Version: 8.0.0Date: Tue Jan 28 2025
Gene Diseases: cell type benign neoplasm
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Pten
(Mus musculus)Gene
Name: phosphatase and tensin homolog
Synonyms: B430203M17Rik, RIKEN cDNA B430203M17 gene, expressed sequence AI463227, RIKEN cDNA 2310035O07 gene, TEP1, Mmac, A130070J02Rik, MMAC1, AI463227, 2310035O07Rik, RIKEN cDNA A130070J02 gene
Source: MGI:109583
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
Bmp4
(Mus musculus)Gene
Name: bone morphogenetic protein 4
Synonyms: Bmp2b, bone morphogenetic protein 2b, BOMPR4A, Bmp2b-1, Bmp-4, bone morphogenetic protein 2b 1, Bmp2b1
Source: MGI:88180
Biotype: protein coding gene
BRAF
(Homo sapiens)Gene
Name: B-Raf proto-oncogene, serine/threonine kinase
Synonyms: serine/threonine-protein kinase B-raf, RAFB1, B-Raf serine/threonine-protein, B-RAF1, v-raf murine sarcoma viral oncogene homolog B1, v-raf murine sarcoma viral oncogene homolog B, p94, B-Raf proto-oncogene serine/threonine-protein kinase (p94), proto-oncogene B-Raf, MGC138284, MGC126806, NS7, B-raf, BRAF1, FLJ95109, 94 kDa B-raf protein, BRAF-1, murine sarcoma viral (v-raf) oncogene homolog B1
Source: HGNC:1097
Biotype: protein coding gene
PTEN
(Homo sapiens)Gene
Name: phosphatase and tensin homolog
Synonyms: MHAM, DEC, PTENepsilon, 10q23del, phosphatase and tensin-like protein, PTEN1, mitochondrial PTENalpha, GLM2, PTEN variant PTEN-K267Rfs*9, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, CWS1, mutated in multiple advanced cancers 1, MMAC1, PTEN variant PTEN-L247*, PTEN variant PTEN-R234Afs*11, mitochondrial phosphatase and tensin protein alpha, TEP1, PTENgama, inositol polyphosphate 3-phosphatase, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, BZS, PTENbeta, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MGC11227
Source: HGNC:9588
Biotype: protein coding gene
dpp
(Drosophila melanogaster)Gene
Name: decapentaplegic
Synonyms: shv, DPP, Dpp, ho, TGF-b, blink, M(2)23AB, DmDPP, l(2)10638, M(2)LS1, Decapentaplegic/Bone Morphogenetic Protein, Haplo-insufficient, TGF-beta, Tg, CG9885, DPP-C, TGFbeta, blk, Tegula, Hin-d, Bmp, BMP, Decapentaplegic, bone morphogenetic protein, l(2)22Fa, Tgfbeta, heldout, Dpp/TGFbeta, bone morphogenic protein, shortvein, l(2)k17036, Dm-DPP
Source: FB:FBgn0000490
Biotype: protein coding gene
MYC
(Homo sapiens)Gene
Name: MYC proto-oncogene, bHLH transcription factor
Synonyms: proto-oncogene c-Myc, avian myelocytomatosis viral oncogene homolog, c-Myc, MYCC, v-myc myelocytomatosis viral oncogene homolog, myc proto-oncogene protein, class E basic helix-loop-helix protein 39, transcription factor p64, bHLHe39, MRTL, cMyc, myc-related translation/localization regulatory factor, v-myc avian myelocytomatosis viral oncogene homolog
Source: HGNC:7553
Biotype: protein coding gene
A2M
(Homo sapiens)Gene
Name: alpha-2-macroglobulin
Synonyms: CPAMD5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, A2MD, alpha-2-M, FWP007, DKFZp779B086, S863-7
Source: HGNC:7
Biotype: protein coding gene
Ttr
(Mus musculus)Gene
Name: transthyretin
Synonyms: TT, expressed sequence AA408768, AA408768, prealbumin, expressed sequence AI787086, expressed sequence D17860, Tbpa, Lr1, AI787086, D17860
Source: MGI:98865
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
KRAS
(Homo sapiens)Gene
Name: KRAS proto-oncogene, GTPase
Synonyms: KI-RAS, RALD, NS, c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, PR310 c-K-ras oncogene, KRAS-ENOPH fusion, K-RAS2B, GTPase KRas, K-RAS2A, NS3, K-RAS4B, K-RAS4A, c-Kirsten-ras protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, Kirsten rat sarcoma viral proto-oncogene, c-Ki-ras, Kirsten rat sarcoma viral oncogene homolog, oncogene KRAS2, K-ras p21 protein, RASK2, CFC2, K-Ras, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, C-K-RAS, K-Ras 2, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, OES, cellular transforming proto-oncogene, KRAS2, 'C-K-RAS, proto-oncogene GTPase, transforming protein p21, KRAS1
Source: HGNC:6407
Biotype: protein coding gene
BCL2
(Homo sapiens)Gene
Name: BCL2 apoptosis regulator
Synonyms: Bcl-2, protein phosphatase 1, regulatory subunit 50, Bcl-2a, B-cell CLL/lymphoma 2, PPP1R50, Bcl-2ß, apoptosis regulator Bcl-2, b-cell leukemia/lymphoma 2, BCL2, apoptosis regulator
Source: HGNC:990
Biotype: protein coding gene
Braf
(Mus musculus)Gene
Name: Braf transforming gene
Synonyms: expressed sequence C87398, expressed sequence AA120551, expressed sequence AA387315, Braf-2, Braf2, AA387315, DNA segment, Chr 6, ERATO Doi 631, expressed, RIKEN cDNA 9930012E13 gene, C87398, AA120551, Braf transforming gene 2, D6Ertd631e, expressed sequence AA473386, AA473386, 9930012E13Rik
Source: MGI:88190
Biotype: protein coding gene
Tgfb1
(Mus musculus)Gene
Name: transforming growth factor, beta 1
Synonyms: Tgfb-1, TGF-beta 1, Tgfb, TGFbeta1, TGF-beta1
Source: MGI:98725
Biotype: protein coding gene
Stat3
(Mus musculus)Gene
Name: signal transducer and activator of transcription 3
Synonyms: RIKEN cDNA 1110034C02 gene, expressed sequence AW109958, 1110034C02Rik, Aprf, AW109958
Source: MGI:103038
Biotype: protein coding gene
Apc
(Mus musculus)Gene
Name: APC, WNT signaling pathway regulator
Synonyms: CC1, AI047805, expressed sequence AI047805, AU020952, adenomatosis polyposis coli, Min, expressed sequence AU020952, RATAPC, multiple intestinal neoplasia, expressed sequence AW124434, AW124434
Source: MGI:88039
Biotype: protein coding gene
Cdkn1a
(Mus musculus)Gene
Name: cyclin dependent kinase inhibitor 1A
Synonyms: CDKI, Cip1, p21Cip1, P21, Cdkn1, p21, cyclin dependent kinase inhibitor, CIP1, UV96, p21WAF, Waf1, CAP20, SDI1, mda6
Source: MGI:104556
Biotype: protein coding gene
daf-16
(Caenorhabditis elegans)Gene
Name: abnormal DAuer Formation 16
Synonyms: daf-17, R13H8.1, CELE_R13H8.1
Source: WB:WBGene00000912
Biotype: protein coding gene
Ptgs2
(Mus musculus)Gene
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX-2, Cox-2, PHS II, Cox2, Pghs2, cyclooxygenase-2, prostaglandin G/H synthase, PHS-2, COX2, PGHS-2, cyclooxygenase 2, Tis10
Source: MGI:97798
Biotype: protein coding gene
Mmp2
(Mus musculus)Gene
Name: matrix metallopeptidase 2
Synonyms: GelA, MMP-2, collagenase IVA, basement membrane, 72 kDa, gelatinase A, Clg4a, 72kDa type IV collagenase, 72kDa gelatinase
Source: MGI:97009
Biotype: protein coding gene
ERCC2
(Homo sapiens)Gene
Name: ERCC excision repair 2, TFIIH core complex helicase subunit
Synonyms: general transcription and DNA repair factor IIH helicase subunit XPD, TTD, TFIIH basal transcription factor complex 80 kDa subunit, TTD1, TFIIH basal transcription factor complex helicase subunit, COFS2, DNA 5'-3' helicase XPD, XPD, EM9, excision repair cross-complementing rodent repair deficiency, complementation group 2, xeroderma pigmentosum complementary group D, xeroderma pigmentosum group D-complementing protein, BTF2 p80, basic transcription factor 2 80 kDa subunit, trichothiodystrophy, MGC102762, MGC126218, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex helicase XPB subunit, MGC126219, excision repair cross-complementation group 2, TFIIH basal transcription factor complex helicase XPD subunit, TFIIH subunit XPD, TFIIH, CXPD, TFIIH p80, TFIIH 80 kDa subunit, DNA excision repair protein ERCC-2
Source: HGNC:3434
Biotype: protein coding gene
A2m
(Rattus norvegicus)Gene
Name: alpha-2-macroglobulin
Synonyms: A2maa, AI893533, alpha-2-M, A2mb, Mam, MGC114358, alpha-2-macroglobulin-like, RATA2MAC1, A2m1, A2MAC1, LOC100911545, alpha-2-macroglobulin-P
Source: RGD:2004
Biotype: protein coding gene
MMP2
(Homo sapiens)Gene
Name: matrix metallopeptidase 2
Synonyms: matrix metalloproteinase-2, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase), TBE-1, CLG4, matrix metalloproteinase 2 (gelatinase a, 72kda gelatinase, 72kda type iv collagenase), 72 kDa gelatinase, collagenase type IV-A, MONA, MMP-2, matrix metalloproteinase-II, CLG4A, gelatinase A, MMP-II, 72 kDa type IV collagenase, neutrophil gelatinase
Source: HGNC:7166
Biotype: protein coding gene
ttr
(Danio rerio)Gene
Name: transthyretin (prealbumin, amyloidosis type I)
Synonyms: zgc:103583
Source: ZFIN:ZDB-GENE-040927-14
Biotype: protein coding gene
CCC2
(Saccharomyces cerevisiae)Gene
Name: Cross-Complements Ca(2+) phenotype of csg1
Synonyms: YDR270W
Source: SGD:S000002678
Biotype: protein coding gene
CDKN1B
(Homo sapiens)Gene
Name: cyclin dependent kinase inhibitor 1B
Synonyms: CDKN4, cyclin-dependent kinase inhibitor 1B, MEN1B, MEN4, P27KIP1, KIP1, cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Source: HGNC:1785
Biotype: protein coding gene
Ezh2
(Mus musculus)Gene
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: enhancer of zeste homolog (Drosophila), Enx-1, Enx1h, KMT6
Source: MGI:107940
Biotype: protein coding gene
daf-18
(Caenorhabditis elegans)Gene
Name: abnormal DAuer Formation 18
Synonyms: T07A9.6, CELE_T07A9.6
Source: WB:WBGene00000913
Biotype: protein coding gene
Kras
(Mus musculus)Gene
Name: Kirsten rat sarcoma viral oncogene homolog
Synonyms: Kras-2, expressed sequence AI929937, K-ras, AI929937, c-Ki-ras, Ki-ras, Kirsten rat sarcoma oncogene 2, expressed, p21, Kras2
Source: MGI:96680
Biotype: protein coding gene
p53
(Drosophila melanogaster)Gene
Name: p53
Synonyms: CG33336, CG10873, dp53, DMP53, Dp53, P53, prac, dmp53, D-p53, Dmp53, Dm-P53, DmP53, dmP53, protein 53, CG31325, p53-like regulator of apoptosis and cell cycle, Drosophila p53
Source: FB:FBgn0039044
Biotype: protein coding gene
SMAD4
(Homo sapiens)Gene
Name: SMAD family member 4
Synonyms: hSMAD4, deleted in pancreatic carcinoma locus 4, MADH4, MAD homolog 4, mothers against decapentaplegic homolog 4, SMAD 4, mothers against DPP homolog 4, deletion target in pancreatic carcinoma 4, JIP, MAD, mothers against decapentaplegic homolog 4, mothers against decapentaplegic, Drosophila, homolog of, 4, smad, mothers against dpp homolog 4 (drosophila), MYHRS, DPC4, SMAD, mothers against DPP homolog 4
Source: HGNC:6770
Biotype: protein coding gene
Vhl
(Mus musculus)Gene
Name: von Hippel-Lindau tumor suppressor
Synonyms: von Hippel-Lindau syndrome homolog, Vhlh, pVHL
Source: MGI:103223
Biotype: protein coding gene
Tp53
(Rattus norvegicus)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor protein p53 (Li-Fraumeni syndrome), Trp53, tumor suppressor p53, transformation related protein 53, MGC112612, p53
Source: RGD:3889
Biotype: protein coding gene
Snca
(Mus musculus)Gene
Name: synuclein, alpha
Synonyms: alpha-Syn, alphaSYN, alpha-synuclein
Source: MGI:1277151
Biotype: protein coding gene
age-1
(Caenorhabditis elegans)Gene
Name: AGEing alteration 1
Synonyms: CELE_B0334.8, B0334.8, daf-23
Source: WB:WBGene00000090
Biotype: protein coding gene
Sdha
(Mus musculus)Gene
Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Synonyms: C81073, expressed sequence C81073, RIKEN cDNA 2310034D06 gene, 2310034D06Rik, SDHF, FP, SDH2
Source: MGI:1914195
Biotype: protein coding gene
FUS3
(Saccharomyces cerevisiae)Gene
Name: cell FUSion
Synonyms: DAC2, YBL016W
Source: SGD:S000000112
Biotype: protein coding gene
Raf1
(Mus musculus)Gene
Name: v-raf-leukemia viral oncogene 1
Synonyms: 6430402F14Rik, c-Raf, expressed sequence AA990557, Raf-1, Craf1 transforming gene, sarcoma 3611 oncogene, v-Raf, expressed sequence BB129353, AA990557, BB129353, Craf1, murine sarcoma 3611 oncogene 1, RIKEN cDNA 6430402F14 gene
Source: MGI:97847
Biotype: protein coding gene
let-60
(Caenorhabditis elegans)Gene
Name: LEThal 60
Synonyms: lin-34, ZK792.6, CELE_ZK792.6
Source: WB:WBGene00002335
Biotype: protein coding gene
Cav1
(Mus musculus)Gene
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1, Cav
Source: MGI:102709
Biotype: protein coding gene
Bdnf
(Mus musculus)Gene
Name: brain derived neurotrophic factor
Synonyms: Not Available
Source: MGI:88145
Biotype: protein coding gene
BMP4
(Homo sapiens)Gene
Name: bone morphogenetic protein 4
Synonyms: MCOPS6, bone morphogenetic protein 2B, bone morphogenetic protein 4 preproprotein, BMP2B, OFC11, BMP-2B, BMP-4, ZYME, BMP2B1
Source: HGNC:1071
Biotype: protein coding gene
Bax
(Mus musculus)Gene
Name: BCL2-associated X protein
Synonyms: Not Available
Source: MGI:99702
Biotype: protein coding gene
INS
(Homo sapiens)Gene
Name: insulin
Synonyms: IRDN, proinsulin, preproinsulin, insulin-dependent diabetes mellitus 2, PNDM4, IDDM, ILPR, insulin isoform U3B, MODY10, IDDM1, IDDM2
Source: HGNC:6081
Biotype: protein coding gene
Tsc1
(Mus musculus)Gene
Name: TSC complex subunit 1
Synonyms: tuberous sclerosis 1, hamartin
Source: MGI:1929183
Biotype: protein coding gene
Il6
(Mus musculus)Gene
Name: interleukin 6
Synonyms: ILg6, Ifnb2, Il-6
Source: MGI:96559
Biotype: protein coding gene
EZH2
(Homo sapiens)Gene
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: ENX1, ENX-1, enhancer of zeste 2, lysine N-methyltransferase 6, KMT6, histone-lysine N-methyltransferase EZH2, enhancer of zeste homolog 2, WVS, EZH2b, WVS2, MGC9169, KMT6A, EZH1
Source: HGNC:3527
Biotype: protein coding gene
Stat92E
(Drosophila melanogaster)Gene
Name: Signal-transducer and activator of transcription protein at 92E
Synonyms: dSTAT92E/marelle, l(3)j6C8, D-stat, mrL, stat[92E], signal transducers and activator of transcription, STAT92, DmSTAT, signal transducer and activator of transcription, SD-stat, DRODSRC, Dstat92E, dstat, STAT92E, dSTAT, CG4257, Stat9E, stat92E, Stat, pSTAT, D-STAT, d-STAT, Stat92e, Dstat 92E, Stat1alpha-like, D-stat/stat92E, stat92, DSRC, stat, Signal-transducer and activator of transcription protein, Dst, Marelle, mrl, STAT 92E, Dstat, STAT92e, pSTAT92E, STAT, stat92e, D-Stat, dSTAT92E, Stat92E, mrl stat92E, marelle, DSTAT, l(3)06346, Sta92E, Stat92
Source: FB:FBgn0016917
Biotype: protein coding gene
Hgf
(Mus musculus)Gene
Name: hepatocyte growth factor
Synonyms: NK2, HPTA, NK1, scatter factor, C230052L06Rik, RIKEN cDNA C230052L06 gene, SF/HGF, HGF/SF
Source: MGI:96079
Biotype: protein coding gene