Version: 8.0.0Date: Tue Jan 28 2025
Category
cblb
(Danio rerio)Gene
Name: Cbl proto-oncogene B, E3 ubiquitin protein ligase
Synonyms: si:dz39l02.2, si:dz25n23.1, si:busm1-39l02.2, si:busm1-25n23.1
Source: ZFIN:ZDB-GENE-030616-417
Biotype: protein coding gene
Symbol: cblb (Dre)
Symbol: cblb
Automated Gene Synopsis: Orthologous to human CBLB (Cbl proto-oncogene B).
Strict Orthology Symbols: cblb
Cblb
(Rattus norvegicus)Gene
Name: Cbl proto-oncogene B
Synonyms: RING-type E3 ubiquitin transferase CBL-B, SH3-binding protein CBL-B, casitas B-lineage lymphoma proto-oncogene b, Cbl proto-oncogene, E3 ubiquitin protein ligase B, signal transduction protein CBL-B, Cas-Br-M (murine) ectropic retroviral transforming sequence b, Cbl proto-oncogene B, E3 ubiquitin protein ligase, Casitas B-lineage lymphoma B, Cas-Br-M (murine) ecotropic retroviral transforming sequence b, E3 ubiquitin-protein ligase CBL-B
Source: RGD:620535
Biotype: protein coding gene
Symbol: Cblb (Rno)
Symbol: Cblb
Gene Synopsis: Orthologous to human CBLB (Cbl proto-oncogene B); PARTICIPATES IN chronic myeloid leukemia pathway; endocytosis
Automated Gene Synopsis: Orthologous to human CBLB (Cbl proto-oncogene B).
Strict Orthology Symbols: cblb
Cblb
(Mus musculus)Gene
Name: Casitas B-lineage lymphoma b
Synonyms: expressed sequence AI429560, AI851073, AI429560, Cbl-b, expressed sequence AI851073
Source: MGI:2146430
Biotype: protein coding gene
Symbol: Cblb (Mmu)
Symbol: Cblb
Automated Gene Synopsis: Orthologous to human CBLB (Cbl proto-oncogene B).
Strict Orthology Symbols: cblb
Alleles: Cblb
CBLB
(Homo sapiens)Gene
Name: Cbl proto-oncogene B
Synonyms: RING-type E3 ubiquitin transferase CBL-B, DKFZp779A0729, Nbla00127, casitas B-lineage lymphoma proto-oncogene b, RNF56, Cbl proto-oncogene, E3 ubiquitin protein ligase B, FLJ36865, RING finger protein 56, FLJ41152, ADMIO3, DKFZp686J10223, SH3-binding protein CBL-B, signal transduction protein CBL-B, DKFZp779F1443, Cas-Br-M (murine) ectropic retroviral transforming sequence b, Cbl proto-oncogene B, E3 ubiquitin protein ligase, Cas-Br-M (murine) ecotropic retroviral transforming sequence b, Cbl-b, E3 ubiquitin-protein ligase CBL-B
Source: HGNC:1542
Biotype: protein coding gene
Symbol: CBLB (Hsa)
Symbol: CBLB
Strict Orthology Symbols: cblb
cblb
(Xenopus tropicalis)Gene
Name: Cbl proto-oncogene B, E3 ubiquitin protein ligase
Synonyms: rnf56, Cbl proto-oncogene B, E3 ubiquitin protein ligase, cblb, cblb-b, cblb-a
Source: Xenbase:XB-GENE-1018102
Biotype: gene
Symbol: cblb
Symbol: cblb (Xtr)
Automated Gene Synopsis: Orthologous to human CBLB (Cbl proto-oncogene B).
Synonyms: cblb...cblb...cblb
Strict Orthology Symbols: cblb
cblb.S
(Xenopus laevis)Gene
Name: Cbl proto-oncogene B, E3 ubiquitin protein ligase
Synonyms: rnf56, Cbl proto-oncogene B, E3 ubiquitin protein ligase, cblb.S, cblb-b, cblb-a
Source: Xenbase:XB-GENE-6251770
Biotype: gene
Symbol: cblb.S (Xla)
Automated Gene Synopsis: Orthologous to human CBLB (Cbl proto-oncogene B).
Strict Orthology Symbols: cblb
Symbol: cblb.S
cblb.L
(Xenopus laevis)Gene
Name: Cbl proto-oncogene B, E3 ubiquitin protein ligase
Synonyms: rnf56, cblb.L, Cbl proto-oncogene B, E3 ubiquitin protein ligase, cblb-b, cblb-a
Source: Xenbase:XB-GENE-6251733
Biotype: gene
Symbol: cblb.L (Xla)
Automated Gene Synopsis: Orthologous to human CBLB (Cbl proto-oncogene B).
Strict Orthology Symbols: cblb
Symbol: cblb.L
Cblbem1Cya
(Mus musculus)Allele/Variant
Source: MGI:7582740
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbem1Cya
Cblbem1Gpt
(Mus musculus)Allele/Variant
Source: MGI:7296315
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbem1Gpt
Cblbtm1Pngr
(Mus musculus)Allele/Variant
Source: MGI:2180570
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbtm1Pngr
Cblbtm1Hua
(Mus musculus)Allele/Variant
Source: MGI:2180572
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbtm1Hua
Cblbtm1Wlan
(Mus musculus)Allele/Variant
Source: MGI:3762926
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbtm1Wlan
Cblbtm1a(KOMP)Wtsi
(Mus musculus)Allele/Variant
Source: MGI:4880973
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbtm1a(KOMP)Wtsi
Cblbtm1.1Ciphe
(Mus musculus)Allele/Variant
Source: MGI:6690622
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbtm1.1Ciphe
Cblbem2Cya
(Mus musculus)Allele/Variant
Source: MGI:7582741
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbem2Cya
Cblbem1Smoc
(Mus musculus)Allele/Variant
Source: MGI:7288666
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbem1Smoc
Cblbem2Smoc
(Mus musculus)Allele/Variant
Source: MGI:7288667
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbem2Smoc
Cblbtm1c(KOMP)Wtsi
(Mus musculus)Allele/Variant
Source: MGI:6416122
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbtm1c(KOMP)Wtsi
Cblbtm1Hua/Cblbtm1Hua [background:] B6.129P2-Cblbtm1Hua
(Mus musculus)Model
Id: MGI:3525206
Synonyms: Not Available
Symbol: Cblb/Cblb [background:] B6.129P2-Cblb (Mmu)
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cblb/Cblb [background:] B6.129P2-Cblb
Cblbtm1Pngr/Cblbtm1Pngr Itktm1Litt/Itktm1Litt [background:] B6.129-Itktm1Litt Cblbtm1Pngr
(Mus musculus)Model
Id: MGI:3841993
Synonyms: Not Available
Symbol: Cblb/Cblb Itk/Itk [background:] B6.129-Itk Cblb
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cblb/Cblb Itk/Itk [background:] B6.129-Itk Cblb
Model
Id: MGI:3528380
Synonyms: Not Available
Symbol: Cblb/Cblb Vav1/Vav1 Was/Was [background:] involves
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cblb/Cblb Vav1/Vav1 Was/Was [background:] involves
Cblbtm1Hua/Cblbtm1Hua Ubash3btm1Jni/Ubash3btm1Jni Ubash3atm1Jni/Ubash3atm1Jni [background:] Not Specified
(Mus musculus)Model
Id: MGI:3052005
Synonyms: Not Available
Symbol: Cblb/Cblb Ubash3b/Ubash3b Ubash3a/Ubash3a [background
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cblb/Cblb Ubash3b/Ubash3b Ubash3a/Ubash3a [background
Model
Id: MGI:3762927
Synonyms: Not Available
Symbol: Cblb/Cblb [background:] involves: 129X1/SvJ * C57BL/6 (Mmu)
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cblb/Cblb [background:] involves: 129X1/SvJ * C57BL/6
Cblbtm1Hua/Cblbtm1Hua [background:] Not Specified
(Mus musculus)Model
Id: MGI:3052006
Synonyms: Not Available
Symbol: Cblb/Cblb [background:] Not Specified (Mmu)
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cblb/Cblb [background:] Not Specified
Model
Id: MGI:3841992
Synonyms: Not Available
Symbol: Cblb/Cblb [background:] B6.129P2-Cblb (Mmu)
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cblb/Cblb [background:] B6.129P2-Cblb
Model
Id: MGI:3762928
Synonyms: Not Available
Symbol: Cblb/Cblb [background:] involves: 129 * C57BL/6 (Mmu)
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cblb/Cblb [background:] involves: 129 * C57BL/6
Model
Id: MGI:3528379
Synonyms: Not Available
Symbol: Cblb/Cblb Was/Was [background:] Not Specified (Mmu)
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cblb/Cblb Was/Was [background:] Not Specified
Cblbem1Geha
(Mus musculus)Allele/Variant
Source: MGI:7388208
Genes: Cblb (Mmu)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: Cblb
Genes: Cblb (Mmu)
Symbol: Cblbem1Geha
MMAB
(Homo sapiens)Gene
Name: metabolism of cobalamin associated B
Synonyms: corrinoid adenosyltransferase, cilia and flagella associated protein 23, ATP:co(I)rrinoid adenosyltransferase MMAB, MGC20496, cob(II)alamin adenosyltransferase, methylmalonic aciduria (cobalamin deficiency) cblB type, ATP:cob(I)alamin adenosyltransferase, cobinamide/cobalamin adenosyltransferase, aquocob(I)alamin vitamin B12s adenosyltransferase, ATP:corrinoid adenosyltransferase, cob(I)alamin adenosyltransferase, cob, methylmalonic aciduria type B protein, methylmalonic aciduria (cobalamin deficiency) type b, corrinoid adenosyltransferase MMAB, cblB, cob(II)yrinic acid a,c-diamide adenosyltransferase, cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial, CFAP23, ATR
Source: HGNC:19331
Biotype: protein coding gene
Gene Synopsis: Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB
Automated Gene Synopsis: Implicated in inherited metabolic disorder and methylmalonic acidemia cblB type.
Synonyms: cblB...methylmalonic aciduria (cobalamin deficiency) cblB type...cblB
Diseases: methylmalonic acidemia cblB type
sli-1
(Caenorhabditis elegans)Gene
Name: Suppressor of LIneage defect 1
Synonyms: M02A10.3, CELE_M02A10.3
Source: WB:WBGene00004829
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human CBL (Cbl proto-oncogene); CBLB (Cbl proto-oncogene B); and CBLC (Cbl proto-oncogene
Strict Orthology Symbols: cblb
Cbl
(Drosophila melanogaster)Gene
Name: Cbl proto-oncogene
Synonyms: D-Cbl L, v-Cbl, D-cblSHORT, dCbl, Dcbl, anon-WO0118547.68, F165, CG7043, D-CblL, Dv-cbl, Cbl, cbl, CBL, Dv-Cbl, D-cbl, Cbl proto-oncogene ortholog, d-cbl, DCbl, D-Cbl, CG7037, D-cblL, D-cblLONG, cable, D-cblS
Source: FB:FBgn0020224
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to several human genes including CBL (Cbl proto-oncogene) and CBLB (Cbl proto-oncogene B)
Strict Orthology Symbols: cblb
mmab-1
(Caenorhabditis elegans)Gene
Name: MethylMalonic Aciduria type B homolog 1
Synonyms: C26E6.a, C26E6.11, CELE_C26E6.11, tag-339
Source: WB:WBGene00016144
Biotype: protein coding gene
Automated Gene Synopsis: Human ortholog(s) of this gene implicated in inherited metabolic disorder and methylmalonic acidemia cblB
Diseases: methylmalonic acidemia cblB type
mmab
(Danio rerio)Gene
Name: metabolism of cobalamin associated B
Synonyms: si:dkey-189p24.5
Source: ZFIN:ZDB-GENE-060526-232
Biotype: protein coding gene
Automated Gene Synopsis: Human ortholog(s) of this gene implicated in inherited metabolic disorder and methylmalonic acidemia cblB
Diseases: methylmalonic acidemia cblB type
Mmab
(Rattus norvegicus)Gene
Name: metabolism of cobalamin associated B
Synonyms: corrinoid adenosyltransferase, methylmalonic aciduria (cobalamin deficiency) type B homolog (human), similar to methylmalonic aciduria (cobalamin deficiency) type B homolog, corrinoid adenosyltransferase MMAB, methylmalonic aciduria (cobalamin deficiency) type B homolog, cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial, methylmalonic aciduria (cobalamin deficiency) cblB type
Source: RGD:1596242
Biotype: protein coding gene
Gene Synopsis: Human ortholog(s) of this gene implicated in inherited metabolic disorder and methylmalonic acidemia cblB
Automated Gene Synopsis: Human ortholog(s) of this gene implicated in inherited metabolic disorder and methylmalonic acidemia cblB
Synonyms: methylmalonic aciduria (cobalamin deficiency) cblB type
Diseases: methylmalonic acidemia cblB type
Mmab
(Mus musculus)Gene
Name: methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)
Synonyms: RIKEN cDNA 9130222L19 gene, 9130222L19Rik, ATP:Cob(I)alamin Adenosyltransferase
Source: MGI:1924947
Biotype: protein coding gene
Automated Gene Synopsis: Human ortholog(s) of this gene implicated in inherited metabolic disorder and methylmalonic acidemia cblB
Diseases: methylmalonic acidemia cblB type
mmab.L
(Xenopus laevis)Gene
Name: metabolism of cobalamin associated B
Synonyms: mmab.L, metabolism of cobalamin associated B
Source: Xenbase:XB-GENE-6255016
Biotype: gene
Automated Gene Synopsis: Human ortholog(s) of this gene implicated in inherited metabolic disorder and methylmalonic acidemia cblB
Diseases: methylmalonic acidemia cblB type
Source: DOID:0060743
Definition: A methylmalonic acidemia characterized by autosomal recessive inheritance, defects in the synthesis of AdoCbl, vitamin B12 therapy responsiveness and that has_material_basis_in homozygous or compound heterozygous mutation in the MMAB gene on chromosome 12q24.
Symbol: methylmalonic acidemia cblB type
Synonyms: methylmalonic aciduria cblB type...methylmalonic aciduria, vitamin B12-responsive, due to defect in synthesis of adenosylcobalamin, cblB
Name: methylmalonic acidemia cblB type
Source: GO:2000583
Synonyms:
- regulation of PDGF receptor-alpha signaling pathway
- regulation of PDGFR-alpha signaling pathway
Branch: biological process
Genes: Cblb (Mmu)...Cblb (Rno)...CBLB (Hsa)
Gene Ontology
Source: GO:0002870
Synonyms:
- T lymphocyte anergy
- T-cell anergy
Branch: biological process
Genes: Cblb (Mmu)...Cblb (Rno)...CBLB (Hsa)
Gene Ontology
Source: GO:0035739
Synonyms: Not Available
Branch: biological process
Genes: Cblb (Mmu)...Cblb (Rno)...CBLB (Hsa)
Gene Ontology
Source: GO:0002669
Synonyms:
- activation of T cell anergy
- positive regulation of T lymphocyte anergy
Branch: biological process
Genes: Cblb (Mmu)...Cblb (Rno)...CBLB (Hsa)
Gene Ontology
Source: GO:0140252
Synonyms: Not Available
Branch: biological process
Genes: Cblb (Mmu)...Cblb (Rno)...CBLB (Hsa)
la010484Tg
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-120130-547
Genes: cblb (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: cblb (Dre)
Gene Ontology
Source: GO:0018193
Synonyms: Not Available
Branch: biological process
Genes: Cblb (Mmu)
la011840Tg
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-120806-8207
Genes: cblb (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: cblb (Dre)
Cbltm2Hua/Cbltm2Hua Cblbtm1Hua/Cblbtm1Hua Tg(Lck-cre)I57Jxm/0 [background:] involves: 129P2/OlaHsd * C57BL/6 * ICR
(Mus musculus)Model
Id: MGI:2652089
Synonyms: Not Available
Genes: Cblb (Mmu)
Alleles: Cblb
Name: Cbl/Cbl Cblb/Cblb Tg(Lck-cre)I57Jxm/0 [background:] involves: 129P2/
Symbol: Cbl/Cbl Cblb/Cblb Tg(Lck-cre)I57Jxm/0 [background:] involves: 129P2/
Gene Ontology
Source: GO:0023051
Synonyms:
- regulation of signaling process
- regulation of signalling process
Branch: biological process
Genes: cblb (Dre)...Cblb (Rno)...CBLB (Hsa)
Source: GO:2000562
Synonyms: Not Available
Branch: biological process
Genes: Cblb (Mmu)...Cblb (Rno)...CBLB (Hsa)
KDP-Tg(H2Kd-Cblb)1Nyo
(Rattus norvegicus)Model
Id: RGD:2304064
Synonyms: NBRP Rat No: 0196
Name: KDP-Tg(H2Kd-Cblb)1Nyo
Source: GO:0099149
Synonyms:
- regulation of postsynaptic neurotransmitter receptor endocytosis
Branch: biological process
Genes: Cblb (Mmu)...CBLB (Hsa)...Cblb (Rno)