Version: 8.1.0Date: Fri Apr 18 2025
Gene Biological Process: apoptotic nuclear changes Molecular Function: catalytic activity
Top2a
(Mus musculus)Gene
Name: topoisomerase (DNA) II alpha
Synonyms: DNA Topoisomerase II alpha, Top-2, topoisomerase (DNA) II
Source: MGI:98790
Biotype: protein coding gene
TOP2A
(Homo sapiens)Gene
Name: DNA topoisomerase II alpha
Synonyms: DNA topoisomerase II, 170 kD, DNA topoisomerase 2-alpha, topoisomerase (DNA) II alpha 170kDa, DNA topoisomerase (ATP-hydrolyzing), TOPIIA, TOP2, TP2A, topoisomerase (DNA) II alpha, DNA gyrase, TOP2alpha, DNA topoisomerase II, alpha isozyme
Source: HGNC:11989
Biotype: protein coding gene
KDM4A
(Homo sapiens)Gene
Name: lysine demethylase 4A
Synonyms: [histone H3]-trimethyl-L-lysine(9) demethylase 4A, jumonji domain containing 2A, JMJD2, TDRD14A, jumonji C domain-containing histone demethylase 3A, lysine-specific demethylase 4A, jumonji domain containing 2, JHDM3A, lysine (K)-specific demethylase 4A, JMJD2A, KIAA0677, jumonji domain-containing protein 2A, [histone H3]-trimethyl-L-lysine(36) demethylase 4A, jmjC domain-containing histone demethylation protein 3A, tudor domain containing 14A
Source: HGNC:22978
Biotype: protein coding gene
ACVR1C
(Homo sapiens)Gene
Name: activin A receptor type 1C
Synonyms: activin A receptor type IC, ACVRLK7, ACTR-IC, activin A receptor, type IC, ALK7, activin receptor-like kinase 7, activin receptor type IC, ALK-7, activin receptor type-1C
Source: HGNC:18123
Biotype: protein coding gene
DICER1
(Homo sapiens)Gene
Name: dicer 1, ribonuclease III
Synonyms: DCR1, Dicer1, Dcr-1 homolog, RMSE2, helicase-moi, multinodular goitre 1, Dicer, Dicer1e, dicer 1 ribonuclease III, GLOW, MNG1, helicase MOI, K12H4.8-LIKE, dicer 1, double-stranded RNA-specific endoribonuclease, KIAA0928, helicase with RNAse motif, endoribonuclease Dicer, aviD, dicer 1, ribonuclease type III, HERNA
Source: HGNC:17098
Biotype: protein coding gene
Dcr-2
(Drosophila melanogaster)Gene
Name: Dicer-2
Synonyms: DCR2, dDcr2, Dicer, DCR-2, Dicer-2, cg6493, CG6493, DICER2, Dicer 2, DICER, dicer-2, dcr2, dcr, Dcr, Dicer-II, dmDcr-2, dcr-2, Dicer2, dicer, DICER-2, DmDcr-2, dic2, dicer2, Dcr2
Source: FB:FBgn0034246
Biotype: protein coding gene
Acvr1c
(Mus musculus)Gene
Name: activin A receptor, type IC
Synonyms: habrec1, Alk7, ALK7, Alk-7
Source: MGI:2661081
Biotype: protein coding gene
ERN2
(Homo sapiens)Gene
Name: endoplasmic reticulum to nucleus signaling 2
Synonyms: hIRE2p, IRE2p, ER to nucleus signalling 2, inositol-requiring protein 2, IRE1b, IRE1, S. cerevisiae, homolog of, inositol-requiring 1 beta, endoplasmic reticulum-to-nucleus signaling 2, ire1-beta, IRE1 beta, endoplasmic reticulum to nucleus signalling 2, serine/threonine-protein kinase/endoribonuclease IRE2
Source: HGNC:16942
Biotype: protein coding gene
nuc-1
(Caenorhabditis elegans)Gene
Name: abnormal NUClease 1
Synonyms: CELE_C07B5.5, C07B5.5
Source: WB:WBGene00003828
Biotype: protein coding gene
Dicer1
(Mus musculus)Gene
Name: dicer 1, ribonuclease type III
Synonyms: RIKEN cDNA 1110006F08 gene, Dicer1, Dcr-1 homolog (Drosophila), DNA segment, Chr 12, ERATO Doi 7, expressed, D12Ertd7e, mKIAA0928, 1110006F08Rik
Source: MGI:2177178
Biotype: protein coding gene
Endog
(Mus musculus)Gene
Name: endonuclease G
Synonyms: Not Available
Source: MGI:1261433
Biotype: protein coding gene
DNASE2
(Homo sapiens)Gene
Name: deoxyribonuclease 2, lysosomal
Synonyms: DNL2, lysosomal DNase II, DNL, DNASE2A, acid DNase, R31240_2, DNase II, lysosomal, deoxyribonuclease II alpha, AIPCS, deoxyribonuclease II, lysosomal, deoxyribonuclease-2-alpha, DNase II alpha
Source: HGNC:2960
Biotype: protein coding gene
CECR2
(Homo sapiens)Gene
Name: CECR2 histone acetyl-lysine reader
Synonyms: chromatin remodeling regulator CECR2, CECR2, histone acetyl-lysine reader, KIAA1740, cat eye syndrome chromosome region, candidate 2, cat eye syndrome critical region protein 2, AC004019.18
Source: HGNC:1840
Biotype: protein coding gene
ACIN1
(Homo sapiens)Gene
Name: apoptotic chromatin condensation inducer 1
Synonyms: apoptotic chromatin condensation inducer in the nucleus, functional spliceosome-associated protein 152, fSAP152, DKFZp667N107, ACINUS, KIAA0670, ACN
Source: HGNC:17066
Biotype: protein coding gene
Blvra
(Mus musculus)Gene
Name: biliverdin reductase A
Synonyms: RIKEN cDNA 0610006A11 gene, biliverdin reductase, Blvr, RIKEN cDNA 2500001N03 gene, 2500001N03Rik, 0610006A11Rik
Source: MGI:88170
Biotype: protein coding gene
ENDOG
(Homo sapiens)Gene
Name: endonuclease G
Synonyms: mitochondrial endonuclease G, endonuclease G, mitochondrial, FLJ27463, endo G
Source: HGNC:3346
Biotype: protein coding gene
NUC1
(Saccharomyces cerevisiae)Gene
Name: NUClease
Synonyms: YJL208C
Source: SGD:S000003744
Biotype: protein coding gene
dcr-1
(Caenorhabditis elegans)Gene
Name: DiCer Related 1
Synonyms: K12H4.8, let-740, eri-4, CELE_K12H4.8
Source: WB:WBGene00000939
Biotype: protein coding gene
cyn-13
(Caenorhabditis elegans)Gene
Name: CYclophyliN 13
Synonyms: CELE_Y116A8C.34, cyp-13, Y116A8C.34
Source: WB:WBGene00000889
Biotype: protein coding gene
dicer1
(Danio rerio)Gene
Name: dicer 1, ribonuclease type III
Synonyms: fc39d11, wu:fc39d11, fc74b05, wu:fc74b05
Source: ZFIN:ZDB-GENE-030131-3445
Biotype: protein coding gene
Dnase2a
(Mus musculus)Gene
Name: deoxyribonuclease II alpha
Synonyms: deoxyribonuclease II, Dnase2
Source: MGI:1329019
Biotype: protein coding gene
Dffb
(Rattus norvegicus)Gene
Name: DNA fragmentation factor subunit beta
Synonyms: DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase), DFF-40, caspase-activated DNase, DNA fragmentation factor, beta polypeptide (caspase-activated DNase), DNA fragmentation factor 40 kD beta polypeptide (caspase-activated DNase), caspase-activated deoxyribonuclease, Cad, DNA fragmentation factor 40 kDa subunit, DNA fragmentation factor, 40 kD, beta polypeptide (caspase-activated DNase), DNA fragmentation factor, beta subunit
Source: RGD:620335
Biotype: protein coding gene
Ern2
(Mus musculus)Gene
Name: endoplasmic reticulum to nucleus signalling 2
Synonyms: inositol-requiring 1 beta (yeast), Ire1b
Source: MGI:1349436
Biotype: protein coding gene
crn-1
(Caenorhabditis elegans)Gene
Name: Cell-death-Related Nuclease 1
Synonyms: Y47G6A.8, fen-1, CELE_Y47G6A.8
Source: WB:WBGene00000794
Biotype: protein coding gene
wah-1
(Caenorhabditis elegans)Gene
Name: Worm AIF (apoptosis inducing factor) Homolog 1
Synonyms: CELE_Y56A3A.32, Y56A3A.32
Source: WB:WBGene00006937
Biotype: protein coding gene
Sharpin
(Mus musculus)Gene
Name: SHANK-associated RH domain interacting protein
Synonyms: Conneck1, cpdm, expressed sequence AW121341, RIKEN cDNA 0610041B22 gene, AW121341, 0610041B22Rik, SIPL1, chronic proliferative dermatitis
Source: MGI:1913331
Biotype: protein coding gene
Drep4
(Drosophila melanogaster)Gene
Name: DNA fragmentation factor-related protein 4
Synonyms: Rep4, CG9414, Caspase-activated DNase, CAD, Drep4, dCAD, drep4, DREP-4, DREP4, Drep-4
Source: FB:FBgn0028406
Biotype: protein coding gene
Dcr-1
(Drosophila melanogaster)Gene
Name: Dicer-1
Synonyms: DCR1, dmDcr1, Dicer, DICER-1, DCR-1, DICER1, DICER, Dicer 1, dcr 1, dcr1, dicer-1, Dcr, cg4792, CG4792, Dicer-1, dcr-1, dicer, Dicer1, dicer1, Dcr1
Source: FB:FBgn0039016
Biotype: protein coding gene
DNaseII
(Drosophila melanogaster)Gene
Name: Deoxyribonuclease II
Synonyms: dDNase II, DNase-1, DNase 1, acid DNase, deoxyribonuclease II, dnaseII[lo], DNase II, dnaseII, DNase1, DNase, CG7780, Deoxyribonuclease 1
Source: FB:FBgn0000477
Biotype: protein coding gene
CG12917
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: Not Available
Source: FB:FBgn0033490
Biotype: protein coding gene
Ern2
(Rattus norvegicus)Gene
Name: endoplasmic reticulum to nucleus signaling 2
Synonyms: LOC365363, endoplasmic reticulum (ER) to nucleus signalling 2, serine/threonine-protein kinase/endoribonuclease IRE2
Source: RGD:1308743
Biotype: protein coding gene
crn-3
(Caenorhabditis elegans)Gene
Name: Cell-death-Related Nuclease 3
Synonyms: CELE_C14A4.4, C14A4.4, exos-10
Source: WB:WBGene00000796
Biotype: protein coding gene
Top2a
(Rattus norvegicus)Gene
Name: DNA topoisomerase II alpha
Synonyms: topoisomerase (DNA) 2 alpha, DNA topoisomerase 2-alpha, topoisomerase (DNA) II alpha, DNA topoisomerase II, alpha isozyme
Source: RGD:62048
Biotype: protein coding gene
Tengl4
(Drosophila melanogaster)Gene
Name: Testis EndoG-Like 4
Synonyms: CG4683
Source: FB:FBgn0037857
Biotype: protein coding gene
Dnase2b
(Mus musculus)Gene
Name: deoxyribonuclease II beta
Synonyms: Dlad, AI526873, expressed sequence AI526873, DnaseIIb, UOX
Source: MGI:1913283
Biotype: protein coding gene
Dicer1
(Rattus norvegicus)Gene
Name: dicer 1 ribonuclease III
Synonyms: Dicer1, Dcr-1 homolog, LOC299284, Dicer1, Dcr-1 homolog (Drosophila), endoribonuclease Dicer, dicer 1, ribonuclease type III
Source: RGD:1309381
Biotype: protein coding gene
Tengl2
(Drosophila melanogaster)Gene
Name: Testis EndoG-Like 2
Synonyms: CG32463, CG17006
Source: FB:FBgn0052463
Biotype: protein coding gene
Tengl1
(Drosophila melanogaster)Gene
Name: Testis EndoG-Like 1
Synonyms: CG31682, CG17006, BcDNA:AT02809
Source: FB:FBgn0051682
Biotype: protein coding gene
crn-6
(Caenorhabditis elegans)Gene
Name: Cell-death-Related Nuclease 6
Synonyms: CELE_K04H4.6, K04H4.6
Source: WB:WBGene00000799
Biotype: protein coding gene
CG6839
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: Not Available
Source: FB:FBgn0036831
Biotype: protein coding gene
Dnase1l3
(Mus musculus)Gene
Name: deoxyribonuclease 1-like 3
Synonyms: DNasegamma
Source: MGI:1314633
Biotype: protein coding gene
Dffb
(Mus musculus)Gene
Name: DNA fragmentation factor, beta subunit
Synonyms: 5730477D02Rik, Didff, caspase-activated DNase, CPAN, CAD, Cad, 40kDa, RIKEN cDNA 5730477D02 gene, DNase inhibited by DNA fragmentation factor, DFF40
Source: MGI:1196287
Biotype: protein coding gene
crn-7
(Caenorhabditis elegans)Gene
Name: Cell-death-Related Nuclease 7
Synonyms: CELE_F09G8.2, tag-198, F09G8.2
Source: WB:WBGene00007056
Biotype: protein coding gene
Sharpin
(Rattus norvegicus)Gene
Name: SHANK-associated RH domain interactor
Synonyms: SHANK-associated RH domain interacting protein, Conneck1, MGC93373, shank-interacting protein, shank-associated RH domain-interacting protein
Source: RGD:631353
Biotype: protein coding gene
dnase2
(Danio rerio)Gene
Name: deoxyribonuclease II, lysosomal
Synonyms: wu:fa56d08, fa56d08, fa92d01, wu:fa92d01
Source: ZFIN:ZDB-GENE-010724-16
Biotype: protein coding gene
dffb
(Danio rerio)Gene
Name: DNA fragmentation factor, beta polypeptide (caspase-activated DNase)
Synonyms: CAD
Source: ZFIN:ZDB-GENE-030826-4
Biotype: protein coding gene
Dnase1l3
(Rattus norvegicus)Gene
Name: deoxyribonuclease 1L3
Synonyms: deoxyribonuclease gamma-like, DNaseY, deoxyribonuclease gamma, deoxyribonuclease I-like 3, deoxyribonuclease 1-like 3, DNase I-like 3, LOC103690049, MGC108624, DNase gamma
Source: RGD:620669
Biotype: protein coding gene
Kdm4a
(Rattus norvegicus)Gene
Name: lysine demethylase 4A
Synonyms: jumonji domain containing 2A, Jmjd2a, LOC313539, lysine-specific demethylase 4A, lysine (K)-specific demethylase 4A
Source: RGD:1306378
Biotype: protein coding gene
CG14062
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: LP23408p
Source: FB:FBgn0039592
Biotype: protein coding gene
DNASE1L3
(Homo sapiens)Gene
Name: deoxyribonuclease 1L3
Synonyms: DNAS1L3, deoxyribonuclease 1 like 3, DNase I homolog protein 2, deoxyribonuclease I-like 3, DHP2, LS-DNase, SLEB16, DNase gamma, D3, deoxyribonuclease I-like III, DNaseY, deoxyribonuclease gamma, Liver and spleen DNase, deoxyribonuclease I like 3, DNase I-like 3, LSD, DNase I homolog protein DHP2
Source: HGNC:2959
Biotype: protein coding gene