Version: 8.0.0Date: Tue Jan 28 2025
Gene Molecular Function: protein-containing complex binding
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Pten
(Mus musculus)Gene
Name: phosphatase and tensin homolog
Synonyms: B430203M17Rik, RIKEN cDNA B430203M17 gene, expressed sequence AI463227, RIKEN cDNA 2310035O07 gene, TEP1, Mmac, A130070J02Rik, MMAC1, AI463227, 2310035O07Rik, RIKEN cDNA A130070J02 gene
Source: MGI:109583
Biotype: protein coding gene
ATM
(Homo sapiens)Gene
Name: ATM serine/threonine kinase
Synonyms: serine/threonine kinase ATM, TEL1, telomere maintenance 1, homolog, MGC74674, human phosphatidylinositol 3-kinase homolog, ATDC, truncated ATM serine/threonine kinase, DKFZp781A0353, ATA, AT mutated, ATC, ataxia telangiectasia mutated, ATD, TEL1, ataxia telangiectasia mutated (includes complementation groups A, C and D), ATE, A-T mutated, serine-protein kinase ATM, TELO1, AT1
Source: HGNC:795
Biotype: protein coding gene
FLNA
(Homo sapiens)Gene
Name: filamin A
Synonyms: OPD, FLN-A, filamin-1, FLN1, FLN, XMVD, filamin A, alpha, XLVD, actin binding protein 280, FG syndrome 2, alpha filamin, MNS, filamin 1, DKFZp434P031, FMD, CSBS, FGS2, endothelial actin-binding protein, non-muscle filamin, OPD2, OPD1, NHBP, alpha-filamin, FLJ43642, filamin-A, ABPX, ABP-280, CVD1
Source: HGNC:3754
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
H2-K1
(Mus musculus)Gene
Name: histocompatibility 2, K1, K region
Synonyms: RT1-A2n, RT1-CE12, rt1-El, RT1-A, RT1-CE7, RT1-E2, RT1A-1, RT1A-2, RT1-C/E1, RT1-C/E5, RT1.A2(N), RT1-C/E3, RT1-C/E4, RT1.A1(N), RT1-A1n, RT1-C/E7, H-2K
Source: MGI:95904
Biotype: protein coding gene
BRAF
(Homo sapiens)Gene
Name: B-Raf proto-oncogene, serine/threonine kinase
Synonyms: serine/threonine-protein kinase B-raf, RAFB1, B-Raf serine/threonine-protein, B-RAF1, v-raf murine sarcoma viral oncogene homolog B1, v-raf murine sarcoma viral oncogene homolog B, p94, B-Raf proto-oncogene serine/threonine-protein kinase (p94), proto-oncogene B-Raf, MGC138284, MGC126806, NS7, B-raf, BRAF1, FLJ95109, 94 kDa B-raf protein, BRAF-1, murine sarcoma viral (v-raf) oncogene homolog B1
Source: HGNC:1097
Biotype: protein coding gene
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide(1-42), beta-amyloid peptide, preA4, beta-amyloid peptide(1-40), cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, alpha-sAPP, AD1, alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), protease nexin-II, CTFgamma, amyloid beta A4 protein, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
PTEN
(Homo sapiens)Gene
Name: phosphatase and tensin homolog
Synonyms: MHAM, DEC, PTENepsilon, 10q23del, phosphatase and tensin-like protein, PTEN1, mitochondrial PTENalpha, GLM2, PTEN variant PTEN-K267Rfs*9, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, CWS1, mutated in multiple advanced cancers 1, MMAC1, PTEN variant PTEN-L247*, PTEN variant PTEN-R234Afs*11, mitochondrial phosphatase and tensin protein alpha, TEP1, PTENgama, inositol polyphosphate 3-phosphatase, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, BZS, PTENbeta, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MGC11227
Source: HGNC:9588
Biotype: protein coding gene
EGFR
(Homo sapiens)Gene
Name: epidermal growth factor receptor
Synonyms: PIG61, NNCIS, receptor tyrosine-protein kinase erbB-1, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), erythroblastic leukemia viral (v-erb-b) oncogene homolog, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, NISBD2, HER1
Source: HGNC:3236
Biotype: protein coding gene
HLA-A
(Homo sapiens)Gene
Name: major histocompatibility complex, class I, A
Synonyms: HLA class I histocompatibility antigen, A-1 alpha chain, HLA A, HLAA, MHC class I antigen A*34, MHC class I antigen A*33, HLA class I histocompatibility antigen, A-43 alpha chain, MHC class I antigen A*32, MHC class I antigen A*31, HLA-A11, MHC class II antigen, HLA class I histocompatibility antigen, A-80 alpha chain, MHC class I antigen A*36, HLA class I histocompatibility antigen, A-23 alpha chain, HLA class I histocompatibility antigen, A-66 alpha chain, HLA class I histocompatibility antigen, A-9 alpha chain, aw-19, MHC class I antigen HLA-A33, truncated MHC class I antigen, MHC class I antigen A*30, MHC class I antigen A*74, MHC class I antigen A*1, leucocyte antigen A, HLA-Aw33.1, MHC class I antigen A*43, MHC class I anti, MHC class I antigen HLA-A heavy chain, HLA class I histocompatibility antigen, A-69 alpha chain-like, HLA class I histocompatibility antigen, A-26 alpha chain, HLA class I histocompatibility antigen, A-36 alpha chain, MHC class I antigen A*80, HLA class I histocompatibility antigen, A-28 alpha chain, aw-24, HLA class I histocompatibility antigen, A-24 alpha chain, HLA class I histocompatibility antigen, A-25 alpha chain, HLA class I histocompatibility antigen, A-29 alpha chain, aw-66, LOC100507703, leucocyte antigen class I, HLA-DQB1, MHC class I antigene, antigen presenting molecule, HLA class I antigen, FLJ26655, HLA class I histocompatibility antigen, A-31 alpha chain, MHC leukocyte antigen, HLA class I histocompatibility antigen, A-10 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, MHC class I antigen A*11, HLA-A33, HLA class I histocompatibility antigen, A-34 alpha chain, Aw-69, HLA-A locus alpha 2 domain, Aw-68, aw-34, leukocyte antigen class I-A, aw-36, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, A-30 alpha chain, MHC class I antigen heavy chain, MHC class I antigen A*29, aw-80, MHC class I antigen A*2, MCH class I antigen, MHC class I antigen A*3, MHC class I antigen A*23, HLA-A null, MHC class I antigen A*66, MHC class I antigen A*26, MHC class I antigen A*69, MHC class I antigen A*25, MHC class I antigen A*24, MHC class I antigen A*68, MHC classI antigen, HLA locus, HLA class I histocompatibility antigen, A alpha chain, MHC Class I antigen, MHC class 1 antigen, aw-43, Aw-33, Aw-74, HLA-DRB1
Source: HGNC:4931
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, MGC1571, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2
Source: HGNC:613
Biotype: protein coding gene
CFTR
(Homo sapiens)Gene
Name: CF transmembrane conductance regulator
Synonyms: CF, ABCC7, cystic fibrosis transmembrane conductance regulator, atp-binding cassette (sub-family c, member 7), MRP7, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7, dJ760C5.1, ATP-binding cassette sub-family C member 7, ABC35, cystic fibrosis transmembrane conductance regulator, TNR-CFTR, cystic fibrosis transmembrane conductance regulating, channel conductance-controlling ATPase, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Source: HGNC:1884
Biotype: protein coding gene
dpp
(Drosophila melanogaster)Gene
Name: decapentaplegic
Synonyms: shv, DPP, Dpp, ho, TGF-b, blink, M(2)23AB, DmDPP, l(2)10638, M(2)LS1, Decapentaplegic/Bone Morphogenetic Protein, Haplo-insufficient, TGF-beta, Tg, CG9885, DPP-C, TGFbeta, blk, Tegula, Hin-d, Bmp, BMP, Decapentaplegic, bone morphogenetic protein, l(2)22Fa, Tgfbeta, heldout, Dpp/TGFbeta, bone morphogenic protein, shortvein, l(2)k17036, Dm-DPP
Source: FB:FBgn0000490
Biotype: protein coding gene
MYC
(Homo sapiens)Gene
Name: MYC proto-oncogene, bHLH transcription factor
Synonyms: proto-oncogene c-Myc, avian myelocytomatosis viral oncogene homolog, c-Myc, MYCC, v-myc myelocytomatosis viral oncogene homolog, myc proto-oncogene protein, class E basic helix-loop-helix protein 39, transcription factor p64, bHLHe39, MRTL, cMyc, myc-related translation/localization regulatory factor, v-myc avian myelocytomatosis viral oncogene homolog
Source: HGNC:7553
Biotype: protein coding gene
Flna
(Mus musculus)Gene
Name: filamin, alpha
Synonyms: dilated pupils 2, filamin 1, filamin-1, Dilp2, actin-binding protein 280, Fln1, GENA 379, RIKEN cDNA F730004A14 gene, F730004A14Rik, ABP-280, RGD1560614
Source: MGI:95556
Biotype: protein coding gene
Ttr
(Mus musculus)Gene
Name: transthyretin
Synonyms: TT, expressed sequence AA408768, AA408768, prealbumin, expressed sequence AI787086, expressed sequence D17860, Tbpa, Lr1, AI787086, D17860
Source: MGI:98865
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
ERCC5
(Homo sapiens)Gene
Name: ERCC excision repair 5, endonuclease
Synonyms: xeroderma pigmentosum, complementation group G, ERCC5-201, UVDR, ERCM2, xeroderma pigmentosum group G-complementing protein, XPG, COFS3, excision repair protein, excision repair cross-complementing rodent repair deficiency, complementation group 5, DNA repair protein complementing XP-G cells, excision repair cross-complementation group 5, XPG-complementing protein, DNA excision repair protein ERCC-5, XPGC, xeroderma pigmentosum complementation group G protein
Source: HGNC:3437
Biotype: protein coding gene
KRAS
(Homo sapiens)Gene
Name: KRAS proto-oncogene, GTPase
Synonyms: KI-RAS, RALD, NS, c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, PR310 c-K-ras oncogene, KRAS-ENOPH fusion, K-RAS2B, GTPase KRas, K-RAS2A, NS3, K-RAS4B, K-RAS4A, c-Kirsten-ras protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, Kirsten rat sarcoma viral proto-oncogene, c-Ki-ras, Kirsten rat sarcoma viral oncogene homolog, oncogene KRAS2, K-ras p21 protein, RASK2, CFC2, K-Ras, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, C-K-RAS, K-Ras 2, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, OES, cellular transforming proto-oncogene, KRAS2, 'C-K-RAS, proto-oncogene GTPase, transforming protein p21, KRAS1
Source: HGNC:6407
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, Alzheimer disease amyloid beta protein, cerebrovascular amyloid peptide, protease nexin II, expressed sequence AL024401, AL024401, RIKEN cDNA E030013M08 gene, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
crb
(Drosophila melanogaster)Gene
Name: crumbs
Synonyms: Crbs, l(3)07207, CT19912, 0509/20, Crumbs, CG6383, 1384/04, Crb, CRB, crumb, crumbs, far, fat rhabdomere, l(3)S058104, DmCrb, l(3)S050920, lethal (3) 07207, l(3)j1B5, fat rhabdomeres
Source: FB:FBgn0259685
Biotype: protein coding gene
Dmd
(Mus musculus)Gene
Name: dystrophin, muscular dystrophy
Synonyms: mdx, X-linked muscular dystrophy, Duchenne muscular dystrophy, Dp71, DNADMD1, pke, pyruvate kinase expression, Dp427, dys
Source: MGI:94909
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: mechanistic target of rapamycin, rapamycin target protein 1, rapamycin and FKBP12 target 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FKBP12-rapamycin complex-associated protein 1, FRAP2, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, SKS, FRAP, serine/threonine-protein kinase mTOR, RAPT1, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
Braf
(Mus musculus)Gene
Name: Braf transforming gene
Synonyms: expressed sequence C87398, expressed sequence AA120551, expressed sequence AA387315, Braf-2, Braf2, AA387315, DNA segment, Chr 6, ERATO Doi 631, expressed, RIKEN cDNA 9930012E13 gene, C87398, AA120551, Braf transforming gene 2, D6Ertd631e, expressed sequence AA473386, AA473386, 9930012E13Rik
Source: MGI:88190
Biotype: protein coding gene
Tgfb1
(Mus musculus)Gene
Name: transforming growth factor, beta 1
Synonyms: Tgfb-1, TGF-beta 1, Tgfb, TGFbeta1, TGF-beta1
Source: MGI:98725
Biotype: protein coding gene
HLA-DRB1
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 1
Synonyms: MHC class II HLA-DRw10-beta, HLA-DRB1*, leucocyte antigen DRB1, DW2.2/DR2.2, FLJ76359, HLA-DR-beta 1, leucocyte antigen DR beta 1 chain, MHC class II antigen, major histocompatibility complex, class II, DR beta 1 precursor, DRw8, SS1, DR16, DR-8, MHC class II HLA-DR beta 1 chain, lymphocyte antigen DRB1, DRB1, DR-16, HLA class II histocompatibility antigen, DR-1 beta chain, DR1, MHC class II antigen HLA-DR13, DR5, FLJ75017, HLA class II antigen beta chain, DR8, DRw11, DRw10, MHC class II HLA-DR-beta cell surface glycoprotein, human leucocyte antigen DRB1, HLA-DR1B, HLA-DRB
Source: HGNC:4948
Biotype: protein coding gene
MTHFR
(Homo sapiens)Gene
Name: methylenetetrahydrofolate reductase
Synonyms: methylenetetrahydrofolate reductase (NAD(P)H), methylenetetrahydrofolate reductase (NADPH), 5,10-methylenetetrahydrofolate reductase (NADPH)
Source: HGNC:7436
Biotype: protein coding gene
BNI1
(Saccharomyces cerevisiae)Gene
Name: Bud Neck Involved
Synonyms: SHE5, YNL271C, PPF3
Source: SGD:S000005215
Biotype: protein coding gene
ACTB
(Homo sapiens)Gene
Name: actin beta
Synonyms: actin, cytoplasmic 1, DDS1, beta cytoskeletal actin, actin, beta, CSMH, PS1TP5BP1, BNS, PS1TP5-binding protein 1, BKRNS, I(2)-actin, BRWS1, THC8
Source: HGNC:132
Biotype: protein coding gene
myo-3
(Caenorhabditis elegans)Gene
Name: MYOsin heavy chain structural genes 3
Synonyms: CELE_K12F2.1, K12F2.1, sup-3
Source: WB:WBGene00003515
Biotype: protein coding gene
VCP
(Homo sapiens)Gene
Name: valosin containing protein
Synonyms: epididymis secretory protein Li 70, IBMPFD, valosin-containing protein, HEL-S-70, MGC148092, CMT2Y, TERA, FTDALS6, transitional endoplasmic reticulum ATPase, yeast Cdc48p homolog, p97, 15S Mg(2+)-ATPase p97 subunit, HEL-220, MGC8560, TER ATPase, CDC48, MGC131997, ALS14, IBMPFD1, epididymis luminal protein 220
Source: HGNC:12666
Biotype: protein coding gene
Apc
(Mus musculus)Gene
Name: APC, WNT signaling pathway regulator
Synonyms: CC1, AI047805, expressed sequence AI047805, AU020952, adenomatosis polyposis coli, Min, expressed sequence AU020952, RATAPC, multiple intestinal neoplasia, expressed sequence AW124434, AW124434
Source: MGI:88039
Biotype: protein coding gene
f
(Drosophila melanogaster)Gene
Name: forked
Synonyms: CG12996, CG5424, Forked, CG42864, X1
Source: FB:FBgn0262111
Biotype: protein coding gene
Cftr
(Mus musculus)Gene
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7, expressed sequence AW495489, AW495489, RGD1561193
Source: MGI:88388
Biotype: protein coding gene
TSSK2
(Homo sapiens)Gene
Name: testis specific serine kinase 2
Synonyms: TSK2, SPOGA2, serine/threonine kinase 22B (spermiogenesis associated), testis-specific serine/threonine-protein kinase 2, testis-specific kinase 2, testicular secretory protein Li 61, serine/threonine-protein kinase 22B, testis-specific serine kinase 2, spermiogenesis associated 2, TSSK-2, testis specific serine threonine kinase 2, FLJ38613, DGS-G, diGeorge syndrome protein G, TSK-2, STK22B
Source: HGNC:11401
Biotype: protein coding gene
H2-Aa
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen A, alpha
Synonyms: BA1, I-Aalpha, histocompatibility 2, class II antigen A alpha, H-2Aa, A alpha, Ia1, Aalpha, I region-associated antigen 1, Ia-1
Source: MGI:95895
Biotype: protein coding gene
Slc6a4
(Mus musculus)Gene
Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Synonyms: 5-HTT, 5-hydroxytryptamine (serotonin) transporter, SERT, Sert, Htt, AI323329, expressed sequence AI323329
Source: MGI:96285
Biotype: protein coding gene
Ezh2
(Mus musculus)Gene
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: enhancer of zeste homolog (Drosophila), Enx-1, Enx1h, KMT6
Source: MGI:107940
Biotype: protein coding gene
Cdkn1a
(Mus musculus)Gene
Name: cyclin dependent kinase inhibitor 1A
Synonyms: CDKI, Cip1, p21Cip1, P21, Cdkn1, p21, cyclin dependent kinase inhibitor, CIP1, UV96, p21WAF, Waf1, CAP20, SDI1, mda6
Source: MGI:104556
Biotype: protein coding gene
Cav1
(Mus musculus)Gene
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1, Cav
Source: MGI:102709
Biotype: protein coding gene
H2-Ab1
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen A, beta 1
Synonyms: Bb, expressed sequence AI845868, response to metastatic cancers 1, H-2Ab, RT1.B, H2-Ab, histocompatibility 2, class II antigen A, beta, IAb, Rmcs1, I-region-associated antigen 2, I-A, AI845868, A beta, Abeta, Ia2, I-Abeta, Ia-2
Source: MGI:103070
Biotype: protein coding gene
Prkn
(Mus musculus)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkinson disease (autosomal recessive, juvenile) 2, parkin, Park2, Parkin, Park
Source: MGI:1355296
Biotype: protein coding gene
Hba-a1
(Mus musculus)Gene
Name: hemoglobin alpha, adult chain 1
Synonyms: Glnc3, alpha 1 globin, Glnc2, GloA, HBAM, Hba1, Hba-a2, Hba2, Glnc1
Source: MGI:96015
Biotype: protein coding gene
Casp3
(Mus musculus)Gene
Name: caspase 3
Synonyms: RIKEN cDNA A830040C14 gene, Apopain, melody, CC3, A830040C14Rik, Yama, AC-3, CPP32, mldy, CPP32-beta, Lice, Caspase-3
Source: MGI:107739
Biotype: protein coding gene
Ctnnb1
(Mus musculus)Gene
Name: catenin beta 1
Synonyms: beta-catenin, beta catenin, Catnb, batface, catenin beta, catenin (cadherin associated protein), beta 1, Bfc
Source: MGI:88276
Biotype: protein coding gene
Ahr
(Mus musculus)Gene
Name: aryl-hydrocarbon receptor
Synonyms: Ahh, dioxin receptor, bHLHe76, Ahre, In, Ah, aryl hydrocarbon hydroxylase, inflammatory reactivity, aromatic hydrocarbon responsiveness
Source: MGI:105043
Biotype: protein coding gene
H2-Eb1
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen E beta
Synonyms: H-2Eb, Db1, I region-associated antigen 4, RT1-Db, RT1-Db1n, Ia-4, Ia4
Source: MGI:95901
Biotype: protein coding gene
Sparcl1
(Mus musculus)Gene
Name: SPARC-like 1
Synonyms: Sc1, Ecm2, hevin, mast9
Source: MGI:108110
Biotype: protein coding gene