Version: 8.0.0Date: Tue Jan 28 2025
Gene Molecular Function: peptidase activator activity
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, Alzheimer disease amyloid beta protein, cerebrovascular amyloid peptide, protease nexin II, expressed sequence AL024401, AL024401, RIKEN cDNA E030013M08 gene, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
Tgfb1
(Mus musculus)Gene
Name: transforming growth factor, beta 1
Synonyms: Tgfb-1, TGF-beta 1, Tgfb, TGFbeta1, TGF-beta1
Source: MGI:98725
Biotype: protein coding gene
VCP
(Homo sapiens)Gene
Name: valosin containing protein
Synonyms: epididymis secretory protein Li 70, IBMPFD, valosin-containing protein, HEL-S-70, MGC148092, CMT2Y, TERA, FTDALS6, transitional endoplasmic reticulum ATPase, yeast Cdc48p homolog, p97, 15S Mg(2+)-ATPase p97 subunit, HEL-220, MGC8560, TER ATPase, CDC48, MGC131997, ALS14, IBMPFD1, epididymis luminal protein 220
Source: HGNC:12666
Biotype: protein coding gene
NLRP3
(Homo sapiens)Gene
Name: NLR family pyrin domain containing 3
Synonyms: caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, cryopyrin, NACHT, LRR and PYD domains - containing protein 3, CIAS1, deafness, autosomal dominant 34, NACHT, LRR and PYD domains-containing protein 3, cold autoinflammatory syndrome 1, FCAS, cryopyrin, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, AII/AVP receptor-like, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3, FCAS1, AGTAVPRL, DFNA34, AII, CLR1.1, MWS, PYPAF1, AII/AVP, NACHT, LRR and PYD containing protein 3, NLR family, pyrin domain containing 3, FLJ95925, NALP3, C1orf7, angiotensin/vasopressin receptor AII/AVP-like, FCU, AVP, KEFH
Source: HGNC:16400
Biotype: protein coding gene
Cav1
(Mus musculus)Gene
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1, Cav
Source: MGI:102709
Biotype: protein coding gene
Fn1
(Mus musculus)Gene
Name: fibronectin 1
Synonyms: Fn, FIBNEC, fn-1, Fn-1
Source: MGI:95566
Biotype: protein coding gene
HSPD1
(Homo sapiens)Gene
Name: heat shock protein family D (Hsp60) member 1
Synonyms: HSP60, GROEL, short heat shock protein 60 Hsp60s1, heat shock 60kDa protein 1 (chaperonin), heat shock protein 60 (liver), mitochondrial matrix protein P1, CPN60, P60 lymphocyte protein, HuCHA60, HSP-60, 60 kDa heat shock protein, mitochondrial, HLD4, 60 kDa chaperonin, spastic paraplegia 13 (autosomal dominant), heat shock protein 65, HSP65, heat shock protein family D member 1, SPG13, chaperonin 60
Source: HGNC:5261
Biotype: protein coding gene
AIM2
(Homo sapiens)Gene
Name: absent in melanoma 2
Synonyms: LOC105371461, uncharacterized LOC105371461, interferon-inducible protein AIM2, PYHIN4
Source: HGNC:357
Biotype: protein coding gene
RACK1
(Homo sapiens)Gene
Name: receptor for activated C kinase 1
Synonyms: protein homologous to chicken B complex protein, guanine nucleotide binding, H12.3, lung cancer oncogene 7, PIG21, receptor of activated protein C kinase 1, proliferation-inducing gene 21, guanine nucleotide binding protein beta polypeptide 2-like 1, Gnb2-rs1, guanine nucleotide-binding protein subunit beta-like protein 12.3, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, GNB2L1, HLC-7, small ribosomal subunit protein RACK1, receptor of activated protein kinase C 1, cell proliferation-inducing gene 21 protein, human lung cancer oncogene 7 protein, guanine nucleotide-binding protein subunit beta-2-like 1
Source: HGNC:4399
Biotype: protein coding gene
CAV1
(Homo sapiens)Gene
Name: caveolin 1
Synonyms: caveolin 1, caveolae protein, 22kDa, BSCL3, caveolin-1, VIP21, CGL3, CAV, cell growth-inhibiting protein 32, MSTP085, PPH3, LCCNS
Source: HGNC:1527
Biotype: protein coding gene
FN1
(Homo sapiens)Gene
Name: fibronectin 1
Synonyms: CIG, MSF, migration-stimulating factor, DKFZp686O13149, DKFZp686I1370, FN, DKFZp686F10164, FNZ, GFND2, ED-B, GFND, fibronectin, FINC, SMDCF, DKFZp686H0342, lnc-ABCA12-8, LETS, cold-insoluble globulin
Source: HGNC:3778
Biotype: protein coding gene
PSME4
(Homo sapiens)Gene
Name: proteasome activator subunit 4
Synonyms: MGC138374, PA200, proteasome activator 200 kDa, Blm10, hBlm10, proteasome activator PA200, FLJ21864, KIAA0077, proteasome (prosome, macropain) activator subunit 4, proteasome activator complex subunit 4, MGC142228
Source: HGNC:20635
Biotype: protein coding gene
CASP8
(Homo sapiens)Gene
Name: caspase 8
Synonyms: ALPS2B, caspase-8, apoptotic cysteine protease, caspase 8, apoptosis-related cysteine peptidase, MCH5, caspase 8, apoptosis-related cysteine protease, Casp-8, MORT1-associated ced-3 homolog, FADD-homologous ICE/CED-3-like protease, MGC78473, FADD-like ICE, MACH-beta-1/2/3/4 protein, MACH-alpha-1/2/3 protein, FLJ17672, MACH, apoptotic protease Mch-5, FLICE, ICE-like apoptotic protease 5, CAP4
Source: HGNC:1509
Biotype: protein coding gene
Ctsh
(Mus musculus)Gene
Name: cathepsin H
Synonyms: Cat H, expressed sequence AL022844, AL022844
Source: MGI:107285
Biotype: protein coding gene
NLRP1
(Homo sapiens)Gene
Name: NLR family pyrin domain containing 1
Synonyms: VAMAS1, caspase recruitment domain-containing protein 7, NACHT, LRR and PYD domains-containing protein 1, systemic lupus erythematosus, vitiligo-related 1, SLEV1, AIADK, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1, DEFCAP, PP1044, DEFCAP-L/S, JRRP, NACHT, leucine rich repeat and PYD (pyrin domain) containing 1, CARD7, DKFZp586O1822, death effector filament-forming Ced-4-like apoptosis protein, NLR family, pyrin domain containing 1, NACHT, LRR and PYD containing protein 1, CIDED, nucleotide-binding domain and caspase recruitment domain, NAC, caspase recruitment domain protein 7, NALP1, NACHT, leucine rich repeat and PYD containing 1, MSPC, CLR17.1, KIAA0926
Source: HGNC:14374
Biotype: protein coding gene
Nlrp3
(Mus musculus)Gene
Name: NLR family, pyrin domain containing 3
Synonyms: cryopyrin, Mmig1, Pypaf1, cold autoinflammatory syndrome 1 homolog (human), NALP3, Cias1
Source: MGI:2653833
Biotype: protein coding gene
TGFB1
(Homo sapiens)Gene
Name: transforming growth factor beta 1
Synonyms: prepro-transforming growth factor beta-1, CED, TGFB, TGF-beta 1 protein, TGF-beta-1, latency-associated peptide, IBDIMDE, DPD1, transforming growth factor beta1, LAP, transforming growth factor beta-1, transforming growth factor beta-1 proprotein, TGF-beta1, TGFbeta
Source: HGNC:11766
Biotype: protein coding gene
PINK1
(Homo sapiens)Gene
Name: PTEN induced kinase 1
Synonyms: FLJ27236, serine/threonine-protein kinase PINK1, mitochondrial, Parkinson disease (autosomal recessive) 6, BRPK, PTEN induced putative kinase 1, PTEN-induced putative kinase protein 1, protein kinase BRPK, PARK6
Source: HGNC:14581
Biotype: protein coding gene
NGF
(Homo sapiens)Gene
Name: nerve growth factor
Synonyms: HSAN5, MGC161428, Beta-NGF, nerve growth factor, beta polypeptide, NGFB, MGC161426, beta-nerve growth factor, pro-nerve growth factor long, nerve growth factor (beta polypeptide), nerve growth factor, beta subunit
Source: HGNC:7808
Biotype: protein coding gene
Vcp
(Rattus norvegicus)Gene
Name: valosin-containing protein
Synonyms: 15S Mg(2+)-ATPase p97 subunit, TER ATPase, transitional endoplasmic reticulum ATPase
Source: RGD:621595
Biotype: protein coding gene
CTSL
(Homo sapiens)Gene
Name: cathepsin L
Synonyms: CTSL1, procathepsin L, MEP, CATL, FLJ31037, cathepsin L1, major excreted protein
Source: HGNC:2537
Biotype: protein coding gene
MALT1
(Homo sapiens)Gene
Name: MALT1 paracaspase
Synonyms: mucosa associated lymphoid tissue lymphoma translocation gene 1, MALT1 protease, DKFZp434L132, caspase-like protein, paracaspase 1, IMD12, paracaspase-1, MALT lymphoma-associated translocation, MLT, PCASP1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, MLT1, MALT-lymphoma associated translocation, paracaspase, MALT associated translocation
Source: HGNC:6819
Biotype: protein coding gene
PRE1
(Saccharomyces cerevisiae)Gene
Name: PRoteinase yscE
Synonyms: YER012W
Source: SGD:S000000814
Biotype: protein coding gene
App
(Rattus norvegicus)Gene
Name: amyloid beta precursor protein
Synonyms: amyloid beta (A4) precursor protein, Abeta, amyloid beta A4 protein, AG, alzheimer disease amyloid A4 protein homolog, amyloidogenic glycoprotein, amyloid A4, ABPP
Source: RGD:2139
Biotype: protein coding gene
APH1A
(Homo sapiens)Gene
Name: aph-1 homolog A, gamma-secretase subunit
Synonyms: aph-1 homolog A, gamma secretase subunit, 6530402N02Rik, APH-1, anterior pharynx defective 1 homolog A, presenilin-stabilization factor, CGI-78, APH-1A, APH1A gamma secretase subunit, gamma-secretase subunit APH-1A, aph-1alpha
Source: HGNC:29509
Biotype: protein coding gene
PSMD14
(Homo sapiens)Gene
Name: proteasome 26S subunit, non-ATPase 14
Synonyms: proteasome (prosome, macropain) 26S subunit, non-ATPase, 14, 26S proteasome non-ATPase regulatory subunit 14, 26S proteasome-associated PAD1 homolog 1, RPN11, 26S proteasome regulatory subunit rpn11, PAD1, testis tissue sperm-binding protein Li 69n, POH1
Source: HGNC:16889
Biotype: protein coding gene
CTSC
(Homo sapiens)Gene
Name: cathepsin C
Synonyms: DPP-I, DPPI, JP, dipeptidyl-peptidase I, DPP1, HMS, dipeptidyl peptidase I, juvenile periodontitis, PLS, dipeptidyl peptidase 1, CPPI, PDON1, dipeptidyl transferase, PALS, cathepsin J, JPD
Source: HGNC:2528
Biotype: protein coding gene
Vsir
(Mus musculus)Gene
Name: V-set immunoregulatory receptor
Synonyms: Dies1, VISTA, RIKEN cDNA 4632428N05 gene, PD-1H, 4632428N05Rik
Source: MGI:1921298
Biotype: protein coding gene
Cav1
(Rattus norvegicus)Gene
Name: caveolin 1
Synonyms: caveolin-1, Caveolin, caveolae protein, 22 kDa, Caveolin caveolae protein 22 kDa, caveolin 1, caveolae protein, Cav, caveolin, caveolae protein 1, MGC187299, LOC100362870, caveolin-like, caveolin
Source: RGD:2280
Biotype: protein coding gene
CTSH
(Homo sapiens)Gene
Name: cathepsin H
Synonyms: cathepsin B3, CPSB, pro-cathepsin H, ACC5, ACC4, DKFZp686B24257, cathepsin BA, minichain, N-benzoylarginine-beta-naphthylamide hydrolase, ACC-5, MGC1519, ACC-4, aleurain
Source: HGNC:2535
Biotype: protein coding gene
Vcp
(Mus musculus)Gene
Name: valosin containing protein
Synonyms: AAA ATPase p97, CDC48, p97/VCP, p97
Source: MGI:99919
Biotype: protein coding gene
ScsβA
(Drosophila melanogaster)Gene
Name: Succinyl-coenzyme A synthetase beta subunit, ADP-forming
Synonyms: ATP-specific SCSbeta, Skap, SkAP, CG11963, ATP-specific form of the succinyl-CoA synthetase beta subunit, SkpA Associated Protein, skpA-associated protein, A-Sbeta, succinyl CoA synthetase, FBgn0037643, skap, CGI 1963, SkpA-associated protein, skpA associated protein
Source: FB:FBgn0037643
Biotype: protein coding gene
Ctsh
(Rattus norvegicus)Gene
Name: cathepsin H
Synonyms: cathepsin B3, cathepsin BA, pro-cathepsin H
Source: RGD:2447
Biotype: protein coding gene
Svbp
(Mus musculus)Gene
Name: small vasohibin binding protein
Synonyms: 2410005K17Rik, RIKEN cDNA 2410005K17 gene, RGD1311232, AI851162, Ccdc23, expressed sequence AI851162, coiled-coil domain containing 23
Source: MGI:1916466
Biotype: protein coding gene
BCL2L13
(Homo sapiens)Gene
Name: BCL2 like 13
Synonyms: BCL-RAMBO, Bcl2-L-13, MIL1, BCL2-like 13 (apoptosis facilitator), bcl-2-like protein 13
Source: HGNC:17164
Biotype: protein coding gene
Ngf
(Mus musculus)Gene
Name: nerve growth factor
Synonyms: Ngfb, nerve growth factor, beta, beta-NGF
Source: MGI:97321
Biotype: protein coding gene
Bad
(Mus musculus)Gene
Name: BCL2-associated agonist of cell death
Synonyms: Bbc2, Bad_v1, Bad_v2, AI325008, expressed sequence AI325008
Source: MGI:1096330
Biotype: protein coding gene
Malt1
(Mus musculus)Gene
Name: MALT1 paracaspase
Synonyms: Pcasp1, RIKEN cDNA D430033E09 gene, D430033E09Rik, paracaspase
Source: MGI:2445027
Biotype: protein coding gene
Casp8
(Mus musculus)Gene
Name: caspase 8
Synonyms: Caspase-8, Mch5, CASP-8, MACH, FLICE
Source: MGI:1261423
Biotype: protein coding gene
psme-3
(Caenorhabditis elegans)Gene
Name: ProteaSoME activator subunit 3
Synonyms: CELE_Y66D12A.9, Y66D12A.9
Source: WB:WBGene00013435
Biotype: protein coding gene
CARD8
(Homo sapiens)Gene
Name: caspase recruitment domain family member 8
Synonyms: CARD inhibitor of NF-kappaB-activating ligands, caspase recruitment domain-containing protein 8, TUCAN, DACAR, MGC57162, DKFZp779L0366, caspase recruitment domain family, member 8, NDPP1, CARDINAL, FLJ18119, apoptotic protein NDPP1, NDPP, KIAA0955, tumor up-regulated CARD-containing antagonist of CASP9, Dakar, FLJ18121, tumor up-regulated CARD-containing antagonist of caspase nine
Source: HGNC:17057
Biotype: protein coding gene
Svbp
(Rattus norvegicus)Gene
Name: small vasohibin binding protein
Synonyms: LOC362578, RGD1311232, Ccdc23, similar to RIKEN cDNA 2410005K17, MGC116404, coiled-coil domain-containing protein 23, coiled coil domain-containing protein 23, coiled-coil domain containing 23
Source: RGD:1311232
Biotype: protein coding gene
Pycard
(Mus musculus)Gene
Name: PYD and CARD domain containing
Synonyms: Asc, 9130417A21Rik, TMS-1, RIKEN cDNA 9130417A21 gene
Source: MGI:1931465
Biotype: protein coding gene
Tnfrsf10b
(Mus musculus)Gene
Name: tumor necrosis factor receptor superfamily, member 10b
Synonyms: TRAIL-R2, TRICKB, DR5, Killer/Dr5, Ly98, KILLER, Trail Receptor, TRAILR2, TRICK2B, TRICK2A
Source: MGI:1341090
Biotype: protein coding gene
Rack1
(Mus musculus)Gene
Name: receptor for activated C kinase 1
Synonyms: guanine nucleotide binding protein, beta-2, related sequence 1, p205, Gnb2-rs1, guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1, guanine nucleotide binding protein, beta 2, related sequence 1, GB-like, Gnb2l1
Source: MGI:101849
Biotype: protein coding gene
PUP3
(Saccharomyces cerevisiae)Gene
Name: PUtative Proteasome subunit
Synonyms: SCS32, YER094C
Source: SGD:S000000896
Biotype: protein coding gene
SVBP
(Homo sapiens)Gene
Name: small vasohibin binding protein
Synonyms: CCDC23, coiled-coil domain-containing protein 23, coiled-coil domain containing 23, coiled coil domain-containing protein 23, NEDAHM
Source: HGNC:29204
Biotype: protein coding gene
FBLN1
(Homo sapiens)Gene
Name: fibulin 1
Synonyms: fibulin-1, FIBL1, FBLN
Source: HGNC:3600
Biotype: protein coding gene
CASP1
(Homo sapiens)Gene
Name: caspase 1
Synonyms: caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase), interleukin 1-beta convertase, interleukin-1 beta convertase, IL1BC, ICE, interleukin 1-B converting enzyme, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), caspase-1 isoform alpha, P45, CASP-1, interleukin 1, beta, convertase, IL-1 beta-converting enzyme, IL-1BC, caspase-1, caspase 1, apoptosis-related cysteine peptidase, IL1B-convertase, CASP1 nirs variant 1, interleukin-1 beta-converting enzyme
Source: HGNC:1499
Biotype: protein coding gene
Nlrc4
(Mus musculus)Gene
Name: NLR family, CARD domain containing 4
Synonyms: RIKEN cDNA 9530011P19 gene, Card12, 9530011P19Rik, caspase recruitment domain family, member 12, Ipaf
Source: MGI:3036243
Biotype: protein coding gene