Version: 8.0.0Date: Tue Jan 28 2025
Gene Molecular Function: cysteine-type endopeptidase activator activity involved in apoptotic process
RACK1
(Homo sapiens)Gene
Name: receptor for activated C kinase 1
Synonyms: protein homologous to chicken B complex protein, guanine nucleotide binding, H12.3, lung cancer oncogene 7, PIG21, receptor of activated protein C kinase 1, proliferation-inducing gene 21, guanine nucleotide binding protein beta polypeptide 2-like 1, Gnb2-rs1, guanine nucleotide-binding protein subunit beta-like protein 12.3, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, GNB2L1, HLC-7, small ribosomal subunit protein RACK1, receptor of activated protein kinase C 1, cell proliferation-inducing gene 21 protein, human lung cancer oncogene 7 protein, guanine nucleotide-binding protein subunit beta-2-like 1
Source: HGNC:4399
Biotype: protein coding gene
CASP8
(Homo sapiens)Gene
Name: caspase 8
Synonyms: ALPS2B, caspase-8, apoptotic cysteine protease, caspase 8, apoptosis-related cysteine peptidase, MCH5, caspase 8, apoptosis-related cysteine protease, Casp-8, MORT1-associated ced-3 homolog, FADD-homologous ICE/CED-3-like protease, MGC78473, FADD-like ICE, MACH-beta-1/2/3/4 protein, MACH-alpha-1/2/3 protein, FLJ17672, MACH, apoptotic protease Mch-5, FLICE, ICE-like apoptotic protease 5, CAP4
Source: HGNC:1509
Biotype: protein coding gene
Ctsh
(Mus musculus)Gene
Name: cathepsin H
Synonyms: Cat H, expressed sequence AL022844, AL022844
Source: MGI:107285
Biotype: protein coding gene
NLRP1
(Homo sapiens)Gene
Name: NLR family pyrin domain containing 1
Synonyms: VAMAS1, caspase recruitment domain-containing protein 7, NACHT, LRR and PYD domains-containing protein 1, systemic lupus erythematosus, vitiligo-related 1, SLEV1, AIADK, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1, DEFCAP, PP1044, DEFCAP-L/S, JRRP, NACHT, leucine rich repeat and PYD (pyrin domain) containing 1, CARD7, DKFZp586O1822, death effector filament-forming Ced-4-like apoptosis protein, NLR family, pyrin domain containing 1, NACHT, LRR and PYD containing protein 1, CIDED, nucleotide-binding domain and caspase recruitment domain, NAC, caspase recruitment domain protein 7, NALP1, NACHT, leucine rich repeat and PYD containing 1, MSPC, CLR17.1, KIAA0926
Source: HGNC:14374
Biotype: protein coding gene
NGF
(Homo sapiens)Gene
Name: nerve growth factor
Synonyms: HSAN5, MGC161428, Beta-NGF, nerve growth factor, beta polypeptide, NGFB, MGC161426, beta-nerve growth factor, pro-nerve growth factor long, nerve growth factor (beta polypeptide), nerve growth factor, beta subunit
Source: HGNC:7808
Biotype: protein coding gene
CTSL
(Homo sapiens)Gene
Name: cathepsin L
Synonyms: CTSL1, procathepsin L, MEP, CATL, FLJ31037, cathepsin L1, major excreted protein
Source: HGNC:2537
Biotype: protein coding gene
CASP1
(Homo sapiens)Gene
Name: caspase 1
Synonyms: caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase), interleukin 1-beta convertase, interleukin-1 beta convertase, IL1BC, ICE, interleukin 1-B converting enzyme, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), caspase-1 isoform alpha, P45, CASP-1, interleukin 1, beta, convertase, IL-1 beta-converting enzyme, IL-1BC, caspase-1, caspase 1, apoptosis-related cysteine peptidase, IL1B-convertase, CASP1 nirs variant 1, interleukin-1 beta-converting enzyme
Source: HGNC:1499
Biotype: protein coding gene
ATP2A3
(Homo sapiens)Gene
Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
Synonyms: SR Ca(2+)-ATPase 3, SERCA3, calcium pump 3, sarcoplasmic/endoplasmic reticulum calcium ATPase 3, ATPase, Ca++ transporting, ubiquitous, sarco/endoplasmic reticulum Ca2+ -ATPase, adenosine triphosphatase, calcium, sarco/endoplasmic reticulum Ca2+ ATPase, ATPase, Ca(2+)-transporting, ubiquitous, calcium-translocating P-type ATPase
Source: HGNC:813
Biotype: protein coding gene
CTSH
(Homo sapiens)Gene
Name: cathepsin H
Synonyms: cathepsin B3, CPSB, pro-cathepsin H, ACC5, ACC4, DKFZp686B24257, cathepsin BA, minichain, N-benzoylarginine-beta-naphthylamide hydrolase, ACC-5, MGC1519, ACC-4, aleurain
Source: HGNC:2535
Biotype: protein coding gene
APAF1
(Homo sapiens)Gene
Name: apoptotic peptidase activating factor 1
Synonyms: DKFZp781B1145, apoptotic protease activating factor 1, APAF-1, CED4, apoptotic protease-activating factor 1
Source: HGNC:576
Biotype: protein coding gene
NLRP12
(Homo sapiens)Gene
Name: NLR family pyrin domain containing 12
Synonyms: PYPAF7, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12, monarch-1, NALP12, NACHT, LRR and PYD containing protein 12, NACHT, LRR and PYD domains-containing protein 12, RNO, regulated by nitric oxide, NLR family, pyrin domain containing 12, RNO2, FCAS2, CLR19.3, PYRIN-containing APAF1-like protein 7, PAN6, monarch 1
Source: HGNC:22938
Biotype: protein coding gene
ScsβA
(Drosophila melanogaster)Gene
Name: Succinyl-coenzyme A synthetase beta subunit, ADP-forming
Synonyms: ATP-specific SCSbeta, Skap, SkAP, CG11963, ATP-specific form of the succinyl-CoA synthetase beta subunit, SkpA Associated Protein, skpA-associated protein, A-Sbeta, succinyl CoA synthetase, FBgn0037643, skap, CGI 1963, SkpA-associated protein, skpA associated protein
Source: FB:FBgn0037643
Biotype: protein coding gene
Ctsh
(Rattus norvegicus)Gene
Name: cathepsin H
Synonyms: cathepsin B3, cathepsin BA, pro-cathepsin H
Source: RGD:2447
Biotype: protein coding gene
BCL2L13
(Homo sapiens)Gene
Name: BCL2 like 13
Synonyms: BCL-RAMBO, Bcl2-L-13, MIL1, BCL2-like 13 (apoptosis facilitator), bcl-2-like protein 13
Source: HGNC:17164
Biotype: protein coding gene
Ngf
(Mus musculus)Gene
Name: nerve growth factor
Synonyms: Ngfb, nerve growth factor, beta, beta-NGF
Source: MGI:97321
Biotype: protein coding gene
Bad
(Mus musculus)Gene
Name: BCL2-associated agonist of cell death
Synonyms: Bbc2, Bad_v1, Bad_v2, AI325008, expressed sequence AI325008
Source: MGI:1096330
Biotype: protein coding gene
NKX3-1
(Homo sapiens)Gene
Name: NK3 homeobox 1
Synonyms: NK3 transcription factor related, locus 1, homeobox protein Nkx-3.1, NKX3A, NKX3.1, BAPX2, NK3 transcription factor homolog A, NKX3, homeobox protein NK-3 homolog A, NK homeobox, family 3, A
Source: HGNC:7838
Biotype: protein coding gene
BEX3
(Homo sapiens)Gene
Name: brain expressed X-linked 3
Synonyms: brain-expressed X-linked protein 3, HGR74, nerve growth factor receptor (TNFRSF16) associated protein 1, p75NTR-associated cell death executor, DXS6984E, ovarian granulosa cell protein (13kD), NADE, nerve growth factor receptor-associated protein 1, NGFRAP1, Bex, ovarian granulosa cell 13.0 kDa protein HGR74, brain expressed, X-linked 3, Hero20
Source: HGNC:13388
Biotype: protein coding gene
BAD
(Homo sapiens)Gene
Name: BCL2 associated agonist of cell death
Synonyms: BCL2L8, bcl2 antagonist of cell death, bcl-2-binding component 6, BCL2-associated agonist of cell death, BCL2-antagonist of cell death, bcl2-L-8, bcl-2-like protein 8, BCL-X/BCL-2 binding protein, BCL2-binding component 6, BBC2, bcl-XL/Bcl-2-associated death promoter, bcl-2 associated death agonist, BCL2-binding protein
Source: HGNC:936
Biotype: protein coding gene
CTSS
(Homo sapiens)Gene
Name: cathepsin S
Synonyms: FLJ50259, MGC3886
Source: HGNC:2545
Biotype: protein coding gene
CTSK
(Homo sapiens)Gene
Name: cathepsin K
Synonyms: cathepsin O1, cathepsin O, CTSO2, CTSO, CTSO1, CTS02, PKND, cathepsin X, MGC23107, PYCD, cathepsin O2
Source: HGNC:2536
Biotype: protein coding gene
Tnfrsf10b
(Mus musculus)Gene
Name: tumor necrosis factor receptor superfamily, member 10b
Synonyms: TRAIL-R2, TRICKB, DR5, Killer/Dr5, Ly98, KILLER, Trail Receptor, TRAILR2, TRICK2B, TRICK2A
Source: MGI:1341090
Biotype: protein coding gene
Rack1
(Mus musculus)Gene
Name: receptor for activated C kinase 1
Synonyms: guanine nucleotide binding protein, beta-2, related sequence 1, p205, Gnb2-rs1, guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1, guanine nucleotide binding protein, beta 2, related sequence 1, GB-like, Gnb2l1
Source: MGI:101849
Biotype: protein coding gene
Casp8
(Mus musculus)Gene
Name: caspase 8
Synonyms: Caspase-8, Mch5, CASP-8, MACH, FLICE
Source: MGI:1261423
Biotype: protein coding gene
RPS27L
(Homo sapiens)Gene
Name: ribosomal protein S27 like
Synonyms: 40S ribosomal protein S27-like, ribosomal protein S27-like, ribosomal protein eS27-like, small ribosomal subunit protein eS27-like
Source: HGNC:18476
Biotype: protein coding gene
CASP8AP2
(Homo sapiens)Gene
Name: caspase 8 associated protein 2
Synonyms: KIAA1315, CASP8-associated protein 2, human FLASH, FLASH homolog RIP25, RIP25, CASP8 associated protein 2, CED-4, FLICE associated huge, FLJ11208, FLICE-associated huge protein, FLASH
Source: HGNC:1510
Biotype: protein coding gene
CTSV
(Homo sapiens)Gene
Name: cathepsin V
Synonyms: MGC125957, CATL2, cathepsin L2, preproprotein, cathepsin U, CTSU, cathepsin L2, CTSL2
Source: HGNC:2538
Biotype: protein coding gene
ced-3
(Caenorhabditis elegans)Gene
Name: CEll Death abnormality 3
Synonyms: CELE_C48D1.2, C48D1.2
Source: WB:WBGene00000417
Biotype: protein coding gene
Nkx3-1
(Mus musculus)Gene
Name: NK3 homeobox 1
Synonyms: NKX3A, NKX3.1, Bax, Nkx-3.1, bagpipe, Nkx3.1
Source: MGI:97352
Biotype: protein coding gene
ctsh
(Danio rerio)Gene
Name: cathepsin H
Synonyms: wu:fc44c02, zgc:85774, fc44c02
Source: ZFIN:ZDB-GENE-030131-3539
Biotype: protein coding gene
Apaf1
(Mus musculus)Gene
Name: apoptotic peptidase activating factor 1
Synonyms: forebrain overgrowth, 6230400I06Rik, Apaf1l, apoptotic protease activating factor 1 like, RIKEN cDNA 6230400I06 gene, fog
Source: MGI:1306796
Biotype: protein coding gene
Cyt-c-d
(Drosophila melanogaster)Gene
Name: Cytochrome c distal
Synonyms: CytC1, CytC, ms(2)04445, blanks, Cyt c, bs30f07.y1, cytochrome c distal, CYC, cytochrome c-d, pDMc02, Cyt-c1, Cytochrome C, cyt-c-d, DC3, dc3, cytochrome-c-d, cyt.c, cytochrome c, CG13263, Cytc, bln, Cytc-d, Cyt C, cyt c, cyt c-d, Cytochrome c, cytc-d, cyt.c-d, CytC-1, CYTC, cytochrome C
Source: FB:FBgn0086907
Biotype: protein coding gene
Dredd
(Drosophila melanogaster)Gene
Name: Death related ced-3/Nedd2-like caspase
Synonyms: Dcp2, Dedd, DCP-2/DREDD, Dredd, dDredd, DCP-2, caspase, DREDD, EG:115C2.9, Death caspase-2, Dredd/DCP-2, death-related ced-3/neural precursor cell expressed developmentally downregulated 2 (NEDD2)-like protein, Ced-3-like/Nedd2-like protein, anon-1BCa, CASP8_DROME, dcp-2/dredd, dredd, DmDREDD, CG7486, Drosophila caspase, Dcp-2/Dredd, Redd, Death related ced-3/Nedd2-like protein, Dcp-2, DCP2
Source: FB:FBgn0020381
Biotype: protein coding gene
Mapk9
(Mus musculus)Gene
Name: mitogen-activated protein kinase 9
Synonyms: c-Jun N-terminal kinase, protein kinase, mitogen-activated 9, Prkm9, JNK/SAPK alpha, JNK2, AI851083, expressed sequence AI851083, SAPK
Source: MGI:1346862
Biotype: protein coding gene
Atp2a3
(Mus musculus)Gene
Name: ATPase, Ca++ transporting, ubiquitous
Synonyms: SERCA3, Serca3
Source: MGI:1194503
Biotype: protein coding gene
cpl-1
(Caenorhabditis elegans)Gene
Name: CathePsin L family 1
Synonyms: T03E6.7, CELE_T03E6.7
Source: WB:WBGene00000776
Biotype: protein coding gene
Atp2a3
(Rattus norvegicus)Gene
Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
Synonyms: SR Ca(2+)-ATPase 3, SERCA3, calcium pump 3, sarcoplasmic/endoplasmic reticulum calcium ATPase 3, ATPase, Ca++ transporting, ubiquitous
Source: RGD:2175
Biotype: protein coding gene
Apaf1
(Rattus norvegicus)Gene
Name: apoptotic peptidase activating factor 1
Synonyms: apoptotic protease activating factor 1, apaf-1, apoptotic protease-activating factor 1
Source: RGD:620575
Biotype: protein coding gene
Bad
(Rattus norvegicus)Gene
Name: BCL2-associated agonist of cell death
Synonyms: Bad_v1, bcl-xL/Bcl-2-associated death promoter, Bad_v2, bcl2 antagonist of cell death, Bcl2-antagonist of cell death, bcl2-associated death promoter, bcl-2-binding component 6, bcl-2 associated death agonist, BCL2-associated agonist of cell death, variant 2, BCL2-associated agonist of cell death, variant 1, MGC72439
Source: RGD:620103
Biotype: protein coding gene
Rack1
(Rattus norvegicus)Gene
Name: receptor for activated C kinase 1
Synonyms: receptor for activated protein kinase C, guanine nucleotide binding protein, beta polypeptide 2-like 1, guanine nucleotide binding protein (G protein) beta polypeptide 2-like 1, receptor of activated protein C kinase 1, protein kinase C receptor, small ribosomal subunit protein RACK1, receptor of activated protein kinase C 1, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1, receptor for activated C kinase, Gnb2l1, guanine nucleotide-binding protein subunit beta-2-like 1
Source: RGD:69229
Biotype: protein coding gene
Rps27l
(Mus musculus)Gene
Name: ribosomal protein S27-like
Synonyms: Rps27l1, 1810034D23Rik, RIKEN cDNA 1810034D23 gene
Source: MGI:1915191
Biotype: protein coding gene
PYCARD
(Homo sapiens)Gene
Name: PYD and CARD domain containing
Synonyms: caspase recruitment domain-containing protein 5, target of methylation-induced silencing 1, apoptosis-associated speck-like protein containing a CARD, PYD and CARD domain-containing protein, CARD5, TMS1, ASC, caspase recruitment domain protein 5, target of methylation-induced silencing-1, MGC10332, hASC, TMS, TMS-1
Source: HGNC:16608
Biotype: protein coding gene
Bcl10
(Mus musculus)Gene
Name: B cell leukemia/lymphoma 10
Synonyms: expressed sequence C81403, BCL-10, mE10, C81403, expressed sequence AI132454, AI132454, cE10
Source: MGI:1337994
Biotype: protein coding gene
ctsl.1
(Danio rerio)Gene
Name: cathepsin L.1
Synonyms: ctslc, zgc:92089
Source: ZFIN:ZDB-GENE-040718-61
Biotype: protein coding gene
Casp8ap2
(Mus musculus)Gene
Name: caspase 8 associated protein 2
Synonyms: D4Ertd659e, expressed sequence AA387232, AA387232, mKIAA1315, DNA segment, Chr 4, ERATO Doi 659, expressed, FLASH
Source: MGI:1349399
Biotype: protein coding gene
Casp8ap2
(Rattus norvegicus)Gene
Name: caspase 8 associated protein 2
Synonyms: LOC313128, CASP8-associated protein 2
Source: RGD:1305771
Biotype: protein coding gene
Nkx3-1
(Rattus norvegicus)Gene
Name: NK3 homeobox 1
Synonyms: NK-3 transcription factor, locus 1 (Drosophila), LOC305999, MGC124859, homeobox protein Nkx-3.1, NK-3 transcription factor, locus 1, Nkx3.1
Source: RGD:1305369
Biotype: protein coding gene
ced-4
(Caenorhabditis elegans)Gene
Name: CEll Death abnormality 4
Synonyms: CELE_C35D10.9, C35D10.9
Source: WB:WBGene00000418
Biotype: protein coding gene
Rps27l
(Rattus norvegicus)Gene
Name: ribosomal protein S27-like
Synonyms: 40S ribosomal protein S27-like, Rps27l1, small ribosomal subunit protein eS27-like, LOC681429, ribosomal protein S27, similar to 40S ribosomal protein S27-like protein, ribosomal protein S27-like 1
Source: RGD:1595396
Biotype: protein coding gene
Casp8
(Rattus norvegicus)Gene
Name: caspase 8
Synonyms: caspase-8, CASP-8
Source: RGD:620945
Biotype: protein coding gene