Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: cellular component organization Molecular Function: carbohydrate derivative binding
ATM
(Homo sapiens)Gene
Name: ATM serine/threonine kinase
Synonyms: serine/threonine kinase ATM, TEL1, telomere maintenance 1, homolog, MGC74674, human phosphatidylinositol 3-kinase homolog, ATDC, truncated ATM serine/threonine kinase, DKFZp781A0353, ATA, AT mutated, ATC, ataxia telangiectasia mutated, ATD, TEL1, ataxia telangiectasia mutated (includes complementation groups A, C and D), ATE, A-T mutated, serine-protein kinase ATM, TELO1, AT1
Source: HGNC:795
Biotype: protein coding gene
ACT1
(Saccharomyces cerevisiae)Gene
Name: ACTin
Synonyms: ABY1, END7, YFL039C
Source: SGD:S000001855
Biotype: protein coding gene
wg
(Drosophila melanogaster)Gene
Name: wingless
Synonyms: fg, flag, Wingless, I, wingless, Dint-1, l(2)rO727, D.int-1, WG, lethal (2) SH1281, l(2)SH1281, l(2)wg, Dwnt-1, dWnt, Glazed, Sternopleural, Wnt, WNT, wgl, Wnt1, glazed, wnt1, spd, Complementation group I, int-1, spade, Dm-1, Wg, Br, Dm Wg, DWint-1, Bristled, DWnt-1, l(2)SH2 1281, l(2)02657, wnt, Wnt-1, CG4889, Sp, Gla
Source: FB:FBgn0284084
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
CDC28
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: YBR160W, SRM5, HSL5, CDK1
Source: SGD:S000000364
Biotype: protein coding gene
BRAF
(Homo sapiens)Gene
Name: B-Raf proto-oncogene, serine/threonine kinase
Synonyms: serine/threonine-protein kinase B-raf, RAFB1, B-Raf serine/threonine-protein, B-RAF1, v-raf murine sarcoma viral oncogene homolog B1, v-raf murine sarcoma viral oncogene homolog B, p94, B-Raf proto-oncogene serine/threonine-protein kinase (p94), proto-oncogene B-Raf, MGC138284, MGC126806, NS7, B-raf, BRAF1, FLJ95109, 94 kDa B-raf protein, BRAF-1, murine sarcoma viral (v-raf) oncogene homolog B1
Source: HGNC:1097
Biotype: protein coding gene
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide(1-42), beta-amyloid peptide, preA4, beta-amyloid peptide(1-40), cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, alpha-sAPP, AD1, alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), protease nexin-II, CTFgamma, amyloid beta A4 protein, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
EGFR
(Homo sapiens)Gene
Name: epidermal growth factor receptor
Synonyms: PIG61, NNCIS, receptor tyrosine-protein kinase erbB-1, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), erythroblastic leukemia viral (v-erb-b) oncogene homolog, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, NISBD2, HER1
Source: HGNC:3236
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, MGC1571, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2
Source: HGNC:613
Biotype: protein coding gene
CFTR
(Homo sapiens)Gene
Name: CF transmembrane conductance regulator
Synonyms: CF, ABCC7, cystic fibrosis transmembrane conductance regulator, atp-binding cassette (sub-family c, member 7), MRP7, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7, dJ760C5.1, ATP-binding cassette sub-family C member 7, ABC35, cystic fibrosis transmembrane conductance regulator, TNR-CFTR, cystic fibrosis transmembrane conductance regulating, channel conductance-controlling ATPase, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Source: HGNC:1884
Biotype: protein coding gene
PMA1
(Saccharomyces cerevisiae)Gene
Name: Plasma Membrane ATPase
Synonyms: YGL008C, KTI10
Source: SGD:S000002976
Biotype: protein coding gene
dpp
(Drosophila melanogaster)Gene
Name: decapentaplegic
Synonyms: shv, DPP, Dpp, ho, TGF-b, blink, M(2)23AB, DmDPP, l(2)10638, M(2)LS1, Decapentaplegic/Bone Morphogenetic Protein, Haplo-insufficient, TGF-beta, Tg, CG9885, DPP-C, TGFbeta, blk, Tegula, Hin-d, Bmp, BMP, Decapentaplegic, bone morphogenetic protein, l(2)22Fa, Tgfbeta, heldout, Dpp/TGFbeta, bone morphogenic protein, shortvein, l(2)k17036, Dm-DPP
Source: FB:FBgn0000490
Biotype: protein coding gene
Kit
(Mus musculus)Gene
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: Dominant white spotting, gsf spotted coat 1, Fdc, c-KIT, Gsfsco1, dominant spotting, Ssm, gsf spotted coat 5, SCO5, Bs, SCO1, Tr-kit, W, CD117, spotted sterile male, Steel Factor Receptor, Gsfsow3, Gsfsco5, phenotype like Sl or W 3, belly-spot, SOW3
Source: MGI:96677
Biotype: protein coding gene
Mpo
(Mus musculus)Gene
Name: myeloperoxidase
Synonyms: Not Available
Source: MGI:97137
Biotype: protein coding gene
KRAS
(Homo sapiens)Gene
Name: KRAS proto-oncogene, GTPase
Synonyms: KI-RAS, RALD, NS, c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, PR310 c-K-ras oncogene, KRAS-ENOPH fusion, K-RAS2B, GTPase KRas, K-RAS2A, NS3, K-RAS4B, K-RAS4A, c-Kirsten-ras protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, Kirsten rat sarcoma viral proto-oncogene, c-Ki-ras, Kirsten rat sarcoma viral oncogene homolog, oncogene KRAS2, K-ras p21 protein, RASK2, CFC2, K-Ras, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, C-K-RAS, K-Ras 2, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, OES, cellular transforming proto-oncogene, KRAS2, 'C-K-RAS, proto-oncogene GTPase, transforming protein p21, KRAS1
Source: HGNC:6407
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, Alzheimer disease amyloid beta protein, cerebrovascular amyloid peptide, protease nexin II, expressed sequence AL024401, AL024401, RIKEN cDNA E030013M08 gene, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
FGFR3
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 3
Synonyms: tyrosine kinase JTK4, JTK4, HSFGFR3EX, ACH, CEK2, fibroblast growth factor receptor 3 variant 4, achondroplasia, thanatophoric dwarfism, CD333, fibroblast growth factor receptor 3-S, hydroxyaryl-protein kinase, FGFR-3
Source: HGNC:3690
Biotype: protein coding gene
Actb
(Mus musculus)Gene
Name: actin, beta
Synonyms: A-X actin-like protein, E430023M04Rik, RIKEN cDNA E430023M04 gene, Actx, melanoma X-actin, beta-actin
Source: MGI:87904
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: mechanistic target of rapamycin, rapamycin target protein 1, rapamycin and FKBP12 target 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FKBP12-rapamycin complex-associated protein 1, FRAP2, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, SKS, FRAP, serine/threonine-protein kinase mTOR, RAPT1, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
Braf
(Mus musculus)Gene
Name: Braf transforming gene
Synonyms: expressed sequence C87398, expressed sequence AA120551, expressed sequence AA387315, Braf-2, Braf2, AA387315, DNA segment, Chr 6, ERATO Doi 631, expressed, RIKEN cDNA 9930012E13 gene, C87398, AA120551, Braf transforming gene 2, D6Ertd631e, expressed sequence AA473386, AA473386, 9930012E13Rik
Source: MGI:88190
Biotype: protein coding gene
ANOS1
(Homo sapiens)Gene
Name: anosmin 1
Synonyms: HHA, ADMLX, adhesion molecule-like X-linked, kallmann syndrome protein, Kallmann syndrome-1 sequence (anosmin-1), WAP four-disulfide core domain 19, HH1, KMS, Kallmann syndrome interval gene 1, anosmin-1, Kallmann syndrome 1 sequence, KALIG-1, KAL, KAL1, WFDC19
Source: HGNC:6211
Biotype: protein coding gene
CLPB
(Homo sapiens)Gene
Name: ClpB family mitochondrial disaggregase
Synonyms: MGCA7, SKD3, ANKCLB, ankyrin-repeat containing bacterial clp fusion, ClpB homolog, mitochondrial AAA ATPase chaperonin, caseinolytic peptidase B protein homolog, testicular secretory protein Li 11, MEGCANN, MGCA7A, suppressor of potassium transport defect 3, ANKCLP, mitochondrial disaggregase, FLJ13152, caseinolytic mitochondrial matrix peptidase chaperone subunit B, HSP78, ClpB caseinolytic peptidase B homolog, SCN9
Source: HGNC:30664
Biotype: protein coding gene
RECQL
(Homo sapiens)Gene
Name: RecQ like helicase
Synonyms: RecQ protein-like (DNA helicase Q1-like), RecQ1, recQ protein-like 1, DNA helicase, RecQ-like type 1, ATP-dependent DNA helicase Q1, DNA helicase Q1-like, RECON, DNA 3'-5' helicase Q1, DNA-dependent ATPase Q1, RecQ helicase-like, RECQL1
Source: HGNC:9948
Biotype: protein coding gene
ACTB
(Homo sapiens)Gene
Name: actin beta
Synonyms: actin, cytoplasmic 1, DDS1, beta cytoskeletal actin, actin, beta, CSMH, PS1TP5BP1, BNS, PS1TP5-binding protein 1, BKRNS, I(2)-actin, BRWS1, THC8
Source: HGNC:132
Biotype: protein coding gene
myo-3
(Caenorhabditis elegans)Gene
Name: MYOsin heavy chain structural genes 3
Synonyms: CELE_K12F2.1, K12F2.1, sup-3
Source: WB:WBGene00003515
Biotype: protein coding gene
VCP
(Homo sapiens)Gene
Name: valosin containing protein
Synonyms: epididymis secretory protein Li 70, IBMPFD, valosin-containing protein, HEL-S-70, MGC148092, CMT2Y, TERA, FTDALS6, transitional endoplasmic reticulum ATPase, yeast Cdc48p homolog, p97, 15S Mg(2+)-ATPase p97 subunit, HEL-220, MGC8560, TER ATPase, CDC48, MGC131997, ALS14, IBMPFD1, epididymis luminal protein 220
Source: HGNC:12666
Biotype: protein coding gene
HSPA1A
(Homo sapiens)Gene
Name: heat shock protein family A (Hsp70) member 1A
Synonyms: HSP70-2, HSP70-1, epididymis secretory protein Li 103, HSP70-1A, FLJ54303, FLJ75127, FLJ54408, heat shock 70kD protein 1A, heat shock 70 kDa protein 1/2, HSP70.1/HSP70.2, HSP70I, heat shock-induced protein, HSP72, dnaK-type molecular chaperone HSP70-1, HSP70.2, HSP70.1, HSP70, heat shock 70 kDa protein 1A, Heat shock 70 kDa protein 1B, HEL-S-103, HSPA1, heat shock 70kDa protein 1A, HSP70-1/HSP70-2, Heat shock 70 kDa protein 2, heat shock 70 kDa protein 1A/1B, heat shock 70 kDa protein 1, FLJ54392, FLJ54370, heat shock protein family A member 1A, HSPA1B
Source: HGNC:5232
Biotype: protein coding gene
SGS1
(Saccharomyces cerevisiae)Gene
Name: Slow Growth Suppressor
Synonyms: YMR190C
Source: SGD:S000004802
Biotype: protein coding gene
CHEK2
(Homo sapiens)Gene
Name: checkpoint kinase 2
Synonyms: CDS1, HuCds1, PP1425, serine/threonine-protein kinase Chk2, checkpoint-like protein CHK2, TPDS4, CHK2 checkpoint homolog, cds1 homolog, RAD53, truncated checkpoint kinase 2, CHK2, LFS2, hCds1
Source: HGNC:16627
Biotype: protein coding gene
Cftr
(Mus musculus)Gene
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7, expressed sequence AW495489, AW495489, RGD1561193
Source: MGI:88388
Biotype: protein coding gene
TSSK2
(Homo sapiens)Gene
Name: testis specific serine kinase 2
Synonyms: TSK2, SPOGA2, serine/threonine kinase 22B (spermiogenesis associated), testis-specific serine/threonine-protein kinase 2, testis-specific kinase 2, testicular secretory protein Li 61, serine/threonine-protein kinase 22B, testis-specific serine kinase 2, spermiogenesis associated 2, TSSK-2, testis specific serine threonine kinase 2, FLJ38613, DGS-G, diGeorge syndrome protein G, TSK-2, STK22B
Source: HGNC:11401
Biotype: protein coding gene
ABCB1
(Homo sapiens)Gene
Name: ATP binding cassette subfamily B member 1
Synonyms: P-GP, ATP-binding cassette, sub-family B (MDR/TAP), member 1, CLCS, ATP-binding cassette sub-family B member 1, ENPAT, PGY1, multidrug resistance protein 1, ATP-binding cassette, subfamily B, member 1, GP170, colchicin sensitivity, ATP-dependent translocase ABCB1, p-170, MDR1, ABC20, MGC163296, P-glycoprotein 1, P glycoprotein, phospholipid transporter ABCB1, doxorubicin resistance, CD243
Source: HGNC:40
Biotype: protein coding gene
SNF1
(Saccharomyces cerevisiae)Gene
Name: Sucrose NonFermenting
Synonyms: CCR1, PAS14, CAT1, GLC2, HAF3, YDR477W
Source: SGD:S000002885
Biotype: protein coding gene
plk-1
(Caenorhabditis elegans)Gene
Name: POLO Kinase 1
Synonyms: CELE_C14B9.4, C14B9.4, plc1
Source: WB:WBGene00004042
Biotype: protein coding gene
Fgfr3
(Mus musculus)Gene
Name: fibroblast growth factor receptor 3
Synonyms: sam3, HBGFR, Fgfr-3
Source: MGI:95524
Biotype: protein coding gene
SSA1
(Saccharomyces cerevisiae)Gene
Name: Stress-Seventy subfamily A
Synonyms: YG100, YAL005C
Source: SGD:S000000004
Biotype: protein coding gene
Fn1
(Mus musculus)Gene
Name: fibronectin 1
Synonyms: Fn, FIBNEC, fn-1, Fn-1
Source: MGI:95566
Biotype: protein coding gene
Pkm
(Mus musculus)Gene
Name: pyruvate kinase, muscle
Synonyms: AL024370, Pk-3, Pkm2, Pk-2, AL024424, pyruvate kinase 3, AA414905, expressed sequence AA414905, expressed sequence AL024370, pyruvate kinase, expressed sequence AL024424, Pk3, PKM12, PK
Source: MGI:97591
Biotype: protein coding gene
Cit
(Rattus norvegicus)Gene
Name: citron rho-interacting serine/threonine kinase
Synonyms: LOC288698, postsynaptic density protein (citron), citron kinase, citron Rho-interacting kinase, citron (rho-interacting, serine/threonine kinase 21), rho-interacting, serine/threonine-protein kinase 21, citron-K, CRIK, citron, citron-K kinase
Source: RGD:70878
Biotype: protein coding gene
NLRP3
(Homo sapiens)Gene
Name: NLR family pyrin domain containing 3
Synonyms: caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, cryopyrin, NACHT, LRR and PYD domains - containing protein 3, CIAS1, deafness, autosomal dominant 34, NACHT, LRR and PYD domains-containing protein 3, cold autoinflammatory syndrome 1, FCAS, cryopyrin, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, AII/AVP receptor-like, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3, FCAS1, AGTAVPRL, DFNA34, AII, CLR1.1, MWS, PYPAF1, AII/AVP, NACHT, LRR and PYD containing protein 3, NLR family, pyrin domain containing 3, FLJ95925, NALP3, C1orf7, angiotensin/vasopressin receptor AII/AVP-like, FCU, AVP, KEFH
Source: HGNC:16400
Biotype: protein coding gene
YPT1
(Saccharomyces cerevisiae)Gene
Name: Yeast Protein Two
Synonyms: YP2, YFL038C
Source: SGD:S000001856
Biotype: protein coding gene
Adck1
(Mus musculus)Gene
Name: aarF domain containing kinase 1
Synonyms: 2610005A10Rik, RIKEN cDNA 2610005A10 gene
Source: MGI:1919363
Biotype: protein coding gene
Arl13b
(Mus musculus)Gene
Name: ADP-ribosylation factor-like 13B
Synonyms: A930014M17Rik, A530097K21Rik, hennin, hnn, C530009C10Rik, RIKEN cDNA A530097K21 gene, ADP-ribosylation factor-like 2-like 1, RIKEN cDNA A930014M17 gene, Arl2l1, RIKEN cDNA C530009C10 gene
Source: MGI:1915396
Biotype: protein coding gene
ERCC2
(Homo sapiens)Gene
Name: ERCC excision repair 2, TFIIH core complex helicase subunit
Synonyms: general transcription and DNA repair factor IIH helicase subunit XPD, TTD, TFIIH basal transcription factor complex 80 kDa subunit, TTD1, TFIIH basal transcription factor complex helicase subunit, COFS2, DNA 5'-3' helicase XPD, XPD, EM9, excision repair cross-complementing rodent repair deficiency, complementation group 2, xeroderma pigmentosum complementary group D, xeroderma pigmentosum group D-complementing protein, BTF2 p80, basic transcription factor 2 80 kDa subunit, trichothiodystrophy, MGC102762, MGC126218, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex helicase XPB subunit, MGC126219, excision repair cross-complementation group 2, TFIIH basal transcription factor complex helicase XPD subunit, TFIIH subunit XPD, TFIIH, CXPD, TFIIH p80, TFIIH 80 kDa subunit, DNA excision repair protein ERCC-2
Source: HGNC:3434
Biotype: protein coding gene
MGM1
(Saccharomyces cerevisiae)Gene
Name: Mitochondrial Genome Maintenance
Synonyms: MNA1, YOR211C
Source: SGD:S000005737
Biotype: protein coding gene
Kras
(Mus musculus)Gene
Name: Kirsten rat sarcoma viral oncogene homolog
Synonyms: Kras-2, expressed sequence AI929937, K-ras, AI929937, c-Ki-ras, Ki-ras, Kirsten rat sarcoma oncogene 2, expressed, p21, Kras2
Source: MGI:96680
Biotype: protein coding gene
Nrp1
(Mus musculus)Gene
Name: neuropilin 1
Synonyms: Npn1, NPN-1, Neuropilin-1, NP-1, Nrp
Source: MGI:106206
Biotype: protein coding gene
ATR
(Homo sapiens)Gene
Name: ATR serine/threonine kinase
Synonyms: FRAP-related protein 1, MEC1, ataxia telangiectasia and Rad3-related protein, MEC1, mitosis entry checkpoint 1, homolog, ataxia telangiectasia and Rad3 related, FRAP-related protein-1, FRP1, SCKL1, serine/threonine-protein kinase ATR, protein kinase ATR, SCKL, Rad3 related protein, FCTCS
Source: HGNC:882
Biotype: protein coding gene
Ulk4
(Mus musculus)Gene
Name: unc-51-like kinase 4
Synonyms: RIKEN cDNA 4932415A06 gene, 4932415A06Rik, RGD1565726
Source: MGI:1921622
Biotype: protein coding gene