Version: 8.0.0Date: Tue Jan 28 2025
Gene Diseases: peripheral nervous system disease
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Pten
(Mus musculus)Gene
Name: phosphatase and tensin homolog
Synonyms: B430203M17Rik, RIKEN cDNA B430203M17 gene, expressed sequence AI463227, RIKEN cDNA 2310035O07 gene, TEP1, Mmac, A130070J02Rik, MMAC1, AI463227, 2310035O07Rik, RIKEN cDNA A130070J02 gene
Source: MGI:109583
Biotype: protein coding gene
FLNA
(Homo sapiens)Gene
Name: filamin A
Synonyms: OPD, FLN-A, filamin-1, FLN1, FLN, XMVD, filamin A, alpha, XLVD, actin binding protein 280, FG syndrome 2, alpha filamin, MNS, filamin 1, DKFZp434P031, FMD, CSBS, FGS2, endothelial actin-binding protein, non-muscle filamin, OPD2, OPD1, NHBP, alpha-filamin, FLJ43642, filamin-A, ABPX, ABP-280, CVD1
Source: HGNC:3754
Biotype: protein coding gene
Pax6
(Mus musculus)Gene
Name: paired box 6
Synonyms: 1500038E17Rik, AEY11, RIKEN cDNA 1500038E17 gene, Pax-6, Sey, gsf abnormal eyes 11, Dey, Dickie's small eye, Gsfaey11, small eye
Source: MGI:97490
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
Bmp4
(Mus musculus)Gene
Name: bone morphogenetic protein 4
Synonyms: Bmp2b, bone morphogenetic protein 2b, BOMPR4A, Bmp2b-1, Bmp-4, bone morphogenetic protein 2b 1, Bmp2b1
Source: MGI:88180
Biotype: protein coding gene
H2-K1
(Mus musculus)Gene
Name: histocompatibility 2, K1, K region
Synonyms: RT1-A2n, RT1-CE12, rt1-El, RT1-A, RT1-CE7, RT1-E2, RT1A-1, RT1A-2, RT1-C/E1, RT1-C/E5, RT1.A2(N), RT1-C/E3, RT1-C/E4, RT1.A1(N), RT1-A1n, RT1-C/E7, H-2K
Source: MGI:95904
Biotype: protein coding gene
daf-2
(Caenorhabditis elegans)Gene
Name: abnormal DAuer Formation 2
Synonyms: Y55D5A.5, CELE_Y55D5A.5
Source: WB:WBGene00000898
Biotype: protein coding gene
ss
(Drosophila melanogaster)Gene
Name: spineless
Synonyms: Ss, SS, ssa, Spineless, CG6993, aristapedia, dAHR, AhR, AHR, spineless-aristapedia
Source: FB:FBgn0003513
Biotype: protein coding gene
PTEN
(Homo sapiens)Gene
Name: phosphatase and tensin homolog
Synonyms: MHAM, DEC, PTENepsilon, 10q23del, phosphatase and tensin-like protein, PTEN1, mitochondrial PTENalpha, GLM2, PTEN variant PTEN-K267Rfs*9, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, CWS1, mutated in multiple advanced cancers 1, MMAC1, PTEN variant PTEN-L247*, PTEN variant PTEN-R234Afs*11, mitochondrial phosphatase and tensin protein alpha, TEP1, PTENgama, inositol polyphosphate 3-phosphatase, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, BZS, PTENbeta, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MGC11227
Source: HGNC:9588
Biotype: protein coding gene
EGFR
(Homo sapiens)Gene
Name: epidermal growth factor receptor
Synonyms: PIG61, NNCIS, receptor tyrosine-protein kinase erbB-1, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), erythroblastic leukemia viral (v-erb-b) oncogene homolog, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, NISBD2, HER1
Source: HGNC:3236
Biotype: protein coding gene
HLA-A
(Homo sapiens)Gene
Name: major histocompatibility complex, class I, A
Synonyms: HLA class I histocompatibility antigen, A-1 alpha chain, HLA A, HLAA, MHC class I antigen A*34, MHC class I antigen A*33, HLA class I histocompatibility antigen, A-43 alpha chain, MHC class I antigen A*32, MHC class I antigen A*31, HLA-A11, MHC class II antigen, HLA class I histocompatibility antigen, A-80 alpha chain, MHC class I antigen A*36, HLA class I histocompatibility antigen, A-23 alpha chain, HLA class I histocompatibility antigen, A-66 alpha chain, HLA class I histocompatibility antigen, A-9 alpha chain, aw-19, MHC class I antigen HLA-A33, truncated MHC class I antigen, MHC class I antigen A*30, MHC class I antigen A*74, MHC class I antigen A*1, leucocyte antigen A, HLA-Aw33.1, MHC class I antigen A*43, MHC class I anti, MHC class I antigen HLA-A heavy chain, HLA class I histocompatibility antigen, A-69 alpha chain-like, HLA class I histocompatibility antigen, A-26 alpha chain, HLA class I histocompatibility antigen, A-36 alpha chain, MHC class I antigen A*80, HLA class I histocompatibility antigen, A-28 alpha chain, aw-24, HLA class I histocompatibility antigen, A-24 alpha chain, HLA class I histocompatibility antigen, A-25 alpha chain, HLA class I histocompatibility antigen, A-29 alpha chain, aw-66, LOC100507703, leucocyte antigen class I, HLA-DQB1, MHC class I antigene, antigen presenting molecule, HLA class I antigen, FLJ26655, HLA class I histocompatibility antigen, A-31 alpha chain, MHC leukocyte antigen, HLA class I histocompatibility antigen, A-10 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, MHC class I antigen A*11, HLA-A33, HLA class I histocompatibility antigen, A-34 alpha chain, Aw-69, HLA-A locus alpha 2 domain, Aw-68, aw-34, leukocyte antigen class I-A, aw-36, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, MHC class I antigen heavy chain, MHC class I antigen A*29, aw-80, MHC class I antigen A*2, MCH class I antigen, MHC class I antigen A*3, MHC class I antigen A*23, HLA-A null, MHC class I antigen A*66, MHC class I antigen A*26, MHC class I antigen A*69, MHC class I antigen A*25, MHC class I antigen A*24, MHC class I antigen A*68, MHC classI antigen, HLA locus, HLA class I histocompatibility antigen, A alpha chain, MHC Class I antigen, MHC class 1 antigen, aw-43, Aw-33, Aw-74, HLA-DRB1
Source: HGNC:4931
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, MGC1571, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2
Source: HGNC:613
Biotype: protein coding gene
PAX6
(Homo sapiens)Gene
Name: paired box 6
Synonyms: paired box 6 PAX6A-ASdel6-AS7 isoform, paired box homeotic gene-6, AN1, AN2, paired box 6 PAX6B-ASdel6 isoform, AN, paired box 6 PAX6A-del6 isoform, D11S812E, paired box protein Pax-6, MGDA, Aniridia 1, Aniridia 2, FVH1, paired box 6 PAX6-12a isoform, aniridia type II protein, oculorhombin, MGC17209, paired box 6 PAX6D isoform, ASGD5, WAGR, paired box 6 PAX6A-ASdel6 isoform, alternative protein PAX6
Source: HGNC:8620
Biotype: protein coding gene
dpp
(Drosophila melanogaster)Gene
Name: decapentaplegic
Synonyms: shv, DPP, Dpp, ho, TGF-b, blink, M(2)23AB, DmDPP, l(2)10638, M(2)LS1, Decapentaplegic/Bone Morphogenetic Protein, Haplo-insufficient, TGF-beta, Tg, CG9885, DPP-C, TGFbeta, blk, Tegula, Hin-d, Bmp, BMP, Decapentaplegic, bone morphogenetic protein, l(2)22Fa, Tgfbeta, heldout, Dpp/TGFbeta, bone morphogenic protein, shortvein, l(2)k17036, Dm-DPP
Source: FB:FBgn0000490
Biotype: protein coding gene
HOG1
(Saccharomyces cerevisiae)Gene
Name: High Osmolarity Glycerol response
Synonyms: YLR113W, SSK3
Source: SGD:S000004103
Biotype: protein coding gene
Kit
(Mus musculus)Gene
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: Dominant white spotting, gsf spotted coat 1, Fdc, c-KIT, Gsfsco1, dominant spotting, Ssm, gsf spotted coat 5, SCO5, Bs, SCO1, Tr-kit, W, CD117, spotted sterile male, Steel Factor Receptor, Gsfsow3, Gsfsco5, phenotype like Sl or W 3, belly-spot, SOW3
Source: MGI:96677
Biotype: protein coding gene
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
Flna
(Mus musculus)Gene
Name: filamin, alpha
Synonyms: dilated pupils 2, filamin 1, filamin-1, Dilp2, actin-binding protein 280, Fln1, GENA 379, RIKEN cDNA F730004A14 gene, F730004A14Rik, ABP-280, RGD1560614
Source: MGI:95556
Biotype: protein coding gene
Ttr
(Mus musculus)Gene
Name: transthyretin
Synonyms: TT, expressed sequence AA408768, AA408768, prealbumin, expressed sequence AI787086, expressed sequence D17860, Tbpa, Lr1, AI787086, D17860
Source: MGI:98865
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
DMD
(Homo sapiens)Gene
Name: dystrophin
Synonyms: truncated dystrophin, DXS270, mutant dystrophin, dystrophin (muscular dystrophy, Duchenne and Becker types), DXS272, mental retardation, X-linked 85, DXS239, DXS206, MRX85, BMD, DXS142, DXS230, DXS164, DXS268, CMD3B, DXS269
Source: HGNC:2928
Biotype: protein coding gene
Dmd
(Mus musculus)Gene
Name: dystrophin, muscular dystrophy
Synonyms: mdx, X-linked muscular dystrophy, Duchenne muscular dystrophy, Dp71, DNADMD1, pke, pyruvate kinase expression, Dp427, dys
Source: MGI:94909
Biotype: protein coding gene
SOD1
(Homo sapiens)Gene
Name: superoxide dismutase 1
Synonyms: Cu/Zn superoxide dismutase, ALS, SOD, superoxide dismutase [Cu-Zn], indophenoloxidase A, HEL-S-44, superoxide dismutase 1, soluble, epididymis secretory protein Li 44, SOD, soluble, STAHP, hSod1, superoxide dismutase, cystolic, superoxide dismutase, ALS1, IPOA, homodimer
Source: HGNC:11179
Biotype: protein coding gene
para
(Drosophila melanogaster)Gene
Name: paralytic
Synonyms: Shudderer, bss, bangsenseless, DmNa[[v]]1, l(1)ESHS48, Paralytic, DmNav, bang senseless, Out cold, olfD, smell-blind, smellblind, Scn1alpha, bas, parabss, DmNav1, voltage-sensitive sodium channel, DmNa, CG9907, para13-5, DmNa[[v]], lincRNA.S9469, par, Shu, sbl-1, VSSC, Para, Nav1, Ocd, Out-cold, paralyzed, voltage gated sodium ion channel, l(1)14Da, sbl, DmNa[[V]], bang-senseless, bang sensitive
Source: FB:FBgn0285944
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: mechanistic target of rapamycin, rapamycin target protein 1, rapamycin and FKBP12 target 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FKBP12-rapamycin complex-associated protein 1, FRAP2, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, SKS, FRAP, serine/threonine-protein kinase mTOR, RAPT1, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
Tlr4
(Mus musculus)Gene
Name: toll-like receptor 4
Synonyms: lipopolysaccharide response, RAS-like, family 2, locus 8, Rasl2-8, Lps
Source: MGI:96824
Biotype: protein coding gene
Tgfb1
(Mus musculus)Gene
Name: transforming growth factor, beta 1
Synonyms: Tgfb-1, TGF-beta 1, Tgfb, TGFbeta1, TGF-beta1
Source: MGI:98725
Biotype: protein coding gene
HLA-DRB1
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 1
Synonyms: MHC class II HLA-DRw10-beta, HLA-DRB1*, leucocyte antigen DRB1, DW2.2/DR2.2, FLJ76359, HLA-DR-beta 1, leucocyte antigen DR beta 1 chain, MHC class II antigen, major histocompatibility complex, class II, DR beta 1 precursor, DRw8, SS1, DR16, DR-8, MHC class II HLA-DR beta 1 chain, lymphocyte antigen DRB1, DRB1, DR-16, HLA class II histocompatibility antigen, DR-1 beta chain, DR1, MHC class II antigen HLA-DR13, DR5, FLJ75017, HLA class II antigen beta chain, DR8, DRw11, DRw10, MHC class II HLA-DR-beta cell surface glycoprotein, human leucocyte antigen DRB1, HLA-DR1B, HLA-DRB
Source: HGNC:4948
Biotype: protein coding gene
pax6a
(Danio rerio)Gene
Name: paired box 6a
Synonyms: paxzfa, fc20e07, Pax6.1, pax-a, wu:fc20e07, pax[zf-a], zfpax-6b, zfpax-6a, etID309716.25, pax6, cb280
Source: ZFIN:ZDB-GENE-990415-200
Biotype: protein coding gene
MTHFR
(Homo sapiens)Gene
Name: methylenetetrahydrofolate reductase
Synonyms: methylenetetrahydrofolate reductase (NAD(P)H), methylenetetrahydrofolate reductase (NADPH), 5,10-methylenetetrahydrofolate reductase (NADPH)
Source: HGNC:7436
Biotype: protein coding gene
myo-3
(Caenorhabditis elegans)Gene
Name: MYOsin heavy chain structural genes 3
Synonyms: CELE_K12F2.1, K12F2.1, sup-3
Source: WB:WBGene00003515
Biotype: protein coding gene
MIP1
(Saccharomyces cerevisiae)Gene
Name: MItochondrial DNA Polymerase
Synonyms: YOR330C
Source: SGD:S000005857
Biotype: protein coding gene
VCP
(Homo sapiens)Gene
Name: valosin containing protein
Synonyms: epididymis secretory protein Li 70, IBMPFD, valosin-containing protein, HEL-S-70, MGC148092, CMT2Y, TERA, FTDALS6, transitional endoplasmic reticulum ATPase, yeast Cdc48p homolog, p97, 15S Mg(2+)-ATPase p97 subunit, HEL-220, MGC8560, TER ATPase, CDC48, MGC131997, ALS14, IBMPFD1, epididymis luminal protein 220
Source: HGNC:12666
Biotype: protein coding gene
Ifng
(Mus musculus)Gene
Name: interferon gamma
Synonyms: If2f, IFN-gamma, IFNG2, Ifg
Source: MGI:107656
Biotype: protein coding gene
let-23
(Caenorhabditis elegans)Gene
Name: LEThal 23
Synonyms: CELE_ZK1067.1, ZK1067.1, kin-7
Source: WB:WBGene00002299
Biotype: protein coding gene
SOD1
(Saccharomyces cerevisiae)Gene
Name: SuperOxide Dismutase
Synonyms: YJR104C, CRS4
Source: SGD:S000003865
Biotype: protein coding gene
ttr
(Danio rerio)Gene
Name: transthyretin (prealbumin, amyloidosis type I)
Synonyms: zgc:103583
Source: ZFIN:ZDB-GENE-040927-14
Biotype: protein coding gene
Casp3
(Mus musculus)Gene
Name: caspase 3
Synonyms: RIKEN cDNA A830040C14 gene, Apopain, melody, CC3, A830040C14Rik, Yama, AC-3, CPP32, mldy, CPP32-beta, Lice, Caspase-3
Source: MGI:107739
Biotype: protein coding gene
Ptgs2
(Mus musculus)Gene
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX-2, Cox-2, PHS II, Cox2, Pghs2, cyclooxygenase-2, prostaglandin G/H synthase, PHS-2, COX2, PGHS-2, cyclooxygenase 2, Tis10
Source: MGI:97798
Biotype: protein coding gene
Nlg2
(Drosophila melanogaster)Gene
Name: Neuroligin 2
Synonyms: neuroligin 2, Nlg-2, nl2, CG13772, dnlg2, Neuroligin, nlg2, Dnlg2, DNlg2, neuroligin, dnl2
Source: FB:FBgn0031866
Biotype: protein coding gene
Cav1
(Mus musculus)Gene
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1, Cav
Source: MGI:102709
Biotype: protein coding gene
H2-Ab1
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen A, beta 1
Synonyms: Bb, expressed sequence AI845868, response to metastatic cancers 1, H-2Ab, RT1.B, H2-Ab, histocompatibility 2, class II antigen A, beta, IAb, Rmcs1, I-region-associated antigen 2, I-A, AI845868, A beta, Abeta, Ia2, I-Abeta, Ia-2
Source: MGI:103070
Biotype: protein coding gene
Bdnf
(Mus musculus)Gene
Name: brain derived neurotrophic factor
Synonyms: Not Available
Source: MGI:88145
Biotype: protein coding gene
ACE
(Homo sapiens)Gene
Name: angiotensin I converting enzyme
Synonyms: CD143, dipeptidyl carboxypeptidase I, CD143 antigen, angiotensin 1 converting enzyme 1, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, testicular ECA, MGC26566, MVCD3, kininase II, peptidase P, ICH, DCP, ACE1, carboxycathepsin, dipeptidyl carboxypeptidase 1, angiotensin converting enzyme, somatic isoform, angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript, DCP1, angiotensin-converting enzyme
Source: HGNC:2707
Biotype: protein coding gene
IL10
(Homo sapiens)Gene
Name: interleukin 10
Synonyms: CSIF, MGC126450, MGC126451, TGIF, GVHDS, IL10A, T-cell growth inhibitory factor, cytokine synthesis inhibitory factor, interleukin-10, IL-10
Source: HGNC:5962
Biotype: protein coding gene
Ahr
(Mus musculus)Gene
Name: aryl-hydrocarbon receptor
Synonyms: Ahh, dioxin receptor, bHLHe76, Ahre, In, Ah, aryl hydrocarbon hydroxylase, inflammatory reactivity, aromatic hydrocarbon responsiveness
Source: MGI:105043
Biotype: protein coding gene
H2-Eb1
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen E beta
Synonyms: H-2Eb, Db1, I region-associated antigen 4, RT1-Db, RT1-Db1n, Ia-4, Ia4
Source: MGI:95901
Biotype: protein coding gene
BMP4
(Homo sapiens)Gene
Name: bone morphogenetic protein 4
Synonyms: MCOPS6, bone morphogenetic protein 2B, bone morphogenetic protein 4 preproprotein, BMP2B, OFC11, BMP-2B, BMP-4, ZYME, BMP2B1
Source: HGNC:1071
Biotype: protein coding gene