Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: microtubule cytoskeleton organization
Pten
(Mus musculus)Gene
Name: phosphatase and tensin homolog
Synonyms: B430203M17Rik, RIKEN cDNA B430203M17 gene, expressed sequence AI463227, RIKEN cDNA 2310035O07 gene, TEP1, Mmac, A130070J02Rik, MMAC1, AI463227, 2310035O07Rik, RIKEN cDNA A130070J02 gene
Source: MGI:109583
Biotype: protein coding gene
BRCA1
(Homo sapiens)Gene
Name: BRCA1 DNA repair associated
Synonyms: RNF53, early onset breast cancer 1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast cancer 1, BRCC1, BRCA1, DNA repair associated, RING finger protein 53, breast and ovarian cancer susceptibility protein 1, BRCA1/BRCA2-containing complex, subunit 1, breast cancer 1, early onset, IRIS, Fanconi anemia, complementation group S, breast cancer type 1 susceptibility protein, BRCAI, PNCA4, PSCP, truncated BRCA1, BROVCA1, protein phosphatase 1, regulatory subunit 53, breast cancer 1, PPP1R53, FANCS
Source: HGNC:1100
Biotype: protein coding gene
FLNA
(Homo sapiens)Gene
Name: filamin A
Synonyms: OPD, FLN-A, filamin-1, FLN1, FLN, XMVD, filamin A, alpha, XLVD, actin binding protein 280, FG syndrome 2, alpha filamin, MNS, filamin 1, DKFZp434P031, FMD, CSBS, FGS2, endothelial actin-binding protein, non-muscle filamin, OPD2, OPD1, NHBP, alpha-filamin, FLJ43642, filamin-A, ABPX, ABP-280, CVD1
Source: HGNC:3754
Biotype: protein coding gene
Pax6
(Mus musculus)Gene
Name: paired box 6
Synonyms: 1500038E17Rik, AEY11, RIKEN cDNA 1500038E17 gene, Pax-6, Sey, gsf abnormal eyes 11, Dey, Dickie's small eye, Gsfaey11, small eye
Source: MGI:97490
Biotype: protein coding gene
htt
(Drosophila melanogaster)Gene
Name: huntingtin
Synonyms: Huntingtin, CG9995, Htt, HTT, dHtt, dhtt, HD, DmHtt
Source: FB:FBgn0027655
Biotype: protein coding gene
CDC28
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: YBR160W, SRM5, HSL5, CDK1
Source: SGD:S000000364
Biotype: protein coding gene
BRCA2
(Homo sapiens)Gene
Name: BRCA2 DNA repair associated
Synonyms: truncated breast and ovarian cancer susceptibility protein 2, DNA repair-associated BRCA2, FAD1, truncated DNA repair-associated BRCA2, BRCC2, GLM3, BRCA2, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 2, breast cancer type 2 susceptibility protein, breast cancer 2, early onset, breast cancer 2 tumor suppressor, breast and ovarian cancer susceptibility gene, early onset, PNCA2, truncated BRCA2 DNA repair associated, fanconi anemia group D1 protein, truncated breast cancer 2, FAD, mutant BRCA2, breast cancer susceptibility protein BRCA2, FANCB, FANCD, breast and ovarian cancer susceptibility protein 2, mutant DNA repair-associated protein 2, FANCD1, BROVCA2, XRCC11, breast cancer 2, FACD
Source: HGNC:1101
Biotype: protein coding gene
POC1A
(Homo sapiens)Gene
Name: POC1 centriolar protein A
Synonyms: WD repeat-containing protein 51A, PIX2, proteome of centriole protein 1A, WD repeat domain 51A, MGC131902, WDR51A, POC1 centriolar protein homolog A, SOFT, DKFZp434C245
Source: HGNC:24488
Biotype: protein coding gene
PTEN
(Homo sapiens)Gene
Name: phosphatase and tensin homolog
Synonyms: MHAM, DEC, PTENepsilon, 10q23del, phosphatase and tensin-like protein, PTEN1, mitochondrial PTENalpha, GLM2, PTEN variant PTEN-K267Rfs*9, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, CWS1, mutated in multiple advanced cancers 1, MMAC1, PTEN variant PTEN-L247*, PTEN variant PTEN-R234Afs*11, mitochondrial phosphatase and tensin protein alpha, TEP1, PTENgama, inositol polyphosphate 3-phosphatase, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, BZS, PTENbeta, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MGC11227
Source: HGNC:9588
Biotype: protein coding gene
HTT
(Homo sapiens)Gene
Name: huntingtin
Synonyms: LOMARS, huntington disease protein, HD, IT15, huntington disease gene homolog
Source: HGNC:4851
Biotype: protein coding gene
PAX6
(Homo sapiens)Gene
Name: paired box 6
Synonyms: paired box 6 PAX6A-ASdel6-AS7 isoform, paired box homeotic gene-6, AN1, AN2, paired box 6 PAX6B-ASdel6 isoform, AN, paired box 6 PAX6A-del6 isoform, D11S812E, paired box protein Pax-6, MGDA, Aniridia 1, Aniridia 2, FVH1, paired box 6 PAX6-12a isoform, aniridia type II protein, oculorhombin, MGC17209, paired box 6 PAX6D isoform, ASGD5, WAGR, paired box 6 PAX6A-ASdel6 isoform, alternative protein PAX6
Source: HGNC:8620
Biotype: protein coding gene
Gapdh
(Mus musculus)Gene
Name: glyceraldehyde-3-phosphate dehydrogenase
Synonyms: cDNA sequence AK190093, BARS-38, AK190093, Gapd
Source: MGI:95640
Biotype: protein coding gene
Flna
(Mus musculus)Gene
Name: filamin, alpha
Synonyms: dilated pupils 2, filamin 1, filamin-1, Dilp2, actin-binding protein 280, Fln1, GENA 379, RIKEN cDNA F730004A14 gene, F730004A14Rik, ABP-280, RGD1560614
Source: MGI:95556
Biotype: protein coding gene
Htt
(Mus musculus)Gene
Name: huntingtin
Synonyms: C430023I11Rik, Huntington disease (human), expressed sequence AI256365, Huntington disease gene homolog, RIKEN cDNA C430023I11 gene, htt, Hd, HD, IT15, Hdh, AI256365
Source: MGI:96067
Biotype: protein coding gene
BNI1
(Saccharomyces cerevisiae)Gene
Name: Bud Neck Involved
Synonyms: SHE5, YNL271C, PPF3
Source: SGD:S000005215
Biotype: protein coding gene
VCP
(Homo sapiens)Gene
Name: valosin containing protein
Synonyms: epididymis secretory protein Li 70, IBMPFD, valosin-containing protein, HEL-S-70, MGC148092, CMT2Y, TERA, FTDALS6, transitional endoplasmic reticulum ATPase, yeast Cdc48p homolog, p97, 15S Mg(2+)-ATPase p97 subunit, HEL-220, MGC8560, TER ATPase, CDC48, MGC131997, ALS14, IBMPFD1, epididymis luminal protein 220
Source: HGNC:12666
Biotype: protein coding gene
Apc
(Mus musculus)Gene
Name: APC, WNT signaling pathway regulator
Synonyms: CC1, AI047805, expressed sequence AI047805, AU020952, adenomatosis polyposis coli, Min, expressed sequence AU020952, RATAPC, multiple intestinal neoplasia, expressed sequence AW124434, AW124434
Source: MGI:88039
Biotype: protein coding gene
CHEK2
(Homo sapiens)Gene
Name: checkpoint kinase 2
Synonyms: CDS1, HuCds1, PP1425, serine/threonine-protein kinase Chk2, checkpoint-like protein CHK2, TPDS4, CHK2 checkpoint homolog, cds1 homolog, RAD53, truncated checkpoint kinase 2, CHK2, LFS2, hCds1
Source: HGNC:16627
Biotype: protein coding gene
SNF1
(Saccharomyces cerevisiae)Gene
Name: Sucrose NonFermenting
Synonyms: CCR1, PAS14, CAT1, GLC2, HAF3, YDR477W
Source: SGD:S000002885
Biotype: protein coding gene
Cav1
(Mus musculus)Gene
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1, Cav
Source: MGI:102709
Biotype: protein coding gene
MAPT
(Homo sapiens)Gene
Name: microtubule associated protein tau
Synonyms: G protein beta1/gamma2 subunit-interacting factor 1, Tau-PHF6, microtubule-associated protein tau, isoform 4, PHF-tau, TAU, paired helical filament-tau, DDPAC, FLJ31424, PPP1R103, MAPTL, MSTD, Tau-derived paired helical filament hexapeptide, PPND, microtubule-associated protein tau, neurofibrillary tangle protein, FTDP-17, FTD1, MTBT1, MTBT2, MGC138549, tau-40
Source: HGNC:6893
Biotype: protein coding gene
Brca1
(Mus musculus)Gene
Name: breast cancer 1, early onset
Synonyms: BRCA-1
Source: MGI:104537
Biotype: protein coding gene
Brca2
(Mus musculus)Gene
Name: breast cancer 2, early onset
Synonyms: expressed sequence AW045498, AW045498, Fancd1, expressed sequence AI256696, AI256696, RAB163
Source: MGI:109337
Biotype: protein coding gene
plk-1
(Caenorhabditis elegans)Gene
Name: POLO Kinase 1
Synonyms: CELE_C14B9.4, C14B9.4, plc1
Source: WB:WBGene00004042
Biotype: protein coding gene
SMN1
(Homo sapiens)Gene
Name: survival of motor neuron 1, telomeric
Synonyms: BCD541, T-BCD541, survival of motor neuron 1 isoform D2A2B3457, GEMIN1, SMNT, SMA3, SMA4, SMA1, SMA2, survival of motor neuron 1 isoform D347, survival of motor neuron 1 isoform D345, survival of motor neuron 1 isoform D2A2B345, SMN2, component of gems 1, survival of motor neuron 1 isoform D2B3457, SMA@, TDRD16A, SMA, gemin 1, survival of motor neuron 1 isoform D2A3457, spinal muscular atrophy (Werdnig-Hoffmann disease, Kugelberg-Welander disease), gemin-1, SMN, tudor domain containing 16A, survival motor neuron protein, survival of motor neuron 1 isoform D3457, survival motor neuron 1 protein
Source: HGNC:11117
Biotype: protein coding gene
Ctnnb1
(Mus musculus)Gene
Name: catenin beta 1
Synonyms: beta-catenin, beta catenin, Catnb, batface, catenin beta, catenin (cadherin associated protein), beta 1, Bfc
Source: MGI:88276
Biotype: protein coding gene
APC
(Homo sapiens)Gene
Name: APC regulator of WNT signaling pathway
Synonyms: adenomatosis polyposis coli, PPP1R46, DP3, adenomatous polyposis coli protein, DP2, protein phosphatase 1, regulatory subunit 46, GS, DP2.5, deleted in polyposis 2.5, WNT signaling pathway regulator, truncated adenomatosis polyposis coli, BTPS2, adenomatous polyposis coli, DESMD, adenomatous polyposis coli (APC), adenomatosis polyposis coli tumor suppressor, APC, WNT signaling pathway regulator
Source: HGNC:583
Biotype: protein coding gene
Brca1
(Rattus norvegicus)Gene
Name: BRCA1, DNA repair associated
Synonyms: BRCA-1, breast cancer 1, early onset, breast cancer type 1 susceptibility protein homolog, breast cancer 1, RING-type E3 ubiquitin transferase BRCA1
Source: RGD:2218
Biotype: protein coding gene
LMNA
(Homo sapiens)Gene
Name: lamin A/C
Synonyms: LMNL1, FPL, 70 kDa lamin, LMN1, IDC, progeria 1 (Hutchinson-Gilford type), FPLD2, CMT2B1, mandibuloacral dysplasia type A, LMNC, LFP, CMD1A, PRO1, lamin, FPLD, HGPS, progerin, lamin A/C-like 1, lamin a, cardiomyopathy, dilated 1A (autosomal dominant), lamin-A/C, prelamin-A/C, MADA, EMD2, lamin C, LDP1, renal carcinoma antigen NY-REN-32, CDDC, LGMD1B, CDCD1
Source: HGNC:6636
Biotype: protein coding gene
CTNNB1
(Homo sapiens)Gene
Name: catenin beta 1
Synonyms: beta-catenin, catenin (cadherin-associated protein), beta 1, MRD19, EVR7, catenin (cadherin-associated protein), beta 1, 88kDa, DKFZp686D02253, CTNNB, armadillo, FLJ37923, catenin beta-1, NEDSDV, FLJ25606
Source: HGNC:2514
Biotype: protein coding gene
CDC14
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: YFR028C, OAF3
Source: SGD:S000001924
Biotype: protein coding gene
SRGAP2
(Homo sapiens)Gene
Name: SLIT-ROBO Rho GTPase activating protein 2
Synonyms: FNBP2, formin-binding protein 2, KIAA0456, srGAP3, SLIT-ROBO GAP2, formin binding protein 2, rho GTPase-activating protein 34, SLIT-ROBO Rho GTPase-activating protein 2, RP11-312O7.2, SRGAP2A, ARHGAP34
Source: HGNC:19751
Biotype: protein coding gene
CDC15
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: RLT1, LYT1, YAR019C
Source: SGD:S000000072
Biotype: protein coding gene
CDK1
(Homo sapiens)Gene
Name: cyclin dependent kinase 1
Synonyms: cell division cycle 2 homolog a (s. pombe), cell division control protein 2 homolog, cell division cycle 2, G1 to S and G2 to M, P34CDC2, cell cycle controller CDC2, MGC111195, DKFZp686L20222, cell division protein kinase 1, cyclin-dependent kinase 1, p34 protein kinase, CDC28A, CDC2
Source: HGNC:1722
Biotype: protein coding gene
Dag1
(Mus musculus)Gene
Name: dystroglycan 1
Synonyms: DNA segment, Chr 9, Wayne State University 13, expressed, DG, alpha-dystroglycan, beta-dystroglycan, D9Wsu13e, dystrophin associated glycoprotein 1
Source: MGI:101864
Biotype: protein coding gene
asp
(Drosophila melanogaster)Gene
Name: abnormal spindle
Synonyms: anon-96Aa, CG6875, anon-WO0118547.279, Abnormal spindles, abnormal spindle protein, Abnormal spindle, Abnormal spindle protein, abnormal spindles, Dm Asp, ASP, Asp
Source: FB:FBgn0000140
Biotype: protein coding gene
Tubb2b
(Mus musculus)Gene
Name: tubulin, beta 2B class IIB
Synonyms: brdp, Tubb2, RGD1309427, RIKEN cDNA 2410129E14 gene, 2410129E14Rik, brain dimple
Source: MGI:1920960
Biotype: protein coding gene
BMERB1
(Homo sapiens)Gene
Name: bMERB domain containing 1
Synonyms: uncharacterized protein C16orf45, FLJ32618, chromosome 16 open reading frame 45, hypothetical protein LOC89927, MINP, bMERB domain-containing protein 1, C16orf45
Source: HGNC:19213
Biotype: protein coding gene
CDC48
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: YDL126C
Source: SGD:S000002284
Biotype: protein coding gene
Wdr47
(Mus musculus)Gene
Name: WD repeat domain 47
Synonyms: AA552998, 1810073M12Rik, expressed sequence AA552998, RGD1309181, RIKEN cDNA 1810073M12 gene, mKIAA0893, nemitin
Source: MGI:2139593
Biotype: protein coding gene
Sac1
(Drosophila melanogaster)Gene
Name: Sac1 phosphatase
Synonyms: l(3)2107, impatent, CG9128, dsac1, suppressor of actin-1, sac1, Sac1
Source: FB:FBgn0283500
Biotype: protein coding gene
Ulk4
(Mus musculus)Gene
Name: unc-51-like kinase 4
Synonyms: RIKEN cDNA 4932415A06 gene, 4932415A06Rik, RGD1565726
Source: MGI:1921622
Biotype: protein coding gene
Itgb1
(Mus musculus)Gene
Name: integrin beta 1 (fibronectin receptor beta)
Synonyms: Gm9863, fibronectin receptor beta (integrin), expressed sequence AA960159, AA409975, 4633401G24Rik, expressed sequence AA409975, beta1 integrin, ENSMUSG00000051907, RIKEN cDNA 4633401G24 gene, AA960159, CD29, Fnrb, predicted gene 9863, predicted gene, ENSMUSG00000051907
Source: MGI:96610
Biotype: protein coding gene
Uxt
(Mus musculus)Gene
Name: ubiquitously expressed prefoldin like chaperone
Synonyms: RIKEN cDNA 0910002B17 gene, 0910002B17Rik
Source: MGI:1277988
Biotype: protein coding gene
Cfl1
(Mus musculus)Gene
Name: cofilin 1, non-muscle
Synonyms: cofilin, expressed sequence AA959946, AA959946, Cof, n-cofilin
Source: MGI:101757
Biotype: protein coding gene
Ttll9
(Mus musculus)Gene
Name: tubulin tyrosine ligase-like family, member 9
Synonyms: RIKEN cDNA 1700016F23 gene, expressed sequence AW046572, RIKEN cDNA 4930509O20 gene, 1700016F23Rik, AW046572, 4930509O20Rik
Source: MGI:1913589
Biotype: protein coding gene
PLK1
(Homo sapiens)Gene
Name: polo like kinase 1
Synonyms: polo-like kinase 1, polo like kinase, cell cycle regulated protein kinase, serine/threonine-protein kinase 13, serine/threonine-protein kinase PLK1, PLK-1, STPK13, polo (Drosophia)-like kinase, PLK
Source: HGNC:9077
Biotype: protein coding gene
DOCK7
(Homo sapiens)Gene
Name: dedicator of cytokinesis 7
Synonyms: dedicator of cytokinesis protein 7, ZIR2, EIEE23, KIAA1771, DEE23
Source: HGNC:19190
Biotype: protein coding gene
CDC5
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: MSD2, PKX2, YMR001C
Source: SGD:S000004603
Biotype: protein coding gene
MYO2
(Saccharomyces cerevisiae)Gene
Name: MYOsin
Synonyms: CDC66, YOR326W
Source: SGD:S000005853
Biotype: protein coding gene