Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: negative regulation of secretion by cell
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
BRAF
(Homo sapiens)Gene
Name: B-Raf proto-oncogene, serine/threonine kinase
Synonyms: serine/threonine-protein kinase B-raf, RAFB1, B-Raf serine/threonine-protein, B-RAF1, v-raf murine sarcoma viral oncogene homolog B1, v-raf murine sarcoma viral oncogene homolog B, p94, B-Raf proto-oncogene serine/threonine-protein kinase (p94), proto-oncogene B-Raf, MGC138284, MGC126806, NS7, B-raf, BRAF1, FLJ95109, 94 kDa B-raf protein, BRAF-1, murine sarcoma viral (v-raf) oncogene homolog B1
Source: HGNC:1097
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, MGC1571, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2
Source: HGNC:613
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
Braf
(Mus musculus)Gene
Name: Braf transforming gene
Synonyms: expressed sequence C87398, expressed sequence AA120551, expressed sequence AA387315, Braf-2, Braf2, AA387315, DNA segment, Chr 6, ERATO Doi 631, expressed, RIKEN cDNA 9930012E13 gene, C87398, AA120551, Braf transforming gene 2, D6Ertd631e, expressed sequence AA473386, AA473386, 9930012E13Rik
Source: MGI:88190
Biotype: protein coding gene
C9orf72
(Homo sapiens)Gene
Name: C9orf72-SMCR8 complex subunit
Synonyms: chromosome 9 open reading frame 72, FTDALS, DENNL72, MGC23980, hypothetical protein LOC203228, FTDALS1, uncharacterized protein C9orf72, guanine nucleotide exchange C9orf72, DENND9, RP11-27J8.2, ALSFTD, guanine nucleotide exchange factor C9orf72
Source: HGNC:28337
Biotype: protein coding gene
Pou5f1
(Mus musculus)Gene
Name: POU domain, class 5, transcription factor 1
Synonyms: Oct-4, Oct-3, Otf-4, Otf-3, octamer binding transcription factor 4, octamer binding transcription factor 3, Oct3/4, Oct4, Otf4, Otf3, Oct-3/4, Otf3-rs7, Otf3g, octamer binding transcription factor 3 related sequence 7
Source: MGI:101893
Biotype: protein coding gene
INS
(Homo sapiens)Gene
Name: insulin
Synonyms: IRDN, proinsulin, preproinsulin, insulin-dependent diabetes mellitus 2, PNDM4, IDDM, ILPR, insulin isoform U3B, MODY10, IDDM1, IDDM2
Source: HGNC:6081
Biotype: protein coding gene
Prkn
(Mus musculus)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkinson disease (autosomal recessive, juvenile) 2, parkin, Park2, Parkin, Park
Source: MGI:1355296
Biotype: protein coding gene
ACSL4
(Homo sapiens)Gene
Name: acyl-CoA synthetase long chain family member 4
Synonyms: LACS4, lignoceroyl-CoA synthase, FACL4, mental retardation, X-linked 63, long-chain fatty-acid-Coenzyme A ligase 4, acyl-CoA synthetase long-chain family member 4, MRX63, mental retardation, X-linked 68, long-chain acyl-CoA synthetase 4, MRX68, XLID63, arachidonate--CoA ligase, LACS 4, fatty-acid-Coenzyme A ligase, long-chain 4, ACS4, long-chain-fatty-acid--CoA ligase 4, acyl-CoA synthetase 4
Source: HGNC:3571
Biotype: protein coding gene
LEP
(Homo sapiens)Gene
Name: leptin
Synonyms: OBS, obesity factor, OB, leptin (obesity homolog, mouse), obese protein, obese, mouse, homolog of, FLJ94114, leptin (murine obesity homolog), LEPD
Source: HGNC:6553
Biotype: protein coding gene
NF1
(Homo sapiens)Gene
Name: neurofibromin 1
Synonyms: truncated neurofibromin 1, neurofibromin, WSS, DKFZp686J1293, FLJ21220, neurofibromatosis-related protein NF-1, neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease), NFNS, VRNF, neurofibromatosis 1
Source: HGNC:7765
Biotype: protein coding gene
FMR1
(Homo sapiens)Gene
Name: fragile X messenger ribonucleoprotein 1
Synonyms: fragile x mental retardation syndrome 1 homolog, fragile X mental retardation protein 1, fragile X mental retardation 1, FMRP, POF, fragile site, folic acid type, rare, fra(X)(q27.3), (macroorchidism, mental retardation), premature ovarian failure 1, truncated FMRP, POF1, FMR-1, FMRP translational regulator 1, MGC87458, fragile X mental retardation 1 protein, synaptic functional regulator FMR1, FRAXA
Source: HGNC:3775
Biotype: protein coding gene
FBN1
(Homo sapiens)Gene
Name: fibrillin 1
Synonyms: ACMICD, OCTD, fibrillin-1 preproprotein, MFLS, fibrillin 15, asprosin, Weill-Marchesani syndrome, ECTOL1, fibrillin-1, SSKS, MFS1, FBN, MASS, GPHYSD2, WMS, WMS2, SGS
Source: HGNC:3603
Biotype: protein coding gene
PPARG
(Homo sapiens)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: peroxisome proliferator-activated receptor-gamma splicing, peroxisome proliferator activated receptor, gamma, GLM1, PPARgamma, NR1C3, PPAR gamma, PPAR-gamma, PPARG1, peroxisome proliferator-activated receptor gamma 1, PPARG2, peroxisome proliferator-activated receptor-gamma 5, CIMT1, PPARG5, peroxisome proliferator-activated nuclear receptor gamma variant 1, peroxisome proliferator-activated receptor gamma, nuclear receptor subfamily 1 group C member 3
Source: HGNC:9236
Biotype: protein coding gene
Lep
(Mus musculus)Gene
Name: leptin
Synonyms: ob, OB, obese
Source: MGI:104663
Biotype: protein coding gene
Fbn1
(Mus musculus)Gene
Name: fibrillin 1
Synonyms: expressed sequence AI536462, Fib-1, tight skin, AI536462, Tsk
Source: MGI:95489
Biotype: protein coding gene
Pparg
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: Nr1c3, PPARgamma2, Ppar-gamma2, PPARgamma, PPAR-gamma
Source: MGI:97747
Biotype: protein coding gene
Il1b
(Mus musculus)Gene
Name: interleukin 1 beta
Synonyms: IL-1F2, IL-1B, IL-1beta, Il-1b
Source: MGI:96543
Biotype: protein coding gene
IL1B
(Homo sapiens)Gene
Name: interleukin 1 beta
Synonyms: preinterleukin 1 beta, IL1F2, interleukin-1 beta, catabolin, IL-1, IL1-BETA, IL1beta, IL-1 beta, interleukin 1beta, interleukin 1, beta, pro-interleukin-1-beta
Source: HGNC:5992
Biotype: protein coding gene
NOTCH1
(Homo sapiens)Gene
Name: notch receptor 1
Synonyms: notch 1, translocation-associated notch protein TAN-1, TAN1, neurogenic locus notch homolog protein 1, notch gene homolog 1, (drosophila), hN1, Notch homolog 1, translocation-associated, AOVD1, AOS5
Source: HGNC:7881
Biotype: protein coding gene
Tp53
(Rattus norvegicus)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor protein p53 (Li-Fraumeni syndrome), Trp53, tumor suppressor p53, transformation related protein 53, MGC112612, p53
Source: RGD:3889
Biotype: protein coding gene
Sirt1
(Mus musculus)Gene
Name: sirtuin 1
Synonyms: Sir2, expressed sequence AA673258, AA673258, Sir2alpha
Source: MGI:2135607
Biotype: protein coding gene
Il6
(Mus musculus)Gene
Name: interleukin 6
Synonyms: ILg6, Ifnb2, Il-6
Source: MGI:96559
Biotype: protein coding gene
GNAO1
(Homo sapiens)Gene
Name: G protein subunit alpha o1
Synonyms: heterotrimeric guanine nucleotide-binding protein 1G, DKFZp686O0962, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, G-ALPHA-o, EIEE17, guanine nucleotide-binding protein G(o) subunit alpha, guanine nucleotide binding protein, alpha activating polypeptide O, HG1G, GNAO, DEE17, NEDIM, GO2-q chimeric G-protein, HLA-DQB1, guanine nucleotide-binding regulatory protein 2
Source: HGNC:4389
Biotype: protein coding gene
Snca
(Mus musculus)Gene
Name: synuclein, alpha
Synonyms: alpha-Syn, alphaSYN, alpha-synuclein
Source: MGI:1277151
Biotype: protein coding gene
Drd2
(Mus musculus)Gene
Name: dopamine receptor D2
Synonyms: D2R, Drd-2, D2 receptor
Source: MGI:94924
Biotype: protein coding gene
Bcr
(Mus musculus)Gene
Name: BCR activator of RhoGEF and GTPase
Synonyms: 5133400C09Rik, RIKEN cDNA 5133400C09 gene, AI853148, expressed sequence AI853148, mKIAA3017, expressed sequence AI561783, breakpoint cluster region, AI561783
Source: MGI:88141
Biotype: protein coding gene
InR
(Drosophila melanogaster)Gene
Name: Insulin-like receptor
Synonyms: insulin-like receptor tyrosine kinase, Insulin-like Receptor, l(3)93Dj, dINSR, dIR, dInsR, dir, Igf-1 receptor, lnR, Insulin Receptor, er10, Inr-beta, dinr, DInr, IR, Insulin, insulin receptor homologue, DIRbeta, insulin receptor homolog, lethal(3)93Dj, Inr-alpha, dinR, dINR, dInr, RTK, DInR, INR, Inr, inR, insulin-like receptor, Drosophila Insulin Receptor, INS, Igfr1, insulin/IGF receptor, Insulin-receptor, DIRH, Insulin receptor, insulin/insulin-like growth factor receptor, l(3)05545, Drosophila insulin receptor, 18402, sprout, InsR, dInR, DILR, DIR, inr, Dir-b, l(3)er10, Dir-a, DIHR, dIRH, insulin receptor, insulin-receptor, CG18402
Source: FB:FBgn0283499
Biotype: protein coding gene
Ppp3ca
(Mus musculus)Gene
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Synonyms: AW413465, RIKEN cDNA 2900074D19 gene, AI841391, CN, calcineurin, Calna1, expressed sequence AW413465, 2900074D19Rik, CnA, expressed sequence AI841391, calcineurin, alpha subunit, Calna, PP2BA alpha, PP2B alpha 1, Caln
Source: MGI:107164
Biotype: protein coding gene
Nrg1
(Mus musculus)Gene
Name: neuregulin 1
Synonyms: RIKEN cDNA D230005F13 gene, HRGalpha, GGF, HGL, Hgl, GGFII, NDF, 6030402G23Rik, heregulin, ARIA, SMDF, RIKEN cDNA 6030402G23 gene, D230005F13Rik, HRG
Source: MGI:96083
Biotype: protein coding gene
Fmr1
(Mus musculus)Gene
Name: fragile X messenger ribonucleoprotein 1
Synonyms: Fmr-1, fragile X mental retardation 1, FMRP, fragile X mental retardation syndrome 1
Source: MGI:95564
Biotype: protein coding gene
Ppp1r9a
(Mus musculus)Gene
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: Neb1, 4930518N04Rik, RIKEN cDNA 2810430P21 gene, expressed sequence BB181831, p180, neurabin-I, Neurabin I, mKIAA1222, A230094E16Rik, PP1bp175, RIKEN cDNA A230094E16 gene, RIKEN cDNA 4930518N04 gene, 2810430P21Rik, BB181831, NRB
Source: MGI:2442401
Biotype: protein coding gene
Kcnj11
(Mus musculus)Gene
Name: potassium inwardly rectifying channel, subfamily J, member 11
Synonyms: Kir6.2, expressed sequence AI842722, expressed sequence AW491124, AW491124, AI842722
Source: MGI:107501
Biotype: protein coding gene
Prkg1
(Mus musculus)Gene
Name: protein kinase, cGMP-dependent, type I
Synonyms: protein kinase, cGMP-dependent, type I beta, Prkg1b, expressed sequence AW125416, Prkgr1b, AW125416, protein kinase, cGMP dependent, regulatory type I beta
Source: MGI:108174
Biotype: protein coding gene
Ceacam1
(Mus musculus)Gene
Name: CEA cell adhesion molecule 1
Synonyms: C-CAM, mCEA1, MHVR1, carcinoembryonic antigen 1, Hv2, Cea7, biliary glycoprotein, hepatitis virus (MHV-4) susceptibility, Bgp, Cea1, CD66a, Cc1, Hv-2, biliary glycoprotein 1, Mhv-1, resistance to MHV (A59) replication in macrophages, mmCGM2, Cea-7, mmCGM1, BGPR, Bgp1, Ccam1, Cea-1, carcinoembryonic antigen 7
Source: MGI:1347245
Biotype: protein coding gene
Ffar3
(Mus musculus)Gene
Name: free fatty acid receptor 3
Synonyms: Gm478, gene model 478, (NCBI), Gpr41, LOC233080, G protein-coupled receptor 41
Source: MGI:2685324
Biotype: protein coding gene
Hadh
(Mus musculus)Gene
Name: hydroxyacyl-Coenzyme A dehydrogenase
Synonyms: AW742602, expressed sequence AW742602, expressed sequence AA409008, hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase, hydroxylacyl-Coenzyme A dehydrogenase, AA409008, Schad, L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain, expressed sequence AU019341, Hadhsc, AU019341
Source: MGI:96009
Biotype: protein coding gene
Myo5a
(Mus musculus)Gene
Name: myosin VA
Synonyms: dilute, Dop, d, flailer, Myh12, myosin V, 9630007J19Rik, flr, nmf244, AI661011, flail, expressed sequence AI661011, RIKEN cDNA 9630007J19 gene, Myo5, AI413174, expressed sequence AI413174, Dbv, MVa, MyoVA
Source: MGI:105976
Biotype: protein coding gene
Nmb
(Mus musculus)Gene
Name: neuromedin B
Synonyms: RGD1562710, 3110023K12Rik, RIKEN cDNA 3110023K12 gene
Source: MGI:1915289
Biotype: protein coding gene
Kcnj6
(Mus musculus)Gene
Name: potassium inwardly-rectifying channel, subfamily J, member 6
Synonyms: KCNJ7, Kir3.2, weaver, GIRK2, wv
Source: MGI:104781
Biotype: protein coding gene
Nos1
(Mus musculus)Gene
Name: nitric oxide synthase 1, neuronal
Synonyms: NO, nitric oxide synthase 1 (macrophage), nNOS, RIKEN cDNA 2310005C01 gene, Nos-1, 2310005C01Rik, bNOS
Source: MGI:97360
Biotype: protein coding gene
IDUA
(Homo sapiens)Gene
Name: alpha-L-iduronidase
Synonyms: MPS1, iduronidase, alpha-L-, iduronidase alpha-L-, IDA, MPSI, mucopolysaccharidosis type I
Source: HGNC:5391
Biotype: protein coding gene
Cnr1
(Mus musculus)Gene
Name: cannabinoid receptor 1
Synonyms: SKR6R, CB1, CB-R, CB1R
Source: MGI:104615
Biotype: protein coding gene
Syt4
(Mus musculus)Gene
Name: synaptotagmin IV
Synonyms: Not Available
Source: MGI:101759
Biotype: protein coding gene
Stxbp5l
(Mus musculus)Gene
Name: syntaxin binding protein 5-like
Synonyms: RIKEN cDNA A830015P08 gene, type 2 diabetes mellitus 1, tomosyn-2, t2md1, insulin level locus 1, LLGL4, T2dm1, A830015P08Rik
Source: MGI:2443815
Biotype: protein coding gene
C5
(Rattus norvegicus)Gene
Name: complement C5
Synonyms: RGD1561905, Hc, anaphylatoxin, complement component 5, C5a
Source: RGD:2237
Biotype: protein coding gene
Notch1
(Mus musculus)Gene
Name: notch 1
Synonyms: Motch A, RIKEN cDNA 9930111A19 gene, N1, 9930111A19Rik, translocation-associated Notch, Tan1, TAN1, lin-12, NOTCH, Mis6
Source: MGI:97363
Biotype: protein coding gene
PRKN
(Homo sapiens)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: Parkinson disease (autosomal recessive, juvenile) 2, parkin, PDJ, parkinson disease protein 2, LPRS2, parkinson protein 2, E3 ubiquitin protein ligase (parkin), E3 ubiquitin ligase, AR-JP, parkin 2, PARK2, E3 ubiquitin-protein ligase parkin, parkinson juvenile disease protein 2, parkinson protein 2 E3 ubiquitin protein ligase
Source: HGNC:8607
Biotype: protein coding gene