Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
---|---|---|---|---|---|
Homo sapiens | HSD17B4 | 4 of 9 | Yes | Yes | ☑ ☑☐☐☐☑☐☐☑ |
Mus musculus | Hsd17b4 | 4 of 9 | Yes | Yes | ☑ ☑☐☐☐☑☐☐☑ |
Rattus norvegicus | Hsd17b4 | 4 of 9 | Yes | Yes | ☑ ☑☐☐☐☑☐☐☑ |
Xenopus tropicalis | hsd17b4 | 6 of 9 | Yes | Yes | ☑ ☑☑☐☑☑☐☑☐ |
Danio rerio | hsd17b4 | 4 of 9 | Yes | Yes | ☑ ☑☐☐☐☑☐☐☑ |
Drosophila melanogaster | Mfe2 | 5 of 9 | Yes | Yes | ☑ ☑☑☐☐☑☐☐☑ |
Saccharomyces cerevisiae | FOX2 | 5 of 9 | Yes | Yes | ☑ ☑☐☐☐☑☐☑☑ |
Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
---|---|---|---|---|---|---|
dhs-15 | 1 | 342 | 42 | 26 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
cror-2 | 2 | 336 | 41 | 27 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
F28H7.2 | 3 | 349 | 41 | 24 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
D1054.8 | 4 | 329 | 40 | 24 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
dhs-25 | 5 | 254 | 50 | 33 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
dhsl-4 | 6 | 316 | 41 | 24 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
C06E4.3 | 7 | 312 | 41 | 25 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
F02C12.2 | 8 | 309 | 41 | 24 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
let-767 | 9 | 342 | 35 | 24 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
F26D2.15 | 10 | 315 | 42 | 22 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
W03F9.9 | 11 | 281 | 44 | 25 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
C06E4.6 | 12 | 275 | 45 | 25 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
ZK829.1 | 13 | 256 | 46 | 28 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
dhs-11 | 14 | 257 | 46 | 28 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
stdh-1 | 15 | 305 | 37 | 25 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
dhs-4 | 16 | 247 | 47 | 28 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
F25D1.5 | 17 | 249 | 45 | 27 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
T01G6.1 | 18 | 251 | 44 | 26 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
dhs-23 | 19 | 257 | 43 | 25 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
dhs-3 | 20 | 233 | 48 | 27 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
ard-1 | 21 | 226 | 47 | 28 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
dhs-14 | 22 | 209 | 50 | 30 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
cror-1 | 23 | 210 | 50 | 28 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
maoc-1 | 24 | 233 | 39 | 23 | 3 of 8 | ☐ ☐☐☑☐☐☑☑ |
stdh-4 | 25 | 245 | 40 | 27 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
dhs-19 | 26 | 199 | 49 | 31 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
stdh-2 | 27 | 212 | 43 | 26 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
dhs-27 | 28 | 191 | 47 | 30 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
nta-1 | 29 | 204 | 46 | 25 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
stdh-3 | 30 | 205 | 42 | 25 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
Phenotype Term | Annotation details | References |
---|---|---|
ascaroside biosynthesis variant | ||
dauer pheromone production defective | ||
developmental timing variant | ||
fat associated bodies increased | ||
fat content variant | ||
larval arrest | ||
lipid composition variant | ||
lipid hydrolysis regulation variant | ||
organism starvation response variant | ||
protein subcellular localization variant |
all annotations | all disease by infectious agent | bacterial infectious disease | fungal infectious disease | parasitic infectious disease | viral infectious disease | all disease of anatomical entity | cardiovascular system disease | central nervous system disease | endocrine system disease | gastrointestinal system disease | hematopoietic system disease | immune system disease | integumentary system disease | musculoskeletal system disease | peripheral nervous system disease | reproductive system disease | respiratory system disease | sensory system disease | thoracic disease | urinary system disease | all disease of cellular proliferation | benign neoplasm | cancer | pre-malignant neoplasm | all genetic disease | chromosomal disease | monogenic disease | polygenic disease | all other disease | disease of mental health | disease of metabolism | physical disorder | syndrome | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
dhs-28 (Cel) | |||||||||||||||||||||||||||||||||||||||
HSD17B4 (Hsa) | |||||||||||||||||||||||||||||||||||||||
Hsd17b4 (Mmu) | |||||||||||||||||||||||||||||||||||||||
Hsd17b4 (Rno) | |||||||||||||||||||||||||||||||||||||||
hsd17b4 (Xtr) | |||||||||||||||||||||||||||||||||||||||
Species | Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
---|---|---|---|---|---|---|---|---|
Caenorhabditis elegans | dhs-28 | is implicated in | obesity |
| ||||
Homo sapiens | HSD17B4 | is implicated in | D-bifunctional protein deficiency |
| ||||
Homo sapiens | HSD17B4 | is implicated in |
| D-bifunctional protein deficiency |
| |||
Homo sapiens | HSD17B4 | is implicated in | Perrault syndrome |
| ||||
Homo sapiens | HSD17B4 | is implicated in | Stiff-Person syndrome |
| ||||
Rattus norvegicus | Hsd17b4 | is marker for | hypertension |
| ||||
Mus musculus | Hsd17b4 | is implicated in | D-bifunctional protein deficiency |
| ||||
Saccharomyces cerevisiae | FOX2 | is implicated in | lipid metabolism disorder |
|
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
hj8 | allele | Yes | Yes | ||||
hj5 | allele with one associated variant | point mutation
| Yes | ||||
hj6 | allele with one associated variant | point mutation
| Yes | ||||
tm2581 | allele with one associated variant | deletion
| Yes | ||||
hj7 | allele with one associated variant | point mutation
| Yes | ||||
NC_003284.9:g.6818886C>T | variant | SNP
| |||||
NC_003284.9:g.6819029T>A | variant | SNP
| |||||
NC_003284.9:g.6818803G>A | variant | SNP
| |||||
NC_003284.9:g.6819879A>C | variant | SNP
| |||||
NC_003284.9:g.6819918G>A | variant | SNP
|
dhs-28 molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
---|---|---|---|---|---|---|
protein | atx-2 | Caenorhabditis elegans | protein |
| PMID:27457958 | |
protein | ccar-1 | Caenorhabditis elegans | protein |
| PMID:38126797 | |
protein | dhs-28 | Caenorhabditis elegans | protein |
| PMID:23313254 | |
protein | dlg-1 | Caenorhabditis elegans | protein |
| PMID:27506200 | |
protein | glh-1 | Caenorhabditis elegans | protein |
| PMID:31506335 | |
protein | glh-1 | Caenorhabditis elegans | protein |
| PMID:32245789 | |
protein | gras-1 | Caenorhabditis elegans | protein |
| PMID:36809245 | |
protein | hsp-16.2 | Caenorhabditis elegans | protein |
| PMID:26009280 | |
protein | hsp-16.2 | Caenorhabditis elegans | protein |
| PMID:26009280 | |
protein | lin-53 | Caenorhabditis elegans | protein |
| PMID:31397537 |
dhs-28 role | dhs-28 genetic perturbation | Interactor gene | Interactor species | Interactor role | Interactor genetic perturbation | Interaction type | Phenotype or trait | Source | Reference |
---|---|---|---|---|---|---|---|---|---|
suppressor gene | clk-1 | Caenorhabditis elegans | suppressed gene | qm30 | genetic suppression (partial) | PMID:22438816 |