24 antigen (small cell lung carcinoma cluster 4 antigen), CD24A, MGC75043, cd24 antigen, signal transducer CD24, FLJ43543, small cell lung carcinoma cluster 4 antigen, FLJ22950
Source: HGNC:1645
Biotype: protein coding gene
FOXJ1
(Homo sapiens)Gene
Name: forkhead box J1
Synonyms: CILD43, forkhead-like 13, forkhead box protein J1, HFH-4, MGC35202, fork head homologue 4, forkhead-related protein FKHL13, HFH4, FKHL13, forkhead transcription factor HFH-4, hepatocyte nuclear factor 3 forkhead homolog 4
Source: HGNC:3816
Biotype: protein coding gene
Cd274
(Mus musculus)Gene
Name: CD274 antigen
Synonyms: programmed cell death 1 ligand 1, PD-L1, RGD1566211, B7-H1, Pdcd1lg1
Source: MGI:1926446
Biotype: protein coding gene
Gpnmb
(Mus musculus)Gene
Name: glycoprotein (transmembrane) nmb
Synonyms: Dchil, Osteoactivin, DC-HIL, iris pigment dispersion, dendritic cell associated heparan sulfate proteoglycans dependent integrin ligand, ipd
Source: MGI:1934765
Biotype: protein coding gene
Ido1
(Mus musculus)Gene
Name: indoleamine 2,3-dioxygenase 1
Synonyms: Indo, Ido, indole 2,3-dioxygenase, indole 2,4-dioxygenase, indoleamine-pyrrole 2,3 dioxygenase
Source: MGI:96416
Biotype: protein coding gene
DLG1
(Homo sapiens)Gene
Name: discs large MAGUK scaffold protein 1
Synonyms: synapse-associated protein 97, discs, large homolog 1 (Drosophila) transcript variant 6-v2, discs, large homolog 1 (Drosophila) transcript variant 6-v1, discs, large homolog 1 transcript variant 6-v1, discs, large homolog 1 transcript variant 6-v2, hdlg, DLGH1, SAP97, DKFZp761P0818, SAP-97, discs large homolog 1, scribble cell polarity complex component, dJ1061C18.1.1, discs, large homolog 1, DKFZp781B0426, disks large homolog 1, discs large homolog 1, presynaptic protein SAP97
Source: HGNC:2900
Biotype: protein coding gene
Cebpb
(Mus musculus)Gene
Name: CCAAT/enhancer binding protein beta
Synonyms: Nfil6, LIP, C/EBP BETA, Il6dbp, C/EBPbeta, NF-IL6, nuclear protein Il6, TCF5, LAP, IL-6DBP, NF-M, CRP2
Source: MGI:88373
Biotype: protein coding gene
Cd80
(Mus musculus)Gene
Name: CD80 antigen
Synonyms: lymphocyte antigen 53, B7.1, B7-1, Ly-53, Cd28l, CD28 antigen ligand, Ly53
Source: MGI:101775
Biotype: protein coding gene
Btn2a2
(Mus musculus)Gene
Name: butyrophilin, subfamily 2, member A2
Synonyms: Not Available
Source: MGI:3606486
Biotype: protein coding gene
Lilrb4a
(Mus musculus)Gene
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4A
Synonyms: ILT3, CD85K, leukocyte immunoglobulin-like receptor, subfamily B, member 4, Gp49b, GP49B2, HM18, Lilrb4, glycoprotein 49 B
Source: MGI:102701
Biotype: protein coding gene
CTLA4
(Homo sapiens)Gene
Name: cytotoxic T-lymphocyte associated protein 4
Synonyms: cytotoxic T-lymphocyte protein 4, CD, CD152, CELIAC3, cytotoxic T-lymphocyte antigen 4, CD152 isoform, cytotoxic T-lymphocyte-associated serine esterase-4, cd152 antigen, cytotoxic T lymphocyte associated antigen 4 short spliced form, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4, celiac disease 3, ALPS5, cytotoxic T-lymphocyte-associated protein 4, IDDM12, GSE, CTLA-4, GRD4, ICOS, gluten-sensitive enteropathy, cytotoxic T-lymphocyte-associated antigen 4, insulin-dependent diabetes mellitus 12
Source: HGNC:2505
Biotype: protein coding gene
SFTPD
(Homo sapiens)Gene
Name: surfactant protein D
Synonyms: SP-D, collectin 7, pulmonary surfactant apoprotein, SFTP4, surfactant, pulmonary-associated protein D, COLEC7, collectin-7, surfactant-associated protein, pulmonary 4, PSP-D, pulmonary surfactant-associated protein D, lung surfactant protein D
Source: HGNC:10803
Biotype: protein coding gene
Casp3
(Rattus norvegicus)Gene
Name: caspase 3
Synonyms: caspase 3, apoptosis related cysteine protease, SCA-1, IRP, CPP-32, Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease), CPP32-beta, SREBP cleavage activity 1, Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease), CASP-3, MGC93645, Yama, cysteine protease CPP32, cysteine protease p32-beta, Lice, CPP32beta, apopain, caspase-3
Source: RGD:2275
Biotype: protein coding gene
HLA-G
(Homo sapiens)Gene
Name: major histocompatibility complex, class I, G
Synonyms: mutant MHC class Ib antigen, MHC class Ib antigen, HLA class I molecule, MHC class I antigen G, mutant MHC class I antigen, MHC class I antigen, b2 microglobulin, HLA class I histocompatibility antigen, alpha chain G, MHC-G, HLA G antigen, HLA-G histocompatibility antigen, class I, G
Source: HGNC:4964
Biotype: protein coding gene
Cd37
(Mus musculus)Gene
Name: CD37 antigen
Synonyms: Tspan26
Source: MGI:88330
Biotype: protein coding gene
MAD1L1
(Homo sapiens)Gene
Name: mitotic arrest deficient 1 like 1
Synonyms: MAD1, mitotic-arrest deficient 1, yeast, homolog-like 1, TXBP181, MAD1 mitotic arrest deficient-like 1 (yeast), MAD1-like protein 1, mitotic arrest deficient 1-like protein 1, PIG9, tax-binding protein 181, mitotic spindle assembly checkpoint protein MAD1, hMAD1, mitotic checkpoint MAD1 protein homolog, MAD1 mitotic arrest deficient-like 1, HsMAD1, tumor protein p53 inducible protein 9, MAD1 mitotic arrest deficient like 1, MVA7, TP53I9
Source: HGNC:6762
Biotype: protein coding gene
Prnp
(Mus musculus)Gene
Name: prion protein
Synonyms: prion protein, structural locus, CD230, expressed sequence AA960666, PrPSc, expressed sequence AI325101, prion protein, scrapie incubation time regulation, Sinc, Prn, PrP, PrPC, Prn-p, Prn-i, scrapie incubation period, AA960666, AI325101
Source: MGI:97769
Biotype: protein coding gene
Ptpn6
(Mus musculus)Gene
Name: protein tyrosine phosphatase, non-receptor type 6
Synonyms: Hcph, Ptp1C, hcp, Spin, hemopoietic cell phosphatase, motheaten, Ptph6, me, SHP-1, Shp-1
Source: MGI:96055
Biotype: protein coding gene
Vsir
(Mus musculus)Gene
Name: V-set immunoregulatory receptor
Synonyms: Dies1, VISTA, RIKEN cDNA 4632428N05 gene, PD-1H, 4632428N05Rik
Source: MGI:1921298
Biotype: protein coding gene
H2-T23
(Mus musculus)Gene
Name: histocompatibility 2, T region locus 23
Synonyms: Qa1, H-2T23, T23d, T23b, T18c(37), RTBM1, T18c, Qed-1, Qa-1, RT1-BM1, RT-BM1, 37b, 37c
Source: MGI:95957
Biotype: protein coding gene