Version: 8.1.0Date: Fri Apr 18 2025
Gene Biological Process: regulation of protein localization Subcellular Expression: plasma membrane
FLNA
(Homo sapiens)Gene
Name: filamin A
Synonyms: OPD, FLN-A, filamin-1, FLN, FLN1, XMVD, XLVD, filamin A, alpha, actin binding protein 280, FG syndrome 2, alpha filamin, MNS, filamin 1, DKFZp434P031, FMD, CSBS, FGS2, endothelial actin-binding protein, non-muscle filamin, OPD2, OPD1, NHBP, alpha-filamin, FLJ43642, filamin-A, ABPX, ABP-280, CVD1
Source: HGNC:3754
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
Apoe
(Mus musculus)Gene
Name: apolipoprotein E
Synonyms: expressed sequence AI255918, APOEA, AI255918
Source: MGI:88057
Biotype: protein coding gene
Bmp4
(Mus musculus)Gene
Name: bone morphogenetic protein 4
Synonyms: Bmp2b, bone morphogenetic protein 2b, BOMPR4A, Bmp2b-1, Bmp-4, bone morphogenetic protein 2b 1, Bmp2b1
Source: MGI:88180
Biotype: protein coding gene
CDC28
(Saccharomyces cerevisiae)Gene
Name: Cell Division Cycle
Synonyms: YBR160W, SRM5, HSL5, CDK1
Source: SGD:S000000364
Biotype: protein coding gene
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide, beta-amyloid peptide(1-42), preA4, beta-amyloid peptide(1-40), cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, AD1, alpha-sAPP, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), alzheimer disease amyloid protein, protease nexin-II, amyloid beta A4 protein, CTFgamma, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
HTT
(Homo sapiens)Gene
Name: huntingtin
Synonyms: LOMARS, huntington disease protein, HD, IT15, huntington disease gene homolog
Source: HGNC:4851
Biotype: protein coding gene
EGFR
(Homo sapiens)Gene
Name: epidermal growth factor receptor
Synonyms: PIG61, receptor tyrosine-protein kinase erbB-1, NNCIS, epidermal growth factor receptor tyrosine kinase domain, EGFR vIII, proto-oncogene c-ErbB-1, cell growth inhibiting protein 40, erb-b2 receptor tyrosine kinase 1, ERRP, ERBB, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), ERBB1, erythroblastic leukemia viral (v-erb-b) oncogene homolog, mENA, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell proliferation-inducing protein 61, HER1, NISBD2
Source: HGNC:3236
Biotype: protein coding gene
APOE
(Homo sapiens)Gene
Name: apolipoprotein E
Synonyms: LDLCQ5, LPG, apolipoprotein E3, apo-E, ApoE4, Alzheimer disease 2 (APOE*E4-associated, late onset), MGC1571, AD2
Source: HGNC:613
Biotype: protein coding gene
CFTR
(Homo sapiens)Gene
Name: CF transmembrane conductance regulator
Synonyms: CF, ABCC7, cystic fibrosis transmembrane conductance regulator, atp-binding cassette (sub-family c, member 7), MRP7, CFTR/MRP, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7, dJ760C5.1, ATP-binding cassette sub-family C member 7, ABC35, cystic fibrosis transmembrane conductance regulator, cystic fibrosis transmembrane conductance regulating, channel conductance-controlling ATPase, TNR-CFTR, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Source: HGNC:1884
Biotype: protein coding gene
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, TNFSF2, tumor necrosis factor-alpha, TNF, monocyte-derived, TNFA, TNF, macrophage-derived, tumor necrosis factor alpha, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
HTRA2
(Homo sapiens)Gene
Name: HtrA serine peptidase 2
Synonyms: serine proteinase OMI, Omi stress-regulated endoprotease, PARK13, protease, serine, 25, serine protease 25, high temperature requirement protein A2, OMI, serine protease HTRA2, mitochondrial, PRSS25, HtrA-like serine protease, MGCA8
Source: HGNC:14348
Biotype: protein coding gene
Flna
(Mus musculus)Gene
Name: filamin, alpha
Synonyms: filamin 1, dilated pupils 2, filamin-1, Dilp2, actin-binding protein 280, GENA 379, Fln1, RIKEN cDNA F730004A14 gene, F730004A14Rik, ABP-280, RGD1560614
Source: MGI:95556
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, Parkinson disease (autosomal dominant, Lewy body) 4, MGC110988, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, synuclein, alpha, alpha-synuclein, isoform NACP140, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
Tardbp
(Mus musculus)Gene
Name: TAR DNA binding protein
Synonyms: Tdp43, 1190002A23Rik, TDP-43, expressed sequence C85084, Tdp-43, RIKEN cDNA 1190002A23 gene, C85084
Source: MGI:2387629
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
BCL2
(Homo sapiens)Gene
Name: BCL2 apoptosis regulator
Synonyms: Bcl-2, protein phosphatase 1, regulatory subunit 50, Bcl-2a, B-cell CLL/lymphoma 2, PPP1R50, b-cell leukemia/lymphoma 2, Bcl-2ß, apoptosis regulator Bcl-2, BCL2, apoptosis regulator
Source: HGNC:990
Biotype: protein coding gene
Htt
(Mus musculus)Gene
Name: huntingtin
Synonyms: C430023I11Rik, Huntington disease (human), expressed sequence AI256365, Huntington disease gene homolog, RIKEN cDNA C430023I11 gene, htt, HD, Hd, Hdh, IT15, AI256365
Source: MGI:96067
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, cerebrovascular amyloid peptide, Alzheimer disease amyloid beta protein, protease nexin II, AL024401, RIKEN cDNA E030013M08 gene, expressed sequence AL024401, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
HSF1
(Saccharomyces cerevisiae)Gene
Name: Heat Shock transcription Factor
Synonyms: YGL073W, EXA3, MAS3
Source: SGD:S000003041
Biotype: protein coding gene
Actb
(Mus musculus)Gene
Name: actin, beta
Synonyms: A-X actin-like protein, E430023M04Rik, RIKEN cDNA E430023M04 gene, Actx, melanoma X-actin, beta-actin
Source: MGI:87904
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: tyrosine-protein kinase mTOR, mechanistic target of rapamycin, rapamycin and FKBP12 target 1, rapamycin target protein 1, mammalian target of rapamycin, rapamycin associated protein FRAP2, FRAP1, RAFT1, FRAP2, FKBP12-rapamycin complex-associated protein 1, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, FRAP, SKS, RAPT1, serine/threonine-protein kinase mTOR, FKBP-rapamycin associated protein, FK506 binding protein 12-rapamycin associated protein 1, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
Tlr4
(Mus musculus)Gene
Name: toll-like receptor 4
Synonyms: lipopolysaccharide response, RAS-like, family 2, locus 8, Lps, Rasl2-8
Source: MGI:96824
Biotype: protein coding gene
Tgfb1
(Mus musculus)Gene
Name: transforming growth factor, beta 1
Synonyms: Tgfb-1, TGF-beta 1, Tgfb, TGFbeta1, TGF-beta1
Source: MGI:98725
Biotype: protein coding gene
HRAS
(Homo sapiens)Gene
Name: HRas proto-oncogene, GTPase
Synonyms: HAMSV, H-RASIDX, Ras family small GTP binding protein H-Ras, GTPase KRas, RASH1, Harvey rat sarcoma viral oncoprotein, ha-Ras, GTP- and GDP-binding peptide B, transformation gene: oncogene HAMSV, p19 H-RasIDX protein, c-Ki-ras, H-Ras-1, Ha-Ras1 proto-oncoprotein, C-H-RAS, p21ras, N-RAS, c-has/bas p21 protein, HRAS1, Harvey rat sarcoma viral oncogene homolog, RASK2, GTPase HRas, CTLO, Ki-Ras, c-K-ras, K-RAS, c-ras-Ki-2 activated oncogene, C-BAS/HAS, K-Ras 2, KRAS, C-HA-RAS1, KRAS2, transforming protein p21, v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Source: HGNC:5173
Biotype: protein coding gene
HLA-DRB1
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 1
Synonyms: MHC class II HLA-DRw10-beta, HLA-DRB1*, leucocyte antigen DRB1, DW2.2/DR2.2, FLJ76359, HLA-DR-beta 1, leucocyte antigen DR beta 1 chain, MHC class II antigen, major histocompatibility complex, class II, DR beta 1 precursor, DRw8, SS1, DR16, DR-8, MHC class II HLA-DR beta 1 chain, lymphocyte antigen DRB1, DRB1, DR-16, DR1, HLA class II histocompatibility antigen, DR-1 beta chain, MHC class II antigen HLA-DR13, FLJ75017, DR5, HLA class II antigen beta chain, DR8, DRw11, DRw10, MHC class II HLA-DR-beta cell surface glycoprotein, human leucocyte antigen DRB1, HLA-DR1B, HLA-DRB
Source: HGNC:4948
Biotype: protein coding gene
C9orf72
(Homo sapiens)Gene
Name: C9orf72-SMCR8 complex subunit
Synonyms: FTDALS, chromosome 9 open reading frame 72, DENNL72, MGC23980, FTDALS1, hypothetical protein LOC203228, uncharacterized protein C9orf72, DENND9, guanine nucleotide exchange C9orf72, RP11-27J8.2, ALSFTD, guanine nucleotide exchange factor C9orf72
Source: HGNC:28337
Biotype: protein coding gene
ACTB
(Homo sapiens)Gene
Name: actin beta
Synonyms: actin, cytoplasmic 1, DDS1, beta cytoskeletal actin, CSMH, actin, beta, PS1TP5BP1, BNS, PS1TP5-binding protein 1, BKRNS, I(2)-actin, BRWS1, THC8
Source: HGNC:132
Biotype: protein coding gene
Apc
(Mus musculus)Gene
Name: APC, WNT signaling pathway regulator
Synonyms: CC1, expressed sequence AI047805, AI047805, AU020952, adenomatosis polyposis coli, Min, expressed sequence AU020952, RATAPC, multiple intestinal neoplasia, AW124434, expressed sequence AW124434
Source: MGI:88039
Biotype: protein coding gene
Cftr
(Mus musculus)Gene
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7, AW495489, expressed sequence AW495489, RGD1561193
Source: MGI:88388
Biotype: protein coding gene
Ifng
(Mus musculus)Gene
Name: interferon gamma
Synonyms: If2f, IFN-gamma, IFNG2, Ifg
Source: MGI:107656
Biotype: protein coding gene
Ptgs2
(Mus musculus)Gene
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX-2, Cox-2, PHS II, Cox2, Pghs2, cyclooxygenase-2, prostaglandin G/H synthase, COX2, PHS-2, PGHS-2, cyclooxygenase 2, Tis10
Source: MGI:97798
Biotype: protein coding gene
Krt5
(Mus musculus)Gene
Name: keratin 5
Synonyms: Sak57, Tfip8, RIKEN cDNA 3300001P10 gene, 3300001P10Rik, AW146334, expressed sequence AW146334, Krt2-5, K5, keratin complex 2, basic, gene 5, tuftelin interacting protein 8, CK-5
Source: MGI:96702
Biotype: protein coding gene
PSEN1
(Homo sapiens)Gene
Name: presenilin 1
Synonyms: presenilin-1 isoform I-467, AD3, PS-1, FAD, ACNINV3, familial Alzheimer Disease, CMD1U, presenilin 1 (Alzheimer disease 3), S182, presenilin-1, PSNL1, PS1
Source: HGNC:9508
Biotype: protein coding gene
Prkn
(Mus musculus)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkinson disease (autosomal recessive, juvenile) 2, parkin, Park2, Parkin, Park
Source: MGI:1355296
Biotype: protein coding gene
Brca1
(Mus musculus)Gene
Name: breast cancer 1, early onset
Synonyms: BRCA-1
Source: MGI:104537
Biotype: protein coding gene
ACSL4
(Homo sapiens)Gene
Name: acyl-CoA synthetase long chain family member 4
Synonyms: LACS4, lignoceroyl-CoA synthase, FACL4, mental retardation, X-linked 63, long-chain fatty-acid-Coenzyme A ligase 4, acyl-CoA synthetase long-chain family member 4, mental retardation, X-linked 68, MRX63, long-chain acyl-CoA synthetase 4, MRX68, XLID63, arachidonate--CoA ligase, LACS 4, fatty-acid-Coenzyme A ligase, long-chain 4, ACS4, acyl-CoA synthetase 4, long-chain-fatty-acid--CoA ligase 4
Source: HGNC:3571
Biotype: protein coding gene
Ctnnb1
(Mus musculus)Gene
Name: catenin beta 1
Synonyms: beta-catenin, beta catenin, Catnb, batface, catenin beta, Bfc, catenin (cadherin associated protein), beta 1
Source: MGI:88276
Biotype: protein coding gene
Brca1
(Rattus norvegicus)Gene
Name: BRCA1, DNA repair associated
Synonyms: BRCA-1, breast cancer 1, early onset, breast cancer type 1 susceptibility protein homolog, breast cancer 1, RING-type E3 ubiquitin transferase BRCA1
Source: RGD:2218
Biotype: protein coding gene
Snca
(Mus musculus)Gene
Name: synuclein, alpha
Synonyms: alpha-Syn, alphaSYN, alpha-synuclein
Source: MGI:1277151
Biotype: protein coding gene
VCP
(Homo sapiens)Gene
Name: valosin containing protein
Synonyms: epididymis secretory protein Li 70, IBMPFD, valosin-containing protein, HEL-S-70, MGC148092, CMT2Y, TERA, transitional endoplasmic reticulum ATPase, FTDALS6, yeast Cdc48p homolog, p97, 15S Mg(2+)-ATPase p97 subunit, HEL-220, MGC8560, CDC48, TER ATPase, MGC131997, ALS14, IBMPFD1, epididymis luminal protein 220
Source: HGNC:12666
Biotype: protein coding gene
Fbn1
(Mus musculus)Gene
Name: fibrillin 1
Synonyms: expressed sequence AI536462, Fib-1, tight skin, AI536462, Tsk
Source: MGI:95489
Biotype: protein coding gene
Lep
(Mus musculus)Gene
Name: leptin
Synonyms: OB, ob, obese
Source: MGI:104663
Biotype: protein coding gene
Wnt3a
(Mus musculus)Gene
Name: wingless-type MMTV integration site family, member 3A
Synonyms: vestigial tail, Wnt-3a, vt
Source: MGI:98956
Biotype: protein coding gene
Pparg
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: PPARgamma2, Nr1c3, Ppar-gamma2, PPARgamma, PPAR-gamma
Source: MGI:97747
Biotype: protein coding gene
BMP4
(Homo sapiens)Gene
Name: bone morphogenetic protein 4
Synonyms: MCOPS6, bone morphogenetic protein 2B, BMP2B, bone morphogenetic protein 4 preproprotein, OFC11, BMP-2B, BMP-4, ZYME, BMP2B1
Source: HGNC:1071
Biotype: protein coding gene
CDH1
(Homo sapiens)Gene
Name: cadherin 1
Synonyms: BCDS1, LCAM, ECAD, calcium-dependent adhesion protein, epithelial, cell-CAM 120/80, CDHE, cadherin 1, E-cadherin (epithelial), CAM 120/80, UVO, uvomorulin, cadherin 1, type 1, E-cadherin (epithelial), E-cadherin 1, cadherin 1, type 1, E-Cadherin, cadherin-1, CD324, epithelial cadherin, Arc-1, truncated cadherin 1 type 1
Source: HGNC:1748
Biotype: protein coding gene
Nrxn1
(Mus musculus)Gene
Name: neurexin I
Synonyms: RIKEN cDNA 9330127H16 gene, neurexin I beta, Nrxn1b, RIKEN cDNA A230068P09 gene, RIKEN cDNA 1700062G21 gene, 1700062G21Rik, neurexin I alpha, mKIAA0578, alpha-latrotoxin receptor (calcium-dependent), A230068P09Rik, 9330127H16Rik
Source: MGI:1096391
Biotype: protein coding gene
Lepr
(Mus musculus)Gene
Name: leptin receptor
Synonyms: Modb1, leptin receptor gene-related protein, OB-RGRP, LEPROT, obese-like, obl, Leprb, Fa, diabetes, db, Obr
Source: MGI:104993
Biotype: protein coding gene
p53
(Drosophila melanogaster)Gene
Name: p53
Synonyms: CG33336, CG10873, dp53, DMP53, Dp53, P53, prac, D-p53, dmp53, Dmp53, DmP53, Dm-P53, dmP53, protein 53, CG31325, p53-like regulator of apoptosis and cell cycle, Drosophila p53
Source: FB:FBgn0039044
Biotype: protein coding gene