Version: 8.0.0
Date: Tue Jan 28 2025
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117 results
Gene Molecular Function: metal ion binding Molecular Function: damaged DNA binding

BRCA1

(Homo sapiens)
Gene
Name: BRCA1 DNA repair associated
Synonyms: RNF53, early onset breast cancer 1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast cancer 1, BRCC1, BRCA1, DNA repair associated, RING finger protein 53, breast and ovarian cancer susceptibility protein 1, BRCA1/BRCA2-containing complex, subunit 1, breast cancer 1, early onset, IRIS, Fanconi anemia, complementation group S, breast cancer type 1 susceptibility protein, BRCAI, PNCA4, PSCP, truncated BRCA1, BROVCA1, protein phosphatase 1, regulatory subunit 53, breast cancer 1, PPP1R53, FANCS
Source: HGNC:1100
Biotype: protein coding gene

ERCC5

(Homo sapiens)
Gene
Name: ERCC excision repair 5, endonuclease
Synonyms: xeroderma pigmentosum, complementation group G, ERCC5-201, UVDR, ERCM2, xeroderma pigmentosum group G-complementing protein, XPG, COFS3, excision repair protein, excision repair cross-complementing rodent repair deficiency, complementation group 5, DNA repair protein complementing XP-G cells, excision repair cross-complementation group 5, XPG-complementing protein, DNA excision repair protein ERCC-5, XPGC, xeroderma pigmentosum complementation group G protein
Source: HGNC:3437
Biotype: protein coding gene

ERCC2

(Homo sapiens)
Gene
Name: ERCC excision repair 2, TFIIH core complex helicase subunit
Synonyms: general transcription and DNA repair factor IIH helicase subunit XPD, TTD, TFIIH basal transcription factor complex 80 kDa subunit, TTD1, TFIIH basal transcription factor complex helicase subunit, COFS2, DNA 5'-3' helicase XPD, XPD, EM9, excision repair cross-complementing rodent repair deficiency, complementation group 2, xeroderma pigmentosum complementary group D, xeroderma pigmentosum group D-complementing protein, BTF2 p80, basic transcription factor 2 80 kDa subunit, trichothiodystrophy, MGC102762, MGC126218, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex helicase XPB subunit, MGC126219, excision repair cross-complementation group 2, TFIIH basal transcription factor complex helicase XPD subunit, TFIIH subunit XPD, TFIIH, CXPD, TFIIH p80, TFIIH 80 kDa subunit, DNA excision repair protein ERCC-2
Source: HGNC:3434
Biotype: protein coding gene

Brca1

(Mus musculus)
Gene
Name: breast cancer 1, early onset
Synonyms: BRCA-1
Source: MGI:104537
Biotype: protein coding gene

XPA

(Homo sapiens)
Gene
Name: XPA, DNA damage recognition and repair factor
Synonyms: XPAC, RP11-244N9.4, xeroderma pigmentosum, complementation group A, XP1, excision repair-controlling, DNA repair protein complementing XP-A cells, xeroderma pigmentosum group A-complementing protein, mutant xeroderma pigmentosum complementation group A
Source: HGNC:12814
Biotype: protein coding gene

Brca1

(Rattus norvegicus)
Gene
Name: BRCA1, DNA repair associated
Synonyms: BRCA-1, breast cancer 1, early onset, breast cancer type 1 susceptibility protein homolog, breast cancer 1, RING-type E3 ubiquitin transferase BRCA1
Source: RGD:2218
Biotype: protein coding gene

APEX1

(Homo sapiens)
Gene
Name: apurinic/apyrimidinic endodeoxyribonuclease 1
Synonyms: DNA repair nuclease/redox regulator APEX1, redox factor-1, multifunctional DNA repair enzyme, deoxyribonuclease (apurinic or apyrimidinic), AP endonuclease 1, DNA-(apurinic or apyrimidinic site) lyase, APE1, APEN, DNA-(apurinic or apyrimidinic site) endonuclease, apurinic-apyrimidinic endonuclease 1, APX, apurinic/apyrimidinic exonuclease, AP lyase, AP endonuclease class I, APE, APEX nuclease (multifunctional DNA repair enzyme) 1, apurinic/apyrimidinic (abasic) endonuclease, REF1, HAP1, protein REF-1, APEX, redox factor 1
Source: HGNC:587
Biotype: protein coding gene

EP300

(Homo sapiens)
Gene
Name: E1A binding protein p300
Synonyms: p300, p300 HAT, MKHK2, KAT3B, histone butyryltransferase p300, histone acetyltransferase p300, E1A-binding protein, 300kD, RSTS2, E1A-associated protein p300, histone crotonyltransferase p300
Source: HGNC:3373
Biotype: protein coding gene

SIRT6

(Homo sapiens)
Gene
Name: sirtuin 6
Synonyms: NAD-dependent protein deacylase sirtuin-6, regulatory protein SIR2 homolog 6, sirtuin, NAD-dependent deacetylase sirtuin-6, SIR2-like protein 6, sirtuin type 6, hSIRT6, NAD-dependent protein deacetylase sirtuin-6, SIR2L6, sir2-related protein type 6
Source: HGNC:14934
Biotype: protein coding gene

Parp1

(Mus musculus)
Gene
Name: poly (ADP-ribose) polymerase family, member 1
Synonyms: poly (ADP-ribose) polymerase, Adprt1, Parp-1, expressed sequence AI893648, Adprp, PARP, ARTD1, sPARP-1, Adprt, AI893648, RIKEN cDNA 5830444G22 gene, parp-1, 5830444G22Rik, C80510, expressed sequence C80510, ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1
Source: MGI:1340806
Biotype: protein coding gene

WRN

(Homo sapiens)
Gene
Name: WRN RecQ like helicase
Synonyms: RECQ3, RECQL3, Werner syndrome RecQ like helicase, bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, Werner syndrome, RecQ helicase-like, recQ protein-like 2, exonuclease WRN, DNA helicase, RecQ-like type 3, DKFZp686C2056, RECQL2, Werner syndrome ATP-dependent helicase
Source: HGNC:12791
Biotype: protein coding gene

BLM

(Homo sapiens)
Gene
Name: BLM RecQ like helicase
Synonyms: MGRISCE1, Bloom syndrome RecQ like helicase, MGC131620, recQ-like DNA helicase BLM, Bloom syndrome, RecQ helicase-like, MGC126616, RECQL3, BS, RECQ2, Bloom syndrome protein, recQ protein-like 3, DNA helicase, RecQ-like type 2, MGC131618, DNA 3'-5' helicase BLM, RECQL2
Source: HGNC:1058
Biotype: protein coding gene

xpa

(Danio rerio)
Gene
Name: xeroderma pigmentosum, complementation group A
Synonyms: zgc:63640
Source: ZFIN:ZDB-GENE-040426-1205
Biotype: protein coding gene

MSH2

(Homo sapiens)
Gene
Name: mutS homolog 2
Synonyms: LCFS2, MSH-2, hMSH2, mismatch repair protein, HNPCC1, LOC124907764, DNA mismatch repair protein Msh2, FCC1, mutS protein homolog 2, LYNCH1, HNPCC, mutS homolog 2, colon cancer, nonpolyposis type 1, COCA1, MutS-like 2, MMRCS2, truncated MSH2, DNA mismatch repair protein Msh2 transcript, uncharacterized LOC124907764
Source: HGNC:7325
Biotype: protein coding gene

PARP1

(Homo sapiens)
Gene
Name: poly(ADP-ribose) polymerase 1
Synonyms: poly (ADP-ribose) polymerase 1, ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase), poly(ADP-ribose) polymerase, PARP, ARTD1, ADPRT 1, ADPRT1, PARP-1, NAD(+) ADP-ribosyltransferase 1, Poly-PARP, poly(ADP-ribosyl)transferase, pADPRT-1, DNA ADP-ribosyltransferase PARP1, poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase NAD(+), PARS, poly (ADP-ribose) polymerase family, member 1, PPOL, ADP-ribosyltransferase diphtheria toxin-like 1, poly[ADP-ribose] synthase 1, ADPRT, poly(ADP-ribose) synthetase
Source: HGNC:270
Biotype: protein coding gene

RBBP8

(Homo sapiens)
Gene
Name: RB binding protein 8, endonuclease
Synonyms: Seckel syndrome 2, RBBP-8, CTIP, CTBP-interacting protein, retinoblastoma-binding protein 8, retinoblastoma-interacting myosin-like, COM1, SCKL2, retinoblastoma binding protein 8, sporulation in the absence of SPO11 protein 2 homolog, JAWAD, RIM, DNA endonuclease RBBP8, SAE2, retinoblastoma-interacting protein and myosin-like, JWDS
Source: HGNC:9891
Biotype: protein coding gene

RAD18

(Homo sapiens)
Gene
Name: RAD18 E3 ubiquitin protein ligase
Synonyms: RAD18 homolog, hHR18, RAD18, E3 ubiquitin protein ligase, RING-type E3 ubiquitin transferase RAD18, postreplication repair protein RAD18, E3 ubiquitin-protein ligase RAD18, RAD18, S. cerevisiae, homolog, RING finger protein 73, hRAD18, RNF73, postreplication repair protein hRAD18p
Source: HGNC:18278
Biotype: protein coding gene

RAD3

(Saccharomyces cerevisiae)
Gene
Name: RADiation sensitive
Synonyms: REM1, YER171W
Source: SGD:S000000973
Biotype: protein coding gene

Ep300

(Mus musculus)
Gene
Name: E1A binding protein p300
Synonyms: p300, KAT3B
Source: MGI:1276116
Biotype: protein coding gene

FEN1

(Homo sapiens)
Gene
Name: flap structure-specific endonuclease 1
Synonyms: flap endonuclease 1, maturation factor 1, MF1, hFEN-1, FEN-1, maturation factor-1, RAD2, DNase IV
Source: HGNC:3650
Biotype: protein coding gene

CREBBP

(Homo sapiens)
Gene
Name: CREB binding protein
Synonyms: MKHK1, CBP, CREB-binding protein, KAT3A, histone lysine acetyltransferase CREBBP, protein-lysine acetyltransferase CREBBP, RSTS, RSTS1
Source: HGNC:2348
Biotype: protein coding gene

Recql4

(Mus musculus)
Gene
Name: RecQ protein-like 4
Synonyms: Not Available
Source: MGI:1931028
Biotype: protein coding gene

TP63

(Homo sapiens)
Gene
Name: tumor protein p63
Synonyms: chronic ulcerative stomatitis protein, OFC8, amplified in squamous cell carcinoma, keratinocyte transcription factor KET, p51, B(p51A), p73H, CUSP, TP53CP, EEC3, RHS, NBP, tumor protein p53-competing protein, tumor protein p53-like, tumor protein p63 deltaN isoform delta, AIS, SHFM4, transformation-related protein 63, p63, p40, B(p51B), TP73L, p73L, LMS, TP53L, p53CP, KET, tumor protein p73-like, tumor protein 63
Source: HGNC:15979
Biotype: protein coding gene

Apex1

(Mus musculus)
Gene
Name: apurinic/apyrimidinic endonuclease 1
Synonyms: REF-1, Ref-1, APE, HAP1, Apex
Source: MGI:88042
Biotype: protein coding gene

POLD1

(Homo sapiens)
Gene
Name: DNA polymerase delta 1, catalytic subunit
Synonyms: IMD120, polymerase (DNA) delta 1, catalytic subunit, DNA polymerase delta catalytic subunit, CRCS10, DNA-directed polymerase delta 1, polymerase (DNA directed), delta 1, catalytic subunit 125kDa, CDC2, POLD, DAN polymerase delta 1, catalytic subunit, dna polymerase delta, catalytic subunit, CDC2 homolog, MDPL, DNA polymerase subunit delta p125, 3'-5' exodeoxyribonuclease
Source: HGNC:9175
Biotype: protein coding gene

RECQL4

(Homo sapiens)
Gene
Name: RecQ like helicase 4
Synonyms: RECQ4, ATP-dependent DNA helicase Q4, DNA helicase, RecQ-like, type 4, DNA 3'-5' helicase RecQ4, DNA helicase, RecQ-like type 4, RecQ helicase-like 4, RecQ protein-like 4
Source: HGNC:9949
Biotype: protein coding gene

Crebbp

(Mus musculus)
Gene
Name: CREB binding protein
Synonyms: CBP, RTS, expressed sequence AW558298, KAT3A, RSTS, AW558298
Source: MGI:1098280
Biotype: protein coding gene

RAD14

(Saccharomyces cerevisiae)
Gene
Name: RADiation sensitive
Synonyms: YMR201C
Source: SGD:S000004814
Biotype: protein coding gene

MSH6

(Homo sapiens)
Gene
Name: mutS homolog 6
Synonyms: hMSH6, GTMBP, mutS protein homolog 6, HNPCC5, DNA mismatch repair protein Msh6, MSH-6, p160, sperm-associated protein, LYNCH5, mutS-like protein 6, MMRCS3, GTBP, G/T mismatch-binding protein, HSAP, mutS-alpha 160 kDa subunit, truncated MSH6
Source: HGNC:7329
Biotype: protein coding gene

RPA1

(Homo sapiens)
Gene
Name: replication protein A1
Synonyms: replication protein A 70 kDa DNA-binding subunit, replication factor A protein 1, RF-A protein 1, REPA1, MSTP075, PFBMFT6, RF-A, replication protein A1, 70kDa, RP-A, RPA70, RP-A p70, HSSB, MST075, single-stranded DNA-binding protein
Source: HGNC:10289
Biotype: protein coding gene

Trp63

(Mus musculus)
Gene
Name: transformation related protein 63
Synonyms: expressed sequence AI462811, p53-related protein 1, P73l, KET protein, Tp73l, Trp53rp1, p63, AI462811, p73L, deltaNp63, Ket, TAp63, p51/p63
Source: MGI:1330810
Biotype: protein coding gene

NEIL2

(Homo sapiens)
Gene
Name: nei like DNA glycosylase 2
Synonyms: MGC2832, nei like 2, NEI2, nei endonuclease VIII-like 2, NEH2, endonuclease 8-like 2, nei-like protein 2, FLJ31644, DNA glycosylase/AP lyase Neil2, endonuclease VIII-like 2, nei-like DNA glycosylase 2, nei homolog 2, DNA-(apurinic or apyrimidinic site) lyase Neil2, MGC4505
Source: HGNC:18956
Biotype: protein coding gene

Pold1

(Rattus norvegicus)
Gene
Name: DNA polymerase delta 1, catalytic subunit
Synonyms: polymerase (DNA) delta 1, catalytic subunit, DNA polymerase delta catalytic subunit, DAN polymerase delta 1, catalytic subunit, polymerase (DNA directed), delta 1, catalytic subunit, DNA polymerase delta, catalytic subunit, DNA-directed DNA polymerase delta 1, 3'-5' exodeoxyribonuclease
Source: RGD:621839
Biotype: protein coding gene

Msh2

(Mus musculus)
Gene
Name: mutS homolog 2
Synonyms: expressed sequence AI788990, AI788990
Source: MGI:101816
Biotype: protein coding gene

rev1

(Danio rerio)
Gene
Name: REV1 DNA directed polymerase
Synonyms: si:dkey-57a22.7
Source: ZFIN:ZDB-GENE-081105-180
Biotype: protein coding gene

Ep300

(Rattus norvegicus)
Gene
Name: E1A binding protein p300
Synonyms: histone acetyltransferase p300
Source: RGD:620036
Biotype: protein coding gene

Neil3

(Mus musculus)
Gene
Name: nei like 3 (E. coli)
Synonyms: MGC:27861, MGC:36916, RGD1310562, AI449477, expressed sequence AI449477, expressed sequence C85903, BC034753, C85903, cDNA sequence BC034753
Source: MGI:2384588
Biotype: protein coding gene

Neil2

(Mus musculus)
Gene
Name: nei like 2 (E. coli)
Synonyms: NEH2, gene model 1212, (NCBI), Gm1212, LOC382913
Source: MGI:2686058
Biotype: protein coding gene

Dclre1a

(Mus musculus)
Gene
Name: DNA cross-link repair 1A
Synonyms: SMN1a, 2810043H12Rik, expressed sequence AU022226, AU022226, SNM1, mSNM1, RIKEN cDNA 2810043H12 gene
Source: MGI:1930042
Biotype: protein coding gene

RFA1

(Saccharomyces cerevisiae)
Gene
Name: Replication Factor A
Synonyms: BUF2, RPA70, FUN3, RPA1, YAR007C
Source: SGD:S000000065
Biotype: protein coding gene

xpa-1

(Caenorhabditis elegans)
Gene
Name: human XPA (Xeroderma pigmentosum comp grp A) related 1
Synonyms: K07G5.2, CELE_K07G5.2, rad-3
Source: WB:WBGene00006963
Biotype: protein coding gene

Crebbp

(Rattus norvegicus)
Gene
Name: CREB binding protein
Synonyms: CBP, RTS, CREB-binding protein, Creb binding protein (CBP), histone lysine acetyltransferase CREBBP, protein-lysine acetyltransferase CREBBP, RSTS
Source: RGD:2401
Biotype: protein coding gene

Pold1

(Mus musculus)
Gene
Name: polymerase (DNA directed), delta 1, catalytic subunit
Synonyms: 125kDa
Source: MGI:97741
Biotype: protein coding gene

Xpa

(Mus musculus)
Gene
Name: xeroderma pigmentosum, complementation group A
Synonyms: Xpac, expressed sequence AI573865, xeroderma pigmentosum, complementation group A correcting gene, AI573865
Source: MGI:99135
Biotype: protein coding gene

Ercc5

(Mus musculus)
Gene
Name: excision repair cross-complementing rodent repair deficiency, complementation group 5
Synonyms: xeroderma pigmentosum, complementation group G, Xpg
Source: MGI:103582
Biotype: protein coding gene

TDG

(Homo sapiens)
Gene
Name: thymine DNA glycosylase
Synonyms: G/T mismatch-specific thymine DNA glycosylase, thymine-DNA glycosylase, hTDG
Source: HGNC:11700
Biotype: protein coding gene

REV1

(Homo sapiens)
Gene
Name: REV1 DNA directed polymerase
Synonyms: AIBP80, DNA repair protein REV1, rev1-like (yeast), MGC26225, alpha integrin-binding protein 80, REV1, DNA directed polymerase, MGC163283, REV1, polymerase (DNA directed), rev1-like terminal deoxycytidyl transferase, REV1 homolog, REV1- like, FLJ21523, REV1L
Source: HGNC:14060
Biotype: protein coding gene

PSO2

(Saccharomyces cerevisiae)
Gene
Name: PSOralen derivative sensitive
Synonyms: YMR137C, SNM1
Source: SGD:S000004745
Biotype: protein coding gene

Sirt6

(Mus musculus)
Gene
Name: sirtuin 6
Synonyms: RIKEN cDNA 2810449N18 gene, expressed sequence AI043036, AI043036, 2810449N18Rik
Source: MGI:1354161
Biotype: protein coding gene

REV1

(Saccharomyces cerevisiae)
Gene
Name: REVersionless
Synonyms: YOR346W
Source: SGD:S000005873
Biotype: protein coding gene