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925 results for ddx3x

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Ddx3x

(Mus musculus)

Gene

Name: DEAD box helicase 3, X-linked

Synonyms: D1Pas1 related sequence 2, fibroblast growth factor inducible 14, Fin14, embryonic RNA helicase, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked, D1Pas1-rs2, Ddx3

Source: MGI:103064

Biotype: protein coding gene

Symbol: Ddx3x (Mmu)

Symbol: Ddx3x

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).

Strict Orthology Symbols: ddx3x

Alleles: Ddx3x (Mmu)...Ddx3x (Mmu)...Ddx3x (Mmu)...Ddx3x (Mmu)...Ddx3x (Mmu)

DDX3X

(Homo sapiens)

Gene

Name: DEAD-box helicase 3 X-linked

Synonyms: DEAD box, X isoform, CAP-Rf, DEAD box protein 3, X-chromosomal, DDX3, DDX14, HLP2, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked, ATP-dependent RNA helicase DDX3X, MRX102, helicase-like protein 2, DEAD-box helicase 3, X-linked, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked, helicase like protein 2, DBX, DEAD/H box-3, MRXSSB

Source: HGNC:2745

Biotype: protein coding gene

Symbol: DDX3X (Hsa)

Symbol: DDX3X

Synonyms: ATP-dependent RNA helicase DDX3X

Strict Orthology Symbols: ddx3x

Ddx3x

(Rattus norvegicus)

Gene

Name: DEAD-box helicase 3, X-linked

Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked, DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked, ATP-dependent RNA helicase DDX3X

Source: RGD:1564771

Biotype: protein coding gene

Symbol: Ddx3x (Rno)

Symbol: Ddx3x

Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked); PARTICIPATES IN Retinoic acid-inducible gene

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).

Synonyms: ATP-dependent RNA helicase DDX3X

Strict Orthology Symbols: ddx3x

ddx3x

(Xenopus tropicalis)

Gene

Name: DEAD-box helicase 3 X-linked

Synonyms: DEAD-box helicase 3 X-linked, An3, ddx3x

Source: Xenbase:XB-GENE-999731

Biotype: gene

Symbol: ddx3x (Xtr)

Symbol: ddx3x

Automated Gene Synopsis: Orthologous to several human genes including DDX3X (DEAD-box helicase 3 X-linked).

Synonyms: ddx3x...ddx3x...ddx3x

Strict Orthology Symbols: DDX3X...ddx3x.S...Ddx3x...ddx3xb...ddx3xa

Disease (5)

ddx3xa

(Danio rerio)

Gene

Name: DEAD-box helicase 3 X-linked a

Synonyms: fb74g09, zgc:158804, ddx3, ddx3a, wu:fb74g09

Source: ZFIN:ZDB-GENE-030131-1565

Biotype: protein coding gene

Symbol: ddx3xa (Dre)

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).

Strict Orthology Symbols: ddx3x

Symbol: ddx3xa

ddx3xb

(Danio rerio)

Gene

Name: DEAD-box helicase 3 X-linked b

Synonyms: p110a, ddx3b, pl10a, wu:fb43h11, wu:fy72b06, pl10, etID309900.24

Source: ZFIN:ZDB-GENE-980526-150

Biotype: protein coding gene

Symbol: ddx3xb (Dre)

Automated Gene Synopsis: Orthologous to several human genes including DDX3X (DEAD-box helicase 3 X-linked).

Strict Orthology Symbols: ddx3x

Symbol: ddx3xb

ddx3x.S

(Xenopus laevis)

Gene

Name: DEAD-box helicase 3 X-linked

Synonyms: ddx3x.S, An3, DEAD-box helicase 3 X-linked

Source: Xenbase:XB-GENE-17330554

Biotype: gene

Symbol: ddx3x.S (Xla)

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).

Strict Orthology Symbols: ddx3x

Symbol: ddx3x.S

Disease (3)

ddx3x.L

(Xenopus laevis)

Gene

Name: DEAD-box helicase 3 X-linked

Synonyms: An3, DEAD-box helicase 3 X-linked, ddx3x.L

Source: Xenbase:XB-GENE-999738

Biotype: gene

Symbol: ddx3x.L (Xla)

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).

Strict Orthology Symbols: ddx3x

Symbol: ddx3x.L

Disease (3)

Ddx3x^tm1.2Lyou

(Mus musculus)

Allele/Variant

Source: MGI:5774969

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^tm1.2Lyou

Ddx3x^em1.1Tdk

(Mus musculus)

Allele/Variant

Source: MGI:6466746

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^em1.1Tdk

Gene (1)

Ddx3x^tm1Pngr

(Mus musculus)

Allele/Variant

Source: MGI:7482466

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^tm1Pngr

Gene (1)

Ddx3x^em1Lutzy

(Mus musculus)

Allele/Variant

Source: MGI:6798132

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^em1Lutzy

Gene (1)

Ddx3x^em2Cya

(Mus musculus)

Allele/Variant

Source: MGI:7583349

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^em2Cya

Gene (1)

Ddx3x^em1Osb

(Mus musculus)

Allele/Variant

Source: MGI:6323446

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^em1Osb

Ddx3x^tm1Tmo

(Mus musculus)

Allele/Variant

Source: MGI:7335163

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^tm1Tmo

Gene (1)

Ddx3x^tm1.1Lyou

(Mus musculus)

Allele/Variant

Source: MGI:5774968

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^tm1.1Lyou

Ddx3x^tm1.1Sdru

(Mus musculus)

Allele/Variant

Source: MGI:7425293

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^tm1.1Sdru

Gene (1)

Ddx3x^em1Tdk

(Mus musculus)

Allele/Variant

Source: MGI:6466745

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^em1Tdk

Gene (1)

Ddx3x^em2Osb

(Mus musculus)

Allele/Variant

Source: MGI:6323448

Genes: Ddx3x (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Ddx3x (Mmu)

Genes: Ddx3x (Mmu)

Symbol: Ddx3x^em2Osb

Ddx3x-ps1

(Rattus norvegicus)

Gene

Name: DEAD-box helicase 3, X-linked, pseudogene 1

Synonyms: LOC498906, similar to ATP-dependent RNA helicase DDX3X, similar to ATP-dependent RNA helicase DDX3X (DEAD box protein 3, X-chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform)

Source: RGD:1586041

Biotype: pseudogene

Symbol: Ddx3x-ps1 (Rno)

Synonyms: similar to ATP-dependent RNA helicase DDX3X...similar to ATP-dependent RNA helicase DDX3X (DEAD box protein 3, X-chromosomal) (Helicase-like protein

Symbol: Ddx3x-ps1

Ddx3x^tm1.2Lyou/Y [background:] involves: 129 * C57BL/6

(Mus musculus)

Model

Id: MGI:5774970

Synonyms: Not Available

Symbol: Ddx3x/Y [background:] involves: 129 * C57BL/6 (Mmu)

Genes: Ddx3x (Mmu)

Alleles: Ddx3x (Mmu)

Name: Ddx3x/Y [background:] involves: 129 * C57BL/6

Gene (1)

Ddx3x^tm1.1Lyou/Y Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ [background:] involves: 129 * C57BL/6 * CBA

(Mus musculus)

Model

Id: MGI:5774972

Synonyms: Not Available

Symbol: Ddx3x/Y Edil3/Edil3<+> [background:] involves: 129 * C57BL/6 * CBA (Mmu

Genes: Ddx3x (Mmu)

Alleles: Ddx3x (Mmu)

Name: Ddx3x/Y Edil3/Edil3<+> [background:] involves: 129 * C57BL/6 * CBA

Gene (2)

DDX3X suppresses neural lineage susceptibility to medulloblastoma [RNA-seq]

(Mus musculus)

HTP Dataset Index

High-Throughput (HTP) Dataset Index metadata provided by MGI

ID: ArrayExpress:GSE147178

Tags: WT vs. mutant, age, developmental stage, genotype

Summary: DDX3X is frequently mutated in the WNT and SHH subtypes of medulloblastom-the commonest malignant childhood brain tumor. But whether DDX3X functions as a medulloblastoma oncogene or tumor suppressor gene is not known. Here we show that Ddx3x regulates hindbrain patterning and development by controlling Hox gene expression and cell stress signaling. In mice predisposed to Wnt or Shh-medulloblastoma Ddx3x sensed oncogenic stress and suppressed tumor formation. WNT and SHH-medulloblastomas normally arise only in the lower and upper rhombic lips respectively. Deletion of Ddx3x relived this lineage restriction enabling both medulloblastoma subtypes to arise in either germinal zone. Thus DDX3X is a medulloblastoma tumor suppressor that regulates hindbrain development and restricts the competence of cell lineages to form medulloblastoma subtypes. RNA-sequencing profiles of developmental time points in the cerebullum of WT and DDX3X perturbed Blbp positive cells and in tumors formed from aberrant Wnt or Shh signalling. BCP and BPtcH DO NOT have DDX3X perturbations. 3 to 5 replicates per time point per condition.

Symbol: DDX3X suppresses neural lineage susceptibility to medulloblastoma [RNA-seq]

Name: DDX3X suppresses neural lineage susceptibility to medulloblastoma [RNA-seq]

Ddx3x^tm1.1Lyou/Ddx3x⁺ Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ [background:] involves: 129 * C57BL/6 * CBA

(Mus musculus)

Model

Id: MGI:5774973

Synonyms: Not Available

Symbol: Ddx3x/Ddx3x<+> Edil3/Edil3<+> [background:] involves: 129 * C57BL/6 * CBA

Genes: Ddx3x (Mmu)

Alleles: Ddx3x (Mmu)

Name: Ddx3x/Ddx3x<+> Edil3/Edil3<+> [background:] involves: 129 * C57BL/6 * CBA

Gene (2)

Ddx3x^em1Osb/Y X/Ddx3y^em2Osb [background:] involves: C57BL/6NJcl * DBA/2NJcl

(Mus musculus)

Model

Id: MGI:6379312

Synonyms: Not Available

Symbol: Ddx3x/Y X/Ddx3y [background:] involves: C57BL/6NJcl * DBA/2NJcl (Mmu)

Genes: Ddx3x (Mmu)

Alleles: Ddx3x (Mmu)

Name: Ddx3x/Y X/Ddx3y [background:] involves: C57BL/6NJcl * DBA/2NJcl

Gene (2)

Ddx3x^em2Osb/Y X/Ddx3y^em1Osb [background:] chimera involves: 129S2/SvPas * C57BL/6NSlc

(Mus musculus)

Model

Id: MGI:6379314

Synonyms: Not Available

Symbol: Ddx3x/Y X/Ddx3y [background:] chimera involves: 129S2/SvPas * C57BL/6NSlc (Mmu)

Genes: Ddx3x (Mmu)

Alleles: Ddx3x (Mmu)

Name: Ddx3x/Y X/Ddx3y [background:] chimera involves: 129S2/SvPas * C57BL/6NSlc

Gene (2)

Ddx3x^tm1.2Lyou/Ddx3x⁺ [background:] involves: 129 * C57BL/6

(Mus musculus)

Model

Id: MGI:5774971

Synonyms: Not Available

Symbol: Ddx3x/Ddx3x<+> [background:] involves: 129 * C57BL/6 (Mmu)

Genes: Ddx3x (Mmu)

Alleles: Ddx3x (Mmu)

Name: Ddx3x/Ddx3x<+> [background:] involves: 129 * C57BL/6

Gene (1)

vbh-1

(Caenorhabditis elegans)

Gene

Name: Vasa- and Belle-like Helicase 1

Synonyms: Y54E10A.9, CELE_Y54E10A.9

Source: WB:WBGene00006888

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).

Strict Orthology Symbols: ddx3x

Ddx3

(Rattus norvegicus)

Gene

Name: DEAD-box helicase 3

Synonyms: DEAD-box helicase 3, Y-linked, RGD1309586, similar to probable ATP-dependent RNA helicase - mouse, Ddx3y, Putative ATP-dependent RNA helicase Pl10-like, hypothetical protein LOC364073, DEAD-box helicase 3, Y-linked like, DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked, uncharacterized protein LOC364073, Ddx3yl, LOC364073

Source: RGD:1309586

Biotype: protein coding gene

Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked); PARTICIPATES IN Retinoic acid-inducible gene

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).

Strict Orthology Symbols: ddx3x

DBP1

(Saccharomyces cerevisiae)

Gene

Name: Dead Box Protein

Synonyms: LPH8, YPL119C

Source: SGD:S000006040

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked) and DDX3Y (DEAD-box helicase 3 Y-linked).

Strict Orthology Symbols: ddx3x

D1Pas1

(Mus musculus)

Gene

Name: DNA segment, Chr 1, Pasteur Institute 1

Synonyms: RGD1309586, AU016353, Ddx3yl, Pl10, expressed sequence AU016353

Source: MGI:91842

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).

Strict Orthology Symbols: ddx3x

DDX3Y

(Homo sapiens)

Gene

Name: DEAD-box helicase 3 Y-linked

Synonyms: DEAD-box helicase 3, Y-linked, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked, DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked, DEAD box protein 3, Y-chromosomal, DBY, ATP-dependent RNA helicase DDX3Y

Source: HGNC:2699

Biotype: protein coding gene

Gene Synopsis: Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and

Strict Orthology Symbols: ddx3x

Disease (2)

laf-1

(Caenorhabditis elegans)

Gene

Name: Lethal And Feminizing 1

Synonyms: CELE_Y71H2AM.19, Y71H2AM.19

Source: WB:WBGene00002244

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked) and DDX3Y (DEAD-box helicase 3 Y-linked).

Strict Orthology Symbols: ddx3x

DED1

(Saccharomyces cerevisiae)

Gene

Name: Defines Essential Domain

Synonyms: YOR204W, SPP81

Source: SGD:S000005730

Biotype: protein coding gene

Gene Synopsis: complex disassembly; mutation in human homolog DBY associated with male infertility; human homolog DDX3X

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked) and DDX3Y (DEAD-box helicase 3 Y-linked).

Strict Orthology Symbols: ddx3x

bel

(Drosophila melanogaster)

Gene

Name: belle

Synonyms: BELLE, psg9, DDX3, DmRH6, L3, BEL, Bel, l(3)85Ac, lethal (3) S047110, l(3)L3, l(3)L4740, capon, CG9748, ms(3)Pneo85A, l(3)S097074, cap, anon-85Ab, Belle, cg9748, l(3)S047110, belle, ms(3)neo30, lethal (3) L4740

Source: FB:FBgn0263231

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human DDX3X (DEAD-box helicase 3 X-linked) and DDX3Y (DEAD-box helicase 3 Y-linked).

Strict Orthology Symbols: ddx3x

Ddx3y

(Mus musculus)

Gene

Name: DEAD box helicase 3, Y-linked

Synonyms: DNA segment, Chr 1, Pasteur Institute 1, related sequence 1, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide, Y chromosome, D1Pas1-rs1, RIKEN cDNA 8030469F12 gene, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked, Dby, Ddx3, 8030469F12Rik

Source: MGI:1349406

Biotype: protein coding gene

Strict Orthology Symbols: ddx3x

Ddx3y

(Rattus norvegicus)

Gene

Name: DEAD box helicase 3, Y-linked

Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 Y-linked, Ddx3, ATP-dependent RNA helicase DDX3Y

Source: RGD:2314437

Biotype: protein coding gene

Strict Orthology Symbols: ddx3x