Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: cell population proliferation
Sox9
(Rattus norvegicus)Gene
Name: SRY-box transcription factor 9
Synonyms: SRY-box containing gene 9, LOC363699, SRY (sex determining region Y)-box 9, SRY box 9, transcription factor SOX-9, LOC100361122, SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal), SRY
Source: RGD:620474
Biotype: protein coding gene
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Pten
(Mus musculus)Gene
Name: phosphatase and tensin homolog
Synonyms: B430203M17Rik, RIKEN cDNA B430203M17 gene, expressed sequence AI463227, RIKEN cDNA 2310035O07 gene, TEP1, Mmac, A130070J02Rik, MMAC1, AI463227, 2310035O07Rik, RIKEN cDNA A130070J02 gene
Source: MGI:109583
Biotype: protein coding gene
Msx1
(Mus musculus)Gene
Name: msh homeobox 1
Synonyms: Hox-7, msh, AA675338, expressed sequence AI324650, homeo box-7 cluster, msh-like, Hox7, AI324650, expressed sequence AA675338, muscle-segment homeobox, Hox7.1
Source: MGI:97168
Biotype: protein coding gene
Pax6
(Mus musculus)Gene
Name: paired box 6
Synonyms: 1500038E17Rik, AEY11, RIKEN cDNA 1500038E17 gene, Pax-6, Sey, gsf abnormal eyes 11, Dey, Dickie's small eye, Gsfaey11, small eye
Source: MGI:97490
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
STAT5B
(Homo sapiens)Gene
Name: signal transducer and activator of transcription 5B
Synonyms: transcription factor STAT5B, STAT5, GHISID2
Source: HGNC:11367
Biotype: protein coding gene
wg
(Drosophila melanogaster)Gene
Name: wingless
Synonyms: fg, flag, Wingless, I, wingless, Dint-1, l(2)rO727, D.int-1, WG, lethal (2) SH1281, l(2)SH1281, l(2)wg, Dwnt-1, dWnt, Glazed, Sternopleural, Wnt, WNT, wgl, Wnt1, glazed, wnt1, spd, Complementation group I, int-1, spade, Dm-1, Wg, Br, Dm Wg, DWint-1, Bristled, DWnt-1, l(2)SH2 1281, l(2)02657, wnt, Wnt-1, CG4889, Sp, Gla
Source: FB:FBgn0284084
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Bmp4
(Mus musculus)Gene
Name: bone morphogenetic protein 4
Synonyms: Bmp2b, bone morphogenetic protein 2b, BOMPR4A, Bmp2b-1, Bmp-4, bone morphogenetic protein 2b 1, Bmp2b1
Source: MGI:88180
Biotype: protein coding gene
BRCA2
(Homo sapiens)Gene
Name: BRCA2 DNA repair associated
Synonyms: truncated breast and ovarian cancer susceptibility protein 2, DNA repair-associated BRCA2, FAD1, truncated DNA repair-associated BRCA2, BRCC2, GLM3, BRCA2, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 2, breast cancer type 2 susceptibility protein, breast cancer 2, early onset, breast cancer 2 tumor suppressor, breast and ovarian cancer susceptibility gene, early onset, PNCA2, truncated BRCA2 DNA repair associated, fanconi anemia group D1 protein, truncated breast cancer 2, FAD, mutant BRCA2, breast cancer susceptibility protein BRCA2, FANCB, FANCD, breast and ovarian cancer susceptibility protein 2, mutant DNA repair-associated protein 2, FANCD1, BROVCA2, XRCC11, breast cancer 2, FACD
Source: HGNC:1101
Biotype: protein coding gene
PTEN
(Homo sapiens)Gene
Name: phosphatase and tensin homolog
Synonyms: MHAM, DEC, PTENepsilon, 10q23del, phosphatase and tensin-like protein, PTEN1, mitochondrial PTENalpha, GLM2, PTEN variant PTEN-K267Rfs*9, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, CWS1, mutated in multiple advanced cancers 1, MMAC1, PTEN variant PTEN-L247*, PTEN variant PTEN-R234Afs*11, mitochondrial phosphatase and tensin protein alpha, TEP1, PTENgama, inositol polyphosphate 3-phosphatase, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, BZS, PTENbeta, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, MGC11227
Source: HGNC:9588
Biotype: protein coding gene
EGFR
(Homo sapiens)Gene
Name: epidermal growth factor receptor
Synonyms: PIG61, NNCIS, receptor tyrosine-protein kinase erbB-1, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), erythroblastic leukemia viral (v-erb-b) oncogene homolog, ERBB1, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, NISBD2, HER1
Source: HGNC:3236
Biotype: protein coding gene
PAX6
(Homo sapiens)Gene
Name: paired box 6
Synonyms: paired box 6 PAX6A-ASdel6-AS7 isoform, paired box homeotic gene-6, AN1, AN2, paired box 6 PAX6B-ASdel6 isoform, AN, paired box 6 PAX6A-del6 isoform, D11S812E, paired box protein Pax-6, MGDA, Aniridia 1, Aniridia 2, FVH1, paired box 6 PAX6-12a isoform, aniridia type II protein, oculorhombin, MGC17209, paired box 6 PAX6D isoform, ASGD5, WAGR, paired box 6 PAX6A-ASdel6 isoform, alternative protein PAX6
Source: HGNC:8620
Biotype: protein coding gene
TYR
(Homo sapiens)Gene
Name: tyrosinase
Synonyms: SHEP3, OCA1, tumor rejection antigen AB, LB24-AB, SK29-AB, OCA1A, oculocutaneous albinism IA, CMM8, ATN, OCAIA, monophenol monooxygenase
Source: HGNC:12442
Biotype: protein coding gene
Kit
(Mus musculus)Gene
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: Dominant white spotting, gsf spotted coat 1, Fdc, c-KIT, Gsfsco1, dominant spotting, Ssm, gsf spotted coat 5, SCO5, Bs, SCO1, Tr-kit, W, CD117, spotted sterile male, Steel Factor Receptor, Gsfsow3, Gsfsco5, phenotype like Sl or W 3, belly-spot, SOW3
Source: MGI:96677
Biotype: protein coding gene
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
MYC
(Homo sapiens)Gene
Name: MYC proto-oncogene, bHLH transcription factor
Synonyms: proto-oncogene c-Myc, avian myelocytomatosis viral oncogene homolog, c-Myc, MYCC, v-myc myelocytomatosis viral oncogene homolog, myc proto-oncogene protein, class E basic helix-loop-helix protein 39, transcription factor p64, bHLHe39, MRTL, cMyc, myc-related translation/localization regulatory factor, v-myc avian myelocytomatosis viral oncogene homolog
Source: HGNC:7553
Biotype: protein coding gene
Mir223
(Mus musculus)Gene
Name: microRNA 223
Synonyms: miR-223, mmu-mir-223, Mirn223
Source: MGI:2684360
Biotype: miRNA gene
KRAS
(Homo sapiens)Gene
Name: KRAS proto-oncogene, GTPase
Synonyms: KI-RAS, RALD, NS, c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, PR310 c-K-ras oncogene, KRAS-ENOPH fusion, K-RAS2B, GTPase KRas, K-RAS2A, NS3, K-RAS4B, K-RAS4A, c-Kirsten-ras protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, Kirsten rat sarcoma viral proto-oncogene, c-Ki-ras, Kirsten rat sarcoma viral oncogene homolog, oncogene KRAS2, K-ras p21 protein, RASK2, CFC2, K-Ras, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, C-K-RAS, K-Ras 2, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, OES, cellular transforming proto-oncogene, KRAS2, 'C-K-RAS, proto-oncogene GTPase, transforming protein p21, KRAS1
Source: HGNC:6407
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
BCL2
(Homo sapiens)Gene
Name: BCL2 apoptosis regulator
Synonyms: Bcl-2, protein phosphatase 1, regulatory subunit 50, Bcl-2a, B-cell CLL/lymphoma 2, PPP1R50, Bcl-2ß, apoptosis regulator Bcl-2, b-cell leukemia/lymphoma 2, BCL2, apoptosis regulator
Source: HGNC:990
Biotype: protein coding gene
FGFR3
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 3
Synonyms: tyrosine kinase JTK4, JTK4, HSFGFR3EX, ACH, CEK2, fibroblast growth factor receptor 3 variant 4, achondroplasia, thanatophoric dwarfism, CD333, fibroblast growth factor receptor 3-S, hydroxyaryl-protein kinase, FGFR-3
Source: HGNC:3690
Biotype: protein coding gene
Tlr4
(Mus musculus)Gene
Name: toll-like receptor 4
Synonyms: lipopolysaccharide response, RAS-like, family 2, locus 8, Rasl2-8, Lps
Source: MGI:96824
Biotype: protein coding gene
Tgfb1
(Mus musculus)Gene
Name: transforming growth factor, beta 1
Synonyms: Tgfb-1, TGF-beta 1, Tgfb, TGFbeta1, TGF-beta1
Source: MGI:98725
Biotype: protein coding gene
HRAS
(Homo sapiens)Gene
Name: HRas proto-oncogene, GTPase
Synonyms: HAMSV, Ras family small GTP binding protein H-Ras, H-RASIDX, GTPase KRas, RASH1, Harvey rat sarcoma viral oncoprotein, ha-Ras, transformation gene: oncogene HAMSV, GTP- and GDP-binding peptide B, c-Ki-ras, p19 H-RasIDX protein, H-Ras-1, Ha-Ras1 proto-oncoprotein, p21ras, C-H-RAS, N-RAS, c-has/bas p21 protein, HRAS1, RASK2, Harvey rat sarcoma viral oncogene homolog, GTPase HRas, CTLO, Ki-Ras, c-K-ras, K-RAS, c-ras-Ki-2 activated oncogene, C-BAS/HAS, K-Ras 2, KRAS, C-HA-RAS1, v-Ha-ras Harvey rat sarcoma viral oncogene homolog, KRAS2, transforming protein p21
Source: HGNC:5173
Biotype: protein coding gene
Apc
(Mus musculus)Gene
Name: APC, WNT signaling pathway regulator
Synonyms: CC1, AI047805, expressed sequence AI047805, AU020952, adenomatosis polyposis coli, Min, expressed sequence AU020952, RATAPC, multiple intestinal neoplasia, expressed sequence AW124434, AW124434
Source: MGI:88039
Biotype: protein coding gene
IL10
(Homo sapiens)Gene
Name: interleukin 10
Synonyms: CSIF, MGC126450, MGC126451, TGIF, GVHDS, IL10A, T-cell growth inhibitory factor, cytokine synthesis inhibitory factor, interleukin-10, IL-10
Source: HGNC:5962
Biotype: protein coding gene
Ifng
(Mus musculus)Gene
Name: interferon gamma
Synonyms: If2f, IFN-gamma, IFNG2, Ifg
Source: MGI:107656
Biotype: protein coding gene
ABCB1
(Homo sapiens)Gene
Name: ATP binding cassette subfamily B member 1
Synonyms: P-GP, ATP-binding cassette, sub-family B (MDR/TAP), member 1, CLCS, ATP-binding cassette sub-family B member 1, ENPAT, PGY1, multidrug resistance protein 1, ATP-binding cassette, subfamily B, member 1, GP170, colchicin sensitivity, ATP-dependent translocase ABCB1, p-170, MDR1, ABC20, MGC163296, P-glycoprotein 1, P glycoprotein, phospholipid transporter ABCB1, doxorubicin resistance, CD243
Source: HGNC:40
Biotype: protein coding gene
shha
(Danio rerio)Gene
Name: sonic hedgehog signaling molecule a
Synonyms: shh, vertebrate hedgehog homolog, sonic you, sonic-you, vhh1, fc83d08, syu, wu:fc83d08
Source: ZFIN:ZDB-GENE-980526-166
Biotype: protein coding gene
N
(Drosophila melanogaster)Gene
Name: Notch
Synonyms: 16-178, 16-55, RICN, Abruptex, Chp, Co, EG:163A10.2, Confluens, split, anon-EST:Liang-1.12, Ax, dNotch, Nicd, Chopped, Notch, NOTCH, strawberry, clone 1.12, co, spl, shd, 1.1, nd, l(1)3Cb, NICD, CG3936, notchoid, n[fah], notch, fa, NECD, CT13012, EG:140G11.1, facet, l(1)Ax, l(1)N, swb
Source: FB:FBgn0004647
Biotype: protein coding gene
Brca2
(Mus musculus)Gene
Name: breast cancer 2, early onset
Synonyms: expressed sequence AW045498, AW045498, Fancd1, expressed sequence AI256696, AI256696, RAB163
Source: MGI:109337
Biotype: protein coding gene
Rag2
(Mus musculus)Gene
Name: recombination activating gene 2
Synonyms: Rag-2
Source: MGI:97849
Biotype: protein coding gene
Mef2c
(Mus musculus)Gene
Name: myocyte enhancer factor 2C
Synonyms: RIKEN cDNA 5430401D19 gene, RIKEN cDNA 9930028G15 gene, 5430401D19Rik, AV011172, expressed sequence AV011172, 9930028G15Rik, RGD1563119
Source: MGI:99458
Biotype: protein coding gene
Foxp3
(Mus musculus)Gene
Name: forkhead box P3
Synonyms: RGD1562112, sf, scurfy, scurfin, JM2
Source: MGI:1891436
Biotype: protein coding gene
H19
(Mus musculus)Gene
Name: H19, imprinted maternally expressed transcript
Synonyms: AI747191, expressed sequence AI747191
Source: MGI:95891
Biotype: lncRNA gene
Wnt3a
(Mus musculus)Gene
Name: wingless-type MMTV integration site family, member 3A
Synonyms: vestigial tail, Wnt-3a, vt
Source: MGI:98956
Biotype: protein coding gene
Cd24a
(Mus musculus)Gene
Name: CD24a antigen
Synonyms: nectadrin, heat stable antigen, lymphocyte antigen 52, HSA, cluster of differentiation 24, Ly-52
Source: MGI:88323
Biotype: protein coding gene
Kras
(Mus musculus)Gene
Name: Kirsten rat sarcoma viral oncogene homolog
Synonyms: Kras-2, expressed sequence AI929937, K-ras, AI929937, c-Ki-ras, Ki-ras, Kirsten rat sarcoma oncogene 2, expressed, p21, Kras2
Source: MGI:96680
Biotype: protein coding gene
Stat3
(Mus musculus)Gene
Name: signal transducer and activator of transcription 3
Synonyms: RIKEN cDNA 1110034C02 gene, expressed sequence AW109958, 1110034C02Rik, Aprf, AW109958
Source: MGI:103038
Biotype: protein coding gene
Cdkn1a
(Mus musculus)Gene
Name: cyclin dependent kinase inhibitor 1A
Synonyms: CDKI, Cip1, p21Cip1, P21, Cdkn1, p21, cyclin dependent kinase inhibitor, CIP1, UV96, p21WAF, Waf1, CAP20, SDI1, mda6
Source: MGI:104556
Biotype: protein coding gene
Hprt1
(Mus musculus)Gene
Name: hypoxanthine phosphoribosyltransferase 1
Synonyms: Hgprtase, expressed sequence C81579, hypoxanthine guanine phosphoribosyl transferase, Hprt, C81579, hypoxanthine guanine phosphoribosyl transferase 1
Source: MGI:96217
Biotype: protein coding gene
Cav1
(Mus musculus)Gene
Name: caveolin 1, caveolae protein
Synonyms: Cav-1, caveolin-1, Cav
Source: MGI:102709
Biotype: protein coding gene
Tyr
(Mus musculus)Gene
Name: tyrosinase
Synonyms: skin/coat color 35, Oca1, c, albino, skc35
Source: MGI:98880
Biotype: protein coding gene
Fgf8
(Mus musculus)Gene
Name: fibroblast growth factor 8
Synonyms: androgen induced growth factor, Fgf6c, Aigf, Fgf-8
Source: MGI:99604
Biotype: protein coding gene
MRE11
(Homo sapiens)Gene
Name: MRE11 homolog, double strand break repair nuclease
Synonyms: HNGS1, double-strand break repair protein MRE11A, MRE11 homolog A, DNA recombination and repair protein, MRE11A, MRE11B, endo/exonuclease Mre11, meiotic recombination 11 homolog A, double-strand break repair protein MRE11, MRE11 meiotic recombination 11-like protein A, MRE11 homolog A, double strand break repair nuclease, MRE11 meiotic recombination 11 homolog A, ATLD, AT-like disease, MRE11 homolog 1, MRE11 double strand break repair nuclease A, MRE11 homolog, double strand break repair nuclease A, meiotic recombination 11 homolog 1
Source: HGNC:7230
Biotype: protein coding gene
Foxp2
(Mus musculus)Gene
Name: forkhead box P2
Synonyms: 2810043D05Rik, RGD1559697, RIKEN cDNA 2810043D05 gene, expressed sequence AI449000, AI449000, D0Kist7, DNA segment, KIST 7
Source: MGI:2148705
Biotype: protein coding gene
Fgfr3
(Mus musculus)Gene
Name: fibroblast growth factor receptor 3
Synonyms: sam3, HBGFR, Fgfr-3
Source: MGI:95524
Biotype: protein coding gene
ACE
(Homo sapiens)Gene
Name: angiotensin I converting enzyme
Synonyms: CD143, dipeptidyl carboxypeptidase I, CD143 antigen, angiotensin 1 converting enzyme 1, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, testicular ECA, MGC26566, MVCD3, kininase II, peptidase P, ICH, DCP, ACE1, carboxycathepsin, dipeptidyl carboxypeptidase 1, angiotensin converting enzyme, somatic isoform, angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript, DCP1, angiotensin-converting enzyme
Source: HGNC:2707
Biotype: protein coding gene