Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: establishment of localization Molecular Function: small molecule binding
BRCA1
(Homo sapiens)Gene
Name: BRCA1 DNA repair associated
Synonyms: RNF53, early onset breast cancer 1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast cancer 1, BRCC1, BRCA1, DNA repair associated, RING finger protein 53, breast and ovarian cancer susceptibility protein 1, BRCA1/BRCA2-containing complex, subunit 1, breast cancer 1, early onset, IRIS, Fanconi anemia, complementation group S, breast cancer type 1 susceptibility protein, BRCAI, PNCA4, PSCP, truncated BRCA1, BROVCA1, protein phosphatase 1, regulatory subunit 53, breast cancer 1, PPP1R53, FANCS
Source: HGNC:1100
Biotype: protein coding gene
HLA-A
(Homo sapiens)Gene
Name: major histocompatibility complex, class I, A
Synonyms: HLA class I histocompatibility antigen, A-1 alpha chain, HLA A, HLAA, MHC class I antigen A*34, MHC class I antigen A*33, HLA class I histocompatibility antigen, A-43 alpha chain, MHC class I antigen A*32, MHC class I antigen A*31, HLA-A11, MHC class II antigen, HLA class I histocompatibility antigen, A-80 alpha chain, MHC class I antigen A*36, HLA class I histocompatibility antigen, A-23 alpha chain, HLA class I histocompatibility antigen, A-66 alpha chain, HLA class I histocompatibility antigen, A-9 alpha chain, aw-19, MHC class I antigen HLA-A33, truncated MHC class I antigen, MHC class I antigen A*30, MHC class I antigen A*74, MHC class I antigen A*1, leucocyte antigen A, HLA-Aw33.1, MHC class I antigen A*43, MHC class I anti, MHC class I antigen HLA-A heavy chain, HLA class I histocompatibility antigen, A-69 alpha chain-like, HLA class I histocompatibility antigen, A-26 alpha chain, HLA class I histocompatibility antigen, A-36 alpha chain, MHC class I antigen A*80, HLA class I histocompatibility antigen, A-28 alpha chain, aw-24, HLA class I histocompatibility antigen, A-24 alpha chain, HLA class I histocompatibility antigen, A-25 alpha chain, HLA class I histocompatibility antigen, A-29 alpha chain, aw-66, LOC100507703, leucocyte antigen class I, HLA-DQB1, MHC class I antigene, antigen presenting molecule, HLA class I antigen, FLJ26655, HLA class I histocompatibility antigen, A-31 alpha chain, MHC leukocyte antigen, HLA class I histocompatibility antigen, A-10 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, MHC class I antigen A*11, HLA-A33, HLA class I histocompatibility antigen, A-34 alpha chain, Aw-69, HLA-A locus alpha 2 domain, Aw-68, aw-34, leukocyte antigen class I-A, aw-36, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, MHC class I antigen heavy chain, MHC class I antigen A*29, aw-80, MHC class I antigen A*2, MCH class I antigen, MHC class I antigen A*3, MHC class I antigen A*23, HLA-A null, MHC class I antigen A*66, MHC class I antigen A*26, MHC class I antigen A*69, MHC class I antigen A*25, MHC class I antigen A*24, MHC class I antigen A*68, MHC classI antigen, HLA locus, HLA class I histocompatibility antigen, A alpha chain, MHC Class I antigen, MHC class 1 antigen, aw-43, Aw-33, Aw-74, HLA-DRB1
Source: HGNC:4931
Biotype: protein coding gene
TYR
(Homo sapiens)Gene
Name: tyrosinase
Synonyms: SHEP3, OCA1, tumor rejection antigen AB, LB24-AB, SK29-AB, OCA1A, oculocutaneous albinism IA, CMM8, ATN, OCAIA, monophenol monooxygenase
Source: HGNC:12442
Biotype: protein coding gene
HOG1
(Saccharomyces cerevisiae)Gene
Name: High Osmolarity Glycerol response
Synonyms: YLR113W, SSK3
Source: SGD:S000004103
Biotype: protein coding gene
ADE2
(Saccharomyces cerevisiae)Gene
Name: ADEnine requiring
Synonyms: YOR128C
Source: SGD:S000005654
Biotype: protein coding gene
Gapdh
(Mus musculus)Gene
Name: glyceraldehyde-3-phosphate dehydrogenase
Synonyms: cDNA sequence AK190093, BARS-38, AK190093, Gapd
Source: MGI:95640
Biotype: protein coding gene
Mpo
(Mus musculus)Gene
Name: myeloperoxidase
Synonyms: Not Available
Source: MGI:97137
Biotype: protein coding gene
RAD27
(Saccharomyces cerevisiae)Gene
Name: RADiation sensitive
Synonyms: FEN1, ERC11, YKL113C, RTH1
Source: SGD:S000001596
Biotype: protein coding gene
ERCC5
(Homo sapiens)Gene
Name: ERCC excision repair 5, endonuclease
Synonyms: xeroderma pigmentosum, complementation group G, ERCC5-201, UVDR, ERCM2, xeroderma pigmentosum group G-complementing protein, XPG, COFS3, excision repair protein, excision repair cross-complementing rodent repair deficiency, complementation group 5, DNA repair protein complementing XP-G cells, excision repair cross-complementation group 5, XPG-complementing protein, DNA excision repair protein ERCC-5, XPGC, xeroderma pigmentosum complementation group G protein
Source: HGNC:3437
Biotype: protein coding gene
KRAS
(Homo sapiens)Gene
Name: KRAS proto-oncogene, GTPase
Synonyms: KI-RAS, RALD, NS, c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, PR310 c-K-ras oncogene, KRAS-ENOPH fusion, K-RAS2B, GTPase KRas, K-RAS2A, NS3, K-RAS4B, K-RAS4A, c-Kirsten-ras protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, Kirsten rat sarcoma viral proto-oncogene, c-Ki-ras, Kirsten rat sarcoma viral oncogene homolog, oncogene KRAS2, K-ras p21 protein, RASK2, CFC2, K-Ras, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, C-K-RAS, K-Ras 2, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, OES, cellular transforming proto-oncogene, KRAS2, 'C-K-RAS, proto-oncogene GTPase, transforming protein p21, KRAS1
Source: HGNC:6407
Biotype: protein coding gene
DMD
(Homo sapiens)Gene
Name: dystrophin
Synonyms: truncated dystrophin, DXS270, mutant dystrophin, dystrophin (muscular dystrophy, Duchenne and Becker types), DXS272, mental retardation, X-linked 85, DXS239, DXS206, MRX85, BMD, DXS142, DXS230, DXS164, DXS268, CMD3B, DXS269
Source: HGNC:2928
Biotype: protein coding gene
SIRT1
(Homo sapiens)Gene
Name: sirtuin 1
Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, regulatory protein SIR2 homolog 1, hSIRT1, hSIR2, sirtuin type 1, NAD-dependent deacetylase sirtuin-1
Source: HGNC:14929
Biotype: protein coding gene
FGFR3
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 3
Synonyms: tyrosine kinase JTK4, JTK4, HSFGFR3EX, ACH, CEK2, fibroblast growth factor receptor 3 variant 4, achondroplasia, thanatophoric dwarfism, CD333, fibroblast growth factor receptor 3-S, hydroxyaryl-protein kinase, FGFR-3
Source: HGNC:3690
Biotype: protein coding gene
F9
(Homo sapiens)Gene
Name: coagulation factor IX
Synonyms: plasma thromboplastin component, F9 p22, MGC129642, MGC129641, coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B), coagulation factor 9, serine protease, THPH8, factor 9, HEMB, FIX, Christmas factor, P19, factor IX F9, plasma thromboplastic component, FIX F9, PTC
Source: HGNC:3551
Biotype: protein coding gene
HLA-B
(Homo sapiens)Gene
Name: major histocompatibility complex, class I, B
Synonyms: Bw-45, MHC HLA-B27-HS, HLA-B39, Bw-47, Bw-48, MHC Class I HLA heavy chain, HLAB, HLAC, MHC class I antigen B*46, HLA class I histocompatibility antigen, B-73 alpha chain, MHC class I antigen B*45, MHC class I antigen B*44, HLA-Bw45 antigen, MHC class II antigen, HLA-B*45ZJ, MHC class I antigen B*49, HLA-B35, MHC class I antigen B*48, MHC class I antigen B*47, MHC class I antigen HLA-B heavy chain, MHC class I antigen B*42, MHC class I antigen B*41, MGC111087, MHC class I antigen B*40, HLA B-40011, HLA-B alpha chain (B*5002), MHC class I antigen B*7, Bw-56, MHC class I antigen B*8, Bw-58, bw-22, HLA class I histocompatibility antigen, B-5 alpha chain, MHC class I antigen B*57, HLA-C, MHC class I antigen B*56, MHC HLA-B cell surface glycoprotein, MHC class I antigen B*55, Bw-50, HLA class I histocompatibility antigen, B-8 alpha chain, MHC class I antigen B*54, HLA-B49, MHC class I antigen B*59, MHC class I antigen B*58, HLA class I histocompatibility antigen, B-7 alpha chain, AS, MHC class I antigen B*53, MHC class I antigen B*52, MHC class I antigen B*51, MHC class I antigen B*50, HLA-Bw50 antigen, HLA class I histocompatibility antigen, B-67 alpha chain, HLA class I histocompatibility antigen, B-45 alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA molecule, ankylosing spondylitis, HLA-B55, MHC class I antigen B*67, HLA-B-7301, HLA B44, HLA-B59, HLA class I histocompatibility antigen, B-48 alpha chain, MHC class I antigen Cw*5, HLA-B50, HLA class I histocompatibility antigen, B-21 alpha chain, HEL-S-83, SPDA1, bw-46, bw-44, HLA-B-3905, MHC class I antigen B*78, HLA-B-3506, bw-41, MHC class l antigen, HLA class I histocompatibility antigen, B-82 alpha chain, MHC class I antigen B*73, HLA-B alpha chain (HLA-B*7301), HLA-B61, b'DT, MHC class 1 antigen, lecocyte antigen B, HLA-DRB1, bw-57, HLA class I histocompatibility antigen, B-56 alpha chain, bw-55, histocompatibility antigen, bw-54, bw-53, HLA-B-5502, bw-52, HLA-Cw, Leukocyte Antigen, HLA class I histocompatibility antigen, B-59 alpha chain, MHC class I antigen B*82, MHC class I antigen B*81, HLA-B*5901 antigen, bw-4, MHC antigen, truncated MHC class I antigen, HLA-B73, MHC class I antigen GN00104, HLA class I histocompatibility antigen, B-12 alpha chain, epididymis secretory protein Li 83, MHC class I antigen B*18, MHC class I antigen B*13, bw-60, HLA class I antigen HLA-B, MHC class I antigen B*15, MHC class I antigen B*14, class I MHC, HLA-B antigen, truncated class I antigen, B-5001, MHC HLA-B transmembrane glycoprotein, MHC class I human leukocyte antigen, MHC class I molecule, MHC class I antigene, B-4901, Leukoocyte Antigen, HLA-B15, MHC class I antigen B*27, HLA-B-5601, HLA-B-5602, HLA -B, leukocyte antigen class I-B, HLA-B35 antigen, HLA class I histocompatibility antigen, Cw-5 alpha chain, MHC HLA-B27d, HLA-B alpha chain, HLA-B alpha-chain, major histocompatability complex B antigen, MHC class I antigen SHCHA, MHC class I antigen B*35, HLA class I histocompatibility antigen, B alpha chain, MHC class I alpha chain, MHC class I antigen B*39, HLA-B-6701, HLA-B alpha chain (B*2706), HLA-B27, MHC class I antigen B*38, MHC class I antigen B*37, MHC classI antigen, HLA class I histocompatibility antigen, B-50 alpha chain, HLA locus, MHC class I antigen HLA-B alpha chain, MHC HLA-B39N, MHC class I anitgen, lymphocyte antigen
Source: HGNC:4932
Biotype: protein coding gene
Dmd
(Mus musculus)Gene
Name: dystrophin, muscular dystrophy
Synonyms: mdx, X-linked muscular dystrophy, Duchenne muscular dystrophy, Dp71, DNADMD1, pke, pyruvate kinase expression, Dp427, dys
Source: MGI:94909
Biotype: protein coding gene
Actb
(Mus musculus)Gene
Name: actin, beta
Synonyms: A-X actin-like protein, E430023M04Rik, RIKEN cDNA E430023M04 gene, Actx, melanoma X-actin, beta-actin
Source: MGI:87904
Biotype: protein coding gene
Adh1
(Mus musculus)Gene
Name: alcohol dehydrogenase 1 (class I)
Synonyms: Adh-1e, ADH-AA, Adh, alcohol dehydrogenase 1 temporal, liver, Adh-1, expressed sequence AI194826, alcohol dehydrogenase 1, electrophoretic, Adh1-t, alcohol dehydrogenase 1 complex, AI194826, class I alcohol dehydrogenase, Adh1a, Adh-1t, Adh1tl, Adh-1-t, Adh1-e, alcohol dehydrogenase 1 temporal
Source: MGI:87921
Biotype: protein coding gene
Mx1
(Mus musculus)Gene
Name: MX dynamin-like GTPase 1
Synonyms: myxovirus (influenza) resistance 1 polypeptide, expressed sequence AI893580, Mx-1, Mx, AI893580
Source: MGI:97243
Biotype: polymorphic pseudogene
Adc
(Drosophila melanogaster)Gene
Name: Acidic amino acid decarboxylase
Synonyms: ADC, b, Dm-ADC, B, Glutamic acid decarboxylase 2, BG:DS00941.5, Oregon-R glutamate decarboxylase, black, Gad2, cysteine sulfinic acid decarboxylase, anon-34Db, Black, CG7811, DGad2, aspartate decarboxylase, GAD[[2]], cDNA 1, DmGad2, aspartate 1-decarboxylase, ADC/CSADC
Source: FB:FBgn0000153
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: mechanistic target of rapamycin, rapamycin target protein 1, rapamycin and FKBP12 target 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FKBP12-rapamycin complex-associated protein 1, FRAP2, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, SKS, FRAP, serine/threonine-protein kinase mTOR, RAPT1, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
PAH
(Homo sapiens)Gene
Name: phenylalanine hydroxylase
Synonyms: phenylalanine 4-monooxygenase, phenylalanine-4-hydroxylase, PKU1, phe-4-monooxygenase, PH, PKU
Source: HGNC:8582
Biotype: protein coding gene
MTHFR
(Homo sapiens)Gene
Name: methylenetetrahydrofolate reductase
Synonyms: methylenetetrahydrofolate reductase (NAD(P)H), methylenetetrahydrofolate reductase (NADPH), 5,10-methylenetetrahydrofolate reductase (NADPH)
Source: HGNC:7436
Biotype: protein coding gene
Apex2
(Mus musculus)Gene
Name: apurinic/apyrimidinic endonuclease 2
Synonyms: C430040P13Rik, RIKEN cDNA C430040P13 gene, Ape2
Source: MGI:1924872
Biotype: protein coding gene
RECQL
(Homo sapiens)Gene
Name: RecQ like helicase
Synonyms: RecQ protein-like (DNA helicase Q1-like), RecQ1, recQ protein-like 1, DNA helicase, RecQ-like type 1, ATP-dependent DNA helicase Q1, DNA helicase Q1-like, RECON, DNA 3'-5' helicase Q1, DNA-dependent ATPase Q1, RecQ helicase-like, RECQL1
Source: HGNC:9948
Biotype: protein coding gene
DNAJA2
(Homo sapiens)Gene
Name: DnaJ heat shock protein family (Hsp40) member A2
Synonyms: cell cycle progression restoration gene 3 protein, dnaJ homolog subfamily A member 2, HIRA-interacting protein 4, DJ3, HIRA interacting protein 4, CPR3, DNAJ, DNJ3, HIRIP4, DJA2, renal carcinoma antigen NY-REN-14, RDJ2, DnaJ (Hsp40) homolog, subfamily A, member 2, cell cycle progression 3 protein, PRO3015
Source: HGNC:14884
Biotype: protein coding gene
myo-3
(Caenorhabditis elegans)Gene
Name: MYOsin heavy chain structural genes 3
Synonyms: CELE_K12F2.1, K12F2.1, sup-3
Source: WB:WBGene00003515
Biotype: protein coding gene
Acly
(Rattus norvegicus)Gene
Name: ATP citrate lyase
Synonyms: ATP-citrate synthase, MGC124629, citrate cleavage enzyme, Clatp, ACL, ATP-citrate (pro-S-)-lyase
Source: RGD:2018
Biotype: protein coding gene
SGS1
(Saccharomyces cerevisiae)Gene
Name: Slow Growth Suppressor
Synonyms: YMR190C
Source: SGD:S000004802
Biotype: protein coding gene
SIS2
(Saccharomyces cerevisiae)Gene
Name: SIt4 Suppressor
Synonyms: HAL3, YKR072C
Source: SGD:S000001780
Biotype: protein coding gene
Hprt1
(Mus musculus)Gene
Name: hypoxanthine phosphoribosyltransferase 1
Synonyms: Hgprtase, expressed sequence C81579, hypoxanthine guanine phosphoribosyl transferase, Hprt, C81579, hypoxanthine guanine phosphoribosyl transferase 1
Source: MGI:96217
Biotype: protein coding gene
let-23
(Caenorhabditis elegans)Gene
Name: LEThal 23
Synonyms: CELE_ZK1067.1, ZK1067.1, kin-7
Source: WB:WBGene00002299
Biotype: protein coding gene
shha
(Danio rerio)Gene
Name: sonic hedgehog signaling molecule a
Synonyms: shh, vertebrate hedgehog homolog, sonic you, sonic-you, vhh1, fc83d08, syu, wu:fc83d08
Source: ZFIN:ZDB-GENE-980526-166
Biotype: protein coding gene
ACE2
(Saccharomyces cerevisiae)Gene
Name: Activator of CUP1 Expression
Synonyms: YLR131C
Source: SGD:S000004121
Biotype: protein coding gene
SOD1
(Saccharomyces cerevisiae)Gene
Name: SuperOxide Dismutase
Synonyms: YJR104C, CRS4
Source: SGD:S000003865
Biotype: protein coding gene
Tyr
(Mus musculus)Gene
Name: tyrosinase
Synonyms: skin/coat color 35, Oca1, c, albino, skc35
Source: MGI:98880
Biotype: protein coding gene
N
(Drosophila melanogaster)Gene
Name: Notch
Synonyms: 16-178, 16-55, RICN, Abruptex, Chp, Co, EG:163A10.2, Confluens, split, anon-EST:Liang-1.12, Ax, dNotch, Nicd, Chopped, Notch, NOTCH, strawberry, clone 1.12, co, spl, shd, 1.1, nd, l(1)3Cb, NICD, CG3936, notchoid, n[fah], notch, fa, NECD, CT13012, EG:140G11.1, facet, l(1)Ax, l(1)N, swb
Source: FB:FBgn0004647
Biotype: protein coding gene
Rag2
(Mus musculus)Gene
Name: recombination activating gene 2
Synonyms: Rag-2
Source: MGI:97849
Biotype: protein coding gene
ARO9
(Saccharomyces cerevisiae)Gene
Name: AROmatic amino acid requiring
Synonyms: YHR137W
Source: SGD:S000001179
Biotype: protein coding gene
PCK1
(Saccharomyces cerevisiae)Gene
Name: Phosphoenolpyruvate CarboxyKinase
Synonyms: JPM2, YKR097W, PPC1
Source: SGD:S000001805
Biotype: protein coding gene
GAL4
(Saccharomyces cerevisiae)Gene
Name: GALactose metabolism
Synonyms: YPL248C, GAL81
Source: SGD:S000006169
Biotype: protein coding gene
Mmp2
(Mus musculus)Gene
Name: matrix metallopeptidase 2
Synonyms: GelA, MMP-2, collagenase IVA, basement membrane, 72 kDa, gelatinase A, Clg4a, 72kDa type IV collagenase, 72kDa gelatinase
Source: MGI:97009
Biotype: protein coding gene
MARCHF6
(Homo sapiens)Gene
Name: membrane associated ring-CH-type finger 6
Synonyms: membrane associated ring finger 6, TEB4, membrane-associated RING-CH protein VI, E3 ubiquitin-protein ligase MARCHF6, RING-type E3 ubiquitin transferase MARCH6, MARCH6, membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase, membrane-associated RING finger protein 6, MARCH-VI, FCMTE3, RING-type E3 ubiquitin transferase MARCHF6, KIAA0597, DOA10, E3 ubiquitin-protein ligase MARCH6, membrane-associated RING-CH finger protein 6, protein TEB-4, RING finger protein 176, FAME3, doa10 homolog, RNF176
Source: HGNC:30550
Biotype: protein coding gene
Cyp21a1
(Mus musculus)Gene
Name: cytochrome P450, family 21, subfamily a, polypeptide 1
Synonyms: 21-OH, 21OHA, Cyp21, Oh21-1, steroid hydroxylase A, 21-hydroxylase, 21OH
Source: MGI:88591
Biotype: protein coding gene
Brca1
(Mus musculus)Gene
Name: breast cancer 1, early onset
Synonyms: BRCA-1
Source: MGI:104537
Biotype: protein coding gene
CLPB
(Homo sapiens)Gene
Name: ClpB family mitochondrial disaggregase
Synonyms: MGCA7, SKD3, ANKCLB, ankyrin-repeat containing bacterial clp fusion, ClpB homolog, mitochondrial AAA ATPase chaperonin, caseinolytic peptidase B protein homolog, testicular secretory protein Li 11, MEGCANN, MGCA7A, suppressor of potassium transport defect 3, ANKCLP, mitochondrial disaggregase, FLJ13152, caseinolytic mitochondrial matrix peptidase chaperone subunit B, HSP78, ClpB caseinolytic peptidase B homolog, SCN9
Source: HGNC:30664
Biotype: protein coding gene
CCR4
(Saccharomyces cerevisiae)Gene
Name: Carbon Catabolite Repression
Synonyms: YAL021C, FUN27, NUT21
Source: SGD:S000000019
Biotype: protein coding gene
ACTB
(Homo sapiens)Gene
Name: actin beta
Synonyms: actin, cytoplasmic 1, DDS1, beta cytoskeletal actin, actin, beta, CSMH, PS1TP5BP1, BNS, PS1TP5-binding protein 1, BKRNS, I(2)-actin, BRWS1, THC8
Source: HGNC:132
Biotype: protein coding gene
WDR45
(Homo sapiens)Gene
Name: WD repeat domain 45
Synonyms: WD repeat domain, X-linked 1, neurodegeneration with brain iron accumulation 5, WD repeat-containing protein 45, neurodegeneration with brain iron accumulation 4, NBIA4, NBIA5, JM5, WDRX1, WIPI4, WD45 repeat protein interacting with phosphoinositides 4, WD repeat domain phosphoinositide-interacting protein 4, WIPI-4
Source: HGNC:28912
Biotype: protein coding gene
plk-1
(Caenorhabditis elegans)Gene
Name: POLO Kinase 1
Synonyms: CELE_C14B9.4, C14B9.4, plc1
Source: WB:WBGene00004042
Biotype: protein coding gene