Version: 8.0.0Date: Tue Jan 28 2025
Gene Diseases: disease of mental health
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Pten
(Mus musculus)Gene
Name: phosphatase and tensin homolog
Synonyms: B430203M17Rik, RIKEN cDNA B430203M17 gene, expressed sequence AI463227, RIKEN cDNA 2310035O07 gene, TEP1, Mmac, A130070J02Rik, MMAC1, AI463227, 2310035O07Rik, RIKEN cDNA A130070J02 gene
Source: MGI:109583
Biotype: protein coding gene
ACT1
(Saccharomyces cerevisiae)Gene
Name: ACTin
Synonyms: ABY1, END7, YFL039C
Source: SGD:S000001855
Biotype: protein coding gene
Pax6
(Mus musculus)Gene
Name: paired box 6
Synonyms: 1500038E17Rik, AEY11, RIKEN cDNA 1500038E17 gene, Pax-6, Sey, gsf abnormal eyes 11, Dey, Dickie's small eye, Gsfaey11, small eye
Source: MGI:97490
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
daf-2
(Caenorhabditis elegans)Gene
Name: abnormal DAuer Formation 2
Synonyms: Y55D5A.5, CELE_Y55D5A.5
Source: WB:WBGene00000898
Biotype: protein coding gene
ss
(Drosophila melanogaster)Gene
Name: spineless
Synonyms: Ss, SS, ssa, Spineless, CG6993, aristapedia, dAHR, AhR, AHR, spineless-aristapedia
Source: FB:FBgn0003513
Biotype: protein coding gene
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide(1-42), beta-amyloid peptide, preA4, beta-amyloid peptide(1-40), cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, alpha-sAPP, AD1, alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), protease nexin-II, CTFgamma, amyloid beta A4 protein, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
PTEN
(Homo sapiens)Gene
Name: phosphatase and tensin homolog
Synonyms: MHAM, DEC, PTENepsilon, 10q23del, phosphatase and tensin-like protein, PTEN1, mitochondrial PTENalpha, GLM2, PTEN variant PTEN-K267Rfs*9, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, CWS1, mutated in multiple advanced cancers 1, MMAC1, PTEN variant PTEN-L247*, PTEN variant PTEN-R234Afs*11, mitochondrial phosphatase and tensin protein alpha, TEP1, PTENgama, inositol polyphosphate 3-phosphatase, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, BZS, PTENbeta, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MGC11227
Source: HGNC:9588
Biotype: protein coding gene
EGFR
(Homo sapiens)Gene
Name: epidermal growth factor receptor
Synonyms: PIG61, NNCIS, receptor tyrosine-protein kinase erbB-1, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), erythroblastic leukemia viral (v-erb-b) oncogene homolog, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, NISBD2, HER1
Source: HGNC:3236
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, MGC1571, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2
Source: HGNC:613
Biotype: protein coding gene
PAX6
(Homo sapiens)Gene
Name: paired box 6
Synonyms: paired box 6 PAX6A-ASdel6-AS7 isoform, paired box homeotic gene-6, AN1, AN2, paired box 6 PAX6B-ASdel6 isoform, AN, paired box 6 PAX6A-del6 isoform, D11S812E, paired box protein Pax-6, MGDA, Aniridia 1, Aniridia 2, FVH1, paired box 6 PAX6-12a isoform, aniridia type II protein, oculorhombin, MGC17209, paired box 6 PAX6D isoform, ASGD5, WAGR, paired box 6 PAX6A-ASdel6 isoform, alternative protein PAX6
Source: HGNC:8620
Biotype: protein coding gene
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
SYNGAP1
(Homo sapiens)Gene
Name: synaptic Ras GTPase activating protein 1
Synonyms: SYNGAP, Ras/Rap GTPase-activating protein 1, synaptic Ras GTPase activating protein, 135kDa, MRD5, RASA1, ras/Rap GTPase-activating protein SynGAP, RASA5, ras GTPase-activating protein SynGAP, synaptic Ras GTPase-activating protein 1, synaptic Ras GTPase activating protein 1 homolog, KIAA1938, DKFZp761G1421, neuronal RasGAP
Source: HGNC:11497
Biotype: protein coding gene
Tardbp
(Mus musculus)Gene
Name: TAR DNA binding protein
Synonyms: Tdp43, 1190002A23Rik, expressed sequence C85084, TDP-43, Tdp-43, RIKEN cDNA 1190002A23 gene, C85084
Source: MGI:2387629
Biotype: protein coding gene
KRAS
(Homo sapiens)Gene
Name: KRAS proto-oncogene, GTPase
Synonyms: KI-RAS, RALD, NS, c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, PR310 c-K-ras oncogene, KRAS-ENOPH fusion, K-RAS2B, GTPase KRas, K-RAS2A, NS3, K-RAS4B, K-RAS4A, c-Kirsten-ras protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, Kirsten rat sarcoma viral proto-oncogene, c-Ki-ras, Kirsten rat sarcoma viral oncogene homolog, oncogene KRAS2, K-ras p21 protein, RASK2, CFC2, K-Ras, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, C-K-RAS, K-Ras 2, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, OES, cellular transforming proto-oncogene, KRAS2, 'C-K-RAS, proto-oncogene GTPase, transforming protein p21, KRAS1
Source: HGNC:6407
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
ebi
(Drosophila melanogaster)Gene
Name: ebi
Synonyms: FBXW4, beta transducin-like 1 protein, Enhancer on chromosome 2-complementation group 2g, Tbl1, CG4063, Tb11, E-2f, E-2g, Ebi, l(2)k16213
Source: FB:FBgn0263933
Biotype: protein coding gene
DMD
(Homo sapiens)Gene
Name: dystrophin
Synonyms: truncated dystrophin, DXS270, mutant dystrophin, dystrophin (muscular dystrophy, Duchenne and Becker types), DXS272, mental retardation, X-linked 85, DXS239, DXS206, MRX85, BMD, DXS142, DXS230, DXS164, DXS268, CMD3B, DXS269
Source: HGNC:2928
Biotype: protein coding gene
BCL2
(Homo sapiens)Gene
Name: BCL2 apoptosis regulator
Synonyms: Bcl-2, protein phosphatase 1, regulatory subunit 50, Bcl-2a, B-cell CLL/lymphoma 2, PPP1R50, Bcl-2ß, apoptosis regulator Bcl-2, b-cell leukemia/lymphoma 2, BCL2, apoptosis regulator
Source: HGNC:990
Biotype: protein coding gene
SIRT1
(Homo sapiens)Gene
Name: sirtuin 1
Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, regulatory protein SIR2 homolog 1, hSIRT1, hSIR2, sirtuin type 1, NAD-dependent deacetylase sirtuin-1
Source: HGNC:14929
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, Alzheimer disease amyloid beta protein, cerebrovascular amyloid peptide, protease nexin II, expressed sequence AL024401, AL024401, RIKEN cDNA E030013M08 gene, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
Dmd
(Mus musculus)Gene
Name: dystrophin, muscular dystrophy
Synonyms: mdx, X-linked muscular dystrophy, Duchenne muscular dystrophy, Dp71, DNADMD1, pke, pyruvate kinase expression, Dp427, dys
Source: MGI:94909
Biotype: protein coding gene
Adh1
(Mus musculus)Gene
Name: alcohol dehydrogenase 1 (class I)
Synonyms: Adh-1e, ADH-AA, Adh, alcohol dehydrogenase 1 temporal, liver, Adh-1, expressed sequence AI194826, alcohol dehydrogenase 1, electrophoretic, Adh1-t, alcohol dehydrogenase 1 complex, AI194826, class I alcohol dehydrogenase, Adh1a, Adh-1t, Adh1tl, Adh-1-t, Adh1-e, alcohol dehydrogenase 1 temporal
Source: MGI:87921
Biotype: protein coding gene
SOD1
(Homo sapiens)Gene
Name: superoxide dismutase 1
Synonyms: Cu/Zn superoxide dismutase, ALS, SOD, superoxide dismutase [Cu-Zn], indophenoloxidase A, HEL-S-44, superoxide dismutase 1, soluble, epididymis secretory protein Li 44, SOD, soluble, STAHP, hSod1, superoxide dismutase, cystolic, superoxide dismutase, ALS1, IPOA, homodimer
Source: HGNC:11179
Biotype: protein coding gene
para
(Drosophila melanogaster)Gene
Name: paralytic
Synonyms: Shudderer, bss, bangsenseless, DmNa[[v]]1, l(1)ESHS48, Paralytic, DmNav, bang senseless, Out cold, olfD, smell-blind, smellblind, Scn1alpha, bas, parabss, DmNav1, voltage-sensitive sodium channel, DmNa, CG9907, para13-5, DmNa[[v]], lincRNA.S9469, par, Shu, sbl-1, VSSC, Para, Nav1, Ocd, Out-cold, paralyzed, voltage gated sodium ion channel, l(1)14Da, sbl, DmNa[[V]], bang-senseless, bang sensitive
Source: FB:FBgn0285944
Biotype: protein coding gene
PAH
(Homo sapiens)Gene
Name: phenylalanine hydroxylase
Synonyms: phenylalanine 4-monooxygenase, phenylalanine-4-hydroxylase, PKU1, phe-4-monooxygenase, PH, PKU
Source: HGNC:8582
Biotype: protein coding gene
pax6a
(Danio rerio)Gene
Name: paired box 6a
Synonyms: paxzfa, fc20e07, Pax6.1, pax-a, wu:fc20e07, pax[zf-a], zfpax-6b, zfpax-6a, etID309716.25, pax6, cb280
Source: ZFIN:ZDB-GENE-990415-200
Biotype: protein coding gene
MTHFR
(Homo sapiens)Gene
Name: methylenetetrahydrofolate reductase
Synonyms: methylenetetrahydrofolate reductase (NAD(P)H), methylenetetrahydrofolate reductase (NADPH), 5,10-methylenetetrahydrofolate reductase (NADPH)
Source: HGNC:7436
Biotype: protein coding gene
MIP1
(Saccharomyces cerevisiae)Gene
Name: MItochondrial DNA Polymerase
Synonyms: YOR330C
Source: SGD:S000005857
Biotype: protein coding gene
daf-16
(Caenorhabditis elegans)Gene
Name: abnormal DAuer Formation 16
Synonyms: daf-17, R13H8.1, CELE_R13H8.1
Source: WB:WBGene00000912
Biotype: protein coding gene
Ptgs2
(Mus musculus)Gene
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX-2, Cox-2, PHS II, Cox2, Pghs2, cyclooxygenase-2, prostaglandin G/H synthase, PHS-2, COX2, PGHS-2, cyclooxygenase 2, Tis10
Source: MGI:97798
Biotype: protein coding gene
let-23
(Caenorhabditis elegans)Gene
Name: LEThal 23
Synonyms: CELE_ZK1067.1, ZK1067.1, kin-7
Source: WB:WBGene00002299
Biotype: protein coding gene
H2-Aa
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen A, alpha
Synonyms: BA1, I-Aalpha, histocompatibility 2, class II antigen A alpha, H-2Aa, A alpha, Ia1, Aalpha, I region-associated antigen 1, Ia-1
Source: MGI:95895
Biotype: protein coding gene
shha
(Danio rerio)Gene
Name: sonic hedgehog signaling molecule a
Synonyms: shh, vertebrate hedgehog homolog, sonic you, sonic-you, vhh1, fc83d08, syu, wu:fc83d08
Source: ZFIN:ZDB-GENE-980526-166
Biotype: protein coding gene
Nlg2
(Drosophila melanogaster)Gene
Name: Neuroligin 2
Synonyms: neuroligin 2, Nlg-2, nl2, CG13772, dnlg2, Neuroligin, nlg2, Dnlg2, DNlg2, neuroligin, dnl2
Source: FB:FBgn0031866
Biotype: protein coding gene
Slc6a4
(Mus musculus)Gene
Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Synonyms: 5-HTT, 5-hydroxytryptamine (serotonin) transporter, SERT, Sert, Htt, AI323329, expressed sequence AI323329
Source: MGI:96285
Biotype: protein coding gene
Mmp2
(Mus musculus)Gene
Name: matrix metallopeptidase 2
Synonyms: GelA, MMP-2, collagenase IVA, basement membrane, 72 kDa, gelatinase A, Clg4a, 72kDa type IV collagenase, 72kDa gelatinase
Source: MGI:97009
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: mechanistic target of rapamycin, rapamycin target protein 1, rapamycin and FKBP12 target 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FKBP12-rapamycin complex-associated protein 1, FRAP2, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, SKS, FRAP, serine/threonine-protein kinase mTOR, RAPT1, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
H2-Ab1
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen A, beta 1
Synonyms: Bb, expressed sequence AI845868, response to metastatic cancers 1, H-2Ab, RT1.B, H2-Ab, histocompatibility 2, class II antigen A, beta, IAb, Rmcs1, I-region-associated antigen 2, I-A, AI845868, A beta, Abeta, Ia2, I-Abeta, Ia-2
Source: MGI:103070
Biotype: protein coding gene
HLA-DRB1
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 1
Synonyms: MHC class II HLA-DRw10-beta, HLA-DRB1*, leucocyte antigen DRB1, DW2.2/DR2.2, FLJ76359, HLA-DR-beta 1, leucocyte antigen DR beta 1 chain, MHC class II antigen, major histocompatibility complex, class II, DR beta 1 precursor, DRw8, SS1, DR16, DR-8, MHC class II HLA-DR beta 1 chain, lymphocyte antigen DRB1, DRB1, DR-16, HLA class II histocompatibility antigen, DR-1 beta chain, DR1, MHC class II antigen HLA-DR13, DR5, FLJ75017, HLA class II antigen beta chain, DR8, DRw11, DRw10, MHC class II HLA-DR-beta cell surface glycoprotein, human leucocyte antigen DRB1, HLA-DR1B, HLA-DRB
Source: HGNC:4948
Biotype: protein coding gene
SOD1
(Saccharomyces cerevisiae)Gene
Name: SuperOxide Dismutase
Synonyms: YJR104C, CRS4
Source: SGD:S000003865
Biotype: protein coding gene
HRAS
(Homo sapiens)Gene
Name: HRas proto-oncogene, GTPase
Synonyms: HAMSV, Ras family small GTP binding protein H-Ras, H-RASIDX, GTPase KRas, RASH1, Harvey rat sarcoma viral oncoprotein, ha-Ras, transformation gene: oncogene HAMSV, GTP- and GDP-binding peptide B, c-Ki-ras, p19 H-RasIDX protein, H-Ras-1, Ha-Ras1 proto-oncoprotein, p21ras, C-H-RAS, N-RAS, c-has/bas p21 protein, HRAS1, RASK2, Harvey rat sarcoma viral oncogene homolog, GTPase HRas, CTLO, Ki-Ras, c-K-ras, K-RAS, c-ras-Ki-2 activated oncogene, C-BAS/HAS, K-Ras 2, KRAS, C-HA-RAS1, v-Ha-ras Harvey rat sarcoma viral oncogene homolog, KRAS2, transforming protein p21
Source: HGNC:5173
Biotype: protein coding gene
Prkn
(Mus musculus)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkinson disease (autosomal recessive, juvenile) 2, parkin, Park2, Parkin, Park
Source: MGI:1355296
Biotype: protein coding gene
N
(Drosophila melanogaster)Gene
Name: Notch
Synonyms: 16-178, 16-55, RICN, Abruptex, Chp, Co, EG:163A10.2, Confluens, split, anon-EST:Liang-1.12, Ax, dNotch, Nicd, Chopped, Notch, NOTCH, strawberry, clone 1.12, co, spl, shd, 1.1, nd, l(1)3Cb, NICD, CG3936, notchoid, n[fah], notch, fa, NECD, CT13012, EG:140G11.1, facet, l(1)Ax, l(1)N, swb
Source: FB:FBgn0004647
Biotype: protein coding gene
Bdnf
(Mus musculus)Gene
Name: brain derived neurotrophic factor
Synonyms: Not Available
Source: MGI:88145
Biotype: protein coding gene
FAA1
(Saccharomyces cerevisiae)Gene
Name: Fatty Acid Activation
Synonyms: YOR317W
Source: SGD:S000005844
Biotype: protein coding gene