Version: 8.0.0Date: Tue Jan 28 2025
Gene Molecular Function: peptidase activator activity
Wdr20
(Mus musculus)Gene
Name: WD repeat domain 20
Synonyms: RIKEN cDNA 2310040A13 gene, 2310040A13Rik, Wdr20a, WD repeat domain 20A, expressed sequence AI549910, AI549910
Source: MGI:1916891
Biotype: protein coding gene
Nlrp3
(Rattus norvegicus)Gene
Name: NLR family, pyrin domain containing 3
Synonyms: PYRIN-containing APAF1-like protein 1, cryopyrin, cold autoinflammatory syndrome 1 homolog (human), cold autoinflammatory syndrome 1 homolog, Cias1, mast cell maturation-associated-inducible protein 1, cold autoinflammatory syndrome 1, NACHT, LRR and PYD domains-containing protein 3, cold autoinflammatory syndrome 1 protein homolog, LOC287362
Source: RGD:1308314
Biotype: protein coding gene
ced-3
(Caenorhabditis elegans)Gene
Name: CEll Death abnormality 3
Synonyms: CELE_C48D1.2, C48D1.2
Source: WB:WBGene00000417
Biotype: protein coding gene
ATP2A3
(Homo sapiens)Gene
Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
Synonyms: SR Ca(2+)-ATPase 3, SERCA3, calcium pump 3, sarcoplasmic/endoplasmic reticulum calcium ATPase 3, ATPase, Ca++ transporting, ubiquitous, sarco/endoplasmic reticulum Ca2+ -ATPase, adenosine triphosphatase, calcium, sarco/endoplasmic reticulum Ca2+ ATPase, ATPase, Ca(2+)-transporting, ubiquitous, calcium-translocating P-type ATPase
Source: HGNC:813
Biotype: protein coding gene
bur
(Drosophila melanogaster)Gene
Name: burgundy
Synonyms: GMP-synthetase, l(2)10523, GMPS, Gmps, CG9242, gua2, anon-WO0118547.204, GMP synthetase, anon-WO0118547.193, P174, ES2-2, Bur, Enhancer of GMR-sina 2-2
Source: FB:FBgn0000239
Biotype: protein coding gene
Nkx3-1
(Mus musculus)Gene
Name: NK3 homeobox 1
Synonyms: NKX3A, NKX3.1, Bax, Nkx-3.1, bagpipe, Nkx3.1
Source: MGI:97352
Biotype: protein coding gene
Pcolce
(Mus musculus)Gene
Name: procollagen C-endopeptidase enhancer protein
Synonyms: Astt-2, Astt2, astroglial cell transcript 2, PCPE
Source: MGI:105099
Biotype: protein coding gene
Rock2
(Mus musculus)Gene
Name: Rho-associated coiled-coil containing protein kinase 2
Synonyms: ROKalpha, Rock-II, B230113H15Rik, ROCK-II, Rho-kinase, Rock2m, RIKEN cDNA B230113H15 gene, ROK
Source: MGI:107926
Biotype: protein coding gene
APAF1
(Homo sapiens)Gene
Name: apoptotic peptidase activating factor 1
Synonyms: DKFZp781B1145, apoptotic protease activating factor 1, APAF-1, CED4, apoptotic protease-activating factor 1
Source: HGNC:576
Biotype: protein coding gene
NLRP12
(Homo sapiens)Gene
Name: NLR family pyrin domain containing 12
Synonyms: PYPAF7, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12, monarch-1, NALP12, NACHT, LRR and PYD containing protein 12, NACHT, LRR and PYD domains-containing protein 12, RNO, regulated by nitric oxide, NLR family, pyrin domain containing 12, RNO2, FCAS2, CLR19.3, PYRIN-containing APAF1-like protein 7, PAN6, monarch 1
Source: HGNC:22938
Biotype: protein coding gene
Psenen
(Mus musculus)Gene
Name: presenilin enhancer gamma secretase subunit
Synonyms: RGD1312037, RIKEN cDNA 1700023M09 gene, Pen2, 1700023M09Rik
Source: MGI:1913590
Biotype: protein coding gene
Tifab
(Mus musculus)Gene
Name: TRAF-interacting protein with forkhead-associated domain, family member B
Synonyms: cDNA sequence BC027057, BC027057, RGD1311681, MGC:32345, MGC:37193
Source: MGI:2385852
Biotype: protein coding gene
ctsh
(Danio rerio)Gene
Name: cathepsin H
Synonyms: wu:fc44c02, zgc:85774, fc44c02
Source: ZFIN:ZDB-GENE-030131-3539
Biotype: protein coding gene
PSME2
(Homo sapiens)Gene
Name: proteasome activator subunit 2
Synonyms: protease (prosome, macropain) 28 subunit, beta, 11S regulator complex subunit beta, activator of multicatalytic protease subunit 2, proteasome activator hPA28 subunit beta, proteasome activator 28 subunit beta, PA28B, PA28beta, cell migration-inducing protein 22, REG-beta, REGbeta, proteasome activator 28-beta, proteasome activator complex subunit 2, 11S regulator complex beta subunit, proteasome (prosome, macropain) activator subunit 2 (PA28 beta), MCP activator, 31-kD subunit
Source: HGNC:9569
Biotype: protein coding gene
FGL2
(Homo sapiens)Gene
Name: fibrinogen like 2
Synonyms: fibrinogen-like 2, T49, fibroleukin, pT49, fibrinogen-like protein 2
Source: HGNC:3696
Biotype: protein coding gene
Psme4
(Mus musculus)Gene
Name: proteasome (prosome, macropain) activator subunit 4
Synonyms: AU041366, expressed sequence AU041366, b2b1508Clo, expressed sequence AA409398, AA409398
Source: MGI:2143994
Biotype: protein coding gene
RPS27L
(Homo sapiens)Gene
Name: ribosomal protein S27 like
Synonyms: 40S ribosomal protein S27-like, ribosomal protein S27-like, ribosomal protein eS27-like, small ribosomal subunit protein eS27-like
Source: HGNC:18476
Biotype: protein coding gene
CLPX
(Homo sapiens)Gene
Name: caseinolytic mitochondrial matrix peptidase chaperone subunit X
Synonyms: ClpX caseinolytic protease X homolog, clpx caseinolytic protease x homolog (e. coli), ClpX caseinolytic peptidase X homolog, energy-dependent regulator of proteolysis, ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, EPP2, caseinolytic mitochondrial matrix peptidase chaperone subunit
Source: HGNC:2088
Biotype: protein coding gene
Nlrp1b
(Rattus norvegicus)Gene
Name: NLR family, pyrin domain containing 1B
Synonyms: NACHT, LRR and PYD domains-containing protein 1b allele 3-like, LOC691998, similar to NACHT, leucine rich repeat and PYD containing 1, AABR07029890.1
Source: RGD:1593294
Biotype: protein coding gene
Psme3
(Mus musculus)Gene
Name: proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
Synonyms: AU020960, Ab2-371, pa28g, AA410043, expressed sequence AU020960, REGgamma, Ki, expressed sequence AA410043, PA28gamma
Source: MGI:1096366
Biotype: protein coding gene
Apaf1
(Mus musculus)Gene
Name: apoptotic peptidase activating factor 1
Synonyms: forebrain overgrowth, 6230400I06Rik, Apaf1l, apoptotic protease activating factor 1 like, RIKEN cDNA 6230400I06 gene, fog
Source: MGI:1306796
Biotype: protein coding gene
Malt1
(Rattus norvegicus)Gene
Name: MALT1 paracaspase
Synonyms: mucosa associated lymphoid tissue lymphoma translocation gene 1, paracaspase-1, Pcasp1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, paracaspase 1, LOC307366
Source: RGD:1309195
Biotype: protein coding gene
NKX3-1
(Homo sapiens)Gene
Name: NK3 homeobox 1
Synonyms: NK3 transcription factor related, locus 1, homeobox protein Nkx-3.1, NKX3A, NKX3.1, BAPX2, NK3 transcription factor homolog A, NKX3, homeobox protein NK-3 homolog A, NK homeobox, family 3, A
Source: HGNC:7838
Biotype: protein coding gene
PCOLCE
(Homo sapiens)Gene
Name: procollagen C-endopeptidase enhancer
Synonyms: type 1 procollagen C-proteinase enhancer protein, procollagen C-endopeptidase enhancer 1, procollagen C-proteinase enhancer 1, type I procollagen COOH-terminal proteinase enhancer, PCPE-1, procollagen, type 1, COOH-terminal proteinase enhancer, procollagen COOH-terminal proteinase enhancer 1, PCPE, PCPE1
Source: HGNC:8738
Biotype: protein coding gene
Sfrp2
(Mus musculus)Gene
Name: secreted frizzled-related protein 2
Synonyms: AI851596, expressed sequence AI851596, Sdf5, stromal cell derived factor 5
Source: MGI:108078
Biotype: protein coding gene
CFLAR
(Homo sapiens)Gene
Name: CASP8 and FADD like apoptosis regulator
Synonyms: cFLIP, c-FLIPL, caspase-related inducer of apoptosis, c-FLIPR, c-FLIPS, FLIP, I-FLICE, caspase-like apoptosis regulatory protein, usurpin beta, cellular FLICE-like inhibitory protein, caspase homolog, c-FLIP, CASP8AP1, testis secretory sperm-binding protein Li 233m, CLARP, CASP8 and FADD-like apoptosis regulator, inhibitor of FLICE, Casper, FLAME-1, CASH, MACH-related inducer of toxicity, FLAME, FADD-like anti-apoptotic molecule, caspase-eight-related protein, MRIT, FADD-like antiapoptotic molecule 1, FLAME1
Source: HGNC:1876
Biotype: protein coding gene
Psmd14
(Rattus norvegicus)Gene
Name: proteasome 26S subunit, non-ATPase 14
Synonyms: LOC311078, proteasome (prosome, macropain) 26S subunit, non-ATPase, 14, 26S proteasome non-ATPase regulatory subunit 14, MGC114474, LOC295644, similar to T-Brain-1
Source: RGD:1594532
Biotype: protein coding gene
pcolceb
(Danio rerio)Gene
Name: procollagen C-endopeptidase enhancer b
Synonyms: zgc:194993, zgc:195010
Source: ZFIN:ZDB-GENE-080722-44
Biotype: protein coding gene
BEX3
(Homo sapiens)Gene
Name: brain expressed X-linked 3
Synonyms: brain-expressed X-linked protein 3, HGR74, nerve growth factor receptor (TNFRSF16) associated protein 1, p75NTR-associated cell death executor, DXS6984E, ovarian granulosa cell protein (13kD), NADE, nerve growth factor receptor-associated protein 1, NGFRAP1, Bex, ovarian granulosa cell 13.0 kDa protein HGR74, brain expressed, X-linked 3, Hero20
Source: HGNC:13388
Biotype: protein coding gene
BAD
(Homo sapiens)Gene
Name: BCL2 associated agonist of cell death
Synonyms: BCL2L8, bcl2 antagonist of cell death, bcl-2-binding component 6, BCL2-associated agonist of cell death, BCL2-antagonist of cell death, bcl2-L-8, bcl-2-like protein 8, BCL-X/BCL-2 binding protein, BCL2-binding component 6, BBC2, bcl-XL/Bcl-2-associated death promoter, bcl-2 associated death agonist, BCL2-binding protein
Source: HGNC:936
Biotype: protein coding gene
NDUFA13
(Homo sapiens)Gene
Name: NADH:ubiquinone oxidoreductase subunit A13
Synonyms: cell death-regulatory protein GRIM19, complex I-B16.6, CDA016, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13, complex I B16.6 subunit, NADH-ubiquinone oxidoreductase B16.6 subunit, MC1DN28, CI-B16.6, CGI-39, cell death regulatory protein GRIM-19, gene associated with retinoic and IFN-induced mortality 19 protein, GRIM-19, gene associated with retinoic and interferon-induced mortality 19 protein, B16.6, FLJ59191, GRIM19, FLJ58045, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
Source: HGNC:17194
Biotype: protein coding gene
WDR48
(Homo sapiens)Gene
Name: WD repeat domain 48
Synonyms: UAF1, USP1-associated factor 1, KIAA1449, SPG60, testicular tissue protein Li 224, WD repeat-containing protein 48, P80, WD repeat endosomal protein, USP1 associated factor 1, Bun62, DKFZp686G1794
Source: HGNC:30914
Biotype: protein coding gene
CTSS
(Homo sapiens)Gene
Name: cathepsin S
Synonyms: FLJ50259, MGC3886
Source: HGNC:2545
Biotype: protein coding gene
CTSK
(Homo sapiens)Gene
Name: cathepsin K
Synonyms: cathepsin O1, cathepsin O, CTSO2, CTSO, CTSO1, CTS02, PKND, cathepsin X, MGC23107, PYCD, cathepsin O2
Source: HGNC:2536
Biotype: protein coding gene
Psme1
(Mus musculus)Gene
Name: proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
Synonyms: expressed sequence AW413925, AW413925, PA28a
Source: MGI:1096367
Biotype: protein coding gene
BRO1
(Saccharomyces cerevisiae)Gene
Name: BCK1-like Resistance to Osmotic shock
Synonyms: ASI6, YPL084W, LPF2, VPS31, NPI3
Source: SGD:S000006005
Biotype: protein coding gene
PSME1
(Homo sapiens)Gene
Name: proteasome activator subunit 1
Synonyms: interferon-gamma-inducible protein 5111, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha), 11S regulator complex alpha subunit, interferon-gamma IEF SSP 5111, proteasome activator 28 subunit alpha, REGalpha, 29-kD MCP activator subunit, REG-alpha, interferon gamma up-regulated I-5111 protein, 11S regulator complex subunit alpha, PA28A, epididymis secretory sperm binding protein Li 129m, HEL-S-129m, protease (prosome, macropain) 28 subunit, alpha, PA28alpha, activator of multicatalytic protease subunit 1, proteasome activator subunit-1, proteasome activator complex subunit 1, IGUP I-5111, IFI5111, MGC8628
Source: HGNC:9568
Biotype: protein coding gene
fbl-1
(Caenorhabditis elegans)Gene
Name: FiBuLin 1
Synonyms: CELE_F56H11.1, FBLN1, F56H11.1
Source: WB:WBGene00001403
Biotype: protein coding gene
Rack1
(Rattus norvegicus)Gene
Name: receptor for activated C kinase 1
Synonyms: receptor for activated protein kinase C, guanine nucleotide binding protein, beta polypeptide 2-like 1, guanine nucleotide binding protein (G protein) beta polypeptide 2-like 1, receptor of activated protein C kinase 1, protein kinase C receptor, small ribosomal subunit protein RACK1, receptor of activated protein kinase C 1, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1, receptor for activated C kinase, Gnb2l1, guanine nucleotide-binding protein subunit beta-2-like 1
Source: RGD:69229
Biotype: protein coding gene
Fn1
(Rattus norvegicus)Gene
Name: fibronectin 1
Synonyms: fibronectin 2, fibronectin 3, fibronectin, FN, FIBNEC, fn-1
Source: RGD:2624
Biotype: protein coding gene
ttm50
(Drosophila melanogaster)Gene
Name: tiny tim 50
Synonyms: i90, EG:95B7.3, Gp99, 17944223, Ttm50, i238, CG2713
Source: FB:FBgn0250874
Biotype: protein coding gene
BLM10
(Saccharomyces cerevisiae)Gene
Name: BLeoMycin resistance
Synonyms: YFL006W, YFL007W
Source: SGD:S000001887
Biotype: protein coding gene
TANK
(Homo sapiens)Gene
Name: TRAF family member associated NFKB activator
Synonyms: ITRAF, I-TRAF, traf family member-associated nf-kappa b activator, TRAF family member-associated NFKB activator, TRAF2, TRAF-interacting protein, TRAF family member-associated NF-kappa-B activator
Source: HGNC:11562
Biotype: protein coding gene
Nlrp1b
(Mus musculus)Gene
Name: NLR family, pyrin domain containing 1B
Synonyms: predicted gene, ENSMUSG00000070390, predicted gene, OTTMUSG00000006087, OTTMUSG00000006089, OTTMUSG00000006087, Nalp1b, AABR07029890.1, predicted gene, OTTMUSG00000006089, ENSMUSG00000070390
Source: MGI:3582959
Biotype: protein coding gene
Ctsc
(Mus musculus)Gene
Name: cathepsin C
Synonyms: dipeptidylpeptidase 1, CATC, expressed sequence AI047818, DPP-I, DPPI, AI047818, DPP1
Source: MGI:109553
Biotype: protein coding gene
DMWD
(Homo sapiens)Gene
Name: DM1 locus, WD repeat containing
Synonyms: protein 59, DMR-N9, DMRN9, dystrophia myotonica-containing wd repeat motif, gene59, dystrophia myotonica, WD repeat containing, D19S593E, dystrophia myotonica WD repeat-containing protein
Source: HGNC:2936
Biotype: protein coding gene
CASP8AP2
(Homo sapiens)Gene
Name: caspase 8 associated protein 2
Synonyms: KIAA1315, CASP8-associated protein 2, human FLASH, FLASH homolog RIP25, RIP25, CASP8 associated protein 2, CED-4, FLICE associated huge, FLJ11208, FLICE-associated huge protein, FLASH
Source: HGNC:1510
Biotype: protein coding gene
CTSV
(Homo sapiens)Gene
Name: cathepsin V
Synonyms: MGC125957, CATL2, cathepsin L2, preproprotein, cathepsin U, CTSU, cathepsin L2, CTSL2
Source: HGNC:2538
Biotype: protein coding gene
Hspd1
(Rattus norvegicus)Gene
Name: heat shock protein family D (Hsp60) member 1
Synonyms: mitochondrial matrix protein P1, heat shock protein 60 (liver), CPN60, HSP-60, heat shock protein 1 (chaperonin), 60 kDa heat shock protein, mitochondrial, Hsp60, heat shock 60kDa protein 1, Hspd1-30p, HSP-65, 60 kDa chaperonin, heat shock 60kD protein 1 (chaperonin), heat shock protein family D member 1, chaperonin 60
Source: RGD:621314
Biotype: protein coding gene
psme4a
(Danio rerio)Gene
Name: proteasome activator subunit 4a
Synonyms: si:ch73-101f17.1
Source: ZFIN:ZDB-GENE-091204-452
Biotype: protein coding gene