Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: regulation of cellular pH Molecular Function: metal ion binding
CFTR
(Homo sapiens)Gene
Name: CF transmembrane conductance regulator
Synonyms: CF, ABCC7, cystic fibrosis transmembrane conductance regulator, atp-binding cassette (sub-family c, member 7), MRP7, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7, dJ760C5.1, ATP-binding cassette sub-family C member 7, ABC35, cystic fibrosis transmembrane conductance regulator, TNR-CFTR, cystic fibrosis transmembrane conductance regulating, channel conductance-controlling ATPase, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Source: HGNC:1884
Biotype: protein coding gene
BCL2
(Homo sapiens)Gene
Name: BCL2 apoptosis regulator
Synonyms: Bcl-2, protein phosphatase 1, regulatory subunit 50, Bcl-2a, B-cell CLL/lymphoma 2, PPP1R50, Bcl-2ß, apoptosis regulator Bcl-2, b-cell leukemia/lymphoma 2, BCL2, apoptosis regulator
Source: HGNC:990
Biotype: protein coding gene
Cftr
(Mus musculus)Gene
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7, expressed sequence AW495489, AW495489, RGD1561193
Source: MGI:88388
Biotype: protein coding gene
Oca2
(Mus musculus)Gene
Name: oculocutaneous albinism II
Synonyms: p, D7H15S12, D7Icr28RN, DNA segment, Chr 7, human D15S12, D7Nic1, DNA segment, Chr 7, Institute for Cancer Research 28RN, DNA segment, Chr 7, Nicholls 1, pink-eyed dilution
Source: MGI:97454
Biotype: protein coding gene
ClC-c
(Drosophila melanogaster)Gene
Name: Chloride channel-c
Synonyms: Clc-c, anon-WO0138359.7, clc-c, CG5284, DmClCc, DmClC-c
Source: FB:FBgn0036566
Biotype: protein coding gene
MAPK1
(Homo sapiens)Gene
Name: mitogen-activated protein kinase 1
Synonyms: PRKM1, PRKM2, NS13, p41mapk, mitogen activated protein kinase 1, ERT1, p41, p40, P42MAPK, extracellular signal-regulated kinase 2, ERK-2, ERK2, p38, MAP kinase isoform p42, p42-MAPK, MAP kinase 2, MAP kinase 1, mitogen-activated protein kinase 2, MAPK2, protein tyrosine kinase ERK2, MAPK 2, ERK
Source: HGNC:6871
Biotype: protein coding gene
CLCN3
(Homo sapiens)Gene
Name: chloride voltage-gated channel 3
Synonyms: chloride transporter ClC-3, H(+)/Cl(-) exchange transporter 3, ClC-3, NEDSBA, DKFZp564I0463, CLC3, NEDHYBA, chloride channel, voltage-sensitive 3, chloride channel protein 3, chloride channel 3
Source: HGNC:2021
Biotype: protein coding gene
MAPK3
(Homo sapiens)Gene
Name: mitogen-activated protein kinase 3
Synonyms: PRKM3, MGC20180, HUMKER1A, insulin-stimulated MAP2 kinase, HS44KDAP, P44ERK1, MAP kinase isoform p44, microtubule-associated protein 2 kinase, ERT2, p44-MAPK, p44-ERK1, extracellular signal-regulated kinase 1, P44MAPK, ERK-1, ERK1, MAP kinase 3, MAP kinase 1, mitogen-activated protein kinase 1, MAPK 3, extracellular signal-related kinase 1, MAPK 1
Source: HGNC:6877
Biotype: protein coding gene
ATP6V0C
(Homo sapiens)Gene
Name: ATPase H+ transporting V0 subunit c
Synonyms: Vma3, V-type proton ATPase 16 kDa proteolipid subunit, VPPC, ATP6L, V-type proton ATPase 16 kDa proteolipid subunit c, vacuolar H+ ATPase proton channel subunit, vacuolar ATP synthase 16 kDa proteolipid subunit, VATL, ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c, EPEO3, vacuolar proton pump 16 kDa proteolipid subunit, ATP6C, ATPL, vacuolar proton pump 16 kDa proteolipid subunit c, V-ATPase subunit c, V-ATPase 16 kDa proteolipid subunit, vacuolar proton pump, 16 kDa subunit, H(+)-transporting two-sector ATPase, 16 kDa subunit, V-ATPase 16 kDa proteolipid subunit c
Source: HGNC:855
Biotype: protein coding gene
CLN3
(Homo sapiens)Gene
Name: CLN3 lysosomal/endosomal transmembrane protein, battenin
Synonyms: BTS, batten disease protein, battenin, MGC102840, BTN1, CLN3, battenin, JNCL, ceroid-lipofuscinosis, neuronal 3
Source: HGNC:2074
Biotype: protein coding gene
HVCN1
(Homo sapiens)Gene
Name: hydrogen voltage gated channel 1
Synonyms: HV1, MGC15619, voltage-gated hydrogen channel 1, VSOP, voltage sensor domain-only protein, hydrogen voltage-gated channel 1
Source: HGNC:28240
Biotype: protein coding gene
RAB7A
(Homo sapiens)Gene
Name: RAB7A, member RAS oncogene family
Synonyms: ras-related protein Rab-7a, RAB7, RAB7, member RAS oncogene family, FLJ20819, PRO2706, Ras-associated protein RAB7, Charcot-Marie-Tooth neuropathy 2B, CMT2B
Source: HGNC:9788
Biotype: protein coding gene
ATP6V1B2
(Homo sapiens)Gene
Name: ATPase H+ transporting V1 subunit B2
Synonyms: DOOD, Vma2, H+ transporting two-sector ATPase, V-type proton ATPase subunit B, brain isoform, V-ATPase B2 subunit, ATP6B2, HO57, ATP6B1B2, V-ATPase subunit B 2, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2, vacuolar H+-ATPase 56,000 subunit, atpase, h+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kda, isoform 2, VATB, vacuolar proton pump subunit B 2, testicular secretory protein Li 65, VPP3, ZLS2, endomembrane proton pump 58 kDa subunit
Source: HGNC:854
Biotype: protein coding gene
Bcl2
(Mus musculus)Gene
Name: B cell leukemia/lymphoma 2
Synonyms: Bcl-2, RIKEN cDNA D630044D05 gene, D630044D05Rik, D830018M01Rik, C430015F12Rik, RIKEN cDNA C430015F12 gene, RIKEN cDNA D830018M01 gene, expressed sequence AW986256, AW986256
Source: MGI:88138
Biotype: protein coding gene
GRN
(Homo sapiens)Gene
Name: granulin precursor
Synonyms: proepithelin, acrogranin, GP88, PC cell-derived growth factor, PEPI, epithelin, GEP, PGRN, CLN11, PCDGF, glycoprotein of 88 Kda, progranulin, glycoprotein 88, granulin-epithelin, granulins, FTD2, granulin
Source: HGNC:4601
Biotype: protein coding gene
NHX1
(Saccharomyces cerevisiae)Gene
Name: Na+/H+ eXchanger
Synonyms: VPL27, VPS44, YDR456W, NHA2
Source: SGD:S000002864
Biotype: protein coding gene
Mapk1
(Rattus norvegicus)Gene
Name: mitogen activated protein kinase 1
Synonyms: extracellular-signal-regulated kinase 2, ERT1, extracellular-signal-regulated kinase 1, extracellular signal-regulated kinase 2, ERK-2, Erk2, MAP kinase 2, p42-MAPK, MAP kinase isoform p42, MAP kinase 1, mitogen-activated protein kinase 2, mitogen-activated protein kinase 1, MAPK 1, MAPK 2
Source: RGD:70500
Biotype: protein coding gene
SLC11A1
(Homo sapiens)Gene
Name: solute carrier family 11 member 1
Synonyms: LSH, NRAMP, solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1, solute carrier family 11 (sodium/phosphate symporters), member 1, NRAMP 1, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1, NRAMP1, Leishmaniasis resistance, natural resistance-associated macrophage protein 1
Source: HGNC:10907
Biotype: protein coding gene
VMA2
(Saccharomyces cerevisiae)Gene
Name: Vacuolar Membrane Atpase
Synonyms: VAT2, YBR127C, ATPSV
Source: SGD:S000000331
Biotype: protein coding gene
Gpr89
(Mus musculus)Gene
Name: G protein-coupled receptor 89
Synonyms: RGD1304837, 4933412D19Rik, RIKEN cDNA 4933412D19 gene, SH120
Source: MGI:1914799
Biotype: protein coding gene
Bcl2
(Rattus norvegicus)Gene
Name: BCL2, apoptosis regulator
Synonyms: Bcl-2, B cell lymphoma 2 associated oncogene, Bcl-2alpha, ENSRNOG00000067693, B-cell CLL/lymphoma 2, Bcl2-like protein, apoptosis regulator Bcl-2, B-cell leukemia/lymphoma 2, B cell leukemia/lymphoma 2
Source: RGD:2199
Biotype: protein coding gene
VMA1
(Saccharomyces cerevisiae)Gene
Name: Vacuolar Membrane Atpase
Synonyms: YDL185W, CLS8, TFP1
Source: SGD:S000002344
Biotype: protein coding gene
ALY2
(Saccharomyces cerevisiae)Gene
Name: Arrestin-Like Yeast protein
Synonyms: YJL084C, ART3
Source: SGD:S000003620
Biotype: protein coding gene
cxcr4b
(Danio rerio)Gene
Name: chemokine (C-X-C motif), receptor 4b
Synonyms: drCXCR4b1, ody, cb403, odysseus, zgc:109863
Source: ZFIN:ZDB-GENE-010614-1
Biotype: protein coding gene
Tasl
(Mus musculus)Gene
Name: TLR adaptor interacting with endolysosomal SLC15A4
Synonyms: 5430427O19Rik, RIKEN cDNA 5430427O19 gene, RGD1565785
Source: MGI:1918648
Biotype: protein coding gene
DBF2
(Saccharomyces cerevisiae)Gene
Name: DumbBell Former
Synonyms: YGR092W
Source: SGD:S000003324
Biotype: protein coding gene
Lamp1
(Mus musculus)Gene
Name: lysosomal-associated membrane protein 1
Synonyms: CD107a, AI196048, Lamp-1, LGP120, expressed sequence AI196048, Perk
Source: MGI:96745
Biotype: protein coding gene
RAV1
(Saccharomyces cerevisiae)Gene
Name: Regulator of (H+)-ATPase in Vacuolar membrane
Synonyms: SOI3, YJR033C
Source: SGD:S000003794
Biotype: protein coding gene
SKP1
(Saccharomyces cerevisiae)Gene
Name: Suppressor of Kinetochore Protein mutant
Synonyms: CBF3D, MGO1, YDR328C
Source: SGD:S000002736
Biotype: protein coding gene
Cftr
(Rattus norvegicus)Gene
Name: CF transmembrane conductance regulator
Synonyms: ATP-binding cassette transporter sub-family C member 7, LOC500041, ATP-binding cassette sub-family C member 7, cystic fibrosis transmembrane conductance regulator, channel conductance-controlling ATPase, cystic fibrosis transmembrane conductance regulator homolog (human), cystic fibrosis transmembrane conductance regulator homolog, similar to cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7), cAMP-dependent chloride channel, RGD1561193
Source: RGD:2332
Biotype: protein coding gene
vha-12
(Caenorhabditis elegans)Gene
Name: Vacuolar H ATPase 12
Synonyms: CELE_F20B6.2, F20B6.2
Source: WB:WBGene00006921
Biotype: protein coding gene
VMA3
(Saccharomyces cerevisiae)Gene
Name: Vacuolar Membrane Atpase
Synonyms: CLS7, CUP5, GEF2, YEL027W
Source: SGD:S000000753
Biotype: protein coding gene
Mapk1
(Mus musculus)Gene
Name: mitogen-activated protein kinase 1
Synonyms: AU018647, AA407128, expressed sequence C78273, ERT1, ERK-2, Prkm1, protein kinase, mitogen activated kinase 1, expressed sequence AA407128, p42mapk, Erk2, expressed sequence AU018647, RIKEN cDNA 9030612K14 gene, p42-MAPK, MAPK2, elk related tyrosine kinase 2, 9030612K14Rik, C78273
Source: MGI:1346858
Biotype: protein coding gene
Avp
(Mus musculus)Gene
Name: arginine vasopressin
Synonyms: Vsp, ADH, DI, vasopressin, Vas, Vp, VP
Source: MGI:88121
Biotype: protein coding gene
ALY1
(Saccharomyces cerevisiae)Gene
Name: Arrestin-Like Yeast protein
Synonyms: YKR021W, ART6
Source: SGD:S000001729
Biotype: protein coding gene
Slc9a3
(Mus musculus)Gene
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3
Synonyms: RIKEN cDNA 9030624O13 gene, expressed sequence AI930210, NHE3, Nhe3, NHE-3, 9030624O13Rik, AI930210
Source: MGI:105064
Biotype: protein coding gene
YHC3
(Saccharomyces cerevisiae)Gene
Name: Yeast Homolog of human Cln3
Synonyms: YJL059W, BTN1
Source: SGD:S000003595
Biotype: protein coding gene
Mafg
(Rattus norvegicus)Gene
Name: MAF bZIP transcription factor G
Synonyms: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G, v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian), transcription factor MafG, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G, v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
Source: RGD:619953
Biotype: protein coding gene
rab-14
(Caenorhabditis elegans)Gene
Name: RAB family 14
Synonyms: CELE_K09A9.2, K09A9.2
Source: WB:WBGene00004276
Biotype: protein coding gene
unc-32
(Caenorhabditis elegans)Gene
Name: UNCoordinated 32
Synonyms: CELE_ZK637.8, ZK637.8
Source: WB:WBGene00006768
Biotype: protein coding gene
Avpr1a
(Mus musculus)Gene
Name: arginine vasopressin receptor 1A
Synonyms: V1a, AVPR, V1aR
Source: MGI:1859216
Biotype: protein coding gene
MEH1
(Saccharomyces cerevisiae)Gene
Name: Multicopy suppressor of Ers1 Hygromycin B sensitivity
Synonyms: YKR007W, EGO1, GSE2
Source: SGD:S000001715
Biotype: protein coding gene
ATP6V0A1
(Homo sapiens)Gene
Name: ATPase H+ transporting V0 subunit a1
Synonyms: vacuolar proton translocating ATPase 116 kDa subunit A, V-type proton ATPase 116 kDa subunit a1, vacuolar proton pump, subunit 1, ATP6N1A, Vph1, vacuolar-type H(+)-ATPase 115 kDa subunit, ATP6N1, H(+)-transporting two-sector ATPase, 116 kDa accessory protein A1, Stv1, vacuolar adenosine triphosphatase subunit Ac116, DEE104, V-ATPase 116 kDa subunit a1, ATPase, H+ transporting, lysosomal V0 subunit a1, V-ATPase 116 kDa, V-type proton ATPase 116 kDa subunit a, a1, vacuolar proton pump subunit 1, NEDEBA, VPP1, V-type proton ATPase 116 kDa subunit a 1, V-ATPase 116 kDa subunit a 1, ATPase, H+ transporting, lysosomal non-catalytic accessory protein 1 (110/116kD), V-type proton ATPase 116 kDa subunit a isoform 1, V-ATPase subunit a1, DKFZp781J1951, clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit, ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110/116kD)
Source: HGNC:865
Biotype: protein coding gene
Tmem106b
(Mus musculus)Gene
Name: transmembrane protein 106B
Synonyms: AI661344, RIKEN cDNA 6430519M21 gene, 6430519M21Rik, 2310036D22Rik, expressed sequence AI428776, 5830455K21Rik, LRRGT00101, RIKEN cDNA 2310036D22 gene, AI428776, expressed sequence AI661344, RIKEN cDNA 5830455K21 gene
Source: MGI:1919150
Biotype: protein coding gene
Grn
(Mus musculus)Gene
Name: granulin
Synonyms: epithelin, PGRN, Pgrn, acrogranulin, progranulin, PC cell-derived growth factor, PEPI
Source: MGI:95832
Biotype: protein coding gene
Aqp11
(Mus musculus)Gene
Name: aquaporin 11
Synonyms: sjds, expressed sequence AI648923, AI648923, sudden juvenile death syndrome, 1700015P13Rik, RIKEN cDNA 1700015P13 gene
Source: MGI:1913583
Biotype: protein coding gene
Slc4a10
(Mus musculus)Gene
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Source: MGI:2150150
Biotype: protein coding gene
ATP5F1B
(Homo sapiens)Gene
Name: ATP synthase F1 subunit beta
Synonyms: ATP synthase subunit beta, mitochondrial, ATP5B, MGC5231, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide, ATPSB, ATPMB, epididymis secretory protein Li 271, mitochondrial ATP synthetase, beta subunit, HEL-S-271, mitochondrial ATP synthase beta subunit, HUMOP2
Source: HGNC:830
Biotype: protein coding gene
Vha16-1
(Drosophila melanogaster)Gene
Name: Vacuolar H[+] ATPase 16kD subunit 1
Synonyms: ductin, V-ATPase, Ductin subunit C, MRE15, Vacuolar H[+] ATPase 16kD subunit, CG3161, Vacuolar H[+] ATPase subunit 16-1, Vha1, c subunit, Ductin, DucC, mRNA-like ncRNA in embryogenesis 15, ductin, vacuolar H(+)-ATPase subunit C proteolipid, BcDNA:SD02875, Vha16, EP2372, vha16, Vhac, vha16-1, ATP6V0C, v-ATPase, Vacuolar H[+]-ATPase c subunit
Source: FB:FBgn0262736
Biotype: protein coding gene
VPS45
(Saccharomyces cerevisiae)Gene
Name: Vacuolar Protein Sorting
Synonyms: VPL28, STT10, YGL095C
Source: SGD:S000003063
Biotype: protein coding gene