Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: regulation of amide metabolic process
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, MGC1571, Alzheimer disease 2 (APOE*E4-associated, late onset), AD2
Source: HGNC:613
Biotype: protein coding gene
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: mechanistic target of rapamycin, rapamycin target protein 1, rapamycin and FKBP12 target 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FKBP12-rapamycin complex-associated protein 1, FRAP2, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, SKS, FRAP, serine/threonine-protein kinase mTOR, RAPT1, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
Ifng
(Mus musculus)Gene
Name: interferon gamma
Synonyms: If2f, IFN-gamma, IFNG2, Ifg
Source: MGI:107656
Biotype: protein coding gene
Casp3
(Mus musculus)Gene
Name: caspase 3
Synonyms: RIKEN cDNA A830040C14 gene, Apopain, melody, CC3, A830040C14Rik, Yama, AC-3, CPP32, mldy, CPP32-beta, Lice, Caspase-3
Source: MGI:107739
Biotype: protein coding gene
PLA2G6
(Homo sapiens)Gene
Name: phospholipase A2 group VI
Synonyms: intracellular membrane-associated calcium-independent phospholipase A2 beta, INAD1, palmitoyl-CoA hydrolase, NBIA2B, iPLA2beta, NBIA2A, calcium-independent phospholipase A2, IPLA2-VIA, group VI phospholipase A2, NBIA2, phospholipase A2, group VI (cytosolic, calcium-independent), CaI-PLA2, 85 kDa calcium-independent phospholipase A2, iPLA2, patatin-like phospholipase domain-containing protein 9, patatin-like phospholipase domain containing 9, PNPLA9, 2-lysophosphatidylcholine acylhydrolase, PLA2, iPLA2-beta, 85/88 kDa calcium-independent phospholipase A2, phospholipase a2, group vi, PARK14, GVI PLA2, cytosolic, calcium-independent phospholipase A2, GVI, neurodegeneration with brain iron accumulation 2
Source: HGNC:9039
Biotype: protein coding gene
Tp53
(Rattus norvegicus)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor protein p53 (Li-Fraumeni syndrome), Trp53, tumor suppressor p53, transformation related protein 53, MGC112612, p53
Source: RGD:3889
Biotype: protein coding gene
Snca
(Mus musculus)Gene
Name: synuclein, alpha
Synonyms: alpha-Syn, alphaSYN, alpha-synuclein
Source: MGI:1277151
Biotype: protein coding gene
NFE2L2
(Homo sapiens)Gene
Name: NFE2 like bZIP transcription factor 2
Synonyms: HEBP1, NRF2, nuclear factor (erythroid-derived 2)-like 2, nuclear factor, erythroid derived 2, like 2, Nrf-2, nuclear factor, erythroid 2 like 2, NF-E2-related factor 2, IMDDHH, nuclear factor, erythroid 2-like 2, nuclear factor erythroid 2-related factor 2, NFE2-related factor 2, nuclear factor erythroid-derived 2-like 2
Source: HGNC:7782
Biotype: protein coding gene
Pdk4
(Mus musculus)Gene
Name: pyruvate dehydrogenase kinase, isoenzyme 4
Synonyms: expressed sequence AV005916, AV005916
Source: MGI:1351481
Biotype: protein coding gene
Epha4
(Mus musculus)Gene
Name: Eph receptor A4
Synonyms: AI385584, RGD1560587, Hek8, 2900005C20Rik, rb, Cek8, expressed sequence AI385584, RIKEN cDNA 2900005C20 gene, segmentation receptor tyrosine kinase, Tyro1, rabbit, Sek, Sek1
Source: MGI:98277
Biotype: protein coding gene
Mtor
(Mus musculus)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: expressed sequence AI327068, AI327068, flat-top, RAFT1, 2610315D21Rik, flat, FKBP-rapamycin-associated protein FRAP, Frap1, mechanistic target of rapamycin (serine/threonine kinase), RAPT1, FK506 binding protein 12-rapamycin associated protein 1, RIKEN cDNA 2610315D21 gene
Source: MGI:1928394
Biotype: protein coding gene
Tnf
(Rattus norvegicus)Gene
Name: tumor necrosis factor
Synonyms: tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrosis factor (TNF superfamily, member 2), MGC124630, RATTNF, tumor necrosis factor-alpha, Tnfa, tumor necrosis factor-like, tumor necrosis factor alpha, tumor necrosis factor superfamily member 2, tumor necrosis factor superfamily, member 2, LOC103694380, cachectin
Source: RGD:3876
Biotype: protein coding gene
NTRK2
(Homo sapiens)Gene
Name: neurotrophic receptor tyrosine kinase 2
Synonyms: tropomyosin-related kinase B, trkB tyrosine kinase, neurotrophic tyrosine kinase receptor type 2, EIEE58, GP145-TrkB, neurotrophic tyrosine kinase, receptor, type 2, OBHD, TRKB, BDNF-tropomyosine receptor kinase B, neurotrophic tyrosine receptor kinase type 2, DEE58, trk-B, tyrosine kinase receptor B, BDNF/NT-3 growth factors receptor
Source: HGNC:8032
Biotype: protein coding gene
PRKAA1
(Homo sapiens)Gene
Name: protein kinase AMP-activated catalytic subunit alpha 1
Synonyms: MGC57364, ACACA kinase, AMPK subunit alpha-1, acetyl-CoA carboxylase kinase, hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, tau-protein kinase PRKAA1, AMP-activated protein kinase, catalytic, alpha-1, AMPK, alpha, 1, 5'-AMP-activated protein kinase, catalytic alpha-1 chain, AMPK, AMPKa1, AMPK alpha 1, 5'-AMP-activated protein kinase catalytic subunit alpha-1, MGC33776, AMP -activate kinase alpha 1 subunit
Source: HGNC:9376
Biotype: protein coding gene
IGF1
(Homo sapiens)Gene
Name: insulin like growth factor 1
Synonyms: IGF-I, IGFI, insulin-like growth factor I, IGF-IB, IGF-IA, insulin-like growth factor 1 (somatomedin C), IGF, mechano growth factor, MGF, somatomedin-C, insulin-like growth factor IA, insulin-like growth factor IB, insulin-like growth factor 1, IGF1A
Source: HGNC:5464
Biotype: protein coding gene
CHRNA7
(Homo sapiens)Gene
Name: cholinergic receptor nicotinic alpha 7 subunit
Synonyms: neuronal acetylcholine receptor protein, alpha-7 chain, NACHRA7, a7 nicotinic acetylcholine receptor, acetylcholine receptor, nicotinic, alpha 7 (neuronal), neuronal acetylcholine receptor subunit alpha-7, CHRNA7-2, cholinergic receptor, nicotinic, alpha polypeptide 7, cholinergic receptor, nicotinic alpha 7, cholinergic receptor, nicotinic, alpha 7 (neuronal), alpha-7 nicotinic cholinergic receptor subunit, alpha 7 neuronal nicotinic acetylcholine receptor
Source: HGNC:1960
Biotype: protein coding gene
Eed
(Mus musculus)Gene
Name: embryonic ectoderm development
Synonyms: ENSMUSG00000039373, l7Rn5, lethal, Chr 7, Rinchik 5, predicted gene, ENSMUSG00000039373, l(7)5Rn
Source: MGI:95286
Biotype: protein coding gene
Rock1
(Mus musculus)Gene
Name: Rho-associated coiled-coil containing protein kinase 1
Synonyms: P160Rock, RIKEN cDNA 1110055K06 gene, 1110055K06Rik, ROCK-I, Rock-I
Source: MGI:107927
Biotype: protein coding gene
EIF2AK3
(Homo sapiens)Gene
Name: eukaryotic translation initiation factor 2 alpha kinase 3
Synonyms: PRKR-like endoplasmic reticulum kinase, hsPEK, eukaryotic translation initiation factor 2-alpha kinase 3, heme-regulated EIF2-alpha kinase, PKR-like ER kinase, PERK, truncated eukaryotic translation initiation factor 2 alpha kinase 3, DKFZp781H1925, PEK, WRS, HRI, pancreatic EIF2-alpha kinase, pancreatic eIF-2alpha kinase
Source: HGNC:3255
Biotype: protein coding gene
CLU
(Homo sapiens)Gene
Name: clusterin
Synonyms: TRPM-2, CLI, APO-J, apolipoprotein J, complement lysis inhibitor, SGP2, aging-associated protein 4, TRPM2, SGP-2, AAG4, MGC24903, APOJ, NA1/NA2, testosterone-repressed prostate message 2, complement-associated protein SP-40,40, sulfated glycoprotein 2, CLU2, SP-40, CLU1, KUB1, complement cytolysis inhibitor, ku70-binding protein 1
Source: HGNC:2095
Biotype: protein coding gene
Nfe2l2
(Mus musculus)Gene
Name: nuclear factor, erythroid derived 2, like 2
Synonyms: expressed sequence AI194320, AI194320, Nrf2
Source: MGI:108420
Biotype: protein coding gene
Pdk1
(Mus musculus)Gene
Name: pyruvate dehydrogenase kinase, isoenzyme 1
Synonyms: D530020C15Rik, RIKEN cDNA D530020C15 gene
Source: MGI:1926119
Biotype: protein coding gene
IFNG
(Homo sapiens)Gene
Name: interferon gamma
Synonyms: interferon, gamma, IFN-gamma, immune interferon, IMD69, IFG, IFI
Source: HGNC:5438
Biotype: protein coding gene
BIN1
(Homo sapiens)Gene
Name: bridging integrator 1
Synonyms: amphiphysin II, amphiphysin 2, DKFZp547F068, CNM2, AMPHL, amphiphysin-like protein, myc box-dependent-interacting protein 1, SH3P9, myc box dependent interacting protein 1, AMPH2, box dependant MYC interacting protein 1, MGC10367, box-dependent myc-interacting protein 1
Source: HGNC:1052
Biotype: protein coding gene
Ntrk2
(Rattus norvegicus)Gene
Name: neurotrophic receptor tyrosine kinase 2
Synonyms: Tkrb, trkB tyrosine kinase, trkB, GP145-TrkB/GP95-TrkB, neurotrophic tyrosine receptor kinase type 2, neurotrophic tyrosine kinase, receptor, type 2, trk-B, BDNF/NT-3 growth factors receptor, Neural receptor protein-tyrosine kinase (trkB)
Source: RGD:3213
Biotype: protein coding gene
TMED10
(Homo sapiens)Gene
Name: transmembrane p24 trafficking protein 10
Synonyms: p24delta, P24(DELTA), testicular tissue protein Li 206, S31III125, Tmp-21-I, 21 kDa transmembrane-trafficking protein, 21 kDa transmembrane trafficking protein, p23, transmembrane emp24 domain-containing protein 10, TMP21, transmembrane emp24-like trafficking protein 10, p24 family protein delta-1, transmembrane protein Tmp21, S31I125, p24delta1, p24d1
Source: HGNC:16998
Biotype: protein coding gene
Apoe
(Rattus norvegicus)Gene
Name: apolipoprotein E
Synonyms: apo-E, APOEA
Source: RGD:2138
Biotype: protein coding gene
Tnfrsf1a
(Mus musculus)Gene
Name: tumor necrosis factor receptor superfamily, member 1a
Synonyms: TNF-alpha-R1, TNF-R1, TNFalpha-R1, TNFR60, TNF-R55, TNF-alphaR1, TNFRI, TNF receptor alpha chain, TNFR-1, TNFRp55, p55, p55-R, TNF-R-I, Tnfr1, tumor necrosis factor receptor 2, TNFAR, CD120a, tumor necrosis factor receptor 1, Tnfr-2
Source: MGI:1314884
Biotype: protein coding gene
Nfe2l2
(Rattus norvegicus)Gene
Name: NFE2 like bZIP transcription factor 2
Synonyms: nrf2, nuclear factor erythroid 2-like 2, nuclear factor, erythroid derived 2, like 2, NF-E2-related factor 2, nuclear factor, erythroid 2-like 2, nuclear factor erythroid 2-related factor 2, NFE2-related factor 2
Source: RGD:620360
Biotype: protein coding gene
Casp3
(Rattus norvegicus)Gene
Name: caspase 3
Synonyms: caspase 3, apoptosis related cysteine protease, SCA-1, IRP, CPP-32, Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease), CPP32-beta, SREBP cleavage activity 1, Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease), CASP-3, MGC93645, Yama, cysteine protease CPP32, cysteine protease p32-beta, Lice, CPP32beta, apopain, caspase-3
Source: RGD:2275
Biotype: protein coding gene
Hap1
(Rattus norvegicus)Gene
Name: huntingtin-associated protein 1
Synonyms: HAP1-B, HAP1-A, HAP-1
Source: RGD:68327
Biotype: protein coding gene
Pdk
(Drosophila melanogaster)Gene
Name: Pyruvate dehydrogenase kinase
Synonyms: PDHK, pdk, BcDNA:LD09837, PDK, pyruvate dehydrogenase kinase, CG8808, DmPDK, DmPdk
Source: FB:FBgn0017558
Biotype: protein coding gene
Aldob
(Mus musculus)Gene
Name: aldolase B, fructose-bisphosphate
Synonyms: BC016435, Aldo-2, LIV10, Aldo2, cDNA sequence BC016435
Source: MGI:87995
Biotype: protein coding gene
Ntrk2
(Mus musculus)Gene
Name: neurotrophic tyrosine kinase, receptor, type 2
Synonyms: Tkrb, trkB, tyrosine protein kinase receptor, RIKEN cDNA C030027L06 gene, RATTRKB1, expressed sequence AI848316, TRKB1, trk-B, AI848316, C030027L06Rik
Source: MGI:97384
Biotype: protein coding gene
Ifngr1
(Mus musculus)Gene
Name: interferon gamma receptor 1
Synonyms: Nktar, CD119, Ifngr, IFN-gamma R, Ifgr, IFN-gammaR
Source: MGI:107655
Biotype: protein coding gene
Prnp
(Mus musculus)Gene
Name: prion protein
Synonyms: prion protein, structural locus, CD230, expressed sequence AA960666, PrPSc, expressed sequence AI325101, prion protein, scrapie incubation time regulation, Sinc, Prn, PrP, PrPC, Prn-p, Prn-i, scrapie incubation period, AA960666, AI325101
Source: MGI:97769
Biotype: protein coding gene
RELA
(Homo sapiens)Gene
Name: RELA proto-oncogene, NF-kB subunit
Synonyms: MGC131774, CMCU, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, NFKB3, nuclear factor NF-kappa-B p65 subunit, AIF3BL3, v-rel avian reticuloendotheliosis viral oncogene homolog A, NF-kappa-B p65delta3, p65, v-rel reticuloendotheliosis viral oncogene homolog A, NF-kappa-B transcription factor p65, v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)), v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65, transcription factor p65
Source: HGNC:9955
Biotype: protein coding gene
Ormdl3
(Mus musculus)Gene
Name: ORM1-like 3 (S. cerevisiae)
Synonyms: AI315223, expressed sequence AI315223, RIKEN cDNA 2810011N17 gene, LRRGT00183, 2810011N17Rik
Source: MGI:1913862
Biotype: protein coding gene
PRNP
(Homo sapiens)Gene
Name: prion protein (Kanno blood group)
Synonyms: CD230, PrP33-35C, GSS, MGC26679, major prion protein, prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia), PRIP, p27-30, KURU, PrP, prion protein PrP, PrPc, PrP27-30, AltPrP, prion-related protein, prion, CD230 antigen, alternative prion protein, CJD, prion protein, ASCR
Source: HGNC:9449
Biotype: protein coding gene
Gsap
(Mus musculus)Gene
Name: gamma-secretase activating protein
Synonyms: RIKEN cDNA A530088I07 gene, pigeon homolog (Drosophila), A530088I07Rik, Pion
Source: MGI:2442259
Biotype: protein coding gene
TIGAR
(Homo sapiens)Gene
Name: TP53 induced glycolysis regulatory phosphatase
Synonyms: fructose-2,6-bisphosphatase TIGAR, FR2BP, C12orf5, TP53-induced glycolysis regulatory phosphatase, TP53-induced glycolysis and apoptosis regulator, fructose-2,6-bisphosphate 2-phosphatase, transactivated by NS3TP2 protein, probable fructose-2,6-bisphosphatase TIGAR
Source: HGNC:1185
Biotype: protein coding gene
Ormdl1
(Mus musculus)Gene
Name: ORM1-like 1 (S. cerevisiae)
Synonyms: C730042F17Rik, RIKEN cDNA C730042F17 gene
Source: MGI:2181669
Biotype: protein coding gene
Rptor
(Mus musculus)Gene
Name: regulatory associated protein of MTOR, complex 1
Synonyms: Rap, RGD1311784, raptor, 4932417H02Rik, mKIAA1303, RIKEN cDNA 4932417H02 gene
Source: MGI:1921620
Biotype: protein coding gene
Rela
(Rattus norvegicus)Gene
Name: RELA proto-oncogene, NF-kB subunit
Synonyms: v-rel reticuloendotheliosis viral oncogene homolog A, nos2, v-rel reticuloendotheliosis viral oncogene homolog A (avian), nuclear factor kappaB subunit p65, nuclear factor kappa B subunit p65, NFkB, v-rel avian reticuloendotheliosis viral oncogene homolog A, transcription factor p65
Source: RGD:727889
Biotype: protein coding gene