Version: 8.0.0Date: Tue Jan 28 2025
Gene Diseases: Huntington's disease
htt
(Drosophila melanogaster)Gene
Name: huntingtin
Synonyms: Huntingtin, CG9995, Htt, HTT, dHtt, dhtt, HD, DmHtt
Source: FB:FBgn0027655
Biotype: protein coding gene
HTT
(Homo sapiens)Gene
Name: huntingtin
Synonyms: LOMARS, huntington disease protein, HD, IT15, huntington disease gene homolog
Source: HGNC:4851
Biotype: protein coding gene
BCL2
(Homo sapiens)Gene
Name: BCL2 apoptosis regulator
Synonyms: Bcl-2, protein phosphatase 1, regulatory subunit 50, Bcl-2a, B-cell CLL/lymphoma 2, PPP1R50, Bcl-2ß, apoptosis regulator Bcl-2, b-cell leukemia/lymphoma 2, BCL2, apoptosis regulator
Source: HGNC:990
Biotype: protein coding gene
Htt
(Mus musculus)Gene
Name: huntingtin
Synonyms: C430023I11Rik, Huntington disease (human), expressed sequence AI256365, Huntington disease gene homolog, RIKEN cDNA C430023I11 gene, htt, Hd, HD, IT15, Hdh, AI256365
Source: MGI:96067
Biotype: protein coding gene
SIRT1
(Homo sapiens)Gene
Name: sirtuin 1
Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, regulatory protein SIR2 homolog 1, hSIRT1, hSIR2, sirtuin type 1, NAD-dependent deacetylase sirtuin-1
Source: HGNC:14929
Biotype: protein coding gene
HSF1
(Saccharomyces cerevisiae)Gene
Name: Heat Shock transcription Factor
Synonyms: YGL073W, EXA3, MAS3
Source: SGD:S000003041
Biotype: protein coding gene
Ptgs2
(Mus musculus)Gene
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX-2, Cox-2, PHS II, Cox2, Pghs2, cyclooxygenase-2, prostaglandin G/H synthase, PHS-2, COX2, PGHS-2, cyclooxygenase 2, Tis10
Source: MGI:97798
Biotype: protein coding gene
SNF1
(Saccharomyces cerevisiae)Gene
Name: Sucrose NonFermenting
Synonyms: CCR1, PAS14, CAT1, GLC2, HAF3, YDR477W
Source: SGD:S000002885
Biotype: protein coding gene
Bdnf
(Mus musculus)Gene
Name: brain derived neurotrophic factor
Synonyms: Not Available
Source: MGI:88145
Biotype: protein coding gene
LEP
(Homo sapiens)Gene
Name: leptin
Synonyms: OBS, obesity factor, OB, leptin (obesity homolog, mouse), obese protein, obese, mouse, homolog of, FLJ94114, leptin (murine obesity homolog), LEPD
Source: HGNC:6553
Biotype: protein coding gene
AGTR1
(Homo sapiens)Gene
Name: angiotensin II receptor type 1
Synonyms: AT2R1A, angiotensin receptor 1, angiotensin II receptor, type 1, AT2R1, AT2R1B, type-1 angiotensin II receptor, HAT1R, AT1R, ATR1, AGTR1A, angiotensin receptor 1B, AT1 receptor, AGTR1B, type-1B angiotensin II receptor, AT1BR, AT1AR, AG2S, angiotensin II type-1 receptor, AT1B, AT1
Source: HGNC:336
Biotype: protein coding gene
Casp3
(Mus musculus)Gene
Name: caspase 3
Synonyms: RIKEN cDNA A830040C14 gene, Apopain, melody, CC3, A830040C14Rik, Yama, AC-3, CPP32, mldy, CPP32-beta, Lice, Caspase-3
Source: MGI:107739
Biotype: protein coding gene
Lep
(Mus musculus)Gene
Name: leptin
Synonyms: ob, OB, obese
Source: MGI:104663
Biotype: protein coding gene
Bax
(Mus musculus)Gene
Name: BCL2-associated X protein
Synonyms: Not Available
Source: MGI:99702
Biotype: protein coding gene
F2
(Homo sapiens)Gene
Name: coagulation factor II, thrombin
Synonyms: thrombin factor II, RPRGL2, prothrombin B-chain, THPH1, PT, prepro-coagulation factor II, coagulation factor II, serine protease, coagulation factor II (thrombin), prothrombin
Source: HGNC:3535
Biotype: protein coding gene
Drd1
(Mus musculus)Gene
Name: dopamine receptor D1
Synonyms: dopamine receptor D1A, RIKEN cDNA C030036C15 gene, D1 receptor, Drd1a, D1a, C030036C15Rik, dopamine receptor 1, Drd-1, G-protein coupled receptor 15, Gpcr15
Source: MGI:99578
Biotype: protein coding gene
Drice
(Drosophila melanogaster)Gene
Name: Death related ICE-like caspase
Synonyms: interleukin-1beta-converting enzyme, ice, ICE, Ice, drICE, caspase 3, drIce, drice, DriCE, DrICE, DrIce, Drice, CG7788, crice, DRICE, Drive, caspase-3
Source: FB:FBgn0019972
Biotype: protein coding gene
Pls3
(Mus musculus)Gene
Name: plastin 3 (T-isoform)
Synonyms: AI115446, T-fimbrin, expressed sequence AL024105, AL024105, expressed sequence AI115446
Source: MGI:104807
Biotype: protein coding gene
Sirt1
(Mus musculus)Gene
Name: sirtuin 1
Synonyms: Sir2, expressed sequence AA673258, AA673258, Sir2alpha
Source: MGI:2135607
Biotype: protein coding gene
Il6
(Mus musculus)Gene
Name: interleukin 6
Synonyms: ILg6, Ifnb2, Il-6
Source: MGI:96559
Biotype: protein coding gene
skn-1
(Caenorhabditis elegans)Gene
Name: SKiNhead 1
Synonyms: xrep-3, CELE_T19E7.2, sow-1, skinhead 1, T19E7.2
Source: WB:WBGene00004804
Biotype: protein coding gene
BDNF
(Homo sapiens)Gene
Name: brain derived neurotrophic factor
Synonyms: BULN2, abrineurin, MGC34632, brain-derived neurotrophic factor, neurotrophin, ANON2
Source: HGNC:1033
Biotype: protein coding gene
Hnmt
(Mus musculus)Gene
Name: histamine N-methyltransferase
Synonyms: RIKEN cDNA 1500031F01 gene, expressed sequence AI788969, AI788969, 1500031F01Rik
Source: MGI:2153181
Biotype: protein coding gene
Tfam
(Mus musculus)Gene
Name: transcription factor A, mitochondrial
Synonyms: AI661103, high mobility group protein, testis specific, Hmgts, Mttfa, tsHMG, mtTFA, expressed sequence AI661103
Source: MGI:107810
Biotype: protein coding gene
Mbp
(Mus musculus)Gene
Name: myelin basic protein
Synonyms: mld, expressed sequence C76307, C76307, R75289, shi, shiverer, expressed sequence R75289, Hmbpr, jve, golli-mbp, Mbps, hemopoietic myelin basic protein related, myelin deficient, jive
Source: MGI:96925
Biotype: protein coding gene
Ppargc1a
(Mus musculus)Gene
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Synonyms: Pgc1, Pgc-1alpha, PGCvf-1, ENSMUSG00000079510, A830037N07Rik, predicted gene, ENSMUSG00000079510, PGC-1v, Gm11133, PPAR Gamma Coactivator-1, LRPGC1, PGCvf, PPAR gamma coactivator 1, PGCvf1, Ppargc1, Pgco1, predicted gene 11133, RIKEN cDNA A830037N07 gene, Pgc-1alphaa
Source: MGI:1342774
Biotype: protein coding gene
Spn
(Drosophila melanogaster)Gene
Name: Spinophilin
Synonyms: E62, spn, l(3)06911, d-spinophilin, EL62, BcDNA:GM16129, CG16757, SPINOPHILIN, c62E-5
Source: FB:FBgn0010905
Biotype: protein coding gene
Foxp1
(Mus musculus)Gene
Name: forkhead box P1
Synonyms: 3110052D19Rik, 4932443N09Rik, RIKEN cDNA 3110052D19 gene, expressed sequence AW494214, AW494214, RIKEN cDNA 4932443N09 gene
Source: MGI:1914004
Biotype: protein coding gene
Il6ra
(Mus musculus)Gene
Name: interleukin 6 receptor, alpha
Synonyms: IL-6R, IL6R1, interleukin 6 receptor, CD126, Il6r, IL-6 receptor alpha chain
Source: MGI:105304
Biotype: protein coding gene
CYCS
(Homo sapiens)Gene
Name: cytochrome c, somatic
Synonyms: THC4, HCS, cytochrome c, CYC
Source: HGNC:19986
Biotype: protein coding gene
COX2
(Saccharomyces cerevisiae)Gene
Name: Cytochrome c OXidase
Synonyms: Q0250, OXI1, OXII
Source: SGD:S000007281
Biotype: protein coding gene
NFE2L2
(Homo sapiens)Gene
Name: NFE2 like bZIP transcription factor 2
Synonyms: HEBP1, NRF2, nuclear factor (erythroid-derived 2)-like 2, nuclear factor, erythroid derived 2, like 2, Nrf-2, nuclear factor, erythroid 2 like 2, NF-E2-related factor 2, IMDDHH, nuclear factor, erythroid 2-like 2, nuclear factor erythroid 2-related factor 2, NFE2-related factor 2, nuclear factor erythroid-derived 2-like 2
Source: HGNC:7782
Biotype: protein coding gene
Glul
(Mus musculus)Gene
Name: glutamate-ammonia ligase
Synonyms: glutamine synthetase, Glns, GS
Source: MGI:95739
Biotype: protein coding gene
Gsr
(Mus musculus)Gene
Name: glutathione reductase
Synonyms: D8Ertd238e, Gr1, DNA segment, Chr 8, ERATO Doi 238, expressed, expressed sequence AI325518, AI325518, Gr-1
Source: MGI:95804
Biotype: protein coding gene
Fas
(Mus musculus)Gene
Name: Fas cell surface death receptor
Synonyms: Fas (TNF receptor superfamily member 6), AI196731, CD95, TNFR6, TNF receptor superfamily member 6, expressed sequence AI196731, lymphoproliferation, FasR, APO-1, Tnfrsf6, lpr
Source: MGI:95484
Biotype: protein coding gene
Haao
(Mus musculus)Gene
Name: 3-hydroxyanthranilate 3,4-dioxygenase
Synonyms: RIKEN cDNA 0610007K21 gene, 0610007K21Rik, 3-HAOxase, 3-HAO, 3HAO, 0610012J07Rik, RIKEN cDNA 0610012J07 gene
Source: MGI:1349444
Biotype: protein coding gene
Gss
(Mus musculus)Gene
Name: glutathione synthetase
Synonyms: GS-A/GS-B, AI314904, expressed sequence AI314904
Source: MGI:95852
Biotype: protein coding gene
crh-1
(Caenorhabditis elegans)Gene
Name: CREB Homolog 1
Synonyms: CELE_Y41C4A.4, Y41C4A.4
Source: WB:WBGene00000793
Biotype: protein coding gene
Ppp1r9a
(Mus musculus)Gene
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: Neb1, 4930518N04Rik, RIKEN cDNA 2810430P21 gene, expressed sequence BB181831, p180, neurabin-I, Neurabin I, mKIAA1222, A230094E16Rik, PP1bp175, RIKEN cDNA A230094E16 gene, RIKEN cDNA 4930518N04 gene, 2810430P21Rik, BB181831, NRB
Source: MGI:2442401
Biotype: protein coding gene
Parp1
(Mus musculus)Gene
Name: poly (ADP-ribose) polymerase family, member 1
Synonyms: poly (ADP-ribose) polymerase, Adprt1, Parp-1, expressed sequence AI893648, Adprp, PARP, ARTD1, sPARP-1, Adprt, AI893648, RIKEN cDNA 5830444G22 gene, parp-1, 5830444G22Rik, C80510, expressed sequence C80510, ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1
Source: MGI:1340806
Biotype: protein coding gene
Slc1a2
(Mus musculus)Gene
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Synonyms: GLT1, expressed sequence AI159670, Glt-1, 2900019G14Rik, excitatory amino acid transporter 2, RIKEN cDNA 2900019G14 gene, RIKEN cDNA 1700091C19 gene, Glt, MGLT1, AI159670, 1700091C19Rik, Eaat2, GLT-1
Source: MGI:101931
Biotype: protein coding gene
PPARGC1A
(Homo sapiens)Gene
Name: PPARG coactivator 1 alpha
Synonyms: PPAR gamma coactivator-1, L-PGC-1alpha, PPAR gamma coactivator variant form, PPAR-gamma coactivator 1-alpha, peroxisome proliferator-activated receptor gamma, coactivator 1 alpha, peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4, peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5, PGC-1(alpha), PGC1A, PGC-1-alpha, PPARGC-1-alpha, peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a, PGC1, LEM6, peroxisome proliferative activated receptor, gamma, coactivator 1, alpha, PPARgamma coactivator 1alpha, ligand effect modulator 6, PGC-1v, peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1alpha, PPARGC1, PPARAGCIalpha, peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT, peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext, ligand effect modulator-6
Source: HGNC:9237
Biotype: protein coding gene
CAT
(Homo sapiens)Gene
Name: catalase
Synonyms: MGC138422, MGC138424
Source: HGNC:1516
Biotype: protein coding gene
FAS
(Homo sapiens)Gene
Name: Fas cell surface death receptor
Synonyms: Fas antigen, TNF receptor superfamily member 6, FASTM, apoptosis-mediating surface antigen FAS, FAS receptor variant 9, APO-1 cell surface antigen, apoptosis antigen 1, APT1, Delta Fas/APO-1/CD95, Fas (TNF receptor superfamily, member 6), mutant tumor necrosis receptor superfamily member 6, FAS1, TNFRSF6, APO-1, FAS 827dupA, ALPS1A, CD95, CD95 antigen, apo-1 antigen, FASLG receptor, apoptosis signaling receptor FAS, Fas AMA, RP11-399O19.9, tumor necrosis factor receptor superfamily, member 6, tumor necrosis factor receptor superfamily member 6
Source: HGNC:11920
Biotype: protein coding gene
Nfe2l2
(Mus musculus)Gene
Name: nuclear factor, erythroid derived 2, like 2
Synonyms: expressed sequence AI194320, AI194320, Nrf2
Source: MGI:108420
Biotype: protein coding gene
NPL3
(Saccharomyces cerevisiae)Gene
Name: Nuclear Protein Localization
Synonyms: NOP3, MTS1, NAB1, MTR13, YDR432W
Source: SGD:S000002840
Biotype: protein coding gene
Pacsin1
(Mus musculus)Gene
Name: protein kinase C and casein kinase substrate in neurons 1
Synonyms: Syndapin I, mKIAA1379, A830061D09Rik, RIKEN cDNA A830061D09 gene
Source: MGI:1345181
Biotype: protein coding gene
Tbp
(Drosophila melanogaster)Gene
Name: TATA binding protein
Synonyms: RBP, TATA-box binding protein, tbp, TBP, TATA box binding protein, TATA-Binding Protein, dTFIID, dTbp, dTBP, 42kDa polypeptide, dtbp, TATA box-binding protein, TFIID, TATA-binding protein, CG9874, TFIIDtau, TBP38, TfIID
Source: FB:FBgn0003687
Biotype: protein coding gene
SIR2
(Saccharomyces cerevisiae)Gene
Name: Silent Information Regulator
Synonyms: MAR1, YDL042C
Source: SGD:S000002200
Biotype: protein coding gene
PDE2
(Saccharomyces cerevisiae)Gene
Name: PhosphoDiEsterase
Synonyms: SRA5, YOR360C
Source: SGD:S000005887
Biotype: protein coding gene