Version: 8.0.0Date: Tue Jan 28 2025
Gene Molecular Function: eukaryotic translation initiation factor 2alpha kinase activity
ATM
(Homo sapiens)Gene
Name: ATM serine/threonine kinase
Synonyms: serine/threonine kinase ATM, TEL1, telomere maintenance 1, homolog, MGC74674, human phosphatidylinositol 3-kinase homolog, ATDC, truncated ATM serine/threonine kinase, DKFZp781A0353, ATA, AT mutated, ATC, ataxia telangiectasia mutated, ATD, TEL1, ataxia telangiectasia mutated (includes complementation groups A, C and D), ATE, A-T mutated, serine-protein kinase ATM, TELO1, AT1
Source: HGNC:795
Biotype: protein coding gene
BRAF
(Homo sapiens)Gene
Name: B-Raf proto-oncogene, serine/threonine kinase
Synonyms: serine/threonine-protein kinase B-raf, RAFB1, B-Raf serine/threonine-protein, B-RAF1, v-raf murine sarcoma viral oncogene homolog B1, v-raf murine sarcoma viral oncogene homolog B, p94, B-Raf proto-oncogene serine/threonine-protein kinase (p94), proto-oncogene B-Raf, MGC138284, MGC126806, NS7, B-raf, BRAF1, FLJ95109, 94 kDa B-raf protein, BRAF-1, murine sarcoma viral (v-raf) oncogene homolog B1
Source: HGNC:1097
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: mechanistic target of rapamycin, rapamycin target protein 1, rapamycin and FKBP12 target 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FKBP12-rapamycin complex-associated protein 1, FRAP2, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, SKS, FRAP, serine/threonine-protein kinase mTOR, RAPT1, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
Braf
(Mus musculus)Gene
Name: Braf transforming gene
Synonyms: expressed sequence C87398, expressed sequence AA120551, expressed sequence AA387315, Braf-2, Braf2, AA387315, DNA segment, Chr 6, ERATO Doi 631, expressed, RIKEN cDNA 9930012E13 gene, C87398, AA120551, Braf transforming gene 2, D6Ertd631e, expressed sequence AA473386, AA473386, 9930012E13Rik
Source: MGI:88190
Biotype: protein coding gene
CHEK2
(Homo sapiens)Gene
Name: checkpoint kinase 2
Synonyms: CDS1, HuCds1, PP1425, serine/threonine-protein kinase Chk2, checkpoint-like protein CHK2, TPDS4, CHK2 checkpoint homolog, cds1 homolog, RAD53, truncated checkpoint kinase 2, CHK2, LFS2, hCds1
Source: HGNC:16627
Biotype: protein coding gene
TSSK2
(Homo sapiens)Gene
Name: testis specific serine kinase 2
Synonyms: TSK2, SPOGA2, serine/threonine kinase 22B (spermiogenesis associated), testis-specific serine/threonine-protein kinase 2, testis-specific kinase 2, testicular secretory protein Li 61, serine/threonine-protein kinase 22B, testis-specific serine kinase 2, spermiogenesis associated 2, TSSK-2, testis specific serine threonine kinase 2, FLJ38613, DGS-G, diGeorge syndrome protein G, TSK-2, STK22B
Source: HGNC:11401
Biotype: protein coding gene
SNF1
(Saccharomyces cerevisiae)Gene
Name: Sucrose NonFermenting
Synonyms: CCR1, PAS14, CAT1, GLC2, HAF3, YDR477W
Source: SGD:S000002885
Biotype: protein coding gene
ATR
(Homo sapiens)Gene
Name: ATR serine/threonine kinase
Synonyms: FRAP-related protein 1, MEC1, ataxia telangiectasia and Rad3-related protein, MEC1, mitosis entry checkpoint 1, homolog, ataxia telangiectasia and Rad3 related, FRAP-related protein-1, FRP1, SCKL1, serine/threonine-protein kinase ATR, protein kinase ATR, SCKL, Rad3 related protein, FCTCS
Source: HGNC:882
Biotype: protein coding gene
AKT1
(Homo sapiens)Gene
Name: AKT serine/threonine kinase 1
Synonyms: serine-threonine protein kinase, PRKBA, protein kinase B alpha, v-akt murine thymoma viral oncogene homolog 1, PKB, CWS6, MGC99656, AKT, PKB-ALPHA, RAC-alpha serine/threonine-protein kinase, AKT1m, RAC, proto-oncogene c-Akt, rac protein kinase alpha, RAC-PK-alpha, RAC-ALPHA, protein kinase B, PKB alpha, v-akt murine thymoma viral oncogene-like protein 1
Source: HGNC:391
Biotype: protein coding gene
STK11
(Homo sapiens)Gene
Name: serine/threonine kinase 11
Synonyms: serine/threonine-protein kinase STK11, polarization-related protein LKB1, renal carcinoma antigen NY-REN-19, serine/threonine kinase 11 (peutz-jeghers syndrome), liver kinase B1, serine/threonine-protein kinase 11, PJS, serine/threonine-protein kinase LKB1, hLKB1, LKB1
Source: HGNC:11389
Biotype: protein coding gene
Ulk4
(Mus musculus)Gene
Name: unc-51-like kinase 4
Synonyms: RIKEN cDNA 4932415A06 gene, 4932415A06Rik, RGD1565726
Source: MGI:1921622
Biotype: protein coding gene
CSNK2A1
(Homo sapiens)Gene
Name: casein kinase 2 alpha 1
Synonyms: CK II alpha 3, protein kinase CK2, CSNK2A3, CK2A1, casein kinase 2, alpha 1 polypeptide, casein kinase II subunit alpha, casein kinase II alpha 1 subunit, OCNDS, casein kinase ii, alpha 1 polypeptide, CKII, CK II alpha, Cka1, Cka2, CK2 catalytic subunit alpha, casein kinase II alpha 1 polypeptide pseudogene
Source: HGNC:2457
Biotype: protein coding gene
Cit
(Rattus norvegicus)Gene
Name: citron rho-interacting serine/threonine kinase
Synonyms: LOC288698, postsynaptic density protein (citron), citron kinase, citron Rho-interacting kinase, citron (rho-interacting, serine/threonine kinase 21), rho-interacting, serine/threonine-protein kinase 21, citron-K, CRIK, citron, citron-K kinase
Source: RGD:70878
Biotype: protein coding gene
ATG1
(Saccharomyces cerevisiae)Gene
Name: AuTophaGy related
Synonyms: YGL180W, APG1, CVT10, AUT3
Source: SGD:S000003148
Biotype: protein coding gene
Akt1
(Mus musculus)Gene
Name: thymoma viral proto-oncogene 1
Synonyms: PKB/Akt, PKB, Akt, PKBalpha
Source: MGI:87986
Biotype: protein coding gene
LRRK2
(Homo sapiens)Gene
Name: leucine rich repeat kinase 2
Synonyms: RIPK7, leucine-rich repeat kinase 2, leucine-rich repeat serine/threonine-protein kinase 2, ROCO2, augmented in rheumatoid arthritis 17, AURA17, PARK8, DARDARIN, Parkinson disease (autosomal dominant) 8
Source: HGNC:18618
Biotype: protein coding gene
TEL1
(Saccharomyces cerevisiae)Gene
Name: TELomere maintenance
Synonyms: YBL088C
Source: SGD:S000000184
Biotype: protein coding gene
CDC15
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: RLT1, LYT1, YAR019C
Source: SGD:S000000072
Biotype: protein coding gene
Bcr
(Mus musculus)Gene
Name: BCR activator of RhoGEF and GTPase
Synonyms: 5133400C09Rik, RIKEN cDNA 5133400C09 gene, AI853148, expressed sequence AI853148, mKIAA3017, expressed sequence AI561783, breakpoint cluster region, AI561783
Source: MGI:88141
Biotype: protein coding gene
Gsk3b
(Mus musculus)Gene
Name: glycogen synthase kinase 3 beta
Synonyms: expressed sequence C86142, GSK-3beta, GSK3, RIKEN cDNA 8430431H08 gene, RIKEN cDNA 7330414F15 gene, GSK-3, 7330414F15Rik, C86142, 8430431H08Rik
Source: MGI:1861437
Biotype: protein coding gene
HUNK
(Homo sapiens)Gene
Name: hormonally up-regulated Neu-associated kinase
Synonyms: serine/threonine-protein kinase MAK-V, hormonally up-regulated neu tumor-associated kinase, hormonally upregulated Neu-associated kinase, hormonally upregulated neu tumor-associated kinase, serine/threonine protein kinase MAK-V, B19
Source: HGNC:13326
Biotype: protein coding gene
ULK1
(Homo sapiens)Gene
Name: unc-51 like autophagy activating kinase 1
Synonyms: FLJ38455, serine/threonine-protein kinase ULK1, ATG1 autophagy related 1 homolog, ATG1, UNC51, FLJ46475, autophagy-related protein 1 homolog, Unc51.1, hATG1, ATG1A
Source: HGNC:12558
Biotype: protein coding gene
SCH9
(Saccharomyces cerevisiae)Gene
Name: Not Available
Synonyms: YHR205W, KOM1, HRM2
Source: SGD:S000001248
Biotype: protein coding gene
Raf1
(Mus musculus)Gene
Name: v-raf-leukemia viral oncogene 1
Synonyms: 6430402F14Rik, c-Raf, expressed sequence AA990557, Raf-1, Craf1 transforming gene, sarcoma 3611 oncogene, v-Raf, expressed sequence BB129353, AA990557, BB129353, Craf1, murine sarcoma 3611 oncogene 1, RIKEN cDNA 6430402F14 gene
Source: MGI:97847
Biotype: protein coding gene
CSNK2A2
(Homo sapiens)Gene
Name: casein kinase 2 alpha 2
Synonyms: FLJ43934, casein kinase II subunit alpha', CSNK2A1, CK2alpha', CK2A2, casein kinase 2 alpha', CK II alpha', casein kinase 2, alpha prime polypeptide
Source: HGNC:2459
Biotype: protein coding gene
PAK1
(Homo sapiens)Gene
Name: p21 (RAC1) activated kinase 1
Synonyms: alpha-PAK, MGC130001, STE20 homolog, yeast, p21-activated kinase 1, MGC130000, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), IDDMSSD, p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related), serine/threonine-protein kinase PAK 1, PAK-1, p65-PAK, PAKalpha, p21 protein (Cdc42/Rac)-activated kinase 1
Source: HGNC:8590
Biotype: protein coding gene
MARK4
(Homo sapiens)Gene
Name: microtubule affinity regulating kinase 4
Synonyms: PAR-1D, Nbla00650, KIAA1860, MARKL1L, MARKL1, MAP/microtubule affinity-regulating kinase-like 1, FLJ12177, MARK4 serine/threonine protein kinase, MARK4S, MAP/microtubule affinity-regulating kinase 4, MAP/microtubule affinity-regulating kinase like 1, MARK4L, putative protein product of Nbla00650, FLJ90097
Source: HGNC:13538
Biotype: protein coding gene
Lrrk2
(Mus musculus)Gene
Name: leucine-rich repeat kinase 2
Synonyms: cDNA sequence, clone 3-75, Gm927, RIKEN cDNA 4921513O20 gene, AW561911, RIKEN cDNA D630001M17 gene, RIKEN cDNA 9330188B09 gene, 4921513O20Rik, D630001M17Rik, LOC381026, gene model 927, (NCBI), cI-46, 9330188B09Rik
Source: MGI:1913975
Biotype: protein coding gene
Mtor
(Mus musculus)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: expressed sequence AI327068, AI327068, flat-top, RAFT1, 2610315D21Rik, flat, FKBP-rapamycin-associated protein FRAP, Frap1, mechanistic target of rapamycin (serine/threonine kinase), RAPT1, FK506 binding protein 12-rapamycin associated protein 1, RIKEN cDNA 2610315D21 gene
Source: MGI:1928394
Biotype: protein coding gene
TOR1
(Saccharomyces cerevisiae)Gene
Name: Target Of Rapamycin
Synonyms: YJR066W, DRR1
Source: SGD:S000003827
Biotype: protein coding gene
FRK1
(Saccharomyces cerevisiae)Gene
Name: Fatty acyl-CoA synthetase and RNA processing-associated Kinase
Synonyms: YPL141C
Source: SGD:S000006062
Biotype: protein coding gene
Ern1
(Mus musculus)Gene
Name: endoplasmic reticulum to nucleus signalling 1
Synonyms: C85377, Ire1p, inositol-requiring 1 alpha (yeast), RIKEN cDNA 9030414B18 gene, Ire1a, AI225830, expressed sequence AI225830, expressed sequence C85377, RGD1559716, 9030414B18Rik, Ire1alpha
Source: MGI:1930134
Biotype: protein coding gene
Nek8
(Mus musculus)Gene
Name: NIMA (never in mitosis gene a)-related expressed kinase 8
Synonyms: juvenile cystic kidney, RIKEN cDNA 4632401F23 gene, jck, Mutant line 1449, 4632401F23Rik, b2b1449Clo
Source: MGI:1890646
Biotype: protein coding gene
Prkdc
(Mus musculus)Gene
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNAPDcs, DNA-PKcs, doxorubicin nephropathy, XRCC7, DNA-PK, expressed sequence AI326420, AU019811, dxnph, severe combined immunodeficiency, DOXNPH, expressed sequence AU019811, slip, AI326420, scid
Source: MGI:104779
Biotype: protein coding gene
Aak1
(Mus musculus)Gene
Name: AP2 associated kinase 1
Synonyms: DNA segment, Chr 6, ERATO Doi 245, expressed, cDNA sequence BC028270, BC028270, AU067724, AU067726, R75501, expressed sequence C79663, 5530400K14Rik, MGC:40785, D6Ertd245e, expressed sequence R75501, RIKEN cDNA 5530400K14 gene, mKIAA1048, C79663, RGD1563580, expressed sequence AU067726, expressed sequence AU067724
Source: MGI:1098687
Biotype: protein coding gene
Rock1
(Mus musculus)Gene
Name: Rho-associated coiled-coil containing protein kinase 1
Synonyms: P160Rock, RIKEN cDNA 1110055K06 gene, 1110055K06Rik, ROCK-I, Rock-I
Source: MGI:107927
Biotype: protein coding gene
PRKDC
(Homo sapiens)Gene
Name: protein kinase, DNA-activated, catalytic subunit
Synonyms: HYRC, DNA-PKcs, DNAPKc, XRCC7, DNA-PK catalytic subunit, DNA-dependent protein kinase catalytic subunit, IMD26, p460, p350, DNPK1, HYRC1, DNAPK, DNA-PKC, hyper-radiosensitivity of murine scid mutation, complementing 1
Source: HGNC:9413
Biotype: protein coding gene
Taok2
(Mus musculus)Gene
Name: TAO kinase 2
Synonyms: MAP3K17, Tao2, TAO2, TAO1, mKIAA0881, PSK1, 1110033K02Rik, RIKEN cDNA 1110033K02 gene
Source: MGI:1915919
Biotype: protein coding gene
IRE1
(Saccharomyces cerevisiae)Gene
Name: Inositol REquiring
Synonyms: ERN1, YHR079C
Source: SGD:S000001121
Biotype: protein coding gene
Stk32b
(Mus musculus)Gene
Name: serine/threonine kinase 32B
Synonyms: STKG6, 2510009F08Rik, RIKEN cDNA 2510009F08 gene, serine threonine kinase 32, YANK2, Stk32
Source: MGI:1927552
Biotype: protein coding gene
Tnik
(Mus musculus)Gene
Name: TRAF2 and NCK interacting kinase
Synonyms: C530008O15Rik, RIKEN cDNA 1500031A17 gene, RGD1561817, 4831440I19Rik, expressed sequence AI451411, RIKEN cDNA C630040K21 gene, RIKEN cDNA 4831440I19 gene, 1500031A17Rik, AI451411, C630040K21Rik, RIKEN cDNA C530008O15 gene
Source: MGI:1916264
Biotype: protein coding gene
Myo3a
(Mus musculus)Gene
Name: myosin IIIA
Synonyms: 9030416P08Rik, RIKEN cDNA 9030416P08 gene
Source: MGI:2183924
Biotype: protein coding gene
HRR25
(Saccharomyces cerevisiae)Gene
Name: HO and Radiation Repair
Synonyms: YPL204W, KTI14
Source: SGD:S000006125
Biotype: protein coding gene
TOR2
(Saccharomyces cerevisiae)Gene
Name: Target Of Rapamycin
Synonyms: YKL203C, DRR2
Source: SGD:S000001686
Biotype: protein coding gene
Mknk1
(Mus musculus)Gene
Name: MAP kinase-interacting serine/threonine kinase 1
Synonyms: Mnk1, RIKEN cDNA 2410048M24 gene, 2410048M24Rik
Source: MGI:894316
Biotype: protein coding gene
Cask
(Mus musculus)Gene
Name: calcium/calmodulin dependent serine protein kinase
Synonyms: DXRib1, DNA segment, Chr X, Princeton 1, LIN-2, DXPri1, mLin-2, Pals3
Source: MGI:1309489
Biotype: protein coding gene
TTN
(Homo sapiens)Gene
Name: titin
Synonyms: CMYP5, CMYO5, LGMDR10, CMPD4, CMH9, CMD1G, FLJ34413, FLJ43066, TMD, FLJ26020, MYLK5, HMERF, EOMFC, FLJ32040, FLJ39564, rhabdomyosarcoma antigen MU-RMS-40.14, LGMD2J, connectin, FLJ26409, SALMY, DKFZp451N061
Source: HGNC:12403
Biotype: protein coding gene
CSNK1A1
(Homo sapiens)Gene
Name: casein kinase 1 alpha 1
Synonyms: CKIalpha, PRO2975, HLCDGP1, HEL-S-77p, clock regulator kinase, CK1a, CK1, CKI-alpha, casein kinase I isoform alpha, down-regulated in lung cancer, epididymis secretory sperm binding protein Li 77p, casein kinase 1, alpha 1, CK1alpha, CKIa
Source: HGNC:2451
Biotype: protein coding gene
TBK1
(Homo sapiens)Gene
Name: TANK binding kinase 1
Synonyms: FLJ11330, IIAE8, NF-kB-activating kinase, TANK-binding kinase 1, NAK, FTDALS4, serine/threonine-protein kinase TBK1, AIARV, T2K, NF-kappa-B-activating kinase
Source: HGNC:11584
Biotype: protein coding gene
snrka
(Danio rerio)Gene
Name: SNF related kinase a
Synonyms: snrk, zgc:92047, wu:fc65g02
Source: ZFIN:ZDB-GENE-040718-84
Biotype: protein coding gene