Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: cellular component organization Subcellular Expression: chromosome
Sox9
(Rattus norvegicus)Gene
Name: SRY-box transcription factor 9
Synonyms: SRY-box containing gene 9, LOC363699, SRY (sex determining region Y)-box 9, SRY box 9, transcription factor SOX-9, LOC100361122, SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal), SRY
Source: RGD:620474
Biotype: protein coding gene
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Pten
(Mus musculus)Gene
Name: phosphatase and tensin homolog
Synonyms: B430203M17Rik, RIKEN cDNA B430203M17 gene, expressed sequence AI463227, RIKEN cDNA 2310035O07 gene, TEP1, Mmac, A130070J02Rik, MMAC1, AI463227, 2310035O07Rik, RIKEN cDNA A130070J02 gene
Source: MGI:109583
Biotype: protein coding gene
ACE2
(Homo sapiens)Gene
Name: angiotensin converting enzyme 2
Synonyms: peptidyl-dipeptidase A, metalloprotease MPROT15, angiotensin I converting enzyme 2, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, truncated angiotensin converting enzyme 2, angiotensin-converting enzyme homolog, angiotensin-converting enzyme 2, ACEH, ACE-related carboxypeptidase, DKFZp434A014, angiotensin-converting enzyme-related carboxypeptidase
Source: HGNC:13557
Biotype: protein coding gene
ATM
(Homo sapiens)Gene
Name: ATM serine/threonine kinase
Synonyms: serine/threonine kinase ATM, TEL1, telomere maintenance 1, homolog, MGC74674, human phosphatidylinositol 3-kinase homolog, ATDC, truncated ATM serine/threonine kinase, DKFZp781A0353, ATA, AT mutated, ATC, ataxia telangiectasia mutated, ATD, TEL1, ataxia telangiectasia mutated (includes complementation groups A, C and D), ATE, A-T mutated, serine-protein kinase ATM, TELO1, AT1
Source: HGNC:795
Biotype: protein coding gene
TNNT2
(Homo sapiens)Gene
Name: troponin T2, cardiac type
Synonyms: truncated cardiac troponin T, LVNC6, CMPD2, CMH2, troponin T, cardiac muscle, TnTC, cardiomyopathy, hypertrophic 2, RCM3, troponin T type 2 (cardiac), troponin t2, cardiac muscle troponin T, CMD1D, cTnT, troponin T2, cardiac, cardiomyopathy, dilated 1D (autosomal dominant), MGC3889
Source: HGNC:11949
Biotype: protein coding gene
BRCA1
(Homo sapiens)Gene
Name: BRCA1 DNA repair associated
Synonyms: RNF53, early onset breast cancer 1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast cancer 1, BRCC1, BRCA1, DNA repair associated, RING finger protein 53, breast and ovarian cancer susceptibility protein 1, BRCA1/BRCA2-containing complex, subunit 1, breast cancer 1, early onset, IRIS, Fanconi anemia, complementation group S, breast cancer type 1 susceptibility protein, BRCAI, PNCA4, PSCP, truncated BRCA1, BROVCA1, protein phosphatase 1, regulatory subunit 53, breast cancer 1, PPP1R53, FANCS
Source: HGNC:1100
Biotype: protein coding gene
FLNA
(Homo sapiens)Gene
Name: filamin A
Synonyms: OPD, FLN-A, filamin-1, FLN1, FLN, XMVD, filamin A, alpha, XLVD, actin binding protein 280, FG syndrome 2, alpha filamin, MNS, filamin 1, DKFZp434P031, FMD, CSBS, FGS2, endothelial actin-binding protein, non-muscle filamin, OPD2, OPD1, NHBP, alpha-filamin, FLJ43642, filamin-A, ABPX, ABP-280, CVD1
Source: HGNC:3754
Biotype: protein coding gene
pax2a
(Danio rerio)Gene
Name: paired box 2a
Synonyms: no isthmus, pax2.1, pax-b, cb378, pax[zf-b], pax2a1, Pax-2, noi, Pax2.1, paxb
Source: ZFIN:ZDB-GENE-990415-8
Biotype: protein coding gene
Pax6
(Mus musculus)Gene
Name: paired box 6
Synonyms: 1500038E17Rik, AEY11, RIKEN cDNA 1500038E17 gene, Pax-6, Sey, gsf abnormal eyes 11, Dey, Dickie's small eye, Gsfaey11, small eye
Source: MGI:97490
Biotype: protein coding gene
fgf8a
(Danio rerio)Gene
Name: fibroblast growth factor 8a
Synonyms: cb110, ace, id:ibd5031, wu:fb73a06, etID309886.13, acerebellar, fgf8, fgf-8
Source: ZFIN:ZDB-GENE-990415-72
Biotype: protein coding gene
htt
(Drosophila melanogaster)Gene
Name: huntingtin
Synonyms: Huntingtin, CG9995, Htt, HTT, dHtt, dhtt, HD, DmHtt
Source: FB:FBgn0027655
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
wg
(Drosophila melanogaster)Gene
Name: wingless
Synonyms: fg, flag, Wingless, I, wingless, Dint-1, l(2)rO727, D.int-1, WG, lethal (2) SH1281, l(2)SH1281, l(2)wg, Dwnt-1, dWnt, Glazed, Sternopleural, Wnt, WNT, wgl, Wnt1, glazed, wnt1, spd, Complementation group I, int-1, spade, Dm-1, Wg, Br, Dm Wg, DWint-1, Bristled, DWnt-1, l(2)SH2 1281, l(2)02657, wnt, Wnt-1, CG4889, Sp, Gla
Source: FB:FBgn0284084
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
CDC28
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: YBR160W, SRM5, HSL5, CDK1
Source: SGD:S000000364
Biotype: protein coding gene
BRAF
(Homo sapiens)Gene
Name: B-Raf proto-oncogene, serine/threonine kinase
Synonyms: serine/threonine-protein kinase B-raf, RAFB1, B-Raf serine/threonine-protein, B-RAF1, v-raf murine sarcoma viral oncogene homolog B1, v-raf murine sarcoma viral oncogene homolog B, p94, B-Raf proto-oncogene serine/threonine-protein kinase (p94), proto-oncogene B-Raf, MGC138284, MGC126806, NS7, B-raf, BRAF1, FLJ95109, 94 kDa B-raf protein, BRAF-1, murine sarcoma viral (v-raf) oncogene homolog B1
Source: HGNC:1097
Biotype: protein coding gene
THO1
(Saccharomyces cerevisiae)Gene
Name: suppressor of the Transcriptional defect of Hpr1 by Overexpression
Synonyms: YER063W
Source: SGD:S000000865
Biotype: protein coding gene
BRCA2
(Homo sapiens)Gene
Name: BRCA2 DNA repair associated
Synonyms: truncated breast and ovarian cancer susceptibility protein 2, DNA repair-associated BRCA2, FAD1, truncated DNA repair-associated BRCA2, BRCC2, GLM3, BRCA2, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 2, breast cancer type 2 susceptibility protein, breast cancer 2, early onset, breast cancer 2 tumor suppressor, breast and ovarian cancer susceptibility gene, early onset, PNCA2, truncated BRCA2 DNA repair associated, fanconi anemia group D1 protein, truncated breast cancer 2, FAD, mutant BRCA2, breast cancer susceptibility protein BRCA2, FANCB, FANCD, breast and ovarian cancer susceptibility protein 2, mutant DNA repair-associated protein 2, FANCD1, BROVCA2, XRCC11, breast cancer 2, FACD
Source: HGNC:1101
Biotype: protein coding gene
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide(1-42), beta-amyloid peptide, preA4, beta-amyloid peptide(1-40), cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, alpha-sAPP, AD1, alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), protease nexin-II, CTFgamma, amyloid beta A4 protein, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
POC1A
(Homo sapiens)Gene
Name: POC1 centriolar protein A
Synonyms: WD repeat-containing protein 51A, PIX2, proteome of centriole protein 1A, WD repeat domain 51A, MGC131902, WDR51A, POC1 centriolar protein homolog A, SOFT, DKFZp434C245
Source: HGNC:24488
Biotype: protein coding gene
PTEN
(Homo sapiens)Gene
Name: phosphatase and tensin homolog
Synonyms: MHAM, DEC, PTENepsilon, 10q23del, phosphatase and tensin-like protein, PTEN1, mitochondrial PTENalpha, GLM2, PTEN variant PTEN-K267Rfs*9, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, CWS1, mutated in multiple advanced cancers 1, MMAC1, PTEN variant PTEN-L247*, PTEN variant PTEN-R234Afs*11, mitochondrial phosphatase and tensin protein alpha, TEP1, PTENgama, inositol polyphosphate 3-phosphatase, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, BZS, PTENbeta, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MGC11227
Source: HGNC:9588
Biotype: protein coding gene
HTT
(Homo sapiens)Gene
Name: huntingtin
Synonyms: LOMARS, huntington disease protein, HD, IT15, huntington disease gene homolog
Source: HGNC:4851
Biotype: protein coding gene
EGFR
(Homo sapiens)Gene
Name: epidermal growth factor receptor
Synonyms: PIG61, NNCIS, receptor tyrosine-protein kinase erbB-1, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), erythroblastic leukemia viral (v-erb-b) oncogene homolog, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, NISBD2, HER1
Source: HGNC:3236
Biotype: protein coding gene
HLA-A
(Homo sapiens)Gene
Name: major histocompatibility complex, class I, A
Synonyms: HLA class I histocompatibility antigen, A-1 alpha chain, HLA A, HLAA, MHC class I antigen A*34, MHC class I antigen A*33, HLA class I histocompatibility antigen, A-43 alpha chain, MHC class I antigen A*32, MHC class I antigen A*31, HLA-A11, MHC class II antigen, HLA class I histocompatibility antigen, A-80 alpha chain, MHC class I antigen A*36, HLA class I histocompatibility antigen, A-23 alpha chain, HLA class I histocompatibility antigen, A-66 alpha chain, HLA class I histocompatibility antigen, A-9 alpha chain, aw-19, MHC class I antigen HLA-A33, truncated MHC class I antigen, MHC class I antigen A*30, MHC class I antigen A*74, MHC class I antigen A*1, leucocyte antigen A, HLA-Aw33.1, MHC class I antigen A*43, MHC class I anti, MHC class I antigen HLA-A heavy chain, HLA class I histocompatibility antigen, A-69 alpha chain-like, HLA class I histocompatibility antigen, A-26 alpha chain, HLA class I histocompatibility antigen, A-36 alpha chain, MHC class I antigen A*80, HLA class I histocompatibility antigen, A-28 alpha chain, aw-24, HLA class I histocompatibility antigen, A-24 alpha chain, HLA class I histocompatibility antigen, A-25 alpha chain, HLA class I histocompatibility antigen, A-29 alpha chain, aw-66, LOC100507703, leucocyte antigen class I, HLA-DQB1, MHC class I antigene, antigen presenting molecule, HLA class I antigen, FLJ26655, HLA class I histocompatibility antigen, A-31 alpha chain, MHC leukocyte antigen, HLA class I histocompatibility antigen, A-10 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, MHC class I antigen A*11, HLA-A33, HLA class I histocompatibility antigen, A-34 alpha chain, Aw-69, HLA-A locus alpha 2 domain, Aw-68, aw-34, leukocyte antigen class I-A, aw-36, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, MHC class I antigen heavy chain, MHC class I antigen A*29, aw-80, MHC class I antigen A*2, MCH class I antigen, MHC class I antigen A*3, MHC class I antigen A*23, HLA-A null, MHC class I antigen A*66, MHC class I antigen A*26, MHC class I antigen A*69, MHC class I antigen A*25, MHC class I antigen A*24, MHC class I antigen A*68, MHC classI antigen, HLA locus, HLA class I histocompatibility antigen, A alpha chain, MHC Class I antigen, MHC class 1 antigen, aw-43, Aw-33, Aw-74, HLA-DRB1
Source: HGNC:4931
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, MGC1571, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2
Source: HGNC:613
Biotype: protein coding gene
CFTR
(Homo sapiens)Gene
Name: CF transmembrane conductance regulator
Synonyms: CF, ABCC7, cystic fibrosis transmembrane conductance regulator, atp-binding cassette (sub-family c, member 7), MRP7, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7, dJ760C5.1, ATP-binding cassette sub-family C member 7, ABC35, cystic fibrosis transmembrane conductance regulator, TNR-CFTR, cystic fibrosis transmembrane conductance regulating, channel conductance-controlling ATPase, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Source: HGNC:1884
Biotype: protein coding gene
PMA1
(Saccharomyces cerevisiae)Gene
Name: Plasma Membrane ATPase
Synonyms: YGL008C, KTI10
Source: SGD:S000002976
Biotype: protein coding gene
dpp
(Drosophila melanogaster)Gene
Name: decapentaplegic
Synonyms: shv, DPP, Dpp, ho, TGF-b, blink, M(2)23AB, DmDPP, l(2)10638, M(2)LS1, Decapentaplegic/Bone Morphogenetic Protein, Haplo-insufficient, TGF-beta, Tg, CG9885, DPP-C, TGFbeta, blk, Tegula, Hin-d, Bmp, BMP, Decapentaplegic, bone morphogenetic protein, l(2)22Fa, Tgfbeta, heldout, Dpp/TGFbeta, bone morphogenic protein, shortvein, l(2)k17036, Dm-DPP
Source: FB:FBgn0000490
Biotype: protein coding gene
Kit
(Mus musculus)Gene
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: Dominant white spotting, gsf spotted coat 1, Fdc, c-KIT, Gsfsco1, dominant spotting, Ssm, gsf spotted coat 5, SCO5, Bs, SCO1, Tr-kit, W, CD117, spotted sterile male, Steel Factor Receptor, Gsfsow3, Gsfsco5, phenotype like Sl or W 3, belly-spot, SOW3
Source: MGI:96677
Biotype: protein coding gene
HTRA2
(Homo sapiens)Gene
Name: HtrA serine peptidase 2
Synonyms: serine proteinase OMI, PARK13, Omi stress-regulated endoprotease, protease, serine, 25, serine protease 25, high temperature requirement protein A2, OMI, PRSS25, serine protease HTRA2, mitochondrial, HtrA-like serine protease, MGCA8
Source: HGNC:14348
Biotype: protein coding gene
Gapdh
(Mus musculus)Gene
Name: glyceraldehyde-3-phosphate dehydrogenase
Synonyms: cDNA sequence AK190093, BARS-38, AK190093, Gapd
Source: MGI:95640
Biotype: protein coding gene
Flna
(Mus musculus)Gene
Name: filamin, alpha
Synonyms: dilated pupils 2, filamin 1, filamin-1, Dilp2, actin-binding protein 280, Fln1, GENA 379, RIKEN cDNA F730004A14 gene, F730004A14Rik, ABP-280, RGD1560614
Source: MGI:95556
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
Mpo
(Mus musculus)Gene
Name: myeloperoxidase
Synonyms: Not Available
Source: MGI:97137
Biotype: protein coding gene
RAD27
(Saccharomyces cerevisiae)Gene
Name: RADiation sensitive
Synonyms: FEN1, ERC11, YKL113C, RTH1
Source: SGD:S000001596
Biotype: protein coding gene
fgg
(Danio rerio)Gene
Name: fibrinogen gamma chain
Synonyms: zgc:56023, fb60h05, wu:fb62e01, fb62e01, wu:fb60h05
Source: ZFIN:ZDB-GENE-040426-1998
Biotype: protein coding gene
Htt
(Mus musculus)Gene
Name: huntingtin
Synonyms: C430023I11Rik, Huntington disease (human), expressed sequence AI256365, Huntington disease gene homolog, RIKEN cDNA C430023I11 gene, htt, Hd, HD, IT15, Hdh, AI256365
Source: MGI:96067
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, Alzheimer disease amyloid beta protein, cerebrovascular amyloid peptide, protease nexin II, expressed sequence AL024401, AL024401, RIKEN cDNA E030013M08 gene, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
PAX6
(Homo sapiens)Gene
Name: paired box 6
Synonyms: paired box 6 PAX6A-ASdel6-AS7 isoform, paired box homeotic gene-6, AN1, AN2, paired box 6 PAX6B-ASdel6 isoform, AN, paired box 6 PAX6A-del6 isoform, D11S812E, paired box protein Pax-6, MGDA, Aniridia 1, Aniridia 2, FVH1, paired box 6 PAX6-12a isoform, aniridia type II protein, oculorhombin, MGC17209, paired box 6 PAX6D isoform, ASGD5, WAGR, paired box 6 PAX6A-ASdel6 isoform, alternative protein PAX6
Source: HGNC:8620
Biotype: protein coding gene
Tardbp
(Mus musculus)Gene
Name: TAR DNA binding protein
Synonyms: Tdp43, 1190002A23Rik, expressed sequence C85084, TDP-43, Tdp-43, RIKEN cDNA 1190002A23 gene, C85084
Source: MGI:2387629
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
MYC
(Homo sapiens)Gene
Name: MYC proto-oncogene, bHLH transcription factor
Synonyms: proto-oncogene c-Myc, avian myelocytomatosis viral oncogene homolog, c-Myc, MYCC, v-myc myelocytomatosis viral oncogene homolog, myc proto-oncogene protein, class E basic helix-loop-helix protein 39, transcription factor p64, bHLHe39, MRTL, cMyc, myc-related translation/localization regulatory factor, v-myc avian myelocytomatosis viral oncogene homolog
Source: HGNC:7553
Biotype: protein coding gene
crb
(Drosophila melanogaster)Gene
Name: crumbs
Synonyms: Crbs, l(3)07207, CT19912, 0509/20, Crumbs, CG6383, 1384/04, Crb, CRB, crumb, crumbs, far, fat rhabdomere, l(3)S058104, DmCrb, l(3)S050920, lethal (3) 07207, l(3)j1B5, fat rhabdomeres
Source: FB:FBgn0259685
Biotype: protein coding gene
Dmd
(Mus musculus)Gene
Name: dystrophin, muscular dystrophy
Synonyms: mdx, X-linked muscular dystrophy, Duchenne muscular dystrophy, Dp71, DNADMD1, pke, pyruvate kinase expression, Dp427, dys
Source: MGI:94909
Biotype: protein coding gene
Actb
(Mus musculus)Gene
Name: actin, beta
Synonyms: A-X actin-like protein, E430023M04Rik, RIKEN cDNA E430023M04 gene, Actx, melanoma X-actin, beta-actin
Source: MGI:87904
Biotype: protein coding gene
Braf
(Mus musculus)Gene
Name: Braf transforming gene
Synonyms: expressed sequence C87398, expressed sequence AA120551, expressed sequence AA387315, Braf-2, Braf2, AA387315, DNA segment, Chr 6, ERATO Doi 631, expressed, RIKEN cDNA 9930012E13 gene, C87398, AA120551, Braf transforming gene 2, D6Ertd631e, expressed sequence AA473386, AA473386, 9930012E13Rik
Source: MGI:88190
Biotype: protein coding gene
Tgfb1
(Mus musculus)Gene
Name: transforming growth factor, beta 1
Synonyms: Tgfb-1, TGF-beta 1, Tgfb, TGFbeta1, TGF-beta1
Source: MGI:98725
Biotype: protein coding gene