Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: cellular component organization Molecular Function: small molecule binding
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
ACE2
(Homo sapiens)Gene
Name: angiotensin converting enzyme 2
Synonyms: peptidyl-dipeptidase A, metalloprotease MPROT15, angiotensin I converting enzyme 2, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, truncated angiotensin converting enzyme 2, angiotensin-converting enzyme homolog, angiotensin-converting enzyme 2, ACEH, ACE-related carboxypeptidase, DKFZp434A014, angiotensin-converting enzyme-related carboxypeptidase
Source: HGNC:13557
Biotype: protein coding gene
ATM
(Homo sapiens)Gene
Name: ATM serine/threonine kinase
Synonyms: serine/threonine kinase ATM, TEL1, telomere maintenance 1, homolog, MGC74674, human phosphatidylinositol 3-kinase homolog, ATDC, truncated ATM serine/threonine kinase, DKFZp781A0353, ATA, AT mutated, ATC, ataxia telangiectasia mutated, ATD, TEL1, ataxia telangiectasia mutated (includes complementation groups A, C and D), ATE, A-T mutated, serine-protein kinase ATM, TELO1, AT1
Source: HGNC:795
Biotype: protein coding gene
BRCA1
(Homo sapiens)Gene
Name: BRCA1 DNA repair associated
Synonyms: RNF53, early onset breast cancer 1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast cancer 1, BRCC1, BRCA1, DNA repair associated, RING finger protein 53, breast and ovarian cancer susceptibility protein 1, BRCA1/BRCA2-containing complex, subunit 1, breast cancer 1, early onset, IRIS, Fanconi anemia, complementation group S, breast cancer type 1 susceptibility protein, BRCAI, PNCA4, PSCP, truncated BRCA1, BROVCA1, protein phosphatase 1, regulatory subunit 53, breast cancer 1, PPP1R53, FANCS
Source: HGNC:1100
Biotype: protein coding gene
ACT1
(Saccharomyces cerevisiae)Gene
Name: ACTin
Synonyms: ABY1, END7, YFL039C
Source: SGD:S000001855
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
CDC28
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: YBR160W, SRM5, HSL5, CDK1
Source: SGD:S000000364
Biotype: protein coding gene
BRAF
(Homo sapiens)Gene
Name: B-Raf proto-oncogene, serine/threonine kinase
Synonyms: serine/threonine-protein kinase B-raf, RAFB1, B-Raf serine/threonine-protein, B-RAF1, v-raf murine sarcoma viral oncogene homolog B1, v-raf murine sarcoma viral oncogene homolog B, p94, B-Raf proto-oncogene serine/threonine-protein kinase (p94), proto-oncogene B-Raf, MGC138284, MGC126806, NS7, B-raf, BRAF1, FLJ95109, 94 kDa B-raf protein, BRAF-1, murine sarcoma viral (v-raf) oncogene homolog B1
Source: HGNC:1097
Biotype: protein coding gene
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide(1-42), beta-amyloid peptide, preA4, beta-amyloid peptide(1-40), cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, alpha-sAPP, AD1, alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), protease nexin-II, CTFgamma, amyloid beta A4 protein, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
EGFR
(Homo sapiens)Gene
Name: epidermal growth factor receptor
Synonyms: PIG61, NNCIS, receptor tyrosine-protein kinase erbB-1, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), erythroblastic leukemia viral (v-erb-b) oncogene homolog, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, NISBD2, HER1
Source: HGNC:3236
Biotype: protein coding gene
HLA-A
(Homo sapiens)Gene
Name: major histocompatibility complex, class I, A
Synonyms: HLA class I histocompatibility antigen, A-1 alpha chain, HLA A, HLAA, MHC class I antigen A*34, MHC class I antigen A*33, HLA class I histocompatibility antigen, A-43 alpha chain, MHC class I antigen A*32, MHC class I antigen A*31, HLA-A11, MHC class II antigen, HLA class I histocompatibility antigen, A-80 alpha chain, MHC class I antigen A*36, HLA class I histocompatibility antigen, A-23 alpha chain, HLA class I histocompatibility antigen, A-66 alpha chain, HLA class I histocompatibility antigen, A-9 alpha chain, aw-19, MHC class I antigen HLA-A33, truncated MHC class I antigen, MHC class I antigen A*30, MHC class I antigen A*74, MHC class I antigen A*1, leucocyte antigen A, HLA-Aw33.1, MHC class I antigen A*43, MHC class I anti, MHC class I antigen HLA-A heavy chain, HLA class I histocompatibility antigen, A-69 alpha chain-like, HLA class I histocompatibility antigen, A-26 alpha chain, HLA class I histocompatibility antigen, A-36 alpha chain, MHC class I antigen A*80, HLA class I histocompatibility antigen, A-28 alpha chain, aw-24, HLA class I histocompatibility antigen, A-24 alpha chain, HLA class I histocompatibility antigen, A-25 alpha chain, HLA class I histocompatibility antigen, A-29 alpha chain, aw-66, LOC100507703, leucocyte antigen class I, HLA-DQB1, MHC class I antigene, antigen presenting molecule, HLA class I antigen, FLJ26655, HLA class I histocompatibility antigen, A-31 alpha chain, MHC leukocyte antigen, HLA class I histocompatibility antigen, A-10 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, MHC class I antigen A*11, HLA-A33, HLA class I histocompatibility antigen, A-34 alpha chain, Aw-69, HLA-A locus alpha 2 domain, Aw-68, aw-34, leukocyte antigen class I-A, aw-36, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, MHC class I antigen heavy chain, MHC class I antigen A*29, aw-80, MHC class I antigen A*2, MCH class I antigen, MHC class I antigen A*3, MHC class I antigen A*23, HLA-A null, MHC class I antigen A*66, MHC class I antigen A*26, MHC class I antigen A*69, MHC class I antigen A*25, MHC class I antigen A*24, MHC class I antigen A*68, MHC classI antigen, HLA locus, HLA class I histocompatibility antigen, A alpha chain, MHC Class I antigen, MHC class 1 antigen, aw-43, Aw-33, Aw-74, HLA-DRB1
Source: HGNC:4931
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, MGC1571, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2
Source: HGNC:613
Biotype: protein coding gene
CFTR
(Homo sapiens)Gene
Name: CF transmembrane conductance regulator
Synonyms: CF, ABCC7, cystic fibrosis transmembrane conductance regulator, atp-binding cassette (sub-family c, member 7), MRP7, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7, dJ760C5.1, ATP-binding cassette sub-family C member 7, ABC35, cystic fibrosis transmembrane conductance regulator, TNR-CFTR, cystic fibrosis transmembrane conductance regulating, channel conductance-controlling ATPase, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Source: HGNC:1884
Biotype: protein coding gene
PMA1
(Saccharomyces cerevisiae)Gene
Name: Plasma Membrane ATPase
Synonyms: YGL008C, KTI10
Source: SGD:S000002976
Biotype: protein coding gene
Kit
(Mus musculus)Gene
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: Dominant white spotting, gsf spotted coat 1, Fdc, c-KIT, Gsfsco1, dominant spotting, Ssm, gsf spotted coat 5, SCO5, Bs, SCO1, Tr-kit, W, CD117, spotted sterile male, Steel Factor Receptor, Gsfsow3, Gsfsco5, phenotype like Sl or W 3, belly-spot, SOW3
Source: MGI:96677
Biotype: protein coding gene
Gapdh
(Mus musculus)Gene
Name: glyceraldehyde-3-phosphate dehydrogenase
Synonyms: cDNA sequence AK190093, BARS-38, AK190093, Gapd
Source: MGI:95640
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
Mpo
(Mus musculus)Gene
Name: myeloperoxidase
Synonyms: Not Available
Source: MGI:97137
Biotype: protein coding gene
RAD27
(Saccharomyces cerevisiae)Gene
Name: RADiation sensitive
Synonyms: FEN1, ERC11, YKL113C, RTH1
Source: SGD:S000001596
Biotype: protein coding gene
KRAS
(Homo sapiens)Gene
Name: KRAS proto-oncogene, GTPase
Synonyms: KI-RAS, RALD, NS, c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, PR310 c-K-ras oncogene, KRAS-ENOPH fusion, K-RAS2B, GTPase KRas, K-RAS2A, NS3, K-RAS4B, K-RAS4A, c-Kirsten-ras protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, Kirsten rat sarcoma viral proto-oncogene, c-Ki-ras, Kirsten rat sarcoma viral oncogene homolog, oncogene KRAS2, K-ras p21 protein, RASK2, CFC2, K-Ras, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, C-K-RAS, K-Ras 2, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, OES, cellular transforming proto-oncogene, KRAS2, 'C-K-RAS, proto-oncogene GTPase, transforming protein p21, KRAS1
Source: HGNC:6407
Biotype: protein coding gene
DMD
(Homo sapiens)Gene
Name: dystrophin
Synonyms: truncated dystrophin, DXS270, mutant dystrophin, dystrophin (muscular dystrophy, Duchenne and Becker types), DXS272, mental retardation, X-linked 85, DXS239, DXS206, MRX85, BMD, DXS142, DXS230, DXS164, DXS268, CMD3B, DXS269
Source: HGNC:2928
Biotype: protein coding gene
SIRT1
(Homo sapiens)Gene
Name: sirtuin 1
Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, regulatory protein SIR2 homolog 1, hSIRT1, hSIR2, sirtuin type 1, NAD-dependent deacetylase sirtuin-1
Source: HGNC:14929
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, Alzheimer disease amyloid beta protein, cerebrovascular amyloid peptide, protease nexin II, expressed sequence AL024401, AL024401, RIKEN cDNA E030013M08 gene, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
FGFR3
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 3
Synonyms: tyrosine kinase JTK4, JTK4, HSFGFR3EX, ACH, CEK2, fibroblast growth factor receptor 3 variant 4, achondroplasia, thanatophoric dwarfism, CD333, fibroblast growth factor receptor 3-S, hydroxyaryl-protein kinase, FGFR-3
Source: HGNC:3690
Biotype: protein coding gene
crb
(Drosophila melanogaster)Gene
Name: crumbs
Synonyms: Crbs, l(3)07207, CT19912, 0509/20, Crumbs, CG6383, 1384/04, Crb, CRB, crumb, crumbs, far, fat rhabdomere, l(3)S058104, DmCrb, l(3)S050920, lethal (3) 07207, l(3)j1B5, fat rhabdomeres
Source: FB:FBgn0259685
Biotype: protein coding gene
Dmd
(Mus musculus)Gene
Name: dystrophin, muscular dystrophy
Synonyms: mdx, X-linked muscular dystrophy, Duchenne muscular dystrophy, Dp71, DNADMD1, pke, pyruvate kinase expression, Dp427, dys
Source: MGI:94909
Biotype: protein coding gene
Actb
(Mus musculus)Gene
Name: actin, beta
Synonyms: A-X actin-like protein, E430023M04Rik, RIKEN cDNA E430023M04 gene, Actx, melanoma X-actin, beta-actin
Source: MGI:87904
Biotype: protein coding gene
SOD1
(Homo sapiens)Gene
Name: superoxide dismutase 1
Synonyms: Cu/Zn superoxide dismutase, ALS, SOD, superoxide dismutase [Cu-Zn], indophenoloxidase A, HEL-S-44, superoxide dismutase 1, soluble, epididymis secretory protein Li 44, SOD, soluble, STAHP, hSod1, superoxide dismutase, cystolic, superoxide dismutase, ALS1, IPOA, homodimer
Source: HGNC:11179
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: mechanistic target of rapamycin, rapamycin target protein 1, rapamycin and FKBP12 target 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FKBP12-rapamycin complex-associated protein 1, FRAP2, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, SKS, FRAP, serine/threonine-protein kinase mTOR, RAPT1, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
Braf
(Mus musculus)Gene
Name: Braf transforming gene
Synonyms: expressed sequence C87398, expressed sequence AA120551, expressed sequence AA387315, Braf-2, Braf2, AA387315, DNA segment, Chr 6, ERATO Doi 631, expressed, RIKEN cDNA 9930012E13 gene, C87398, AA120551, Braf transforming gene 2, D6Ertd631e, expressed sequence AA473386, AA473386, 9930012E13Rik
Source: MGI:88190
Biotype: protein coding gene
COL1A1
(Homo sapiens)Gene
Name: collagen type I alpha 1 chain
Synonyms: pro-alpha-1 collagen type 1, collagen type I alpha 1, EDSARTH1, collagen of skin, tendon and bone, alpha-1 chain, EDSC, alpha1(I) procollagen, type I procollagen alpha 1 chain, OI1, type I proalpha 1, OI3, OI2, OI4, collagen alpha-1(I) chain, CAFYD, collagen alpha-1(I) chain preproprotein, collagen alpha 1 chain type I, collagen, type I, alpha 1, alpha-1 type I collagen
Source: HGNC:2197
Biotype: protein coding gene
myo-3
(Caenorhabditis elegans)Gene
Name: MYOsin heavy chain structural genes 3
Synonyms: CELE_K12F2.1, K12F2.1, sup-3
Source: WB:WBGene00003515
Biotype: protein coding gene
Col1a1
(Mus musculus)Gene
Name: collagen, type I, alpha 1
Synonyms: Col1a-1, Moloney leukemia virus 13, Cola1, Cola-1, COLIA1, Mov-13
Source: MGI:88467
Biotype: protein coding gene
Cftr
(Mus musculus)Gene
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7, expressed sequence AW495489, AW495489, RGD1561193
Source: MGI:88388
Biotype: protein coding gene
TSSK2
(Homo sapiens)Gene
Name: testis specific serine kinase 2
Synonyms: TSK2, SPOGA2, serine/threonine kinase 22B (spermiogenesis associated), testis-specific serine/threonine-protein kinase 2, testis-specific kinase 2, testicular secretory protein Li 61, serine/threonine-protein kinase 22B, testis-specific serine kinase 2, spermiogenesis associated 2, TSSK-2, testis specific serine threonine kinase 2, FLJ38613, DGS-G, diGeorge syndrome protein G, TSK-2, STK22B
Source: HGNC:11401
Biotype: protein coding gene
shha
(Danio rerio)Gene
Name: sonic hedgehog signaling molecule a
Synonyms: shh, vertebrate hedgehog homolog, sonic you, sonic-you, vhh1, fc83d08, syu, wu:fc83d08
Source: ZFIN:ZDB-GENE-980526-166
Biotype: protein coding gene
N
(Drosophila melanogaster)Gene
Name: Notch
Synonyms: 16-178, 16-55, RICN, Abruptex, Chp, Co, EG:163A10.2, Confluens, split, anon-EST:Liang-1.12, Ax, dNotch, Nicd, Chopped, Notch, NOTCH, strawberry, clone 1.12, co, spl, shd, 1.1, nd, l(1)3Cb, NICD, CG3936, notchoid, n[fah], notch, fa, NECD, CT13012, EG:140G11.1, facet, l(1)Ax, l(1)N, swb
Source: FB:FBgn0004647
Biotype: protein coding gene
Rag2
(Mus musculus)Gene
Name: recombination activating gene 2
Synonyms: Rag-2
Source: MGI:97849
Biotype: protein coding gene
SGS1
(Saccharomyces cerevisiae)Gene
Name: Slow Growth Suppressor
Synonyms: YMR190C
Source: SGD:S000004802
Biotype: protein coding gene
Trf
(Mus musculus)Gene
Name: transferrin
Synonyms: hpx, hypotransferrinemia with hemochromatosis, HP, Tfn, AI266983, expressed sequence AI266983
Source: MGI:98821
Biotype: protein coding gene
Hprt1
(Mus musculus)Gene
Name: hypoxanthine phosphoribosyltransferase 1
Synonyms: Hgprtase, expressed sequence C81579, hypoxanthine guanine phosphoribosyl transferase, Hprt, C81579, hypoxanthine guanine phosphoribosyl transferase 1
Source: MGI:96217
Biotype: protein coding gene
Mmp2
(Mus musculus)Gene
Name: matrix metallopeptidase 2
Synonyms: GelA, MMP-2, collagenase IVA, basement membrane, 72 kDa, gelatinase A, Clg4a, 72kDa type IV collagenase, 72kDa gelatinase
Source: MGI:97009
Biotype: protein coding gene
SNF1
(Saccharomyces cerevisiae)Gene
Name: Sucrose NonFermenting
Synonyms: CCR1, PAS14, CAT1, GLC2, HAF3, YDR477W
Source: SGD:S000002885
Biotype: protein coding gene
SOD1
(Saccharomyces cerevisiae)Gene
Name: SuperOxide Dismutase
Synonyms: YJR104C, CRS4
Source: SGD:S000003865
Biotype: protein coding gene
Prkn
(Mus musculus)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkinson disease (autosomal recessive, juvenile) 2, parkin, Park2, Parkin, Park
Source: MGI:1355296
Biotype: protein coding gene
MTHFR
(Homo sapiens)Gene
Name: methylenetetrahydrofolate reductase
Synonyms: methylenetetrahydrofolate reductase (NAD(P)H), methylenetetrahydrofolate reductase (NADPH), 5,10-methylenetetrahydrofolate reductase (NADPH)
Source: HGNC:7436
Biotype: protein coding gene
Brca1
(Mus musculus)Gene
Name: breast cancer 1, early onset
Synonyms: BRCA-1
Source: MGI:104537
Biotype: protein coding gene
CLPB
(Homo sapiens)Gene
Name: ClpB family mitochondrial disaggregase
Synonyms: MGCA7, SKD3, ANKCLB, ankyrin-repeat containing bacterial clp fusion, ClpB homolog, mitochondrial AAA ATPase chaperonin, caseinolytic peptidase B protein homolog, testicular secretory protein Li 11, MEGCANN, MGCA7A, suppressor of potassium transport defect 3, ANKCLP, mitochondrial disaggregase, FLJ13152, caseinolytic mitochondrial matrix peptidase chaperone subunit B, HSP78, ClpB caseinolytic peptidase B homolog, SCN9
Source: HGNC:30664
Biotype: protein coding gene