Version: 8.0.0Date: Tue Jan 28 2025
Gene Molecular Function: CARD domain binding
NOD2
(Homo sapiens)Gene
Name: nucleotide binding oligomerization domain containing 2
Synonyms: BLAU, CD, caspase recruitment domain protein 15, caspase recruitment domain family, member 15, NOD2B, IBD1, YAOS, NOD-like receptor C2, ACUG, NLRC2, PSORAS1, nucleotide-binding oligomerization domain-containing protein 2, NLR family, CARD domain containing 2, nucleotide-binding oligomerization domain containing 2, BLAUS, caspase recruitment domain-containing protein 15, inflammatory bowel disease protein 1, Inflammatory bowel disease-1 (Crohn disease), CARD15, nucleotide-binding oligomerization domain 2, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2, CLR16.3
Source: HGNC:5331
Biotype: protein coding gene
RIPK2
(Homo sapiens)Gene
Name: receptor interacting serine/threonine kinase 2
Synonyms: CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase, receptor-interacting serine-threonine kinase 2, receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase, receptor interacting protein 2, GIG30, CCK, RIP-like-interacting CLARP kinase, CARD3, growth-inhibiting gene 30, CARDIAK, receptor-interacting protein 2, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, tyrosine-protein kinase RIPK2, RICK, CARD-carrying kinase, RIP-2, receptor-interacting serine/threonine-protein kinase 2, CARD-containing IL-1 beta ICE-kinase, RIP2
Source: HGNC:10020
Biotype: protein coding gene
CARD11
(Homo sapiens)Gene
Name: caspase recruitment domain family member 11
Synonyms: MGC133069, CARMA1, IMD11, BIMP3, CARD-containing MAGUK protein 1, IMD11A, PPBL, carma 1, caspase recruitment domain-containing protein 11, bcl10-interacting maguk protein 3, card-maguk protein 1, BENTA, caspase recruitment domain family, member 11
Source: HGNC:16393
Biotype: protein coding gene
CARD8
(Homo sapiens)Gene
Name: caspase recruitment domain family member 8
Synonyms: CARD inhibitor of NF-kappaB-activating ligands, caspase recruitment domain-containing protein 8, TUCAN, DACAR, MGC57162, DKFZp779L0366, caspase recruitment domain family, member 8, NDPP1, CARDINAL, FLJ18119, apoptotic protein NDPP1, NDPP, KIAA0955, tumor up-regulated CARD-containing antagonist of CASP9, Dakar, FLJ18121, tumor up-regulated CARD-containing antagonist of caspase nine
Source: HGNC:17057
Biotype: protein coding gene
Casp4
(Mus musculus)Gene
Name: caspase 4, apoptosis-related cysteine peptidase
Synonyms: ich-3, Caspase-11, capase 11, apoptosis-related cysteine protease, Casp11, caspase 11, apoptosis-related cysteine peptidase
Source: MGI:107700
Biotype: protein coding gene
Dronc
(Drosophila melanogaster)Gene
Name: Death regulator Nedd2-like caspase
Synonyms: dronc, CG8091, CG8090, caspase-9, Dronc, anon-EST:GressD6, Drosophila Caspase-9 homologue, anon-EST:GreesD6, Nedd2-like caspase, anon-WO0118547.313, Nedd 2-like caspase, Drosophila Nedd2-like caspase, DRONC, Nc, Nc\Dronc, Dronc/Casp9, Caspase-9-like
Source: FB:FBgn0026404
Biotype: protein coding gene
CASP1
(Homo sapiens)Gene
Name: caspase 1
Synonyms: caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase), interleukin 1-beta convertase, interleukin-1 beta convertase, IL1BC, ICE, interleukin 1-B converting enzyme, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), caspase-1 isoform alpha, P45, CASP-1, interleukin 1, beta, convertase, IL-1 beta-converting enzyme, IL-1BC, caspase-1, caspase 1, apoptosis-related cysteine peptidase, IL1B-convertase, CASP1 nirs variant 1, interleukin-1 beta-converting enzyme
Source: HGNC:1499
Biotype: protein coding gene
Casp1
(Mus musculus)Gene
Name: caspase 1
Synonyms: p45, interleukin 1 beta-converting enzyme, Il1bc, interleukin 1 beta convertase, Ice, ICE, Caspase-1
Source: MGI:96544
Biotype: protein coding gene
Mavs
(Mus musculus)Gene
Name: mitochondrial antiviral signaling protein
Synonyms: D430028G21Rik, RIKEN cDNA D430028G21 gene, Visa, IPS-1
Source: MGI:2444773
Biotype: protein coding gene
Irgm2
(Mus musculus)Gene
Name: immunity-related GTPase family M member 2
Synonyms: expressed sequence AI481100, Gtpi, AI481100, Iigp2, interferon inducible GTPase 2
Source: MGI:1926262
Biotype: protein coding gene
CASP4
(Homo sapiens)Gene
Name: caspase 4
Synonyms: Mih1, ICEREL-II, caspase 4, apoptosis-related cysteine peptidase, ICE(rel)II, protease ICH-2, TX, CASP-4, caspase 4, apoptosis-related cysteine protease, Mih1/TX, ICE(rel)-II, ICH-2, apoptotic cysteine protease Mih1/TX, caspase-4 isoform alpha, protease TX, caspase-4, ICE and Ced-3 homolog 2
Source: HGNC:1505
Biotype: protein coding gene
MAVS
(Homo sapiens)Gene
Name: mitochondrial antiviral signaling protein
Synonyms: CARD adaptor inducing IFN-beta, IFN-B promoter stimulator 1, IPS1, mitochondrial antiviral-signaling protein, FLJ27482, KIAA1271, virus-induced signaling adaptor variant 1a, DKFZp547C224, FLJ35386, virus-induced-signaling adapter, FLJ38051, virus-induced signaling adaptor, mitochondrial anti-viral signaling protein, IPS-1, DKFZp666M015, CARDIF, virus-induced signaling adapter variant 1b, interferon-beta promoter stimulator protein 1, CARD adapter inducing interferon beta, VISA, FLJ31698, MGC3260, FLJ41962, CARD adapter inducing interferon-beta, putative NF-kappa-B-activating protein 031N, interferon beta promoter stimulator protein 1
Source: HGNC:29233
Biotype: protein coding gene
Card14
(Mus musculus)Gene
Name: caspase recruitment domain family, member 14
Synonyms: CARMA2, Bimp2
Source: MGI:2386258
Biotype: protein coding gene
Card11
(Mus musculus)Gene
Name: caspase recruitment domain family, member 11
Synonyms: 2410011D02Rik, RIKEN cDNA 2410011D02 gene, CARMA1, 0610008L17Rik, BIMP3, RIKEN cDNA 0610008L17 gene
Source: MGI:1916978
Biotype: protein coding gene
Nod2
(Mus musculus)Gene
Name: nucleotide-binding oligomerization domain containing 2
Synonyms: RIKEN cDNA F830032C23 gene, caspase recruitment domain family, member 15, Card15, F830032C23Rik, Nlrc2
Source: MGI:2429397
Biotype: protein coding gene
CARD9
(Homo sapiens)Gene
Name: caspase recruitment domain family member 9
Synonyms: caspase recruitment domain family, member 9, caspase recruitment domain-containing protein 9, caspase recruitment domain protein 9, hCARD9, IMD103, CANDF2
Source: HGNC:16391
Biotype: protein coding gene
BCL10
(Homo sapiens)Gene
Name: BCL10 immune signaling adaptor
Synonyms: CARD-containing apoptotic signaling protein, BCL10, immune signaling adaptor, mammalian CARD-containing adapter molecule E10, mE10, CLAP, IMD37, B-cell lymphoma/leukemia 10, caspase-recruiting domain-containing protein, B-cell CLL/lymphoma 10, CARD containing molecule enhancing NF-kB, CED-3/ICH-1 prodomain homologous E10-like regulator, c-E10, ciper, cellular-E10, cellular homolog of vCARMEN, hCLAP, CARD-containing proapoptotic protein, cCARMEN, bcl-10, carmen, CARD-containing molecule enhancing NF-kappa-B, B cell CLL/lymphoma 10
Source: HGNC:989
Biotype: protein coding gene
Igtp
(Mus musculus)Gene
Name: interferon gamma induced GTPase
Synonyms: AW558444, expressed sequence AW558444, Irgm3
Source: MGI:107729
Biotype: protein coding gene
Card9
(Mus musculus)Gene
Name: caspase recruitment domain family, member 9
Synonyms: Gm782, LOC332579, gene model 782, (NCBI)
Source: MGI:2685628
Biotype: protein coding gene
Nod1
(Mus musculus)Gene
Name: nucleotide-binding oligomerization domain containing 1
Synonyms: RGD1562269, F830007N14Rik, caspase recruitment domain 4, Card4, RIKEN cDNA F830007N14 gene, Nlrc1
Source: MGI:1341839
Biotype: protein coding gene
Ripk2
(Mus musculus)Gene
Name: receptor (TNFRSF)-interacting serine-threonine kinase 2
Synonyms: CARDIAK, 2210420D18Rik, D4Bwg0615e, DNA segment, Chr 4, Brigham & Women's Genetics 0615 expressed, RICK, CCK, RIKEN cDNA 2210420D18 gene, CARD3, RIP2
Source: MGI:1891456
Biotype: protein coding gene
ripk2
(Danio rerio)Gene
Name: receptor-interacting serine-threonine kinase 2
Synonyms: Ripk2, RICK
Source: ZFIN:ZDB-GENE-030902-3
Biotype: protein coding gene
CARD19
(Homo sapiens)Gene
Name: caspase recruitment domain family member 19
Synonyms: MGC110898, BinCARD, bA370F5.1, bcl10-interacting CARD protein, caspase recruitment domain family, member 19, C9orf89, caspase recruitment domain-containing protein 19, Bcl10-interacting protein with CARD, MGC11115
Source: HGNC:28148
Biotype: protein coding gene
Casp4
(Rattus norvegicus)Gene
Name: caspase 4
Synonyms: caspase 4, apoptosis-related cysteine peptidase, MGC124949, caspase 11, Casp11
Source: RGD:621757
Biotype: protein coding gene
Card14
(Rattus norvegicus)Gene
Name: caspase recruitment domain family, member 14
Synonyms: LOC688292, caspase recruitment domain-containing protein 14, similar to caspase recruitment domain family, member 14
Source: RGD:1591135
Biotype: protein coding gene
Irgm1
(Mus musculus)Gene
Name: immunity-related GTPase family M member 1
Synonyms: immunity-related GTPase family, M, interferon inducible protein 1, Ifggd3, Ifi1, LRG-47, Irgm, Iigp3
Source: MGI:107567
Biotype: protein coding gene
Dark
(Drosophila melanogaster)Gene
Name: Death-associated APAF1-related killer
Synonyms: Hac-1/Dark, Apaf-1-related-killer, dark/dapaf-1/hac-1, Dapaf-1/HAC-1, D-Apaf-1, Apaf-1-Related Killer, dApaf-1, anon-53Fa, lethal (2) SH0173, l(2)SH0173, apaf1, Drosophila Apaf-1-related killer, Apaf-1, Dark/Hac-1/dApaf1, apaf1-related killer, APAF1, Hac1, Dark/Hac-1/dApaf-1, Hac-1, Apaf, Apaf1, Dark, Transcription unit 1, ARK, Dark/Apaf-I, CG6829, Ark, dark/hac-1/dapaf-1, Apaf-1 related killer, APAF-1, hac-1, dapaf-1, arc, Dark/Dapaf-1/HAC1, dapaf, hac1, dark, Apaf-1 related, ark, dpf, dApaf-1/DARK/HAC-1, T1, dapaf-1S, apaf-1, Apaf-1-related killer, dapaf-1L, DARK, dApaf1, dArk, Dapaf-1, dAPAF-1
Source: FB:FBgn0263864
Biotype: protein coding gene
Irgm
(Rattus norvegicus)Gene
Name: immunity-related GTPase M
Synonyms: interferon-gamma-inducible GTPase Ifggd3 protein, immunity-related GTPase family, M, interferon inducible protein 1, Ifggd3, LOC303090, Ifi1, immunity-related GTPase family M protein
Source: RGD:1305163
Biotype: protein coding gene
Fadd
(Drosophila melanogaster)Gene
Name: Fas-associated death domain
Synonyms: FAD, Fas-associated death domain ortholog, BG4, DmFADD, dfadd, fadd, BG4_DROME, CG12297, Fadd, FADD, dFadd, dFADD, Fas-associated death domain
Source: FB:FBgn0038928
Biotype: protein coding gene
CARD14
(Homo sapiens)Gene
Name: caspase recruitment domain family member 14
Synonyms: caspase recruitment domain family, member 14, PSS1, CARMA2, CARD-containing MAGUK 2 protein, BIMP2, CARD-containing MAGUK protein 2, PRP, carma 2, caspase recruitment domain-containing protein 14, psoriasis susceptibility 2, bcl10-interacting maguk protein 2, card-maguk protein 2, FLJ38097, PSORS2
Source: HGNC:16446
Biotype: protein coding gene
Card11
(Rattus norvegicus)Gene
Name: caspase recruitment domain family, member 11
Synonyms: caspase recruitment domain-containing protein 11, LOC100363332
Source: RGD:2323211
Biotype: protein coding gene
Bcl10
(Mus musculus)Gene
Name: B cell leukemia/lymphoma 10
Synonyms: expressed sequence C81403, BCL-10, mE10, C81403, expressed sequence AI132454, AI132454, cE10
Source: MGI:1337994
Biotype: protein coding gene
Nod1
(Rattus norvegicus)Gene
Name: nucleotide-binding oligomerization domain containing 1
Synonyms: RGD1562269, LOC500133, nucleotide-binding oligomerization domain-containing protein 1, similar to Caspase recruitment domain protein 4
Source: RGD:1562269
Biotype: protein coding gene
Casp1
(Rattus norvegicus)Gene
Name: caspase 1
Synonyms: interleukin-1 beta convertase, interleukin 1 beta convertase, caspase 1 apoptosis-related cysteine protease (interleukin 1 beta convertase), Ice, p45, CASP-1, interleukin 1, beta, convertase, IL-1 beta-converting enzyme, Il1bc, Interleukin 1beta converting enzyme, caspase-1, IL-1BC, interleukin-1 beta-converting enzyme
Source: RGD:2274
Biotype: protein coding gene
Mavs
(Rattus norvegicus)Gene
Name: mitochondrial antiviral signaling protein
Synonyms: virus-induced-signaling adapter, virus-induced signaling adapter, interferon-beta promoter stimulator protein 1, mitochondrial antiviral-signaling protein, virus-induced signaling adaptor, Visa, IPS-1, interferon beta promoter stimulator protein 1, similar to RIKEN cDNA D430028G21, MGC93707
Source: RGD:1359371
Biotype: protein coding gene
Ripk2
(Rattus norvegicus)Gene
Name: receptor-interacting serine-threonine kinase 2
Synonyms: receptor (TNFRSF)-interacting serine-threonine kinase 2, LOC362491, receptor-interacting serine/threonine-protein kinase 2
Source: RGD:1309167
Biotype: protein coding gene
IRGM
(Homo sapiens)Gene
Name: immunity related GTPase M
Synonyms: LRG-47-like protein, immunity-related GTPase M, immunity-related GTPase family, M1, IFI1, IRGM1, immunity-related GTPase family M protein 1, immunity-related GTPase family M protein, IBD19, LRG47, immunity-related GTPase family, M, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG-47, MGC149264, MGC149263, interferon-inducible protein 1
Source: HGNC:29597
Biotype: protein coding gene
nod1
(Danio rerio)Gene
Name: nucleotide-binding oligomerization domain containing 1
Synonyms: NLR-A1
Source: ZFIN:ZDB-GENE-071116-9
Biotype: protein coding gene
CARD16
(Homo sapiens)Gene
Name: caspase recruitment domain family member 16
Synonyms: caspase recruitment domain family, member 16, pseudo interleukin-1beta converting enzyme, PSEUDO-ICE, caspase recruitment domain-only protein 1, caspase-1 dominant-negative inhibitor pseudo-ICE, COP, pseudo-IL1B-converting enzyme, CARD only domain-containing protein 1, COP1, pseudo interleukin-1 beta converting enzyme, CARD only protein, CARD-only protein 1, caspase recruitment domain-containing protein 16, caspase-1 inhibitor COP, LLID-114769
Source: HGNC:33701
Biotype: protein coding gene
Bcl10
(Rattus norvegicus)Gene
Name: BCL10, immune signaling adaptor
Synonyms: RCD, R-RCD1, B-cell leukemia/lymphoma 10, B-cell lymphoma/leukemia 10, bcl-10, B-cell CLL/lymphoma 10
Source: RGD:620544
Biotype: protein coding gene
nod2
(Danio rerio)Gene
Name: nucleotide-binding oligomerization domain containing 2
Synonyms: NLR-A2, card15
Source: ZFIN:ZDB-GENE-061108-4
Biotype: protein coding gene
NOD1
(Homo sapiens)Gene
Name: nucleotide binding oligomerization domain containing 1
Synonyms: NLR family, CARD domain containing 1, caspase recruitment domain-containing protein 4, nucleotide-binding oligomerization domain containing 1, CLR7.1, hNod1, CARD4, NLRC1, caspase recruitment domain family, member 4, nucleotide-binding oligomerization domain-containing protein 1, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1
Source: HGNC:16390
Biotype: protein coding gene
CARD18
(Homo sapiens)Gene
Name: caspase recruitment domain family member 18
Synonyms: caspase-1 inhibitor Iceberg, caspase recruitment domain family, member 18, ICEBERG, UNQ5804, caspase recruitment domain-containing protein 18, pseudo-ICE, ICEBERG caspase-1 inhibitor
Source: HGNC:28861
Biotype: protein coding gene
Card9
(Rattus norvegicus)Gene
Name: caspase recruitment domain family, member 9
Synonyms: rCARD9, caspase recruitment domain-containing protein 9, LOC64171, caspase recruitment domain protein 9
Source: RGD:708370
Biotype: protein coding gene
Nod2
(Rattus norvegicus)Gene
Name: nucleotide-binding oligomerization domain containing 2
Synonyms: caspase recruitment domain family, member 15, Card15, LOC291912, nucleotide-binding oligomerization domain-containing protein 2
Source: RGD:1306368
Biotype: protein coding gene