Version: 8.0.0Date: Tue Jan 28 2025
Gene Diseases: asthma
H2-K1
(Mus musculus)Gene
Name: histocompatibility 2, K1, K region
Synonyms: RT1-A2n, RT1-CE12, rt1-El, RT1-A, RT1-CE7, RT1-E2, RT1A-1, RT1A-2, RT1-C/E1, RT1-C/E5, RT1.A2(N), RT1-C/E3, RT1-C/E4, RT1.A1(N), RT1-A1n, RT1-C/E7, H-2K
Source: MGI:95904
Biotype: protein coding gene
EGFR
(Homo sapiens)Gene
Name: epidermal growth factor receptor
Synonyms: PIG61, NNCIS, receptor tyrosine-protein kinase erbB-1, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), erythroblastic leukemia viral (v-erb-b) oncogene homolog, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, NISBD2, HER1
Source: HGNC:3236
Biotype: protein coding gene
CFTR
(Homo sapiens)Gene
Name: CF transmembrane conductance regulator
Synonyms: CF, ABCC7, cystic fibrosis transmembrane conductance regulator, atp-binding cassette (sub-family c, member 7), MRP7, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7, dJ760C5.1, ATP-binding cassette sub-family C member 7, ABC35, cystic fibrosis transmembrane conductance regulator, TNR-CFTR, cystic fibrosis transmembrane conductance regulating, channel conductance-controlling ATPase, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Source: HGNC:1884
Biotype: protein coding gene
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
Mpo
(Mus musculus)Gene
Name: myeloperoxidase
Synonyms: Not Available
Source: MGI:97137
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
HLA-B
(Homo sapiens)Gene
Name: major histocompatibility complex, class I, B
Synonyms: Bw-45, MHC HLA-B27-HS, HLA-B39, Bw-47, Bw-48, MHC Class I HLA heavy chain, HLAB, HLAC, MHC class I antigen B*46, HLA class I histocompatibility antigen, B-73 alpha chain, MHC class I antigen B*45, MHC class I antigen B*44, HLA-Bw45 antigen, MHC class II antigen, HLA-B*45ZJ, MHC class I antigen B*49, HLA-B35, MHC class I antigen B*48, MHC class I antigen B*47, MHC class I antigen HLA-B heavy chain, MHC class I antigen B*42, MHC class I antigen B*41, MGC111087, MHC class I antigen B*40, HLA B-40011, HLA-B alpha chain (B*5002), MHC class I antigen B*7, Bw-56, MHC class I antigen B*8, Bw-58, bw-22, HLA class I histocompatibility antigen, B-5 alpha chain, MHC class I antigen B*57, HLA-C, MHC class I antigen B*56, MHC HLA-B cell surface glycoprotein, MHC class I antigen B*55, Bw-50, HLA class I histocompatibility antigen, B-8 alpha chain, MHC class I antigen B*54, HLA-B49, MHC class I antigen B*59, MHC class I antigen B*58, HLA class I histocompatibility antigen, B-7 alpha chain, AS, MHC class I antigen B*53, MHC class I antigen B*52, MHC class I antigen B*51, MHC class I antigen B*50, HLA-Bw50 antigen, HLA class I histocompatibility antigen, B-67 alpha chain, HLA class I histocompatibility antigen, B-45 alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA molecule, ankylosing spondylitis, HLA-B55, MHC class I antigen B*67, HLA-B-7301, HLA B44, HLA-B59, HLA class I histocompatibility antigen, B-48 alpha chain, MHC class I antigen Cw*5, HLA-B50, HLA class I histocompatibility antigen, B-21 alpha chain, HEL-S-83, SPDA1, bw-46, bw-44, HLA-B-3905, MHC class I antigen B*78, HLA-B-3506, bw-41, MHC class l antigen, HLA class I histocompatibility antigen, B-82 alpha chain, MHC class I antigen B*73, HLA-B alpha chain (HLA-B*7301), HLA-B61, b'DT, MHC class 1 antigen, lecocyte antigen B, HLA-DRB1, bw-57, HLA class I histocompatibility antigen, B-56 alpha chain, bw-55, histocompatibility antigen, bw-54, bw-53, HLA-B-5502, bw-52, HLA-Cw, Leukocyte Antigen, HLA class I histocompatibility antigen, B-59 alpha chain, MHC class I antigen B*82, MHC class I antigen B*81, HLA-B*5901 antigen, bw-4, MHC antigen, truncated MHC class I antigen, HLA-B73, MHC class I antigen GN00104, HLA class I histocompatibility antigen, B-12 alpha chain, epididymis secretory protein Li 83, MHC class I antigen B*18, MHC class I antigen B*13, bw-60, HLA class I antigen HLA-B, MHC class I antigen B*15, MHC class I antigen B*14, class I MHC, HLA-B antigen, truncated class I antigen, B-5001, MHC HLA-B transmembrane glycoprotein, MHC class I human leukocyte antigen, MHC class I molecule, MHC class I antigene, B-4901, Leukoocyte Antigen, HLA-B15, MHC class I antigen B*27, HLA-B-5601, HLA-B-5602, HLA -B, leukocyte antigen class I-B, HLA-B35 antigen, HLA class I histocompatibility antigen, Cw-5 alpha chain, MHC HLA-B27d, HLA-B alpha chain, HLA-B alpha-chain, major histocompatability complex B antigen, MHC class I antigen SHCHA, MHC class I antigen B*35, HLA class I histocompatibility antigen, B alpha chain, MHC class I alpha chain, MHC class I antigen B*39, HLA-B-6701, HLA-B alpha chain (B*2706), HLA-B27, MHC class I antigen B*38, MHC class I antigen B*37, MHC classI antigen, HLA class I histocompatibility antigen, B-50 alpha chain, HLA locus, MHC class I antigen HLA-B alpha chain, MHC HLA-B39N, MHC class I anitgen, lymphocyte antigen
Source: HGNC:4932
Biotype: protein coding gene
Tlr4
(Mus musculus)Gene
Name: toll-like receptor 4
Synonyms: lipopolysaccharide response, RAS-like, family 2, locus 8, Rasl2-8, Lps
Source: MGI:96824
Biotype: protein coding gene
Tgfb1
(Mus musculus)Gene
Name: transforming growth factor, beta 1
Synonyms: Tgfb-1, TGF-beta 1, Tgfb, TGFbeta1, TGF-beta1
Source: MGI:98725
Biotype: protein coding gene
HLA-DRB1
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 1
Synonyms: MHC class II HLA-DRw10-beta, HLA-DRB1*, leucocyte antigen DRB1, DW2.2/DR2.2, FLJ76359, HLA-DR-beta 1, leucocyte antigen DR beta 1 chain, MHC class II antigen, major histocompatibility complex, class II, DR beta 1 precursor, DRw8, SS1, DR16, DR-8, MHC class II HLA-DR beta 1 chain, lymphocyte antigen DRB1, DRB1, DR-16, HLA class II histocompatibility antigen, DR-1 beta chain, DR1, MHC class II antigen HLA-DR13, DR5, FLJ75017, HLA class II antigen beta chain, DR8, DRw11, DRw10, MHC class II HLA-DR-beta cell surface glycoprotein, human leucocyte antigen DRB1, HLA-DR1B, HLA-DRB
Source: HGNC:4948
Biotype: protein coding gene
MTHFR
(Homo sapiens)Gene
Name: methylenetetrahydrofolate reductase
Synonyms: methylenetetrahydrofolate reductase (NAD(P)H), methylenetetrahydrofolate reductase (NADPH), 5,10-methylenetetrahydrofolate reductase (NADPH)
Source: HGNC:7436
Biotype: protein coding gene
ACE
(Homo sapiens)Gene
Name: angiotensin I converting enzyme
Synonyms: CD143, dipeptidyl carboxypeptidase I, CD143 antigen, angiotensin 1 converting enzyme 1, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, testicular ECA, MGC26566, MVCD3, kininase II, peptidase P, ICH, DCP, ACE1, carboxycathepsin, dipeptidyl carboxypeptidase 1, angiotensin converting enzyme, somatic isoform, angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript, DCP1, angiotensin-converting enzyme
Source: HGNC:2707
Biotype: protein coding gene
IL10
(Homo sapiens)Gene
Name: interleukin 10
Synonyms: CSIF, MGC126450, MGC126451, TGIF, GVHDS, IL10A, T-cell growth inhibitory factor, cytokine synthesis inhibitory factor, interleukin-10, IL-10
Source: HGNC:5962
Biotype: protein coding gene
Ptgs2
(Mus musculus)Gene
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX-2, Cox-2, PHS II, Cox2, Pghs2, cyclooxygenase-2, prostaglandin G/H synthase, PHS-2, COX2, PGHS-2, cyclooxygenase 2, Tis10
Source: MGI:97798
Biotype: protein coding gene
Cftr
(Mus musculus)Gene
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7, expressed sequence AW495489, AW495489, RGD1561193
Source: MGI:88388
Biotype: protein coding gene
Ifng
(Mus musculus)Gene
Name: interferon gamma
Synonyms: If2f, IFN-gamma, IFNG2, Ifg
Source: MGI:107656
Biotype: protein coding gene
ABCB1
(Homo sapiens)Gene
Name: ATP binding cassette subfamily B member 1
Synonyms: P-GP, ATP-binding cassette, sub-family B (MDR/TAP), member 1, CLCS, ATP-binding cassette sub-family B member 1, ENPAT, PGY1, multidrug resistance protein 1, ATP-binding cassette, subfamily B, member 1, GP170, colchicin sensitivity, ATP-dependent translocase ABCB1, p-170, MDR1, ABC20, MGC163296, P-glycoprotein 1, P glycoprotein, phospholipid transporter ABCB1, doxorubicin resistance, CD243
Source: HGNC:40
Biotype: protein coding gene
let-23
(Caenorhabditis elegans)Gene
Name: LEThal 23
Synonyms: CELE_ZK1067.1, ZK1067.1, kin-7
Source: WB:WBGene00002299
Biotype: protein coding gene
H2-Aa
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen A, alpha
Synonyms: BA1, I-Aalpha, histocompatibility 2, class II antigen A alpha, H-2Aa, A alpha, Ia1, Aalpha, I region-associated antigen 1, Ia-1
Source: MGI:95895
Biotype: protein coding gene
CDH1
(Homo sapiens)Gene
Name: cadherin 1
Synonyms: BCDS1, LCAM, calcium-dependent adhesion protein, epithelial, cell-CAM 120/80, ECAD, CDHE, cadherin 1, E-cadherin (epithelial), CAM 120/80, UVO, uvomorulin, cadherin 1, type 1, E-cadherin (epithelial), E-cadherin 1, cadherin 1, type 1, E-Cadherin, CD324, cadherin-1, epithelial cadherin, Arc-1, truncated cadherin 1 type 1
Source: HGNC:1748
Biotype: protein coding gene
H2-Ab1
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen A, beta 1
Synonyms: Bb, expressed sequence AI845868, response to metastatic cancers 1, H-2Ab, RT1.B, H2-Ab, histocompatibility 2, class II antigen A, beta, IAb, Rmcs1, I-region-associated antigen 2, I-A, AI845868, A beta, Abeta, Ia2, I-Abeta, Ia-2
Source: MGI:103070
Biotype: protein coding gene
Slc6a4
(Mus musculus)Gene
Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Synonyms: 5-HTT, 5-hydroxytryptamine (serotonin) transporter, SERT, Sert, Htt, AI323329, expressed sequence AI323329
Source: MGI:96285
Biotype: protein coding gene
Bdnf
(Mus musculus)Gene
Name: brain derived neurotrophic factor
Synonyms: Not Available
Source: MGI:88145
Biotype: protein coding gene
FAA1
(Saccharomyces cerevisiae)Gene
Name: Fatty Acid Activation
Synonyms: YOR317W
Source: SGD:S000005844
Biotype: protein coding gene
LEP
(Homo sapiens)Gene
Name: leptin
Synonyms: OBS, obesity factor, OB, leptin (obesity homolog, mouse), obese protein, obese, mouse, homolog of, FLJ94114, leptin (murine obesity homolog), LEPD
Source: HGNC:6553
Biotype: protein coding gene
AGTR1
(Homo sapiens)Gene
Name: angiotensin II receptor type 1
Synonyms: AT2R1A, angiotensin receptor 1, angiotensin II receptor, type 1, AT2R1, AT2R1B, type-1 angiotensin II receptor, HAT1R, AT1R, ATR1, AGTR1A, angiotensin receptor 1B, AT1 receptor, AGTR1B, type-1B angiotensin II receptor, AT1BR, AT1AR, AG2S, angiotensin II type-1 receptor, AT1B, AT1
Source: HGNC:336
Biotype: protein coding gene
se
(Drosophila melanogaster)Gene
Name: sepia
Synonyms: dmgsto1, GSTO4, sepia, Se, PDAS, DmGSTO4, pyrimidodiazepine synthase, GSTO1, Sepia, CG6781, cg6781
Source: FB:FBgn0086348
Biotype: protein coding gene
HLA-DQB1
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DQ beta 1
Synonyms: MHC class2 antigen, CELIAC1, IDDM1, HLA class II histocompatibility antigen, DQ beta 1 chain, MHC class II DQ beta chain, MHC class II antigen DQB1, MHC class II antigen HLA-DQ-beta-1, MHC DQ beta, lymphocyte antigen, HLA class II antigen, MHC class II HLA-DQ beta glycoprotein, major histocompatibility complex class II beta, HLA-DRB1, HLA-DQB
Source: HGNC:4944
Biotype: protein coding gene
Lep
(Mus musculus)Gene
Name: leptin
Synonyms: ob, OB, obese
Source: MGI:104663
Biotype: protein coding gene
H2-Eb1
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen E beta
Synonyms: H-2Eb, Db1, I region-associated antigen 4, RT1-Db, RT1-Db1n, Ia-4, Ia4
Source: MGI:95901
Biotype: protein coding gene
Foxp3
(Mus musculus)Gene
Name: forkhead box P3
Synonyms: RGD1562112, sf, scurfy, scurfin, JM2
Source: MGI:1891436
Biotype: protein coding gene
Il1b
(Mus musculus)Gene
Name: interleukin 1 beta
Synonyms: IL-1F2, IL-1B, IL-1beta, Il-1b
Source: MGI:96543
Biotype: protein coding gene
H2-Q6
(Mus musculus)Gene
Name: histocompatibility 2, Q region locus 6
Synonyms: RT1-A2n, RT1-CE12, Qa6, rt1-El, RT1-A, RT1-CE7, RT1-E2, Qa lymphocyte antigen 6, RT1A-1, RT1A-2, RT1-C/E1, RT1-C/E2, RT1-C/E5, H-2Q6, RT1.A2(N), RIKEN cDNA 0610037M15 gene, 0610037M15Rik, RT1-A1n, RT1.A1(N), RT1-C/E7, Qa-6
Source: MGI:95935
Biotype: protein coding gene
H2-D1
(Mus musculus)Gene
Name: histocompatibility 2, D region locus 1
Synonyms: RT1-A2n, RT1-CE12, rt1-El, RT1-CE7, RT1-A, RT1-E2, RT1A-1, RT1A-2, RT1-C/E1, H-2D, RT1-C/E5, RT1-C/E3, RT1.A2(N), RT1-C/E4, RT1-A1n, RT1.A1(N), RT1-C/E7
Source: MGI:95896
Biotype: protein coding gene
Adh5
(Mus musculus)Gene
Name: alcohol dehydrogenase 5 (class III), chi polypeptide
Synonyms: Adh3, S-nitrosoglutathione reductase, GSNOR, Adh-5
Source: MGI:87929
Biotype: protein coding gene
skn-1
(Caenorhabditis elegans)Gene
Name: SKiNhead 1
Synonyms: xrep-3, CELE_T19E7.2, sow-1, skinhead 1, T19E7.2
Source: WB:WBGene00004804
Biotype: protein coding gene
Fcgr2b
(Mus musculus)Gene
Name: Fc receptor, IgG, low affinity IIb
Synonyms: LyM-1, Fc[g]RII, RIKEN cDNA F630109E10 gene, lymphocyte antigen 17, Fcr-3, Fcr-2, AI528646, FcgRII, CD32, Ly-17, Fcgr2a, Fcgr2, Fc gamma RIIB, F630109E10Rik, Lym-1, Ly-m20, FcgammaRIIB2, expressed sequence AI528646, FCRII, lymphocyte antigen m20, Fc receptor, IgG, low affinity IIa, FcgammaRIIB, Fc-gamma receptor 2, Fc receptor, IgG, low affinity II, Fc-gamma receptor 3
Source: MGI:95499
Biotype: protein coding gene
Gata3
(Mus musculus)Gene
Name: GATA binding protein 3
Synonyms: juvenile alopecia, jal, Gata-3
Source: MGI:95663
Biotype: protein coding gene
H2-Q4
(Mus musculus)Gene
Name: histocompatibility 2, Q region locus 4
Synonyms: Qb1, H2-Gs10, RT1-A2n, Qb lymphocyte antigen 1, Qa4, rt1-El, Qat-4, RT1-A, RT1-CE7, RT1-E2, Qa-4, RT1A-1, MHC class I like protein GS10, Qa lymphocyte antigen 4, Qb-1, RT1A-2, RT1-C/E2, Qa T-cell antigen 4, RT1-C/E5, RT1.A2(N), H-2Q4, RT1.A1(N), RT1-A1n, RT1-C/E7
Source: MGI:95933
Biotype: protein coding gene
Ccl2
(Mus musculus)Gene
Name: C-C motif chemokine ligand 2
Synonyms: MCP-1, monocyte chemotactic protein, expressed sequence AI323594, small inducible gene JE, monocyte chemoattractant protein-1, small inducible cytokine A2, Sigje, MCP1, AI323594, SMC-CF, Scya2, HC11, MCAF
Source: MGI:98259
Biotype: protein coding gene
acn-1
(Caenorhabditis elegans)Gene
Name: ACE (angiotensin converting enzyme)-like Non-peptidase 1
Synonyms: C42D8.5, CELE_C42D8.5
Source: WB:WBGene00000039
Biotype: protein coding gene
Il6
(Mus musculus)Gene
Name: interleukin 6
Synonyms: ILg6, Ifnb2, Il-6
Source: MGI:96559
Biotype: protein coding gene
Hnmt
(Mus musculus)Gene
Name: histamine N-methyltransferase
Synonyms: RIKEN cDNA 1500031F01 gene, expressed sequence AI788969, AI788969, 1500031F01Rik
Source: MGI:2153181
Biotype: protein coding gene
Il10
(Mus musculus)Gene
Name: interleukin 10
Synonyms: IL10X, cytokine synthesis inhibitory factor, If2a, IL-10, Il-10
Source: MGI:96537
Biotype: protein coding gene
Stat92E
(Drosophila melanogaster)Gene
Name: Signal-transducer and activator of transcription protein at 92E
Synonyms: dSTAT92E/marelle, l(3)j6C8, D-stat, mrL, stat[92E], signal transducers and activator of transcription, STAT92, DmSTAT, signal transducer and activator of transcription, SD-stat, DRODSRC, Dstat92E, dstat, STAT92E, dSTAT, CG4257, Stat9E, stat92E, Stat, pSTAT, D-STAT, d-STAT, Stat92e, Dstat 92E, Stat1alpha-like, D-stat/stat92E, stat92, DSRC, stat, Signal-transducer and activator of transcription protein, Dst, Marelle, mrl, STAT 92E, Dstat, STAT92e, pSTAT92E, STAT, stat92e, D-Stat, dSTAT92E, Stat92E, mrl stat92E, marelle, DSTAT, l(3)06346, Sta92E, Stat92
Source: FB:FBgn0016917
Biotype: protein coding gene
SOD2
(Homo sapiens)Gene
Name: superoxide dismutase 2
Synonyms: superoxide dismutase [Mn], mitochondrial, MNSOD, GClnc1, mangano-superoxide dismutase, MVCD6, indophenoloxidase B, manganese-containing superoxide dismutase, superoxide dismutase 2, mitochondrial, GC1, Mn-SOD, Mn superoxide dismutase, IPO-B, IPOB, gastric cancer-associated lncRNA 1
Source: HGNC:11180
Biotype: protein coding gene
Ednrb
(Mus musculus)Gene
Name: endothelin receptor type B
Synonyms: expressed sequence AU022549, AU022549, ETb, Etb, s, Ednra, piebald, ETR-b, Sox10m1
Source: MGI:102720
Biotype: protein coding gene
CYP2D6
(Homo sapiens)Gene
Name: cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)
Synonyms: CPD6, CYP2D7BP, CYPIID6, P450C2D, microsomal monooxygenase, cytochrome P450 family 2 subfamily D member 6, cytochrome P450 2D6, CYP2D@, CYP2DL1, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2, MGC120390, cholesterol 25-hydroxylase, cytochrome p450 2d18, cytochrome P450, family 2, subfamily D, polypeptide 6, P450DB1, CYP2D7AP, debrisoquine 4-hydroxylase, cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2, P450-DB1, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6, nonfunctional cytochrome P450 2D6, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1, cytochrome P450-DB1, flavoprotein-linked monooxygenase, xenobiotic monooxygenase, cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2, MGC120389, CYP2D7P2, cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2, CYP2D8P2, CYP2D
Source: HGNC:2625
Biotype: protein coding gene
CAT2
(Saccharomyces cerevisiae)Gene
Name: Carnitine AcetylTransferase
Synonyms: YML042W, YCAT
Source: SGD:S000004506
Biotype: protein coding gene
F2
(Homo sapiens)Gene
Name: coagulation factor II, thrombin
Synonyms: thrombin factor II, RPRGL2, prothrombin B-chain, THPH1, PT, prepro-coagulation factor II, coagulation factor II, serine protease, coagulation factor II (thrombin), prothrombin
Source: HGNC:3535
Biotype: protein coding gene