Version: 8.0.0Date: Tue Jan 28 2025
Gene Molecular Function: RNA polymerase II-specific DNA-binding transcription factor binding
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
STAT5B
(Homo sapiens)Gene
Name: signal transducer and activator of transcription 5B
Synonyms: transcription factor STAT5B, STAT5, GHISID2
Source: HGNC:11367
Biotype: protein coding gene
SIRT1
(Homo sapiens)Gene
Name: sirtuin 1
Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, regulatory protein SIR2 homolog 1, hSIRT1, hSIR2, sirtuin type 1, NAD-dependent deacetylase sirtuin-1
Source: HGNC:14929
Biotype: protein coding gene
Actb
(Mus musculus)Gene
Name: actin, beta
Synonyms: A-X actin-like protein, E430023M04Rik, RIKEN cDNA E430023M04 gene, Actx, melanoma X-actin, beta-actin
Source: MGI:87904
Biotype: protein coding gene
ACTB
(Homo sapiens)Gene
Name: actin beta
Synonyms: actin, cytoplasmic 1, DDS1, beta cytoskeletal actin, actin, beta, CSMH, PS1TP5BP1, BNS, PS1TP5-binding protein 1, BKRNS, I(2)-actin, BRWS1, THC8
Source: HGNC:132
Biotype: protein coding gene
Stat3
(Mus musculus)Gene
Name: signal transducer and activator of transcription 3
Synonyms: RIKEN cDNA 1110034C02 gene, expressed sequence AW109958, 1110034C02Rik, Aprf, AW109958
Source: MGI:103038
Biotype: protein coding gene
Pou5f1
(Mus musculus)Gene
Name: POU domain, class 5, transcription factor 1
Synonyms: Oct-4, Oct-3, Otf-4, Otf-3, octamer binding transcription factor 4, octamer binding transcription factor 3, Oct3/4, Oct4, Otf4, Otf3, Oct-3/4, Otf3-rs7, Otf3g, octamer binding transcription factor 3 related sequence 7
Source: MGI:101893
Biotype: protein coding gene
TP53BP1
(Homo sapiens)Gene
Name: tumor protein p53 binding protein 1
Synonyms: p53-binding protein 1, FLJ41424, tumor protein p53-binding protein, 1, TDRD30, p53BP1, MGC138366, 53BP1, p202, tumor protein 53-binding protein, 1, TP53-binding protein 1, TP53, tumor suppressor p53-binding protein 1
Source: HGNC:11999
Biotype: protein coding gene
GAL4
(Saccharomyces cerevisiae)Gene
Name: GALactose metabolism
Synonyms: YPL248C, GAL81
Source: SGD:S000006169
Biotype: protein coding gene
MCM1
(Saccharomyces cerevisiae)Gene
Name: MiniChromosome Maintenance
Synonyms: FUN80, YMR043W
Source: SGD:S000004646
Biotype: protein coding gene
ESR1
(Homo sapiens)Gene
Name: estrogen receptor 1
Synonyms: estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha 3*,4,5,6,7*/822 isoform, estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform, oestrogen receptor alpha, estrogen receptor alpha splice variant, ERalphai67, nuclear receptor subfamily 3 group A member 1, NR3A1, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 3*,4,5,6,7*/819-2 isoform, ESTRR, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, ERalphaDup5, estradiol receptor, ESR, estrogen receptor, E2 receptor alpha, estrogen receptor alpha splice variant, ERalphai45bL, estrogen nuclear receptor alpha, estrogen receptor alpha splice variant, ERalphai56, ER, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bS, Era, estrogen receptor alpha delta 4*,5,6,7*/654 isoform, estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform, ESRA, ER-alpha, DKFZp686N23123
Source: HGNC:3467
Biotype: protein coding gene
ARID1A
(Homo sapiens)Gene
Name: AT-rich interaction domain 1A
Synonyms: chromatin remodeling factor p250, MRD14, hOSA1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1, C1orf4, brain protein 120, SMARCF1, BM029, AT-rich interactive domain-containing protein 1A, SWI/SNF complex protein p270, osa homolog 1, OSA1, BAF250, SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1, P270, OSA1 nuclear protein, BAF250a, hELD, BRG1-associated factor 250a, ARID domain-containing protein 1A, SWI-like protein, BRG1-associated factor 250, CSS2, AT rich interactive domain 1A (SWI-like), B120, ELD
Source: HGNC:11110
Biotype: protein coding gene
Foxp2
(Mus musculus)Gene
Name: forkhead box P2
Synonyms: 2810043D05Rik, RGD1559697, RIKEN cDNA 2810043D05 gene, expressed sequence AI449000, AI449000, D0Kist7, DNA segment, KIST 7
Source: MGI:2148705
Biotype: protein coding gene
PPARG
(Homo sapiens)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: peroxisome proliferator-activated receptor-gamma splicing, peroxisome proliferator activated receptor, gamma, GLM1, PPARgamma, NR1C3, PPAR gamma, PPAR-gamma, PPARG1, peroxisome proliferator-activated receptor gamma 1, PPARG2, peroxisome proliferator-activated receptor-gamma 5, CIMT1, PPARG5, peroxisome proliferator-activated nuclear receptor gamma variant 1, peroxisome proliferator-activated receptor gamma, nuclear receptor subfamily 1 group C member 3
Source: HGNC:9236
Biotype: protein coding gene
Ctnnb1
(Mus musculus)Gene
Name: catenin beta 1
Synonyms: beta-catenin, beta catenin, Catnb, batface, catenin beta, catenin (cadherin associated protein), beta 1, Bfc
Source: MGI:88276
Biotype: protein coding gene
Mef2c
(Mus musculus)Gene
Name: myocyte enhancer factor 2C
Synonyms: RIKEN cDNA 5430401D19 gene, RIKEN cDNA 9930028G15 gene, 5430401D19Rik, AV011172, expressed sequence AV011172, 9930028G15Rik, RGD1563119
Source: MGI:99458
Biotype: protein coding gene
Ahr
(Mus musculus)Gene
Name: aryl-hydrocarbon receptor
Synonyms: Ahh, dioxin receptor, bHLHe76, Ahre, In, Ah, aryl hydrocarbon hydroxylase, inflammatory reactivity, aromatic hydrocarbon responsiveness
Source: MGI:105043
Biotype: protein coding gene
Foxp3
(Mus musculus)Gene
Name: forkhead box P3
Synonyms: RGD1562112, sf, scurfy, scurfin, JM2
Source: MGI:1891436
Biotype: protein coding gene
Pparg
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: Nr1c3, PPARgamma2, Ppar-gamma2, PPARgamma, PPAR-gamma
Source: MGI:97747
Biotype: protein coding gene
HSPB1
(Homo sapiens)Gene
Name: heat shock protein family B (small) member 1
Synonyms: epididymis secretory protein Li 102, HEL-S-102, HMND3, heat shock protein beta-1, heat shock 27kD protein 1, HMN2B, Hsp25, putative heat shock protein family B member 1 isoform, heat shock 27kDa protein 1, CMT2F, estrogen-regulated 24 kDa protein, SRP27, stress-responsive protein 27, heat shock 27 kDa protein, HSP 27, heat shock protein family B member 1, HS.76067, HSP28, HSP27, DKFZp586P1322, 28 kDa heat shock protein
Source: HGNC:5246
Biotype: protein coding gene
Eomes
(Mus musculus)Gene
Name: eomesodermin
Synonyms: C77258, T-box brain gene 2, Tbr2, expressed sequence C77258
Source: MGI:1201683
Biotype: protein coding gene
p53
(Drosophila melanogaster)Gene
Name: p53
Synonyms: CG33336, CG10873, dp53, DMP53, Dp53, P53, prac, dmp53, D-p53, Dmp53, Dm-P53, DmP53, dmP53, protein 53, CG31325, p53-like regulator of apoptosis and cell cycle, Drosophila p53
Source: FB:FBgn0039044
Biotype: protein coding gene
JUN
(Homo sapiens)Gene
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Synonyms: v-jun sarcoma virus 17 oncogene homolog, jun oncogene, AP1, enhancer-binding protein AP1, proto-oncogene c-Jun, AP-1, transcription factor AP-1, transcription factor AP-1 subunit Jun, cJUN, Jun activation domain binding protein, c-Jun, transcription factor Jun, activator protein 1, v-jun avian sarcoma virus 17 oncogene homolog, p39, jun proto-oncogene, proto-oncogene cJun
Source: HGNC:6204
Biotype: protein coding gene
SMAD4
(Homo sapiens)Gene
Name: SMAD family member 4
Synonyms: hSMAD4, deleted in pancreatic carcinoma locus 4, MADH4, MAD homolog 4, mothers against decapentaplegic homolog 4, SMAD 4, mothers against DPP homolog 4, deletion target in pancreatic carcinoma 4, JIP, MAD, mothers against decapentaplegic homolog 4, mothers against decapentaplegic, Drosophila, homolog of, 4, smad, mothers against dpp homolog 4 (drosophila), MYHRS, DPC4, SMAD, mothers against DPP homolog 4
Source: HGNC:6770
Biotype: protein coding gene
Tp53
(Rattus norvegicus)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor protein p53 (Li-Fraumeni syndrome), Trp53, tumor suppressor p53, transformation related protein 53, MGC112612, p53
Source: RGD:3889
Biotype: protein coding gene
Sirt1
(Mus musculus)Gene
Name: sirtuin 1
Synonyms: Sir2, expressed sequence AA673258, AA673258, Sir2alpha
Source: MGI:2135607
Biotype: protein coding gene
GCN4
(Saccharomyces cerevisiae)Gene
Name: General Control Nonderepressible
Synonyms: YEL009C, AAS101, ARG9, AAS3
Source: SGD:S000000735
Biotype: protein coding gene
Gata3
(Mus musculus)Gene
Name: GATA binding protein 3
Synonyms: juvenile alopecia, jal, Gata-3
Source: MGI:95663
Biotype: protein coding gene
Ppargc1a
(Mus musculus)Gene
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Synonyms: Pgc1, Pgc-1alpha, PGCvf-1, ENSMUSG00000079510, A830037N07Rik, predicted gene, ENSMUSG00000079510, PGC-1v, Gm11133, PPAR Gamma Coactivator-1, LRPGC1, PGCvf, PPAR gamma coactivator 1, PGCvf1, Ppargc1, Pgco1, predicted gene 11133, RIKEN cDNA A830037N07 gene, Pgc-1alphaa
Source: MGI:1342774
Biotype: protein coding gene
FOS
(Homo sapiens)Gene
Name: Fos proto-oncogene, AP-1 transcription factor subunit
Synonyms: cellular oncogene fos, FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS), Fos proto-oncogene, AP-1 trancription factor subunit, C-FOS, AP-1, p55, G0/G1 switch regulatory protein 7, activator protein 1, cellular oncogene c-fos, v-fos FBJ murine osteosarcoma viral oncogene homolog, proto-oncogene c-Fos, transcription factor AP-1 subunit c-Fos, FBJ murine osteosarcoma viral oncogene homolog
Source: HGNC:3796
Biotype: protein coding gene
Tbx3
(Mus musculus)Gene
Name: T-box 3
Synonyms: DNA segment, Chr 5, ERATO Doi 189, expressed, D5Ertd189e
Source: MGI:98495
Biotype: protein coding gene
Sox2
(Mus musculus)Gene
Name: SRY (sex determining region Y)-box 2
Synonyms: RGD1565646, yellow submarine, Sox-2, ysb, light coat and circling, lcc
Source: MGI:98364
Biotype: protein coding gene
Foxp1
(Mus musculus)Gene
Name: forkhead box P1
Synonyms: 3110052D19Rik, 4932443N09Rik, RIKEN cDNA 3110052D19 gene, expressed sequence AW494214, AW494214, RIKEN cDNA 4932443N09 gene
Source: MGI:1914004
Biotype: protein coding gene
Gsk3b
(Mus musculus)Gene
Name: glycogen synthase kinase 3 beta
Synonyms: expressed sequence C86142, GSK-3beta, GSK3, RIKEN cDNA 8430431H08 gene, RIKEN cDNA 7330414F15 gene, GSK-3, 7330414F15Rik, C86142, 8430431H08Rik
Source: MGI:1861437
Biotype: protein coding gene
hif-1
(Caenorhabditis elegans)Gene
Name: HIF (Hypoxia Inducible Factor) homologa 1
Synonyms: CELE_F38A6.3, F38A6.3
Source: WB:WBGene00001851
Biotype: protein coding gene
Pitx2
(Mus musculus)Gene
Name: paired-like homeodomain transcription factor 2
Synonyms: RIKEN cDNA 9430085M16 gene, Pitx-2, solurshin, Pitx2b, Pitx2a, Brx1b, Otlx2, Pitx2c, Brx1a, Munc30, Brx1, Rieger syndrome protein, Ptx2, 9430085M16Rik, Rieg
Source: MGI:109340
Biotype: protein coding gene
Grm1
(Mus musculus)Gene
Name: glutamate receptor, metabotropic 1
Synonyms: wobbles, G protein coupled receptor, family C, group 1, member A, wobl, G protein-coupled receptor, family C, group 1, member A, rcw, RIKEN cDNA 4930455H15 gene, mGluR1, recoil wobbler, nmf373, Gprc1a, 4930455H15Rik, neuroscience mutagenesis facility, 373
Source: MGI:1351338
Biotype: protein coding gene
Gata4
(Mus musculus)Gene
Name: GATA binding protein 4
Synonyms: Gata-4
Source: MGI:95664
Biotype: protein coding gene
Lhx3
(Mus musculus)Gene
Name: LIM homeobox protein 3
Synonyms: Lim3, mLim-3, P-LIM
Source: MGI:102673
Biotype: protein coding gene
Rb1
(Mus musculus)Gene
Name: RB transcriptional corepressor 1
Synonyms: Rb, pRb, Rb-1, retinoblastoma 1
Source: MGI:97874
Biotype: protein coding gene
CDKN2A
(Homo sapiens)Gene
Name: cyclin dependent kinase inhibitor 2A
Synonyms: MTS1, cyclin-dependent kinase inhibitor 2A, isoform 4, cyclin-dependent kinase inhibitor 2A, CDK4 inhibitor p16-INK4, TP16, INK4, CDKN2A/ARF Intron 2 lncRNA, MLM, CDK4I, multiple tumor suppressor 1, MTS-1, INK4a, p16INK4a, multiple tumour suppressor 1, cyclin-dependent kinase 4 inhibitor A, cyclin-dependent kinase inhibitor p16, cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3, inhibitor of cdk4 A, p14ARF, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), CMM2, p16INK4, p19Arf, p16-INK4, P14, P16, ARF, CAI2, alternative reading frame, P19, cell cycle negative regulator beta, P16-INK4A, CDKN2
Source: HGNC:1787
Biotype: protein coding gene
Hand1
(Mus musculus)Gene
Name: heart and neural crest derivatives expressed 1
Synonyms: Thing1, eHAND, bHLHa27, eHand, Hxt, extraembryonic tissues, heart and neural crest derivatives expressed transcript 1, Ehand1, HLH transcription factor expressed in extraembryonic mesoderm and trophoblast, Th1
Source: MGI:103577
Biotype: protein coding gene
Rad23b
(Mus musculus)Gene
Name: RAD23 homolog B, nucleotide excision repair protein
Synonyms: AV001138, mHR23B, RIKEN cDNA 0610007D13 gene, 0610007D13Rik, expressed sequence AV001138
Source: MGI:105128
Biotype: protein coding gene
Tbx5
(Mus musculus)Gene
Name: T-box 5
Synonyms: Not Available
Source: MGI:102541
Biotype: protein coding gene
CTNNB1
(Homo sapiens)Gene
Name: catenin beta 1
Synonyms: beta-catenin, catenin (cadherin-associated protein), beta 1, MRD19, EVR7, catenin (cadherin-associated protein), beta 1, 88kDa, DKFZp686D02253, CTNNB, armadillo, FLJ37923, catenin beta-1, NEDSDV, FLJ25606
Source: HGNC:2514
Biotype: protein coding gene
Lef1
(Mus musculus)Gene
Name: lymphoid enhancer binding factor 1
Synonyms: expressed sequence AI451430, AI451430, lymphoid enhancer factor 1, Lef-1
Source: MGI:96770
Biotype: protein coding gene
Parp1
(Mus musculus)Gene
Name: poly (ADP-ribose) polymerase family, member 1
Synonyms: poly (ADP-ribose) polymerase, Adprt1, Parp-1, expressed sequence AI893648, Adprp, PARP, ARTD1, sPARP-1, Adprt, AI893648, RIKEN cDNA 5830444G22 gene, parp-1, 5830444G22Rik, C80510, expressed sequence C80510, ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1
Source: MGI:1340806
Biotype: protein coding gene
AR
(Homo sapiens)Gene
Name: androgen receptor
Synonyms: DHTR, HYSP1, dihydrotestosterone receptor, androgen receptor splice variant 4b, SBMA, AR8, spinal and bulbar muscular atrophy, AIS, androgen nuclear receptor variant 2, Kennedy disease, testicular feminization, NR3C4, SMAX1, KD, TFM, nuclear receptor subfamily 3 group C member 4, HUMARA
Source: HGNC:644
Biotype: protein coding gene
Ar
(Mus musculus)Gene
Name: androgen receptor
Synonyms: testicular feminization, AW320017, Andr, Tfm, expressed sequence AW320017
Source: MGI:88064
Biotype: protein coding gene